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CAR T cells target senescent cells, improve healthspan in mice

CAR T cell therapy pioneered at Memorial Sloan Kettering Cancer Center (MSK) is showing promise in treating age-related diseases, such as metabolic decline, and could extend lifespan. The approach, using engineered immune cells to target senescent (nondividing) cells, has potential for diseases like chronic obstructive pulmonary disease (COPD), nonalcoholic steatohepatitis (NASH), osteoarthritis, metabolic syndrome, and…

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Can ‘Soda Taxes’ Improve Our Health?

A new study suggests that taxes on sugary beverages like soda can reduce demand and may improve public health. Research shows that sugary drinks have little nutritional value, and their consumption can increase the risk of diabetes, heart disease, and other chronic diseases. This has led to the introduction of beverage taxes in U.S. and…

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New, Updated Guidelines for Comprehensive Epilepsy Care

The first updated guidelines for specialized epilepsy centers in a decade focus on addressing the overall well-being of patients, including genetic testing and counseling, mental health screening, and special attention to special-needs populations. This shift reflects a move toward comprehensive care beyond seizure management. The guidelines, released by the National Association of Epilepsy Centers, were…

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Oral Sulopenem found as effective as Amoxicillin/Clavulanate for Uncomplicated UTI in Women in phase 3 trial

A phase 3 trial found that oral Sulopenem is as effective as Amoxicillin/Clavulanate for treating uncomplicated urinary tract infections (UTI) in women. The study suggests that Sulopenem could be a viable alternative to the commonly prescribed antibiotic for UTIs. The findings of the trial indicate that Sulopenem could potentially provide a new treatment option for…

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Simplifying the Maternal Care Network

The U.S. maternal healthcare system is failing, especially for ethnic-racial minorities and those of lower socioeconomic status. Maternal mortality rates are high, with black women being at a significantly higher risk. Complications often arise after childbirth, and the current system does not effectively address the specific health needs of each patient. However, there is hope…

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New measures introduced to address concerns around epilepsy drug use in men

The inquiry into the use of valproate among pregnant women in Ireland remains without a chair six months after being announced. Precautionary steps are being introduced regarding the prescribing of sodium valproate to men due to potential increased risk of neurodevelopmental disorders in children. The European Medicines Agency advised new precautionary measures, including specialized supervision,…

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Sacituzumab Govitecan Plus Pembrolizumab Proves Active in Advanced Urothelial Carcinoma

A combination of sacituzumab govitecan and pembrolizumab showed a “high response rate” in patients with advanced urothelial carcinoma previously treated with platinum-based chemotherapy. In the TROPHY-U-01 trial cohort, 41 patients were treated with the combination, and a 41% objective response rate was observed. The median duration of response was 11.1 months, median progression-free survival was…

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February ’24: The Third International CTE Awareness Month

CTE awareness month is aimed at promoting dialogue and education about Chronic Traumatic Encephalopathy, a neurodegenerative disease linked to repeated traumatic brain injuries (TBI) commonly seen in athletes and military veterans. Its symptoms include cognitive, mood, and behavioral changes, with no definitive answer regarding its causes. The Concussion Legacy Foundation (CLF) is dedicated to ending…

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Advocates Say a Practice Harms Disabled Children, Yet Congressional Action Is Stalled

A 9-year-old boy with autism in a North Carolina classroom was physically restrained and secluded multiple times. Federal law does not prohibit this, leading to a lack of accountability and oversight. Thousands of children, particularly those with disabilities and students of color, are subjected to these practices, which can be dangerous and traumatizing. Legislation to…

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Covid inquiry: Tears and tensions as Sturgeon takes the stand

Scotland’s inquiry on the handling of the pandemic reveals that half of the country’s deaths in the first wave occurred in care homes. Former health secretary Jeane Freeman stated regret over these preventable deaths and emphasized that testing capacity was a primary issue. Former first minister Nicola Sturgeon admitted to regrets and said she should…

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Data show clinical trials are becoming more inclusive

A new meta-analysis from the Hackensack Meridian School of Medicine and Hackensack Meridian Health Research Institute shows a positive trending shift towards equity and inclusivity in clinical trials and medical research. The analysis of clinical trials from 2017 to 2022 including New Jersey patients reveals more diverse representation and better reporting of race and ethnicity…

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How I Plan for Specific Tasks With Geographic Atrophy

Joan Kathryn, 79, was diagnosed with age-related macular degeneration (AMD) in 2008. She has developed wet AMD in her left eye and geographic atrophy (GA) in both eyes. The condition has made it difficult for her to recognize faraway faces, read fine print, and find small objects. Despite the challenges, she has adapted by using…

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Organ Donations Increased in Québec After MAiD

Organ donations after medical assistance in dying (MAiD) accounted for 14% of total deceased donations in Quebec in 2022, according to new research. The study found that since 2018, there has been an increase in referrals and completed cases for organ donations after MAiD. During the study period, Transplant Québec received 245 referrals for donation…

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Best Fiber Supplements For 2024: Boost Your Digestive Health

Dietary fiber from fruits, vegetables, whole grains, and legumes offers essential health benefits, such as aiding digestion, controlling blood sugar, lowering cholesterol, and contributing to weight management. If it’s difficult to get enough fiber from regular meals, fiber supplements can help fill the gap. There are various options available, including gummies and capsules, for both…

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Health Budget 2024: Key healthcare initiatives unveiled

The health budget for 2024 has been announced, with a focus on key healthcare initiatives. The initiatives aim to improve the overall healthcare system and address current challenges. The budget will allocate funds to support the implementation of these initiatives, including investments in technology, infrastructure, and healthcare services. The goal is to enhance the quality…

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Health and social care professionals welcome introduction of discipline managers to children’s disability teams

The HSE has agreed to introduce interim discipline managers in Children’s Disability Network Teams (CDNTs) after concerns were raised by various professional organizations about clinical governance and risk management in children’s disability services. The new roadmap for service improvement aims to address an imbalance in service provision and improve access to services for children and…

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Prenatal Infections Increase Psychiatric Symptom Risk in Children

Prenatal infections could be a risk factor for psychiatric symptoms in children, according to recent research. The study, based on the Generation R Study, found that exposure to prenatal infection was linked to higher total, internalizing, and externalizing problems across development. The research, which analyzed data from over 3,500 mother-child pairs, used linear mixed-effects models…

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How Kakao Healthcare’s latest AI-powered mobile diabetes app works and more AI briefs

Kakao Healthcare has launched the PASTA app for diabetes management, which provides real-time blood sugar data and nutrition information. Microsoft has partnered with South Korean company Seegene to integrate its AI services into the SG OneSystem for PCR-based diagnostic solutions. Aevice Health and Jiva.ai are working on an AI-driven system to predict asthma exacerbations using…

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KFF Health News' 'What the Health?': The Struggle Over Who Gets the Last Word

Julie Rovner hosts KFF Health News’ weekly health policy news podcast, “What the Health?” In the latest episode, panelists discuss abortion laws, medical bills, and misinformation. They also share recommendations for relevant health policy stories. The panelists also highlight the upcoming oral arguments in the Supreme Court regarding the future of the abortion pill mifepristone…

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Vertex data, Aduhelm, & Woodcock retires

This episode of “The Readout LOUD,” STAT’s biotech podcast, covers a range of topics including what makes a blockbuster drug, the implications of Aduhelm for biotech, and the retirement of a significant FDA figure. They also discuss Vertex Pharmaceuticals’ novel pain drug and its success in clinical trials. The episode offers more information on these…

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‘Rare positive result’ in trial of new support intervention for people with dementia and their family caregivers  

The NIDUS-Family package of care and support focuses on helping people with dementia and their family caregivers attain their personal goals. The package can be delivered by phone, video call, or in person and aims to help the recipient meet their own individual goals, including increasing activity, improving mood, sleep, and appetite, enhancing relationships, and…

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Sleeve gastrectomy vs. Roux-en-Y gastric bypass

A study in JAMA Network Open compares the outcomes of laparoscopic sleeve gastrectomy (SG) and laparoscopic Roux-en-Y gastric bypass (RYGB) for weight loss surgery. Since 2017, SG has become more popular than RYGB, despite previous studies showing RYGB provides better long-term weight control. The study found that both surgeries had similar perioperative complications, but RYGB…

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Treating Geographic Atrophy: What to Consider

The author discusses her decision to pursue treatment for geographic atrophy (GA), an advanced form of dry age-related macular degeneration (AMD). She explains her experience living with GA, her decision-making process, and her concerns about potential long-term side effects and the risky treatment for GA. She expresses her hope that the treatment will slow the…

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Pickleball Boom Nets New Healthcare Opportunities

Pickleball’s popularity has led to a rise in injuries and associated medical costs in the US. However, some healthcare organizations are now partnering with the pickleball community to provide injury prevention education, care, and build lasting relationships with players. For example, the Cedars-Sinai Kerlan-Jobe Institute in Los Angeles and Humana have formed partnerships with the…

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Best Shampoo For Oily Hair In 2024: Say Goodbye To Grease

Having oily hair can be uncomfortable and erode self-confidence, but proper hair care routines and the right shampoo can help manage and balance oily hair. Some of the best shampoos for oily hair include Neutrogena T/Sal Therapeutic Shampoo, L’Oreal Paris Elvive Extraordinary Clay Rebalancing Shampoo, Aveeno Scalp Soothing Apple Cider Vinegar Blend Shampoo, Paul Mitchell…

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Deucravacitinib safer and more effective than apremilast for treating moderate to severe scalp psoriasis

A study has found that deucravacitinib is both safer and more effective than apremilast for treating moderate to severe scalp psoriasis. These findings suggest that deucravacitinib may be a promising treatment option for individuals with this condition. The study’s results provide valuable information for healthcare providers and patients seeking effective treatments for scalp psoriasis. This…

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Coordination of Benefits: An Overlooked Pillar of Medicaid Programs

Medicaid is a vital healthcare safety net in the U.S., with $824 billion in spending in 2022. One important but lesser-known aspect is the coordination of benefits, which ensures efficient management of funding sources and prevents overutilization of services. This practice also maximizes financial resources, promotes fair distribution of resources, and mitigates fraud and abuse….

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SGLT-2i and GLP-1RA Combination Therapy Reduces Adverse Cardiovascular Events

Combining sodium-glucose cotransporter-2 inhibitor (SGLT-2i) and glucagon-like peptide-1 receptor agonist (GLP-1RA) therapy is associated with a lower incidence of cardiovascular events in patients with type 2 diabetes and a recent acute myocardial infarction. The study found that the combination therapy had a reduced incidence of major adverse cardiovascular events compared to either therapy alone. The…

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Navigating Healthcare Software with Cerner and Epic EMR

The article provides an analysis of the Cerner and Epic EMR healthcare software platforms, outlining their features, pros and cons, and pricing. Cerner EMR, owned by Oracle, offers an adaptable, integrated solution for healthcare organizations, catering to various specialties and providing valuable resources for patient care. However, it may have navigation issues and limited capabilities…

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The latest on Novavax, Merck, Bluebird

In biotech news, Merck reported strong fourth-quarter earnings and a forecast for 2024 sales with an increase of 6%, while Roche and Sanofi also reported their earnings. The biotech industry is affected by the Federal Reserve’s decision not to cut interest rates, causing a 2% dip in the XBI index. Bluebird Bio’s financial results will…

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Breast implant illness: we must counter misinformation around this mysterious condition

Consultant plastic surgeon Nora Nugent from the UK refutes misinformation about breast implant illness and discusses the difficulty in definitively attributing systemic symptoms to silicone breast implants. She describes the numerous symptoms reported by women, and the challenges in diagnosing the condition. She also highlights the lack of evidence linking silicone implants to autoimmune or…

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New cancer cases to soar 77% by 2050: WHO

The World Health Organization’s cancer agency has warned that the number of new cancer cases will rise to over 35 million in 2050, a 77% increase from 2022. Factors such as tobacco, alcohol, obesity, and air pollution contribute to this rise. The most developed countries are expected to see the highest increase in case numbers,…

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Putting the Power of Motherhood in Your Hands

A new research study called PowerMom, led by Tolúwalàṣé (Laṣé) Ajayi, aims to address disparities and inequities in maternity care for pregnant individuals in the United States. The study uses a smartphone app that collects data from expectant mothers, including health-related information, to help identify the patterns and common concerns experienced during healthy pregnancies. The…

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PCOS May Lead to Memory, Decision-Making Problems Later on

A study found that individuals with polycystic ovary syndrome (PCOS) may have lower cognitive test scores and worse brain tissue integrity compared to those without the condition. The study used data from the Coronary Artery Risk Development in Young Adults Women’s Study, including over 900 women, 66 of whom had PCOS. The PCOS group showed…

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ACO REACH Challenging to Succeed in First Year But Tools Can Help

The ACO REACH program offers a chance for risk-bearing organizations to focus on health equity and improve patient outcomes. The program encourages participants to work with underserved communities and address health equity barriers. However, there are challenges, including managing unfamiliar patient populations and providers, and navigating the Dunning-Kruger Effect. Many organizations struggle with ROI, but…

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Cannabis legalisation to be debated today

A group of Irish Medical Organisation (IMO) doctors are concerned about proposed legislation to legalize cannabis possession for personal use and remove the stigma of a criminal conviction for such offenses. The doctors argue that decriminalization, as recommended by the Citizens’ Assembly, would be a more suitable approach. They have written to government officials ahead…

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