Dr. Ray O’Connor reviewed recent clinical papers on lung cancer, highlighting advances and challenges in treatment. Non-small cell lung cancer (NSCLC) accounts for the majority of cases and is typically treated with surgery, chemotherapy, or radiotherapy. Lifestyle factors like smoking, alcohol, and coffee intake can increase lung cancer risk, while tea intake may be protective….
Many schools are not implementing precautions against seasonal COVID-19, leading to more children experiencing multiple infections and increasing the risk of developing Long COVID. A study identified common symptoms of Long COVID in kids aged 6-17, showing that a significant proportion experience symptoms lasting more than four weeks after infection. Even asymptomatic children were found…
Este año, California ha ampliado el programa Medi-Cal para incluir a todos los residentes que cumplan con los requisitos, independientemente de su estatus migratorio. Esta expansión ha significado un aumento en el gasto del programa, que actualmente atiende a 15 millones de residentes de bajos ingresos, incluyendo aproximadamente 1.5 millones de inmigrantes indocumentados. Aunque la…
Children with multiple long-term conditions are at a significantly higher risk of death, hospitalization, and other severe outcomes after contracting COVID-19. A systematic review and meta-analysis of 111 studies revealed that these patients were more than twice as likely to die compared to those without multiple conditions. The risk was higher for hospitalization, ICU admission,…
Johnson & Johnson has filed a lawsuit against the U.S. Health Resources and Services Administration over a dispute regarding payment methods for hospitals in the federal drug discount program. The company argues that the agency has misinterpreted the federal law concerning rebates in the 340B Drug Pricing Program. Johnson & Johnson recently attempted to change…
GPs in a local area are facing a change where they will no longer be able to request MRI scans for patients with musculoskeletal symptoms. Instead, patients will be referred to a musculoskeletal clinical assessment and triage service (CATS) staffed by advanced practitioners. The goal is to reduce unnecessary imaging and streamline referrals for orthopaedic…
Recent research has focused on neuroglia, a group of brain cells that support neurons and may play a role in psychiatric illnesses like depression and schizophrenia. Previously overlooked, these cells have their own signaling system and are crucial for brain function. Understanding neuroglia could lead to better explanations for psychiatric symptoms and personalized treatments. Advances…
Portal vein thrombosis (PVT) is a challenging complication in liver cirrhosis without sensitive diagnostic markers. A study investigated neutrophil extracellular traps (NETs) and Deoxyribonuclease (DNase) as potential indicators for PVT in chronic hepatitis B (CHB)-related decompensated cirrhosis. They found PVT patients had high levels of cell-free DNA and histone-DNA complexes, with reduced DNase activity, regardless…
Modularity optimization (MO) is shown to provide better localization of emergency general surgery (EGS) care regions and hospital communities compared to traditional Dartmouth Health Referral Regions (HRRs). The study analyzed data from over 1.2 million adults with EGS conditions in California and New York, using the Louvain community detection method to identify regional EGS networks…
Pregnant women are advised to get vaccinated against respiratory syncytial virus (RSV) between 32 and 36 weeks of pregnancy to protect their newborns. Research suggests that getting vaccinated closer to 32 weeks provides the most efficient transfer of antibodies to the newborn. This can lead to higher and longer-lasting antibody levels in both mothers and…
The radioligand therapy (RLT) industry is evolving with major investments from pharmaceutical companies like Eli Lilly and Novartis. These investments are focused on research, manufacturing, and service capabilities to support the adoption of personalized cancer treatments. To succeed in this new landscape, companies must adopt a holistic service approach, prioritize customer centricity, build internal capabilities,…
The National Office of Clinical Audit (NOCA) reported an increase in the number of hip fracture patients being transferred out of the emergency department within four hours last year, with 29% receiving timely treatment compared to 21% the previous year. The Irish Hip Fracture Database (IHFD) also showed improvements in hip fracture care, with 75%…
The latest wellness trends are moving towards a natural, holistic approach, focusing on mindfulness, natural beauty treatments, outdoor activities, herbal remedies, and functional fitness. These trends aim to improve overall well-being and promote a healthier lifestyle. Mindfulness includes activities like breathwork and sound baths, while natural beauty treatments involve plant-based ingredients for skin care. Spending…
Californian authorities are facing an increase in locally acquired cases of dengue, a dangerous virus spread by Aedes mosquitoes. The Aedes mosquitoes are now present in at least 24 California counties, bringing the threat of not only dengue but also other tropical diseases like chikungunya, Zika, and yellow fever. Authorities are implementing surveillance, response plans,…
Hepatitis delta virus (HDV) is a less-known type of hepatitis that can be life-threatening. Many people only discover they have HDV when they receive a diagnosis, often at an advanced stage of the disease. The medical community is being urged to increase awareness and improve screening for HDV, as early detection can lead to better…
A new biotech company called Trace Neurosciences has been launched to develop a genetic treatment targeting the UNC13A gene linked to ALS. This new strategy has the potential to treat the majority of ALS patients, as well as those with other brain disorders. The company expects to begin testing its lead drug candidate in clinical…
has identified key principles and recommendations to guide funders in integrating sex and gender considerations into all stages of research. By incorporating these principles, research funders can support the advancement of gender-sensitive research and improve the quality and relevance of scientific studies. This framework is a significant step towards promoting diversity and inclusivity in research…
A new coating developed by University of British Columbia researchers could improve the safety of medical devices by reducing the risk of blood clotting. The coating mimics the behavior of blood vessels, preventing clot formation on devices like catheters, stents, and dialysis machines. This innovation could eliminate the need for high doses of blood thinners,…
A recent study on prenatal exposure to maternal SARS-CoV-2 infection found minor differences in infant regulatory behavior but no significant long-term effects on neurodevelopment. The study examined children up to two years of age and compared those exposed to SARS-CoV-2 in utero with a negative comparison group. Results showed slightly better attentional ability in exposed…
A recent analysis found that receiving radiotherapy after prostatectomy negatively affects long-term health-related quality of life, including sexual function, urinary incontinence, and urinary irritation. However, the timing of radiation after surgery, whether within a year or over a year, does not have a significant impact on patients’ quality of life over the long term. Delaying…
Good sleep is crucial for children’s behavior and attitude. A study found that consistent sleep schedules have a greater impact on emotional regulation and behavior than the duration or quality of sleep. Researchers tracked 143 six-year-old children’s sleep patterns and behavior, finding that those with consistent bedtimes showed better self-regulation and emotional control. Children with…
Microsoft has formed partnerships with various health systems to develop AI applications that can benefit clinicians. UW Health is focusing on AI applications to interpret medical images, while Providence is working on a machine learning model for digital pathology. Stanford Health Care is scaling up its use of Microsoft’s Dragon Ambient Experience listening tool to…
Root canals are no longer something to fear thanks to modern dental technology. More than 15 million teeth are saved each year with this procedure. It is important to follow post-procedure instructions to ensure a speedy recovery. Take pain medication as prescribed, rinse with warm salt water, and apply a cold compress to reduce swelling…
Deucravacitinib, a treatment for psoriatic arthritis, was found to be more effective compared to a placebo in improving response across all criteria for minimal disease activity in patients with PsA at 16 weeks. A phase 2 trial showed that deucravacitinib led to significant improvements in musculoskeletal manifestations, psoriasis, and overall physical/mental health, with around 24%…
Genetics startup 23andMe announced significant changes, including halting the development of new medicines, laying off 40% of its workforce, and focusing on selling genetic tests to consumers for research. The company decided to close its therapeutics division and lay off 200 employees, ending a decade-long bet to become a drug company using genetic data. The…
Child maltreatment, including physical, sexual, psychological, and neglect, is common and healthcare providers may encounter it in their practice. Recommendations for identifying and assessing child maltreatment in primary care and emergency settings include performing thorough examinations, asking appropriate questions, and limiting physical assessments for suspected sexual abuse. Clear and objective documentation, using quotations, drawings, and…
New research suggests that getting the respiratory syncytial virus (RSV) vaccine earlier in pregnancy, closer to 32 weeks, provides the best protection for newborns against RSV. Maternal vaccination at least 5 weeks before delivery leads to more efficient transfer of antibodies to the newborn. The study found that RSV antibody levels were higher and longer-lasting…
A team at Mount Sinai developed a deep learning algorithm to monitor infant movements in the NICU, providing real-time insights into neurological health. This AI tool could revolutionize neurologic monitoring in NICUs and detect changes early for faster interventions. The team trained the algorithm on video data from 115 infants in the NICU and found…
The EARLY TAVR study showed that transcatheter aortic valve replacement (TAVR) is superior to surveillance in patients with severe but asymptomatic aortic stenosis. The study, conducted in the US and Canada, involved 901 patients with no symptoms of aortic stenosis. Results indicated a 50% lower risk of death, stroke, and hospitalization in the TAVR group…
Maternal mental health conditions are common during pregnancy and the postpartum period, with a significant economic cost of $14 billion annually. Efforts are being made to improve care for mothers, such as the MCPAP for Moms program, which helps providers address mental health issues in pregnant and postpartum patients. The program, founded by Nancy Byatt,…
The HPV vaccine is not just for girls and can protect against various cancers in boys. It is most effective when administered early, before the age of 13. HPV is a common sexually transmitted infection that can affect boys even without consensual sexual activity. The vaccine is safe and has been proven effective, with minimal…
Medical residents at Spaulding Rehabilitation Hospital, affiliated with Harvard Medical School, successfully taught high school students about lifestyle medicine. The curriculum, developed by the American College of Lifestyle Medicine, included three in-person sessions. Although there were barriers such as student transportation and time constraints, the residents were able to engage the students and educate them…
The Health Care Inc. newsletter discusses how the healthcare industry in the US has consistently taken advantage of the public, regardless of who is in power. Costs for hospitalizations, surgeries, checkups, devices, and drugs remain higher in the US compared to other countries. This trend has remained consistent under every president in the past three…
Martin Scivier, a diabetes advocate, expresses concern about the lack of training and understanding among carers in managing diabetes, especially in the use of technology, for older people in UK care homes. He highlights the need for improved skills and knowledge among carers to ensure safe and quality care for older individuals with diabetes. Research…
Researchers at Tohoku University have found that astrocytes play a critical role in determining the formation of long-term memories. They discovered that acidifying astrocytes did not affect short-term memory but prevented the retention of memories in the long term. By using optogenetics to manipulate astrocyte function, they found that stimulating astrocytes in the amygdala impacted…
Preliminary research presented at the American Heart Association’s Resuscitation Science Symposium 2024 found that starting CPR within minutes of a cardiac arrest significantly increases the chances of survival and protecting brain function. A study of nearly 200,000 cases showed that receiving bystander CPR within two minutes resulted in an 81% higher survival rate and 95%…
Doctors are cautious about linking weight loss drug tirzepatide to the death of a nurse in Scotland. Susan McGowan took tirzepatide for two weeks before her death, with pancreatitis and septic shock listed on her death certificate. Medical experts believe it may be difficult to prove if tirzepatide caused her death. Trials of tirzepatide have…
A recent study conducted by researchers from the Karolinska Institutet in Sweden found that a child’s body weight pattern during the critical years of lung development can have long-lasting effects on lung function. The study, which involved 3,200 children, concluded that both high and low BMI values can result in impaired lung function in adulthood….
Specialty medications are expected to make up 65% of drug spending by 2025, leading health systems to establish in-house specialty pharmacies. However, challenges such as workflow inefficiency, medication non-adherence, and hindered patient access can impact the success of these programs. To address these issues, health systems should focus on enhancing operational efficiency through automated systems,…
Our gut health is essential for overall wellness, as it plays a crucial role in immunity, mental health, and digestion. Poor gut health can lead to various issues, while a balanced gut can support immune system and mental well-being. Certain foods can nourish the gut microbiome and support digestive health, including fermented foods like yogurt…
patients with cirrhosis in a randomized controlled trial.” Kwo emphasized the potential benefits of using SGLT2 inhibitors in this patient population, suggesting that further research is needed to fully understand the efficacy and safety of this treatment approach. Source link
Good morning, everyone! As we start a new work week, let’s get back into the routine with a cup of pistachio creme and some interesting news. GSK is leaving the biotechnology industry trade group BIO, following other companies like Pfizer and UCB. The pharmaceutical industry may have a chance to adjust the Medicare drug pricing…
The increase in national insurance contributions for employers has sparked anger and confusion, especially in social care and GP surgeries, which are not exempt from the increase. The Royal College of General Practitioners and the BMA are demanding assurances that practices will receive the same protections as the rest of the public sector. Without additional…
Community health workers in small cities like Huron, South Dakota, are helping residents navigate the healthcare system, especially those facing barriers like poverty, language difficulties, or lack of insurance. These workers provide education on managing chronic health conditions, assist with insurance and billing issues, and help arrange medical appointments. The program has been successful in…
Research presented at the American Heart Association’s Resuscitation Science Symposium 2024 found that women were less likely to receive CPR in public compared to men. However, when assisted by 911 telecommunicators, bystander CPR rates for women and men were similar, highlighting the importance of telecommunicator assistance during cardiac emergencies. The study identified 2,400 out-of-hospital cardiac…
New research presented at the Obesity Week 2024 meeting suggests that the oral semaglutide 25 mg dose is just as effective in promoting weight loss and other positive outcomes as the investigational 50-mg oral dose and the injectable 2.4-mg dose. The OASIS 4 trial showed that the 25-mg dose may be an effective option for…
Long COVID, a condition with lingering symptoms like fatigue, chronic cough, and brain fog, may be affecting more people than previously believed. A recent study by researchers at Mass General Brigham found that nearly 23% of U.S. adults report symptoms of long COVID, a much higher rate than previously thought. The study used an AI…
The advancement of genetic testing has the potential to revolutionize patient care through precision medicine. However, challenges such as data privacy and sharing need to be addressed for widespread implementation. Collaborative efforts in genetic testing, such as sharing de-identified data in registries, are leading to advancements in medical knowledge and patient care. Integration with Electronic…
Patients who did not have their patella resurfaced during total knee arthroplasty had higher rates of revision, according to data presented at the American Association of Hip and Knee Surgeons Annual Meeting. Data from over 162,000 patients showed that unresurfaced patellas had a 1.6% higher revision rate compared to resurfaced patellas. While 1-year results were…
Tammy Clemons, a sickle cell disease patient, finds herself in the emergency room with excruciating pain. She recalls past hospital visits and family tragedies, including the loss of her brother and sister. Despite her pain, Clemons navigates the complexities of her illness, treatment options, and reproductive decisions. She interacts with her doctor, Dr. Saif, who…