Research led by Professor Takami Tomiyama of Osaka Metropolitan University has shown that administering dried seeds of the jujube plant can restore cognitive and motor function in model mice with various forms of dementia. The study suggests that traditional medicinal products, like the jujube seeds used in Chinese medicine, could offer preventive measures against neurodegenerative…
Patient travel patterns for accessing specialty care often differ from traditional geographic boundaries like hospital service areas (HSA) or zip codes. A study analyzed data from the Medical Expenditure Panel Survey from 2018 to 2021 to assess the accuracy of these boundaries in capturing patient populations. It found that primary care service areas and HSAs…
Depression treatment often combines medication and therapy, but concerns about side effects and limited effectiveness of drugs deter many from seeking help. Researchers have identified a drug-free therapy, bright light therapy (BLT), as an effective adjunctive treatment for non-seasonal depressive disorder. A recent study found that BLT helped achieve symptom remission in 40% of cases….
Employers prioritize mental and physical wellbeing programs, but employees are more concerned about financial wellbeing support, according to a recent survey by WTW. While 73% of employers focus on mental wellbeing and 50% on physical wellbeing, 66% of employees see financial wellbeing as their main concern. This misalignment indicates a need for employers to reassess…
En los más de 600 hospitales católicos en Estados Unidos, no hay monjas ocupando cargos ejecutivos. Aunque las monjas fundaron y dirigieron estos hospitales con la misión de atender a los enfermos y pobres, con el tiempo se han convertido en grandes corporaciones que operan con fines de lucro. A pesar de que siguen reglas…
Biogen Inc. and Neomorph Inc. have entered into a partnership to develop molecular glue degraders for Alzheimer’s disease and other neurologic conditions. Biogen aims to use Neomorph’s discovery platform to accelerate the identification and validation of small molecule degraders that can remove harmful proteins associated with disease pathology. The partnership will focus on identifying, validating,…
Three independent pharmacies have filed lawsuits against GoodRx, accusing the company of colluding with pharmacy benefit managers to fix reimbursement fees, impacting the profitability of independent pharmacies. The lawsuit claims that GoodRx and PBMs coordinate their reimbursement policies to reduce fees for pharmacies, leading to financial struggles for many independent pharmacies. The dispute highlights the…
The UK government plans to ban smoking outside schools and hospitals as part of the Tobacco and Vapes Bill, aiming to create a smokefree generation by 2009. However, there is still a need for more investment in NHS stop smoking services. The bill will also make it illegal to sell tobacco to those born after…
Doctors have warned about “petticoat cancer,” a type of malignancy related to a tightly tied waist cord of the underskirt traditionally worn under a saree in rural parts of India. This condition, also known as “saree cancer,” can lead to chronic inflammation, ulceration, and even progression to skin cancer. The pressure and friction on the…
A study has identified a new curcumin derivative, C210, that selectively reactivates the Epstein–Barr virus (EBV) lytic cycle by inhibiting heat shock protein 90 (HSP90), leading to cancer cell death. The traditional EBV lytic induction therapy has shortcomings like low efficacy and infectious virion production, which C210 addresses. C210 disrupts HSP90 function, inducing EBV lytic…
Diabetes affects millions of people worldwide and can lead to serious health complications. Insulin plays a vital role in managing blood sugar levels, and when the body does not produce enough insulin, diabetes can develop. A healthy diet, exercise, and medication are crucial for managing diabetes and reducing complications. Diets rich in whole grains, fruits,…
Beam Therapeutics is developing a gene-editing therapy called BEAM-101 for sickle cell disease using base-editing technology. The therapy aims to increase the production of functional hemoglobin and improve the shape of red blood cells. Early results from the Phase 1/2 study show promising outcomes in patients, with increased levels of fetal hemoglobin and fewer sickle-shaped…
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The article emphasizes the importance of foot health and the role of podiatrists in specialized foot care. It highlights red flags that may indicate the need for podiatric care, such as persistent foot pain, changes in foot structure, diabetes-related foot complications, numbness, swelling, and changes in gait. Prompt evaluation by a podiatrist can help diagnose…
Durante la práctica de porristas en abril, la hija de Jana Duey, Karter, sufrió una conmoción cerebral. A pesar de días con dolor de cabeza y mareos, Karter recuperó con terapia física y apoyo escolar. Expertos enfatizan la importancia de un regreso gradual a la actividad física y escolar. Colorado actualizó sus directrices para manejar…
Obesity is a complex chronic disease that negatively impacts health, including musculoskeletal health. Excess weight affects joint function, leading to conditions like arthritis and low back pain. Biomechanical stress and chronic inflammation caused by obesity contribute to musculoskeletal complications, limiting mobility and increasing the risk of orthopedic surgery complications. Addressing weight management, physical activity, and…
STAT’s free newsletter Morning Rounds provides daily health and medicine updates. On Election Day, consider supporting STAT’s journalism with a 40% off subscription. The current election cycle has not seen many policy ideas, making it challenging for reporters to interpret candidates’ proposals. Screen time in children under two is linked to a higher risk of…
Two more cases of clade Ib mpox have been found in the UK, bringing the total to three. The patients are receiving treatment in London. Health officials are closely monitoring contacts and offering testing and vaccination. The risk to the population is considered low. Source link
A study published in Diabetologia found that overnight eating may increase the risk of chronic health conditions for night shift workers. The study involved 55 adults who were divided into groups based on their eating habits during night shifts. Participants who ate meals or snacks during the night had worse glucose tolerance compared to those…
A new publication in Acta Materia Medica journal explores the efficacy of Herba Siegesbeckiae (HS) in managing cardio- and cerebro-vascular diseases, particularly in ameliorating myocardial ischemia/reperfusion (I/R) injury. The study focuses on the interaction between UCHL5 and NLRP3 in the pathogenesis of I/R and identifies HS-C as the most effective subfraction in protecting against I/R…
Only 12% of nurses in hospitals and health clinics are men, despite increased representation since 1970. Stereotypes discourage men from entering the field, but efforts are being made to attract and support male nurses. Nursing schools are increasing outreach to men and promoting diversity in the profession. Highlighting nursing specialties, showcasing male nurses in marketing,…
Skipping breakfast is associated with a higher risk of being overweight, according to recent research in the Journal of Dairy Science. A specific breakfast choice, a dairy-based high-protein meal, was found to boost focus and keep individuals satisfied throughout the day. The study compared the effects of different breakfast choices on satiety, concentration, and daily…
Burnout among healthcare professionals, including clinicians and staff, remains a significant issue with implications for patient care, staff retention, and financial health of organizations. Factors contributing to burnout include long hours, patient demands, and administrative tasks. AI-driven automation is being used to alleviate this burden by streamlining documentation, scheduling, and routine tasks. Real-world results show…
The Medical Council opened 353 complaints in 2023, with 61 referred to its fitness-to-practice committee. A new service called CAREhub has been launched to provide mental health support and guidance to medical students, doctors, and the public engaging with the council’s regulatory processes. The service aims to support individuals through education, training, complaints, investigations, and…
A study found that over 54% of patients with rheumatic and musculoskeletal diseases use daily over-the-counter supplements, often alongside pain relievers, posing a risk for dangerous drug interactions. The researchers surveyed patients in England and found that the most commonly used supplements were vitamin D, multivitamins, and vitamin C. There was considerable overlap between the…
In a viral TikTok, a woman questions why many women in their 30s struggle with cancer and infertility, blaming birth control for hormonal disruption. Influencers on platforms like TikTok and YouTube mock birth control side effects and promote discontinuation, spreading misinformation. Studies show influencers’ impact on women’s choices and advocate for evidence-based information dissemination. Social…
The Commonwealth Fund report highlights the significant impact of gun violence in the US, identifying it as the leading cause of death among children and teenagers. The study also reveals that gun violence drives down life expectancy and costs the economy around $557 billion in 2022. Utilizing data from the Institute for Health Metrics and…
A study by researchers at Oregon Health & Science University found that Medicaid waivers provided for addiction treatment in large residential facilities did not lead to increased treatment or decreased nonfatal overdoses. These waivers were implemented in response to the opioid crisis, but the study found no overall benefit in the states that received them….
AIRE, an advanced AI platform, predicts heart disease risk and mortality accurately by analyzing patient data. A novel AI-enhanced electrocardiography (ECG) model called AIRE was developed and validated to predict mortality and cardiovascular risk. The model surpasses previous AI limitations and provides actionable insights for clinicians. It accurately predicts all-cause mortality, heart disease risks, and…
Europe is facing a shortage of general neurologists, which could have serious consequences for patient care. The European Academy of Neurology (EAN) has warned of increasing burdens of neurological disorders due to insufficient neurological workforce numbers. General neurologists play a crucial role in providing timely and comprehensive care for patients with neurological disorders. While some…
A recent study suggests that just 20 minutes of moderate daily exercise may not be enough to reduce the heart disease risk and signs of aging linked to prolonged sedentary time. The study found that adults spend 9 to 16 hours per day sitting, and even those who exercised at recommended levels faced a risk…
The HLTH conference featured companies showcasing their strengths and innovations in healthcare. Brook Health focuses on using AI for chronic disease management, claiming to have the best retention program. Carrum Health partners with health systems to provide value-based care programs, including one for substance use disorder. Genialis specializes in developing AI-driven biomarkers for precision medicine,…
The FDA has amended its Risk Evaluation and Mitigation Strategy for opioid analgesics to require manufacturers to provide prepaid mail-back envelopes to outpatient pharmacies and other dispensers. This change aims to facilitate the return of unused opioids and educate patients on safe disposal methods. In addition to the envelopes, manufacturers must update the drug’s Patient…
Private Medicare insurers are targeting veterans with Medicare Advantage plans that offer additional benefits like dental and vision. These plans are gaining popularity among veterans, with almost 42% enrolled in them in 2022. Health policy researchers are concerned about the growth of these plans because Medicare pays them a fixed monthly rate per enrollee, leading…
NHS England has launched a new campaign urging people to dial 999 immediately when stroke symptoms occur, as data reveals a nearly 90-minute average delay in calling for help. With 100,000 strokes and 38,000 related deaths in the UK each year, stroke is the fourth leading cause of death. The Act FAST campaign, initiated in…
Scientists are exploring the potential of repurposing the anti-malarial drug hydroxychloroquine to fight cancer, despite disappointing clinical trial results. Research from the Medical University of South Carolina’s Hollings Cancer Center found that cancer cells develop resistance to hydroxychloroquine not through expected pathways, but by changes in metabolism, division, and export. This discovery opens the door…
A study on the human sense of touch identified 16 different types of nerve cells, with comparisons to mice and macaques showing both similarities and differences. The research, published in Nature Neuroscience, aims to understand the complexity of bodily sensations beyond the traditional view of specific nerve cells for each type of feeling. Gene expression…
The study by Chen et al. investigated the long-term effects of ambient air pollution on the risk of lung cancer using data from four administrative cohorts. The study found a significant association between exposure to air pollution and increased incidence and mortality from lung cancer. This suggests that prolonged exposure to ambient air pollution may…
Research has revealed a sex-specific link between obstructive sleep apnea and the risk of developing dementia, particularly in older women. The study included 18,815 U.S. adults aged 50 and older who were initially dementia-free and followed for 10 years. Results showed that women with obstructive sleep apnea had a higher incidence of dementia than men…
The healthcare industry is experiencing point solution fatigue, leading to questions about the continued relevance of these solutions. Doba Parushev of Healthworx believes that while point solutions may work for certain conditions like musculoskeletal issues, they may not be suitable for complex conditions with multiple comorbidities. He predicts that in 2025, there will be fewer…
The global Medicines Safety Week campaign is encouraging people to report suspected side effects of medicines. The campaign involves medicines regulators from 107 organizations across 94 countries and emphasizes the importance of using medicines correctly to prevent side effects. Patients are reminded to read the package leaflet and take medicine as instructed by a healthcare…
OpenBiome has suspended its distribution of investigational fecal microbiota transplantation due to FDA guidance. This may impact patients with recurrent C. difficile infections. The FDA’s new policy no longer extends to stool banks, leading to concerns about access to FMT for severe cases. The AGA and other organizations have urged the FDA to reconsider and…
A potential second Trump presidency could lead to significant changes in healthcare access and costs, with uncertainty about his specific plans. Democrats have criticized a conservative think tank’s Project 2025 agenda, which Trump has not explicitly endorsed. Focus on this proposal has overshadowed Trump’s own statements on priorities like abortion, addiction policy, and insurance coverage….
Last week, the chancellor of the exchequer announced a budget that includes £22.6bn of extra funding for the NHS over the next two years, to be funded partially by raising employers’ national insurance contributions. This tax increase, from 13.8% to 15%, will disproportionately affect GP surgeries, social care providers, and hospices, who must absorb the…
A study found that individuals with a history of upper respiratory infections (URI) have an increased risk of developing Meniere disease (MD). Using data from the Korean National Health Insurance Service-National Sample Cohort, researchers discovered that the likelihood of developing MD was 2.01 times higher for individuals with a URI within one year of the…
Researchers at UC San Francisco have found that the keto diet can help alleviate symptoms of multiple sclerosis (MS) by producing compounds that affect the gut microbiome and the immune system in mice. By restricting carbohydrates and increasing fat consumption, the diet leads to the production of ketone bodies, which can reduce inflammation in MS….
A new analysis of the SELECT trial has shown that treatment with once-weekly semaglutide 2.4 mg significantly reduced hospital admissions for all causes, not just cardiac-related, in people with overweight/obesity and established cardiovascular disease. Semaglutide also reduced overall hospitalization time. The study found that those treated with semaglutide were less likely to be hospitalized for…
Researchers have found an optimal time frame for scheduling surgeries after a heart attack to reduce complications. Delaying elective surgeries for elderly cardiac patients who had a heart attack can decrease the risk of life-threatening complications such as heart attacks and strokes. Current guidelines recommend waiting two months before elective surgeries, but new research suggests…
Radiologists understand the importance of cybersecurity in their day-to-day imaging work, despite not being experts in security threats. Data breaches and downtime can create chaos for hospitals, IT teams, and patients, highlighting the need for effective security measures. Many practices and providers are slow to adopt cutting-edge security technology, putting healthcare data at risk. Radiologists…
New research aims to create a quantitative measure for hyper-palatable foods, which target reward pathways in the brain. Food manufacturers are exploiting our hedonism with ultra-processed foods high in fats, sugars, and sodium. A study identified three key taste clusters in hyper-palatable foods and found that over 60% of food items in a USDA database…