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US Supreme Court decision on challenge to mifeprostone

The US Supreme Court case involved pro-life medical associations and doctors seeking to rescind FDA approval of the drug mifepristone, used in abortion. The FDA initially approved the drug in 2000 with restrictions, which were relaxed in 2016 and 2021. The plaintiffs argued against the FDA’s actions, but the Court ruled they lacked standing due…

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Desktop system for calculating UV eye damage goes mobile

Australia has high levels of UV radiation, leading to an increased risk of skin cancer and eye diseases. One Australian is diagnosed with melanoma every 30 minutes, emphasizing the importance of early detection. Solutions include questionnaires for sun-safe behavior, UV-sensing wearable devices, and a desktop system to assess UV damage to eyes. Researchers are working…

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Meet the Middleman’s Middleman – KFF Health News

Many people are being hit with unexpected bills due to their health insurance not covering out-of-network care fully. A little-known data firm called MultiPlan is working with insurance companies to suggest cuts to coverage, leaving patients to pay the difference. New York Times reporter Chris Hamby investigated MultiPlan’s practices, revealing how they make money and…

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‘Proof of concept’ established for FcRn receptor blocker nipocalimab in Sjogren’s disease

A study presented at the EULAR 2024 Congress showed that treatment with nipocalimab, a neonatal Fc receptor blocker, led to significant improvement in patients with Sjögren’s disease compared to placebo at week 24. Nipocalimab targets the underlying causes of Sjögren’s disease by lowering levels of immunoglobulin G autoantibodies. The study included 163 patients, with the…

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Should Doctors Address Dying Patients’ Spiritual Needs?

Addressing patients’ spiritual needs is crucial for their overall well-being, especially in palliative care settings. However, doctors and nurses often lack the time and knowledge to provide spiritual care. A training program called SpECi aims to help healthcare professionals better perceive and meet the spiritual needs of seriously ill patients. The program has shown success…

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It’s Called an Urgent Care Emergency Center — But Which Is It?

Tieqiao Zhang experienced severe stomach pain, later diagnosed as a kidney stone, and visited Parkland Health’s Urgent Care Emergency Center near his home in Dallas. The center, operating as a freestanding emergency department, charged him $19,543 for two visits, despite being insured by BlueCross and BlueShield of Texas. Zhang faced difficulties in navigating the differences…

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Isatuximab-VRd more effective in treating older patients with multiple myeloma

Dr. Adam Cohen discussed the role of quadruplet induction regimens for transplant-ineligible patients with multiple myeloma at the ASCO Annual Meeting. The IMROZ and BENEFIT trials showed that the combination of isatuximab with bortezomib, lenalidomide, and dexamethasone was more effective for newly diagnosed older patients than the standard treatment option. This suggests that quadruplet regimens…

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European countries differ in their drinking styles, study finds

A study of drinking patterns in Europe from 2000 to 2019 identified six distinct clusters based on alcohol consumption. The clusters included wine-drinking countries, high beer/low spirit drinking countries, high beer/binge drinking countries, high spirit drinking countries, high spirit drinking/high lifetime abstinence countries, and countries with high prevalence of current and binge drinking. These patterns…

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Family history of mental health disorders linked to developmental outcomes in siblings of autistic children

A recent study in the journal Autism Research examined how family history of neurodevelopmental and neuropsychiatric disorders impacts the developmental outcomes of younger siblings of children with autism. The study found that siblings with a family history of anxiety, depression, schizophrenia, bipolar disorders, and intellectual disabilities had different phenotypic outcomes. For example, anxiety disorders were…

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Semaglutide Equally Effective in Women With HFpEF, Obesity

Women with heart failure with preserved ejection fraction (HFpEF) and obesity, with or without diabetes, show benefits from the GLP-1 receptor agonist semaglutide just like men do. The study analyzed trials comparing semaglutide with a placebo on over 1,000 participants, with similar benefits for both sexes. Women lost more weight but had similar improvements in…

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Who Is Responsible for the High Cost of Prescription Drugs? One Advocate Weighs In

About 28% of American adults struggle to afford prescription drugs, with the U.S. spending more on medications than other countries. Merith Basey of Patients for Affordable Drugs blames pharmaceutical companies for maintaining monopolies with patents and preventing Medicare from negotiating drug prices. Meanwhile, Pharmaceutical Research and Manufacturers of America (PhRMA) claims pharmacy benefit managers (PBMs)…

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Employer-focused Progyny acquires Berlin-based fertility benefits platform Apryl

Progyny, a publicly traded fertility and family building company, has acquired Berlin-based fertility benefits platform Apryl, expanding its global reach. Progyny offers benefits focusing on family building, fertility, and women’s reproductive health, including IVF, adoption, IUI, and surrogacy. Apryl allows companies to customize offerings for employees, providing guidance, fertility planning, reproductive technology, and adoption and…

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Young Gay Latinos See Rising Share of New HIV Cases, Leading to Call for Targeted Funding

Fernando Hermida sought asylum in the U.S. and was diagnosed with HIV in January 2022. Despite efforts to address the HIV epidemic, Latino communities are experiencing disproportionate rates of new infections and diagnoses. Latino health policy advocates call for more funding and targeted outreach to address the issue. Hermida struggled with navigating the healthcare system,…

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First generic GLP-1 receptor agonist launched

The first generic GLP-1 receptor agonist, liraglutide 1.8 mg, has been launched in the U.S. by Teva Pharmaceuticals. This medication is indicated for improving glycemic control in patients with type 2 diabetes and reducing the risk of cardiovascular events in certain patients. The brand-name version of this medication had annual sales of $1.656 billion. Common…

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Long covid: I’d rather have a well researched and well informed doctor than “become my own physician”

Karen L Hargrave, a freelance researcher and policy analyst based in London, UK, shares her experience of being diagnosed with long covid and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) along with her husband. She developed long covid in 2020 and her husband in 2022. While she is more functional with limitations on exertion, her husband is…

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Study uncovers multiple molecular subgroups in liver cancer with most aggressive driving clinical outcomes

A study led by researchers at the National Cancer Centre Singapore and A*STAR’s Genome Institute of Singapore has revealed unexpected molecular heterogeneity within liver tumors. More than 40% of hepatocellular carcinoma cases exhibit multiple molecular subtypes within the same tumor, with the most aggressive subtype predicting patient outcomes. This “bad apple effect” highlights the need…

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A new approach to treating diabetes

A recent study explores the important role of gut microbiota in the development and management of diabetes mellitus (DM), specifically type 2 diabetes (T2DM). The study found that T2DM patients had compositional changes in their gut microbiota, including lower levels of certain bacteria and increased presence of pathogens. Dysbiosis of the gut microbiome can impact…

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High Recurrence in Acute Uveitis Linked to Viral Causes

A study conducted in New Zealand analyzed 2763 eyes of 2092 patients with acute anterior uveitis to understand the risk for recurrence and precipitants for relapse. Approximately half of the patients experienced recurrence in the same eye, with a quarter having recurrence in the other eye, particularly in cases linked to viral causes. The study…

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Study Identifies Intermittent Dieting Plan To Improve Glycemic Control In Diabetic Patients

Intermittent fasting, such as the 5:2 technique combined with meal replacements, may help individuals with type 2 diabetes manage their blood sugar levels. A study involving 405 obese or overweight adults in China found that participants following the 5:2 meal replacement plan experienced better glycemic control, weight loss, and reduced waist and hip circumference compared…

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Unraveling Healthcare Innovation Spend: Where Healthtech Founders Need to Focus

The U.S. healthcare system is facing financial challenges post-2020, with a need to balance patient outcomes with financial health. Health systems are focusing on staff management, operational efficiency, and increased access to care as areas for innovation. Solutions like nurse marketplaces, staff development investments, and AI for operational efficiency are gaining traction. Improved access to…

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Re-evaluating The Risks Associated With Saturated Fats

The Dietary Guidelines for America recommend limiting saturated fat to less than 10% of total calories, based on the outdated diet-lipid-heart hypothesis that saturated fats cause heart disease. However, recent scientific studies have shown that saturated fats do not increase the risk of heart disease. The hypothesis was initially proposed by Ancel Keys in the…

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Mobile face screening tool detects stroke ‘in seconds’

Biomedical engineers at RMIT University and São Paulo State University have developed an AI-powered smartphone feature to screen patients for stroke by analyzing facial symmetry and muscle movements. The tool achieved 82% accuracy in detecting stroke in seconds and researchers are now seeking collaborations to turn it into a mobile application. This innovation addresses the…

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Jóvenes latinos gay ven un porcentaje cada vez mayor de nuevos casos de VIH; piden financiación específica

Fernando Hermida, un inmigrante que buscó asilo en Estados Unidos, fue diagnosticado con VIH a los 31 años después de luchar por encontrar atención médica adecuada. A pesar de los esfuerzos federales para acabar con la epidemia de VIH en el país, los latinos siguen experimentando tasas desproporcionadamente altas de infecciones y diagnósticos. Se enfrentan…

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ASCO guideline helps clinicians address cannabis use ‘head on’ with their patients

The increased accessibility of cannabis and cannabinoids has created challenges for clinicians treating cancer patients, as many patients are turning to these products for symptom relief or cancer treatment without sufficient evidence. An ASCO guideline provides recommendations for the medical use of cannabis and cannabinoids in adults with cancer. The lack of scientific evidence is…

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USDA secretary urges farmers to take protective measures

The H5N1 avian flu outbreak in dairy herds is approaching the three-month mark, prompting the U.S. Department of Agriculture to emphasize the importance of biosecurity measures in containing the virus. Despite resources and support from the USDA, uptake has been low, with only four herds participating in a voluntary testing pilot program. The virus has…

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More African nations focus on HPV vaccination against cervical cancer, but hesitancy remains

African countries are working to vaccinate more young girls against the human papillomavirus (HPV) to reduce rates of cervical cancer, which is high in the region. However, misinformation and vaccine hesitancy, fueled by rumors and religious beliefs, pose challenges. Despite efforts by health workers, only a few countries have reached the 90% coverage goal. Limited…

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Six Subtypes of Depression, Anxiety Identified Via MRI

Brain imaging combined with artificial intelligence has identified six unique “biotypes” of depression and anxiety, leading to more personalized and effective treatment. This research has immediate clinical implications, with plans to make the technology accessible to more clinicians and patients. The study, published in Nature Medicine, found that these biotypes predict response to different interventions,…

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Know Signs For Early Detection

Penis cancer cases are on the rise globally, with a predicted 77% increase in the next three decades. A study by researchers in China analyzed data from 44 populations in 43 countries from 1973 to 2012, revealing an estimated 36,068 new cases and 13,211 deaths per 100,000 cases in 2020. Incidence is increasing in 15…

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NeuroFlow Acquires 2nd Behavioral Health Company in 1 Year

Behavioral health companies are consolidating to meet the rising demand for mental health services. NeuroFlow, a behavioral health software startup, recently acquired Owl, a provider of measurement-based behavioral health care. NeuroFlow’s platform allows providers to assess patients’ mental health, engage with personalized self-care activities, and measure progress. The acquisition of Owl will expand NeuroFlow’s reach…

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Asian gastro docs generally trust and accept AI: survey

A recent international study conducted by Nanyang Technological University Singapore looked at the perceptions of 165 gastroenterologists and gastrointestinal surgeons from Singapore, China, Hong Kong, and Taiwan regarding the use of AI in healthcare. The research found that around 80% trust and accept AI in diagnosing and assessing colorectal polyps, while about 70% trust AI…

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CGM metrics predict risk for stage 3 type 1 diabetes better than patient characteristics

Continuous glucose monitoring (CGM) metrics can predict imminent stage 3 type 1 diabetes for individuals who are islet autoantibody positive. A study compared predictive models using data from five study groups and found that CGM metrics alone outperformed baseline characteristics for predicting type 1 diabetes risk. Combining patient characteristics with CGM metrics provided the best…

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Kaiser’s Risant Health to add Cone Health

Kaiser Permanente announced the acquisition of Cone Health in North Carolina, expanding its Risant Health network. Cone Health includes four acute-care hospitals, over 700 doctors, an accountable care organization, and a health plan. The terms of the deal were not disclosed, and neither Kaiser nor Cone provided immediate comments. This move will further strengthen Kaiser…

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Growth factors linked to stem cell aging in bone marrow study

A study conducted at the Jackson Laboratory focused on hematopoietic stem cells in the bone marrow of middle-aged mice, revealing variations in cell aging among individuals. The research found that the decline in growth factors produced by surrounding mesenchymal stromal cells correlated with age-associated changes in stem cells. This study, which looked at individual mice…

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Fixed-Ratio Insulin Combinations May Reduce Side Effects

Using fixed-ratio insulin combinations (FRC) can reduce side effects in treating diabetes, making clinicians more willing to consider these drugs. Dr. Liana K. Billings presented at the ADA 84th Scientific Sessions, highlighting the advantages of FRC, such as reduced nausea and increased convenience for patients. Studies show FRCs like insulin degludec/liraglutide (IDegLira) have lower rates…

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Roche Adds Another Neuro Alliance, Inking R&D Pact With RNA-Editing Startup Ascidian

Roche has partnered with Ascidian Therapeutics, a startup focused on editing RNA to address mutations driving diseases. Ascidian’s technology edits RNA exons to potentially solve issues in devastating diseases. Unlike traditional gene editing, Ascidian’s approach focuses on protein-coding segments of RNA to replace mutated exons with functional ones. This avoids immune responses and off-target edits….

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Annexon previews emerging data on ANX007 for geographic atrophy

Lori Taylor of Annexon Biosciences presented data on ANX007 for the treatment of geographic atrophy at Clinical Trials at the Summit in Park City, Utah. The data focus on the preservation of photoreceptors and retinal pigment epithelial cells in the foveal center, potentially explaining the visual acuity benefit seen with ANX007. The presentation highlighted the…

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Six tips for staying safe

Extreme heat poses risks for people spending time outdoors, such as runners, workers, and children. It is essential to adjust activities to avoid the hottest part of the day, hydrate properly, listen to the body for warning signs of heat illness, choose appropriate clothing, and prioritize getting a good night’s sleep. Older adults and children…

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