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New genetic clues uncovered in epilepsy drug resistance

, 2025-04-16 06:11:00 Certain common genetic changes might make some people with focal epilepsy less responsive to seizure medications, finds a new global study led by researchers at UCL and UTHealth Houston. Focal epilepsy is a condition where seizures start in one part of the brain. It is the most common type of epilepsy. Antiseizure…

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How Stress Shapes Cancer’s Course

, 2025-04-16 06:32:00 About two millennia ago, the Greek physicians Hippocrates and Galen suggested that melancholia — depression brought on by an excess of “black bile” in the body — contributed to cancer. Since then, scores of researchers have investigated the association between cancer and the mind, with some going as far as to suggest…

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University College Dublin’s 2025 Innovation Awardees announced by NovaUCD

Editorial Staff , 2025-04-15 07:20:00 Skin and wound healing research expert and entrepreneur receives the main 2025 NovaUCD Innovation Award The recipients of University College Dublin’s (UCD) annual innovation awards, which highlight successes made in areas of knowledge transfer, consultancy, entrepreneurship and the promotion of an innovation culture, by members of the UCD research, innovation…

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Trump administration halts multicenter TB study led by Harvard

Mike Damiano — Boston Globe , 2025-04-15 15:24:00 A top scientist at Harvard who has spent years unraveling the mysteries of tuberculosis woke up Tuesday morning and discovered an order from the federal government telling her to halt her research. The stop-work order from the National Institutes of Health arrived hours after the Trump administration’s antisemitism…

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When people repeatedly read sentences, they get faster and more accurate, showing the brain improves with practice

, 2025-04-16 05:20:00 Credit: Tima Miroshnichenko from Pexels Have you ever noticed yourself speeding up and getting better at repetitive tasks over time? Researchers from the Faculty of Arts at Charles University have unveiled insights into why this happens during reading tasks, revealing that it’s primarily due to genuine learning rather than mere boredom. The…

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Combat Post–Bariatric Surgery Weight Regain With GLP-1 RAs

, 2025-04-15 12:00:00 TOPLINE:  Treatment with glucagon-like peptide 1 receptor agonists (GLP-1 RAs), including liraglutide or semaglutide, for 12 months enabled patients to lose nearly all the weight they had regained after bariatric surgery. METHODOLOGY:  Researchers conducted a single-centre retrospective study to examine the efficacy and safety of 12 months of treatment with GLP-1 RAs…

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The Future of Healthcare Cybersecurity: Preemptively Defending Against Emerging Threats

Brad LaPorte , 2025-04-15 13:05:00 Cyberattacks targeting the healthcare industry are happening more frequently, and they’re becoming more sophisticated and damaging. There are many reasons for this, of course. But leading the pack are attacker (and attack) sophistication and the arrival of AI. There are also reasons that are unique to the healthcare sector, including…

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Memorial for Palestinian healthcare workers

Editorial Staff , 2025-04-15 07:30:00 Event was organised by Caoimhe Butterly who had worked in Gaza as an EMT A group of Irish healthcare workers held a memorial outside the Irish Red Cross office on Merrion Square last week for the Palestinian paramedics killed in Gaza. It was organised by Caoimhe Butterly who had worked…

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Phantom Neuro secures $19M to advance human-machine technology

, 2025-04-15 17:44:00 Phantom Neuro, a neurotechnology company that offers a muscle-machine interface for controlling prosthetic limbs and robotic exoskeletons, announced an oversubscribed $19 million Series A funding round, bringing its total raise to $28 million. Ottobock led the round with participation from existing investors Draper Associates, Time BioVentures, Breakout Ventures, Risk and Return, and…

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Trump executive order targets health care costs, drug prices

Tara Bannow and Anil Oza , 2025-04-15 23:13:00 Tara Bannow covers hospitals, providers, and insurers. You can reach Tara on Signal at tarabannow.70. President Trump unveiled a wide-ranging executive order on Tuesday that aims to lower drug prices, boost transparency into fees charged by middlemen, and limit Medicare payments for outpatient services provided by hospitals….

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Multicountry Outcomes in Grade 3 Placenta Accreta

, 2025-04-15 12:00:00 TOPLINE: Severe postpartum haemorrhage (PPH) in grade 3 placenta accreta spectrum (PAS) varied significantly by country, with Italy showing the best outcomes due to standardised hysterectomy protocols. METHODOLOGY: This multicountry study compared the clinical management and outcomes of grade 3 PAS in three studies conducted across the United Kingdom (2010-2011), France (2013-2015),…

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Consultation opens ahead of AI framework for healthcare

Michael McHale , 2025-04-15 07:30:00 HIQA to lead on development of guidelines that will encourage best practice on responsible use of AI in health and social care settings Work is underway to inform the development of a national framework for the use of artificial intelligence (AI) in health and social care. The Health Information and…

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Reimagine Care, MedStar Health partner to integrate oncology care platform

, 2025-04-15 19:14:00 Home care cancer-focused platform Reimagine Care announced it is joining forces with healthcare system MedStar Health to integrate its on-demand oncology care platform into the health system’s cancer care delivery model and assist patients with the transition from in-clinic care to the home. Reimagine Care’s patient-centered model provides patients with customized all-inclusive…

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Vaccine advisory panel meets, avoiding conflict with RFK Jr.

Jason Mast , 2025-04-15 23:27:00 A  meeting of vaccine advisers long targeted by health secretary Robert F. Kennedy Jr. unfolded Tuesday seemingly without fireworks or interference, although the new administration’s imprint could be seen from the start, when staff for the Centers for Disease Control and Prevention, gutted by layoffs, struggled to get a livestream…

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Complete reporting of clinical trials requires more than journal articles

Evan Mayo-Wilson , 2025-04-14 22:00:00 Evan Mayo-Wilson, associate professor of epidemiology Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA Evan.Mayo-Wilson{at}unc.edu First published in 1996, CONSORT (Consolidated Standards of Reporting Trials) emphasised the importance of accurate and complete reporting of randomised clinical trials.1 Journal articles were the…

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Blood Test Predicts Melanoma Recurrence

, 2025-04-15 22:30:00 TOPLINE: Droplet digital polymerase chain reaction (PCR) measurements of circulating tumor DNA (ctDNA) identify patients with stage III melanoma who are at high risk for early recurrence during adjuvant targeted therapy. The blood-based biomarker outperforms traditional prognostic indicators including tumor mutational burden and interferon gamma gene expression. METHODOLOGY: Cell-free ctDNA is an…

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Culina Health partners with Adventist HealthCare Physician Alliance

, 2025-04-15 21:15:00 Culina Health, a digital platform offering clinical nutrition care, is partnering with Adventist HealthCare Physician Alliance to give the clinically integrated network’s members access to Culina’s registered dietitians.  New Jersey-based Culina Health connects individuals online to registered dietitians, who can provide coaching and tailor a care plan around a person’s weight loss…

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Medicaid expansion improves timely lung cancer treatment and access to high-volume hospitals

, 2025-04-15 21:16:00 Credit: Pixabay/CC0 Public Domain A new study published in The Annals of Thoracic Surgery suggests that Medicaid expansion under the Affordable Care Act has significantly improved access to timely treatment and high-volume hospitals for patients with early-stage non-small cell lung cancer (NSCLC). These findings underscore the critical role of health care policy…

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Study reveals a novel link between body fat and anxiety

, 2025-04-15 17:01:00 In a groundbreaking study, researchers at McMaster University have revealed a novel link between body fat (adipose tissue) and anxiety, shedding light on the intricate relationship between metabolism and mental health. The findings, published in the prestigious journal Nature Metabolism on April 15, 2025, are particularly relevant given the rising rates of…

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Software-as-Treatment Startup Click Therapeutics Gets FDA Authorization for Migraine Mobile App

Frank Vinluan , 2025-04-15 19:02:00 Drugs have been the standard migraine treatment for decades. The severe headaches, nausea, and other problems associated with this common disorder now have a digital treatment option, a mobile app developed by prescription digital medicines developer Click Therapeutics. The FDA marketing authorization announced Tuesday permits use of the Click digital…

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General Practioner, General Medical Services Scheme

brendan , 2025-04-15 11:35:00 HSE Dublin and North East has the following opportunity: General Practioner, General Medical Services Scheme Panel size approx. 1100-1200 (subject to variation) Ref: MN012025 Location: Monaghan Town, Co Monaghan Application Details Informal Enquiries : Fiona Monahan, GP Services Manager, Fiona.monahan2@hse.ie ph : 087 2580275 Closing Date : 12pm on Friday  09/05/2025…

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Click Therapeutics granted FDA market authorization for digital migraine drug

, 2025-04-15 19:34:00 Digital therapeutic company Click Therapeutics was granted FDA marketing authorization for its prescription digital therapeutic for the preventive treatment of episodic migraines. The de novo classification is for the company’s CT-132 offering, which it received FDA Breakthrough Device Designation for in 2022. CT-132 is intended for the preventive treatment of episodic migraine…

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RFK Jr. plans changes to vaccine injury reporting system

Daniel Payne , 2025-04-15 17:18:00 WASHINGTON — Health secretary Robert F. Kennedy Jr. said Tuesday that he plans to roll out changes to the vaccine injury monitoring system that would automate and increase data collection as well as look for negative impacts of the shots.  Reforming the current Vaccine Adverse Event Reporting System has long…

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Induction chemotherapy for nasopharyngeal carcinoma

Man Xu, Shuting Yang, Erying Cui, Zheng Wang, Xuqi Li , 2025-04-15 09:52:00 Man Xu, associated professor1 2, Shuting Yang, doctor1 3, Erying Cui4, Zheng Wang, professor3, Xuqi Li, professor1 1Department of General Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China 2Department of Radiation Oncology, Xi’an Gaoxin Hospital, Xi’an, Shaanxi,…

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Inflammation may be the link between chronic pain and depression

, 2025-04-15 18:46:00 Overview of study workflow. Credit: Science Advances (2025). DOI: 10.1126/sciadv.adt1083 Chronic pain—or pain that lasts at least three months—is closely intertwined with depression. Individuals living with pain’s persistent symptoms may be up to four times more likely to experience depression, research shows. Almost 30% of people worldwide suffer from a chronic pain…

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Researchers analyze the mutational landscape of TMB-high colorectal cancer tumors

, 2025-04-15 17:09:00 Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer-related deaths worldwide. The mutational landscape of CRC is well characterized, revealing key pathogenic genetic abnormalities that drive carcinogenesis (cancer development) and disease progression. Moreover, a step-wise colorectal carcinogenesis model has…

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Novel Agent Shows Promise in Early Parkinson’s Disease

, 2025-04-15 17:06:00 SAN DIEGO — Tavapadon, a novel and highly selective partial agonist of dopamine D1 and D5 receptors, significantly improved motor function without increasing impulse control disorders in patients with early Parkinson’s disease (PD), results of two separate phase 3 studies showed. The findings reflect outcomes from both fixed daily doses of 5…

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The Top-Rated Orthopedic Surgery Centers in the Houston Area and Beyond

Luidgi Faubert , 2025-04-15 13:20:00 Whether you’re a healthcare professional seeking reliable providers or someone exploring options for surgical procedures, finding the best orthopedic care is crucial for achieving optimal outcomes. These centers stand out as the top-rated orthopedic surgery centers in Houston for their advanced treatments, patient care and reputation within the medical community….

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6 Ways of Providing Better Patient Care

MNB Guest , 2025-04-15 14:53:00 A career in healthcare is not just about diagnoses and medication. Recently, we started merging different fields like psychology, education, and technology with a dash of soft skills with healthcare, and the results came out to be astounding! This was the answer that we have been searching for – to…

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