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WeightWatchers combined with weight loss medications may alter alcohol consumption, study finds

A study by researchers at Henry Ford Health in collaboration with WeightWatchers International found that over 40% of individuals in a weight loss program who used popular weight loss medications decreased their alcohol consumption. Medications like bupropion and naltrexone were associated with the greatest reduction in alcohol use. However, adjusting for weight loss may have…

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Recovery periods important to maintain the health and well-being of medical professionals

A study examined the psychobiological responses of Pre-Hospital Emergency Medical doctors and paramedics during high-fidelity training scenarios over two weeks. The research found that emergency situations trigger stress responses that are essential for dealing with threats, but repeated exposure to emergencies can lead to burnout. The study highlights the importance of recovery periods for maintaining…

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Diet Matters in Prostate Cancer, but It’s Complicated

Recent studies have shown that diet plays a role in prostate cancer risk and progression. Diets like ultralow-carbohydrate, weight loss, omega-3 fatty acid supplementation, and pro- and anti-inflammatory diets have been linked to affecting prostate cancer risk. Studies have shown that diets adhering to the US government’s recommendations and plant-based diets may lower the risk…

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Enhancing the efficacy of cell transplantation therapy for stroke or traumatic brain injury

Researchers have developed a technique to improve cell transplantation therapy for stroke or traumatic brain injury by using human induced pluripotent stem cell-derived brain organoids. The study, published in Stem Cells Translational Medicine, found that treatment with the growth factor progranulin enhanced the survival and engraftment of transplanted neurons. This priming agent improved axonal extension…

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KIT’s 3ROCKIT 3R Center works towards developing methods to replace animal testing

3ROCKIT is a center at KIT that focuses on replacing animal testing with digital and technological solutions in healthcare. It follows a 6R principle to reduce, replace, refine, ensure robust experimental designs, register experiments, and publish negative results. Using AI and digital technologies, researchers create Virtual Human Twins for personalized medicine, simulate active ingredients and…

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Debate Continues Over Prolonged Grief Disorder

Prolonged grief disorder (PGD) was added to the DSM-5-TR two years ago, sparking debate over pathologizing grief and setting specific timelines. PGD is characterized by intense and disabling yearning for a deceased person lasting over a year, requiring evaluation to prevent distress, poor health, and suicide. PGD diagnosis involves specific symptoms persisting for a month,…

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New report urges guidelines for stem cell-based embryo models

The Nuffield Council on Bioethics in the UK recommends setting guidelines for stem cell research that mimics aspects of embryonic development. They suggest not using these models to start pregnancies or making them capable of feeling pain or awareness. Current models are not advanced enough for these outcomes, but researchers are continuously improving them. The…

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Asthma: New UK guidelines signal “step change” in diagnosis and treatment

The new clinical guidelines recommend that combination treatment with an inhaled corticosteroid and formoterol should be the standard first-line treatment for asthma patients aged 12 and over, rather than prescribing short-acting β2 agonists like salbutamol alone. This approach, known as anti-inflammatory reliever therapy, aims to reduce inflammation and relieve symptoms to prevent hospital admissions and…

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Africa’s making progress against HIV, but donor funds are drying up—what must change

Significant progress has been made in the fight against the HIV epidemic in the last two decades, particularly in Africa where access to treatment has increased and HIV-related deaths have declined. However, there is a lack of momentum globally, threatening the strides made. Challenges include dwindling funding, particularly in Sub-Saharan Africa, where most HIV cases…

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COP29 outcomes fall short on climate health action

Experts from LSHTM found that agreements made at COP29 did not fully address the impacts of climate change on health. While progress was made in integrating health into the climate agenda, significant shortcomings remained. Richer countries agreed to provide $300 billion annually to poorer countries by 2035 to tackle climate change, falling short of the…

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Community Factors Linked to Increased MCI Risk

A study involving 2830 older adults found that greater neighborhood disadvantage, exposure to air pollution, higher homicide rates, and reduced greenspace are associated with an increased risk for mild cognitive impairment (MCI). Factors such as the Area Deprivation Index (ADI), fine particulate matter exposure, homicide rates, greenspace, and schooling location were linked to MCI. The…

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Synapticure Secures $25M To Scale Virtual Care for Neurodegenerative Diseases

Synapticure, a virtual care company focusing on neurodegenerative diseases, has raised $25 million in Series A funding to expand its services and partnerships. The Chicago-based company offers virtual access to neurologists, treatments, and care coordination services for diseases like Alzheimer’s, Parkinson’s, and ALS. The funding, led by B Capital, will be used to enhance AI-powered…

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Four-in-ten first-time HIV diagnoses found late

In 2023, there was a 15% decrease in new HIV diagnoses in Ireland compared to pre-pandemic years, with a total of 911 cases reported. However, almost 40% of cases were diagnosed late, with 61% of cases found in people already aware of their HIV status. The number of first-time diagnoses has been increasing since the…

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AI may help build website, but customization needed

In a Healio Video Perspective, Cynthia Matossian, MD, FACS, and David Evans, PhD, MBA, discuss the use of AI in building ophthalmology practice websites. Evans mentions that AI can make websites more intuitive and cost-effective, but lacks personalization. Matossian emphasizes the importance of customizing content to differentiate from competitors also using AI. The discussion highlights…

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Mpox: UK reports new case of clade Ib infection

A new case of clade Ib mpox has been found in England, with the patient being treated in Sheffield Teaching Hospitals NHS Foundation Trust after returning from Uganda. UK Health Security Agency (UKHSA) is monitoring the situation closely as Uganda is experiencing community transmission of this variant. The agency has not released any further details…

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3 reasons why kids stick Lego up their nose

Children, especially toddlers and preschoolers, have a natural curiosity that can lead them to stick small objects up their nose. Queensland Children’s Hospital reported over 1,650 cases of foreign objects being stuck in children’s noses over the past decade. Reasons for this behavior include curiosity-based learning, imitation of adults and older children, and a limited…

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Updated Lupus Nephritis Guideline Advises Triple Therapy

The new guideline for managing lupus nephritis (LN) was presented at the ACR 2024 Annual Meeting, recommending a more aggressive first-line approach using triple therapy with glucocorticoids, mycophenolate or cyclophosphamide, and a newer agent like belimumab or voclosporin. The guideline emphasizes shared decision-making with patients, reducing healthcare disparities, and considering pediatric and geriatric populations. Recommendations…

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Common MRF Mistakes Hospitals Are Making in 2024

The CY 2024 OPPS Final Rule has led to hospitals adopting new schema for machine-readable files (MRFs). After reviewing numerous files, three common mistakes were identified that prevent hospitals from being compliant with CMS’ validator tool. These mistakes include incorrectly formatted TXT records, not using the “additional notes” column effectively, and underestimating the difficulty of…

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A truly tragic case

The England and Wales Court of Protection ruled on a case involving a young man who suffered a significant brain injury after a kidney and pancreas transplant. The man was receiving life-sustaining treatment in a rehabilitation unit, and his parents disagreed with the medical decisions being made. Despite the efforts of the Official Solicitor to…

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Trump taps biotech investor Jim O’Neill for HHS deputy secretary

President-elect Trump has nominated biotech investor Jim O’Neill for deputy secretary of the Health and Human Services department. O’Neill would oversee the day-to-day operations of sub-agencies running programs like Medicare and Medicaid, public health emergency preparedness, federal research, and more. He would also manage the development and clearance of HHS regulations, working under HHS secretary…

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Reaffirming our commitment to the NHS is needed now more than ever

The content discusses the recommendations for a new NHS strategy to address the acute response needed. It suggests a cash injection of £32 billion to tackle current crisis issues, including surgery backlogs and mental health. The strategic response focuses on removing barriers to healthcare, such as efficient resource allocation, investment in primary care, technology implementation,…

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Flexibility demands influence motor cortex’s involvement in execution of motor sequences, rat study finds

A recent study by researchers at Harvard University investigated the role of the motor cortex in executing motor sequences in rats. The study found that the involvement of the motor cortex depends on the flexibility required for the task. Rats trained on specific sequences without flexibility were unaffected when the motor cortex was lesioned, while…

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Warmer temperatures weaken immune systems in wild capuchin monkeys

A University of Michigan study found that the immune performance of wild capuchin monkeys declines in higher temperatures, particularly affecting younger monkeys. This decline in immune system function was observed after just two weeks of temperatures around 86 degrees Fahrenheit. The study, focusing on the immune biomarker neopterin in urine samples, highlighted the vulnerability of…

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Adalimumab Biosimilars Comparable With Originator

A study comparing the drug survival and safety of adalimumab biosimilars with Humira among new users found similar results. However, patients switching from Humira to biosimilars had a 35% higher discontinuation rate. The study included 7387 adalimumab-naive patients and 3654 switchers. All-cause drug discontinuation rates were similar between new users of biosimilars and Humira, but…

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Miscarrying Texas Mother Becomes Latest Woman to Die As Doctors Risk 99-Year Prison Sentence for Administering Life-Saving Drug

A Texas mother died due to the state’s abortion ban preventing a life-saving procedure. Porsha Ngumezi suffered a miscarriage at 11 weeks pregnant, losing blood. Despite needing a D&C, the doctor gave her misoprostol instead, resulting in her passing away. This is the fifth preventable death due to lack of access to D&Cs or dilation…

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FDA Nod for BridgeBio Brings New Competition to Blockbuster Pfizer Cardio Drug

BridgeBio Pharma’s drug, Attruby, has received FDA approval for treating cardiomyopathy caused by transthyretin-mediated amyloidosis (ATTR). The drug stabilizes the abnormal protein responsible for the disease, showing significant improvement in clinical trials. Attruby is positioned to compete with Pfizer’s tafamidis, a well-established treatment for ATTR. Other companies, like Alnylam Pharmaceuticals and partners AstraZeneca and Ionis…

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Voting is a con. Not voting is worse.

The writer argues that the idea of individual choice in elections in Ireland is diluted by the proportional representation system. Voters may be swayed by single issues or long-term goals that may not align with their best interests. Parties may promise action on issues like housing and healthcare, but political realities may prevent meaningful change….

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Cardiologist in charge of YouTube Health fights misinformation

YouTube plays a crucial role in providing health information to users, with a focus on removing dangerous misinformation and promoting high-quality, evidence-based content. Garth Graham, the global head of healthcare and public health at YouTube, emphasizes the platform’s responsibility in delivering accurate health information. YouTube Health aims to combat misinformation, support underserved communities, and protect…

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Covid-19 may raise risk of developing multiple sclerosis

New research from örebro University and örebro University Hospital in Sweden suggests that Covid-19 may be a risk factor for multiple sclerosis (MS). The study found a higher risk of MS among individuals who had severe Covid-19, with nearly 26 per 100,000 patients with serious Covid-19 subsequently developing MS. However, only a small number of…

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Sleep-Disordered Breathing Common After Stroke

A new study found that sleep-disordered breathing (SDB) affects 60% of stroke patients, with prevalence rates ranging from 57% in North America to 70% in Asia. The overall prevalence of SDB remained unchanged between 2010 and 2023. The study included more than 5.7 million patients with stroke from 26 countries. SDB was assessed using various…

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AI-Powered Insights for Personalized Customer Experiences: The Art of Data-Driven Engagement

The evolution of customer engagement in the pharmaceutical industry emphasizes the importance of translating data into personalized interactions. Synchronizing field engagements and digital promotions can boost campaign effectiveness, but many interactions remain unsynchronized. Healthcare providers value consistency and expect seamless interactions across multiple touchpoints. While AI and advanced analytics can predict engagement patterns, their true…

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RCPI Institute of Medicine Autumn Symposium

The RCPI Institute of Medicine held an Autumn Symposium on September 25, 2024, in Dublin. The event featured speakers such as Dr. Diarmuid O’Shea and Prof. Clare Fallon among others. The symposium aimed to discuss important medical issues and advancements in the field. Attendees included healthcare professionals and experts in the medical field. The event…

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