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Blood test detects Parkinson’s years before symptoms appear using RNA markers

, 2025-04-15 00:42:00 Scientists have developed a fast, non-invasive blood test that can detect Parkinson’s disease before tremors begin. By measuring RNA fragments that reflect brain pathology, the test offers new hope for early diagnosis and targeted intervention. Study: Pre-symptomatic Parkinson’s disease blood test quantifying repetitive sequence motifs in transfer RNA fragments. Image Credit: Kateryna Kon /…

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Canada, with court order, advances an antitrust probe into Express Scripts

Ed Silverman , 2025-04-14 17:05:00 Canadian officials have obtained a court order that requires Express Scripts to produce documents in connection with an investigation into whether the pharmacy benefits manager violated antitrust laws. The Competition Bureau is examining whether the company forced or induced Canadians to use its own pharmacies. Express Scripts operates four mail-order…

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CONSORT 2025 explanation and elaboration: updated guideline for reporting randomised trials

Sally Hopewell, An–Wen Chan, Gary S Collins, Asbȷorn Hrobȷartsson, David Moher, Kenneth F Schulz, Ruth Tunn, Rakesh Aggarwal, Michael Berkwits, Jesse A Berlin, Nita Bhandari, Nancy J Butcher, Marion K Campbell, Runcie C W Chidebe, Diana Elbourne, Andrew Farmer, Dean A Fergusson, Robert M Golub, Steven N Goodman, Tammy C Hoffmann, John P A Ioannidis,…

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Analysis reveals one firearm injury was treated every 30 minutes in emergency departments in 10 jurisdictions

, 2025-04-14 21:00:00 Credit: Unsplash/CC0 Public Domain A cross-sectional analysis of firearm injury-related emergency department (ED) visits found that between 2018 and 2023, there was approximately one firearm injury ED visit every 30 minutes in the 10 jurisdictions studied. The analysis also found that rates of firearm-related ED visits were often highest during evenings, weekends,…

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FDA OKs Vyvgart Hytrulo Prefilled Syringe for gMG, CIDP

, 2025-04-14 14:35:00 The US Food and Drug Administration (FDA) has approved a prefilled syringe for self-injection of efgartigimod alfa and hyaluronidase-qvfc (Vyvgart Hytrulo, argenx) in the treatment of adults with generalized myasthenia gravis (gMG) who are anti-acetylcholine receptor antibody positive and adults with chronic inflammatory demyelinating polyneuropathy (CIDP).  The prefilled syringe will be available as…

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How AI Is Paying Off: 5 Wins at Advocate Health

Katie Adams , 2025-04-09 00:56:00 There is much variation across the country in terms of how far along health systems are in their AI deployment journey, with some hospitals still in cautious experimentation mode and others already scaling tools across multiple clinical and operational settings, noted Andy Crowder, chief digital officer at Advocate Health, in…

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Trump administration launches probe into pharmaceutical imports

Ed Silverman , 2025-04-14 20:49:00 The Trump administration disclosed it formally opened an investigation into the extent to which the importation of certain pharmaceuticals may threaten national security, a move that is a widely anticipated prelude to imposing tariffs on a potentially large number of medicines. In a Federal Register notice published on Monday, the…

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Optical genome mapping technology shows promise for diagnosis, prognosis and therapeutic options of multiple myeloma

, 2025-04-14 20:40:00 Graphical abstract. Credit: The Journal of Molecular Diagnostics (2025). DOI: 10.1016/j.jmoldx.2025.01.003 Researchers have demonstrated the potential of the innovative optical genome mapping (OGM) technique for the diagnosis, prognosis, and therapeutic management of multiple myeloma. This new study in The Journal of Molecular Diagnostics, details how this novel method can establish the cytogenomic…

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Pregnancy complications may predict future heart disease risk

, 2025-04-14 16:10:00 Complications during pregnancy (or adverse pregnancy outcomes), like gestational diabetes and newly developed high blood pressure, act as nature’s stress test and may uncover an individual’s risk for heart disease later in life, according to new research published in the JACC, the flagship journal of the American College of Cardiology. The study…

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FDA Issues Warning About Counterfeit Ozempic

, 2025-04-14 19:02:00 The U.S. Food and Drug Administration (FDA) and Novo Nordisk are warning people not to use counterfeit semaglutide 1.0 mg (Ozempic injection) found in the US drug supply chain.  Novo Nordisk notified the FDA on April 3, 2025 that several hundred units of the fake product had been distributed outside the company’s…

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Second Child Dies Of Measles In Texas;Victim Was Unvaccinated

, 2025-04-07 07:04:00 A school-aged child has died from complications of measles in Texas, marking the second death in this year’s outbreak, which has sickened 481 people and hospitalized 56 since January. The unidentified victim who died of lung failure was not vaccinated and did not have any previous health conditions, health officials revealed. Measles…

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How Technology and Value-Based Models Will Reshape Healthcare by 2035

Mansoor Khan , 2025-04-14 14:19:00 As we navigate through 2025, the American healthcare system stands at a critical juncture. The demographic shifts that have been gradually unfolding are now accelerating, creating challenges that will fundamentally reshape how care is delivered over the next decade. Having worked with healthcare organizations across the country, I’ve observed firsthand…

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Christi Grimm interview, Crisis at HHS, Medicare rates

Bob Herman , 2025-04-14 17:38:00 This is the online version of STAT’s email newsletter Health Care Inc., delivered to your inbox every Monday. Sign up here.  STAT has just won a National Magazine Award for General Excellence. It’s a testament to just how hard everyone here works, and if you’re a subscriber, hopefully it shows you’re…

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New tool guides families on RSV immunization

, 2025-04-14 18:10:00 Credit: Unsplash/CC0 Public Domain Researchers from the Wesfarmers Center of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, have launched an online guidance tool designed to help families and health-care providers in WA learn the best way to protect babies and young children against life-threatening respiratory syncytial virus (RSV)….

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CT Linked to Future Cancer Risk

, 2025-04-14 15:00:00 TOPLINE: CT examinations performed on 62 million patients in the United States during 2023 are projected to result in approximately 103,000 future cancer cases. Adults account for 91% of projected radiation-induced cancers despite higher per-examination risk in children. METHODOLOGY: Approximately 93 million CT examinations are performed on 62 million patients annually in…

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Pfizer Stops Work on Oral GLP-1 Obesity Drug After Safety Signal Surfaces in Clinical Trial

Frank Vinluan , 2025-04-14 16:38:00 Pfizer is playing catch-up in the crowded field of obesity medicines, but it hoped to compete with a daily pill alternative to currently available injectable GLP-1 products. Instead, Pfizer is stopping development of its drug, danuglipron, after a liver complication emerged in a clinical trial. The pharmaceutical giant was evaluating…

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Trump elimina la oficina que establece los niveles de pobreza vinculados a servicios para 80 millones de personas

Arthur Allen , 2025-04-11 09:01:00 Los despidos del presidente Donald Trump en el Departamento de Salud y Servicios Humanos (HHS) incluyeron a toda la oficina que establece las pautas federales de pobreza. Estas pautas determinan si decenas de millones de estadounidenses son elegibles para programas de salud como Medicaid, asistencia alimentaria, cuidado infantil y otros…

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Readout Newsletter: Pfizer, Verve, NIH, CRISPR

Meghana Keshavan , 2025-04-14 14:13:00 Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Morning. Today, we discuss interesting new gene-editing data from Verve, see the NIH starting to convene advisory councils again, and more. The need-to-know this morning Third Harmonic Bio, a company that has…

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New device improves mobility among seniors through arm movement

, 2025-04-14 15:01:00 Credit: University of Maine Aging can impair people’s ability to maintain their balance while walking, increasing the risk for falls and injuries. One method for improving motor skills for walking is through training or rehabilitating gait—a person’s walking pattern. With the population of Maine—the oldest in the nation—growing older, a team of…

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New Bill Rocks the Boat

, 2025-04-14 14:10:00 A renewed effort to modernize and stabilize Medicare reimbursement for radiation therapy services is underway.  In mid-March, members of Congress reintroduced bipartisan federal legislation that would shift Medicare reimbursement for radiation oncology services from quantity-based payments to episode-based payments and help stabilize the declining rates of reimbursement in the field.  The Radiation…

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Medication Adherence and Deprescribing Programs Aren’t Enough for Today’s Polypharmacy Patients

Adva Tzuk Onn , 2025-04-14 13:05:00 As the Boomer generation ages, the prevalence of polypharmacy — patients taking multiple medications to manage chronic conditions — is surging. Nearly 40% of older adults take five or more medications, a number that has tripled in the last two decades. While polypharmacy can be necessary, it also significantly increases the…

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A UK wealth tax for better health

Kate E Pickett, David Taylor-Robinson , 2025-04-14 09:31:00 Kate E Pickett, professor of epidemiology1, David Taylor-Robinson, professor of public health and policy2 1Health Sciences, University of York, York, UK 2University of Liverpool, Liverpool, UK Correspondence to: K E Pickett kate.pickett{at}york.ac.uk Revenue could reduce funding gaps and inequalities The UK’s health and social care services are…

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Common medications may delay Parkinson’s onset

, 2025-04-14 11:59:00 Dot plots showing the association of PD AAO with a) statin intake, b) NSAID intake, c) adrenergic blockers intake, and d) smoking history, which were the four strongest independent predictors of AAO in the multiple regression analysis. Credit: Journal of Neurology (2025). DOI: 10.1007/s00415-025-12989-2 In a new Cedars-Sinai study of Parkinson’s disease…

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Navigate Hypertensive Disorders During and After Pregnancy

, 2025-04-14 11:44:00 “Roughly 6% of all maternal deaths in the United States are due to a hypertensive disorder of pregnancy,” said Joan Briller, MD, of the University of Illinois, Chicago, in a presentation at the American College of Physicians (ACP-IM) Internal Medicine Meeting 2025. This estimate, based on data from the Centers for Disease…

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What Are the Best Medical Coding Outsourcing Companies?

Luidgi Faubert , 2025-04-09 13:34:00 Medical coding is a complex yet essential part of any health care facility. The impact of inaccurate coding can directly impact revenue cycles, compliance and patient care. Fortunately, errors can be mitigated with the help of a specialized medical coding partner. These organizations possess the expertise, technology and commitment to…

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