, 2025-04-22 05:38:00 Workouts are great, but what happens when your commitment to fitness pushes your body beyond its limit? It can even be deadly. For a 41-year-old fitness enthusiast from Scotland with an orange belt in karate, what began as an intense session soon spiraled into a medical emergency most gym-goers are unaware of….
Darrell E. White, MD , 2025-04-21 14:18:00 April 21, 2025 5 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . ” data-action=subscribe> Subscribe We were unable to process your request. Please try…
Paolo del Vecchio , 2025-04-21 08:30:00 At the age of 23, after years of mental health problems, addictions, and trauma, I found myself on a Philadelphia subway platform ready to end my life. Thankfully, I found help and got better. But due to the actions of the Trump administration, many others face a bleak future…
, 2025-04-22 05:00:00 Medication-induced disruption of sterol biosynthesis poses significant risks to brain development and function. Credit: Julio Licinio An editorial published in Brain Medicine raises the alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common prescription medications. The editorial, “Medication-induced sterol disruption: An overlooked…
, 2025-04-22 03:34:00 University of Oklahoma researchers recently launched the Children’s Environmental Health Center in the U.S. Southern Great Plains, a groundbreaking initiative dedicated to advancing research on children’s health and environmental exposures, following a year of preparation. Funded by a $1.8 million grant from the U.S. Environmental Protection Agency, this new center aims to…
, 2025-04-21 11:37:00 Migraine with aura is the most prominent individual risk factor for unexplained stroke in adults younger than 50 years, particularly in women and in those with patent foramen ovale (PFO), a new study showed. While investigators found that both traditional and nontraditional risk factors contributed significantly to cryptogenic ischemic stroke (CIS) risk…
Richard L. Lindstrom, MD , 2025-04-21 14:18:00 April 21, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable…
Adam Feuerstein , 2025-04-21 12:30:00 Adam Feuerstein is a senior writer and biotech columnist, reporting on the crossroads of drug development, business, Wall Street, and biotechnology. He is also a co-host of the weekly biotech podcast The Readout Loud and author of the newsletter Adam’s Biotech Scorecard. You can reach Adam on Signal at stataf.54….
, 2025-04-22 04:10:00 Credit: Unsplash/CC0 Public Domain Middle-aged Americans have demonstrated some of the highest levels of loneliness in a new study assessing tens of thousands of 50-to-90-year-olds across 29 countries. The research, published in Aging & Mental Health, shows that loneliness generally increases with age—with only the United States and the Netherlands representing places…
, 2025-04-22 03:40:00 A new study offers insight into what is happening in our brains when our working memory must use its limited resources to remember multiple things. Researchers found that two parts of the brain work together to ensure that more brain resources are given to remember a priority item when a person is…
, 2025-04-22 02:38:00 TOPLINE: Chronic lymphocytic leukemia (CLL) cell–derived exosomes demonstrated the ability to alter healthy donor cell function and suppress normal blood cell formation. These particles affected monocytes, fibrocytes, and lymphocytes, leading to changes in gene expression and protein levels that may contribute to disease progression. METHODOLOGY: Researchers examined CLL cell–derived exosomes and their…
Barbara C. Erny, MD; Alex Young , 2025-04-21 14:18:00 April 21, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We…
Ed Silverman , 2025-04-21 13:18:00 Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because that oh-so familiar routine of deadlines, online meetings, and phone calls has predictably returned. But what can you do? The world, such as it is, continues to spin. So time to…
, 2025-04-21 18:40:00 Adverse pregnancy outcomes (APOs) mediate a small proportion of the association between prepregnancy obesity and cardiovascular disease (CVD) risk in midlife, according to a study published in the April 22 issue of the Journal of the American College of Cardiology. Jaclyn D. Borrowman, Ph.D., from Northwestern University in Chicago, and colleagues examined…
, 2025-04-22 02:42:00 Using pilocarpine eye drops following Kahook Dual Blade (KDB) goniotomy surgery may improve clinical outcomes for patients with glaucoma and reduce the need for future medications, according to new research published by faculty members and trainees in the Department of Ophthalmology at the University of Colorado School of Medicine. “The KDB goniotomy is a minimally invasive glaucoma…
, 2025-04-21 11:39:00 Emerging evidence suggests that how you eat, as well as what you eat, can have an impact on obesity. Recent research showed that the number of chews and bites and meal duration can affect feelings of hunger and satiety and, by extension, how much food is consumed. In a recent small study…
Caitlyn Stulpin , 2025-04-21 18:26:00 April 21, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Mike Damiano — Boston Globe and Hilary Burns — Boston Globe , 2025-04-21 22:00:00 Harvard University sued the Trump administration on Monday, alleging that the government’s campaign to alter the school’s policies while cutting off research funding is unconstitutional. In a lawsuit filed in federal court in Boston, the university’s lawyers argued that the government’s “attempt…
, 2025-04-21 19:22:00 Credit: RDNE Stock project from Pexels Deciding whether to start hormone therapy during the menopause transition, the life phase that’s the bookend to puberty and when a woman’s menstrual cycle stops, is a hotly debated topic. While hormone therapy—replacing the hormones that were previously produced by the body with synthetic medication—is recommended…
, 2025-04-22 01:23:00 Women who experience urinary incontinence after giving birth may get just as much relief from telehealth as they do from physical therapy, a new UC San Francisco study has found. It is the first comparison of telehealth to in-person pelvic physical therapy, and the results open the door to new ways of…
, 2025-04-21 11:48:00 To assess how a patient with pulmonary arterial hypertension (PAH) is faring on therapy, look at the right heart, said Anjali Vaidya, MD, in a presentation at the Annual Meeting of the American College of Cardiology. When it comes to right heart performance, “the echo doesn’t lie,” said Vaidya, a professor of…
Jennifer Byrne , 2025-04-21 18:27:00 April 21, 2025 4 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Jonathan Wosen , 2025-04-21 22:13:00 National Institutes of Health director Jay Bhattacharya on Monday asserted that the agency remains committed to research that advances the health of minorities — despite the Trump administration’s sharp focus on rolling back programs dealing with diversity, equity, and inclusion. Bhattacharya said that President Trump’s executive orders, which state that…
, 2025-04-21 21:00:00 Credit: Unsplash/CC0 Public Domain A multisource observational study aimed to quantify the change in prevalence and health care utilization of psilocybin users between 2014 and 2023. The study found that the prevalence of psilocybin use increased across all age groups, with those with mental or physical comorbidities among the most common users….
, 2025-04-21 23:48:00 Scientists have identified a gut microbiota profile that can help forecast future cardiovascular events in patients with heart disease, paving the way for more personalized treatment and early interventions. Study: A microbiota pattern associated with cardiovascular events in secondary prevention: the CORDIOPREV study. Image Credit: Shutterstock AI Generator / Shutterstock.com A recent study…
, 2025-04-21 12:00:00 TOPLINE: Immune-related adverse events (irAEs) were associated with significantly improved progression-free survival (PFS) and overall survival (OS) in patients with extensive-stage small cell lung cancer (SCLC) who received chemoimmunotherapy compared with that in those who did not experience such events. METHODOLOGY: Researchers conducted a retrospective analysis of 399 consecutive patients (median age,…
Holly Liptak; Manjot K. Gill, MD , 2025-04-21 20:00:00 April 21, 2025 1 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We…
Bob Herman , 2025-04-21 22:26:00 UnitedHealth Group spent nearly $1.7 million on security for its top executives last year, and it appears the expenses all occurred in the final weeks of 2024, after top executive Brian Thompson was killed, new filings show. Thompson was the CEO of UnitedHealthcare, the company’s health insurance division. He was…
, 2025-04-21 21:13:00 Credit: Pixabay/CC0 Public Domain Primary progressive aphasia is a neurological condition that causes a gradual decline in language abilities. There is no cure or medication that can reverse or stop the progression of PPA. The standard practice in the clinical setting is speech-language therapy to help people with PPA maintain their ability…
, 2025-04-21 17:59:00 Nearly 30 million adults in the United States experience alcohol use disorder (AUD), but the vast majority of people with this condition do not receive treatment. A new study led by Boston University School of Public Health (BUSPH), BU Chobanian & Avedisian School of Medicine, and Boston Medical Center (BMC) researchers indicates…
, 2025-04-21 12:00:00 TOPLINE: Patients with obesity and early rheumatoid arthritis (RA) had an increased risk for remission failure after 6 months of starting methotrexate treatment, regardless of the presence of underlying comorbidities. METHODOLOGY: Researchers analysed data from a population-based case-control study linked to the Swedish Rheumatology Quality Register to investigate the association of obesity…
Marissa Plescia , 2025-04-21 20:32:00 Aeroflow Health, a health tech company, last week announced a new diabetes management program, which aims to improve adherence, outcomes and care coordination for health plan members. Asheville, North Carolina-based Aeroflow Health was founded in 2001 and offers an array of medical devices covered by insurance. The company has four…
, 2025-04-21 18:34:00 The White House has replaced a federal website that provided information about COVID-19 with a web page titled “Lab Leak: The True Origins of COVID-19” that cites the controversial theory that the virus was leaked from a Wuhan lab in China. The previous websites, covidtests.gov and covid.gov, provided information on treatment options…
Holly Liptak; Manjot K. Gill, MD , 2025-04-21 20:00:00 April 21, 2025 2 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We…
Bob Herman , 2025-04-21 14:57:00 Bob Herman covers health insurance, government programs, hospitals, physicians, and other providers — reporting on how money influences those businesses and shapes what we all pay for care. He is also the author of the Health Care Inc. newsletter. You can reach Bob on Signal at bobjherman.09. This is the…
, 2025-04-21 21:04:00 Credit: Unsplash/CC0 Public Domain Using pilocarpine eye drops following Kahook Dual Blade (KDB) goniotomy surgery may improve clinical outcomes for patients with glaucoma and reduce the need for future medications, according to new research published by faculty members and trainees in the Department of Ophthalmology at the University of Colorado School of…
, 2025-04-21 18:03:00 Background and aims The incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) has been escalating annually, positioning it as the leading cause of chronic liver disease worldwide. Ursolic acid has demonstrated promising therapeutic efficacy in managing MASLD, thereby justifying the need for an in-depth exploration of its pharmacological mechanisms. This study aimed…
, 2025-04-21 12:00:00 TOPLINE: Older adults with severe herpes zoster were at a heightened risk of developing dementia, especially those aged 50-65 years, when compared with both matched control individuals from the general population and patients hospitalised for other infections. METHODOLOGY: Researchers conducted a cohort study from January 2001 to December 2023 in Italy to…
Ashish Mandavia , 2025-04-21 13:44:00 You get an instant confirmation when you order groceries. You track your Uber as it turns the corner. You know the cost of a hotel room before you book it. These are the digital expectations on which we rely. Yet when it comes to our health, we remain in the…
, 2025-04-21 18:58:00 United Arab Emirates-based Burjeel Holdings, a healthcare services provider, and Hippocratic AI, a generative AI company developing safety-focused large language models for healthcare, announced a strategic partnership to alter healthcare delivery. Burjeel Holdings operates in parts of the Middle East and North Africa. Hippocratic AI and Burjeel announced the alliance during the…
Justin Cooper , 2025-04-21 19:28:00 April 21, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Associated Press , 2025-04-21 19:13:00 WASHINGTON — The Supreme Court seemed likely to uphold a key preventive-care provision of the Affordable Care Act in a case heard Monday. Conservative justices Brett Kavanaugh and Amy Coney Barrett appeared skeptical of arguments that Obamacare’s process for deciding which services must be fully covered by private insurance is unconstitutional. The case…
, 2025-04-21 18:48:00 Overall cancer mortality rates declined from 2001 through 2022, while cancer incidence rates decreased from 2001 through 2013 and stabilized through 2021, according to the 2024 Annual Report to the Nation on the Status of Cancer published online April 21 in Cancer. Recinda L. Sherman M.P.H., Ph.D., from the North American Association…
, 2025-04-21 18:06:00 The percentage of children under 18 years old with anxiety and depression increased steadily from 2016 to 2022, according to publicly available data from the National Survey of Children’s Health that were analyzed by researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago. In contrast, there was no increase during…
, 2025-04-21 12:14:00 TOPLINE: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was associated with increased risks for various adverse kidney outcomes, including new-onset chronic kidney disease (CKD) and worsening kidney function in patients younger than 21 years. Those with preexisting CKD or acute kidney injury (AKI) faced higher risks for severe adverse outcomes such…
Frank Vinluan , 2025-04-21 17:36:00 A cancer drug from partners AstraZeneca and Daiichi Sankyo currently approved as a second-line or later treatment for metastatic breast cancer has interim clinical data showing it helped patients live longer without their disease worsening in the first-line setting, results that could support further expanding use of this targeted therapy….
Moira Mahoney , 2025-04-21 14:21:00 April 21, 2025 4 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Anil Oza , 2025-04-21 16:03:00 The National Institutes of Health appears to be preparing to prohibit the awarding of new grants to any institutions that have DEI programs or boycott Israeli companies, in what would be an escalation of the Trump administration’s use of research funding as leverage to dismantle activities at universities that it…
, 2025-04-21 17:23:00 pEtn depletes DAG from CD8+ T cells and impairs their function. Credit: Nature Cell Biology (2025). DOI: 10.1038/s41556-025-01650-9 A team of researchers from the University of Chicago, in collaboration with researchers from the University of Pittsburgh, has identified a novel oncometabolite that accumulates in tumors and impairs immune cells’ ability to fight…
, 2025-04-21 17:13:00 Newly published results of a randomized, controlled clinical trial in Japan among more than 170 children aged 1 to 6 who underwent surgery, show that by using EEG readings of brain waves to monitor unconsciousness, an anesthesiologist can significantly reduce the amount of the anesthesia administered to safely induce and sustain each…