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Microbiome composition in mice varies based on sampling time: study

The microbiome plays a significant role in shaping health outcomes, including the development of diseases such as neurodegenerative disorders. However, microbiome research is facing a reproducibility crisis, with factors like diet, exercise, and now circadian rhythms impacting the composition of bacteria in the body. Researchers have found that the time of day at which experiments…

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Organization issues clinical practice guideline for the treatment of hemophilia

The International Society on Thrombosis and Haemostasis issued a clinical practice guideline for the treatment of congenital hemophilia, focusing on hemophilia A and B. The guideline recommends prophylaxis over episodic treatment for severe and moderately severe cases without inhibitors. It also provides guidance on the use of factor concentrates, bypassing agents, nonfactor therapy, and immune…

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Study uncovers the role of mGluR1 in pruning early neural connections

The brain goes through a process of pruning, removing unnecessary connections between neurons to make way for long-lasting circuits. Assistant Professor Gabrielle Pouchelon studies how these early connections affect brain development and dysfunction. Her team discovered that a receptor protein named mGluR1 regulates the timing of these connections in mice brains. Without mGluR1, connections in…

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Parental Smoking Linked to Increased MS Risk in Offspring

A multinational study showed that exposure to parental smoking during pregnancy or early childhood increases the risk of developing multiple sclerosis (MS) later in life. Previous research focused on active smoking as a risk factor for MS, but little was known about parental smoking and MS risk. The ongoing Environmental Risk Factors In Multiple Sclerosis…

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South Korea approves first local skin cancer detection AI

LifeSemantics, a Korean digital health company, gained approval for an AI-powered skin cancer diagnosis solution in South Korea. The canofyMD SCAI app uses convolutional neural networks to identify different types of skin cancer and benign tumors. Clinical trials showed promising results with 80.9% diagnostic accuracy. The company plans to launch the app commercially by the…

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Interventions needed to overcome racial, ethnic disparities in depression care among youth

Children and adolescents face significant racial and ethnic disparities in depression care, leading to increased risks such as school failure, substance abuse, and suicide. Studies show that youths from underrepresented groups are more susceptible to self-stigma and receive fewer mental health services compared to white youths. Cultural modifications to therapy interventions and community-based programs have…

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Dutch expert sees parallels to Q fever outbreaks

A regular update on the H5N1 bird flu outbreak in dairy cows in the U.S. is being provided by STAT. Pathologist Thijs Kuiken draws parallels with a past Q fever epidemic in the Netherlands, emphasizing the need to address animal health problems as public health concerns. Concerns are raised about the lack of urgency and…

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AI model finds the cancer clues at lightning speed

Researchers at the University of Gothenburg have developed an AI model, named Candycrunch, that can detect cancer through sugar analyses by mass spectrometry. The AI model is faster and more accurate in identifying abnormalities than the current semi-manual method. It has been trained using a database of over 500,000 examples and can determine the exact…

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Regulatory T cells exist as large, mobile population that travels through body to repair damaged tissue

A recent study in Immunology found that regulatory T cells (Treg) are a large, mobile population that continuously travels through the body to repair tissue. These cells contribute to physiological balance, affecting insulin sensitivity, muscle repair, and brain cell differentiation. The study explored Treg populations in various tissues, finding similarities in their genetic requirements and…

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Is Screen Time Making Kids Nearsighted?

Prolonged screen time in children and adolescents is linked to a higher risk of developing myopia, with computers and televisions having the most significant impact on eye health. A meta-analysis of 19 studies involving over 100,000 participants found a strong association between screen time and myopia. Each additional hour spent on screens per day increased…

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Healthcare Moves: A Monthly Summary of Hires and Layoffs

The healthcare hiring roundup highlights recent executive appointments, resignations, and layoffs in the healthcare industry. The American Medical Association welcomed a new president and named another for next year. Knownwell announced its first round of C-suite hires. Moximed appointed a new CEO, Mount Sinai Health System named a new CFO, RhythmX AI welcomed a new…

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Sidecar Health scores $165M for employer health insurance plans

Sidecar Health, an insurance startup focusing on price transparency and direct payments for care, raised $165 million in Series D financing led by Koch Disruptive Technologies. They plan to expand into Florida and partner with Koch Industries in providing medical insurance for a segment of their workforce. Sidecar’s members customize their annual healthcare coverage and…

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SCOTUS Ruling Strips Power From Federal Health Agencies

The Supreme Court overturned a 40-year-old legal precedent requiring judges to defer to federal agency expertise, causing uncertainty in government operations. The Court also avoided ruling on a case in Idaho regarding abortion and emergency care. Other recent rulings included a decision on opioid settlements and social media regulations. The first general-election debate for the…

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Conferences led by patients facilitate democratic decision making in healthcare

Oluwafemi Ajayi, Gail Sickle, and Patrick Gee are patient leaders in healthcare, along with Hetty Mulhall and Dawn P. Richards. They believe that patient-led conferences can promote democratic decision-making in healthcare. Sara Riggare is a researcher in this field. Their work, published in BMJ in 2024, highlights the importance of involving patients in decision-making processes…

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Preconception intake of calcium and zinc linked to lower risk of hypertensive disorders of pregnancy

Higher intake of calcium and zinc before conceiving can reduce the risk of hypertensive disorders during pregnancy, according to research. Preconception nutrition is crucial for a healthy pregnancy, highlighting the importance of adequate intake of essential minerals like calcium and zinc. Studies show that higher pre-conception intake of these minerals is associated with a lower…

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Europe Endorses Its First mRNA Vaccine for RSV

The EMA CHMP has recommended the marketing authorization for the mRNA RSV vaccine mRESVIA to protect adults aged 60 or older from lower respiratory tract disease caused by RSV. RSV is a contagious respiratory virus that can lead to serious consequences in older adults. The vaccine, mRNA-1345, targets the F glycoprotein of RSV to prevent…

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Why Insurers Beat CMS In the MA Star Ratings Battle

Medicare Advantage insurers won a victory as CMS agreed to recalculate Star Ratings following lawsuits from SCAN Health Plan and Elevance Health alleging improper calculations. Star Ratings inform beneficiaries of plan quality and impact funding, with higher ratings receiving more funding. CMS updated how Star Ratings are calculated using the Guardrail Rule to cap cut…

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ASH to present honorific awards to ‘visionary’ hematologists

The ASH Annual Meeting will honor several notable hematologists for their contributions to the field. Among the recipients are Éliane Gluckman for her work in cord blood transplantation, Stuart Orkin and John Tisdale for advancements in hemoglobin disorders treatment, James George for promoting diversity in hematology, Ami Bhatt for genomic research on the microbiome, Sean…

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An ALS moonshot plan barely gets off the ground

The National Academies of Sciences, Engineering, and Medicine released a report on transforming ALS into a manageable, chronic disease within 10 years, but it falls short in accelerating treatment development. ALS is a devastating condition with no effective treatments for 99% of patients. The report focuses on improving access to care, genetic testing, and caregiver…

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Hospital doctors in Wales vote to accept pay offers

Consultants, junior doctors, and SAS doctors in Wales have accepted the government’s pay offers, ending three separate pay disputes. Junior doctors in Wales voted to accept an additional 7.4%, bringing the total uplift to 12.4% for the 2023-24 financial year, with the rise backdated to April 2023. Consultants also voted to accept a revised pay…

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Is Semaglutide Anti-inflammatory?

Research presented at the European Atherosclerosis Society 2024 showed that the anti-obesity drug semaglutide led to significant reductions in the inflammatory marker high-sensitivity C-reactive protein (CRP) in patients with overweight or obesity, regardless of weight loss. The SELECT trial involving over 17,600 patients with cardiovascular disease found that semaglutide lowered CRP levels by 38% compared…

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Pivot Podcast: The Evolution of Pharmacies with Rick Ratliff

The pharmacy industry is experiencing significant changes, with independent pharmacies closing and retail pharmacies struggling. New medication delivery models, like Mark Cuban’s Cost Plus Drug Company and Amazon, are emerging. The pandemic highlighted the valuable role of pharmacists in administering vaccines. In the final episode of Season 2 of the Pivot podcast, Rick Ratliff, former…

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News Flash! Beware Jumping Leeches in Madagascar

Scientists have discovered a species of leech in the rainforests of Madagascar that can jump and soar in the air with acrobatic grace. This behavior, captured on film for the first time, has intrigued the scientific community and sheds light on previously undocumented behaviors of these creatures. The purpose of these jumps, whether to ambush…

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Care enablement company Fabric acquires Walmart’s MeMD

Fabric, a healthcare technology company, has acquired Walmart’s telehealth platform MeMD. MeMD offers virtual medical and behavioral health services to corporate clients, with 24/7 on-demand care and a care coordination team. Fabric uses conversational AI to identify patients’ symptoms and guide them to appropriate care settings. Through the acquisition, Fabric aims to expand its offerings…

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