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How to Get Enough Sleep

Pediatric nurse and mother, Claire Park, has been struggling with atopic dermatitis (AD) on her hands, leading to nighttime itching that disrupts her sleep. Research has found that many people with AD have trouble sleeping due to itching. Poor sleep due to AD can impact mental function, emotional well-being, and quality of life. The relationship…

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Sweetened Drinks Spell Hormone Trouble for Women

A population-based cohort study found that women consuming even modest amounts of fructose from sugar-sweetened beverages are more likely to have elevated androgen levels, with implications for conditions such as acne and hirsutism. The study included 136,384 individuals and found that consuming at least 10g/day of fructose from sugar-sweetened beverages was linked to lower SHBG…

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Researchers Say It Reduces Risk Of Metabolic Syndrome

Researchers found that the Atlantic Diet, a traditional diet from Portugal and northwest Spain, can help reduce the risk of metabolic syndrome. Metabolic syndrome consists of elevated blood pressure, sugar, triglycerides, abdominal fat, and low HDL cholesterol, increasing the risk of heart disease, diabetes, and stroke. The diet emphasizes fish, seafood, starch-based foods, and moderate…

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Moderna & Ionis-Partnered Biotech Lands $94M in IPO Cash for Gene-Editing R&D

Metagenomi, a company focused on gene-editing tools to correct disease-causing mutations, raised $93.75 million from its IPO, priced at $15 per share. Its research uses high-throughput screening and AI technology to mine novel proteins. The company aims to develop new gene-editing tools capable of correcting any genetic mutation. Metagenomi’s preclinical pipeline spans 13 programs targeting…

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John Farrelly reappointed to lead Mental Health Commission

The Mental Health Commission (MHC) has reappointed John Farrelly as its chief executive for the next five years. Farrelly has 35 years of experience in health and social care services and has led the MHC since October 2018. He was responsible for enhancing the quality and safety of Ireland’s inpatient mental health services and overseeing…

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Heart Failure Medications: A Physician’s Guide for Optimization

The 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure recommends quadruple therapy with an angiotensin receptor-neurolysin inhibitor (ARNI), beta blocker, mineralocorticoid receptor antagonist (MRA), and sodium-glucose cotransporter 2 (SGLT2) inhibitor for patients with heart failure with reduced ejection fraction (HFrEF). The article reviews the categories of heart failure, mechanisms, indications, contraindications, and adverse effects…

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Donald William Bethune | The BMJ

Don Bethune joined Papworth as a consultant in 1969 after training in hospitals in Newcastle and London. He was a pioneer in the operation and management of life support during open heart surgery, working with the relatively primitive heart-lung machine. He was the first consultant at Papworth with a special interest in open heart surgery…

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Heart attack symptoms in women are often different than men

Heart attack symptoms in women are different from men, often manifesting as sweating, nausea, dizziness, and unusual fatigue, which may occur while resting or asleep. Women should recognize their unique symptoms and work to reduce their risk of heart disease. Risk factors include diabetes, mental stress and depression, smoking, sedentary lifestyle, menopause, broken heart syndrome,…

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Study pinpoints APOE4’s harmful effect on lipids

Researchers at UNC School of Medicine have discovered a new link between APOE4 and Alzheimer’s disease. A study found that APOE4 increases the risk of the disease by compromising the function of brain cells known as astrocytes. APOE4 alters the composition of lipid droplets within astrocytes, which ultimately impairs their ability to clean up toxic…

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Atopic Dermatitis and Food Triggers

Atopic dermatitis (AD) can cause red, itchy skin flares linked to food allergies, but only 30% of people with AD have food triggers. It’s important to see a doctor before eliminating foods. Young children are more prone to AD, but about 90% outgrow it by age five. A food allergy causes hives, not AD, and…

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Study Suggests Mind-Body Benefits of GLP-1s

An analysis of health records found that people using GLP-1 medications for weight loss or diabetes were less likely to develop new diagnoses of depression or anxiety. This correlation was observed among both diabetics and non-diabetic weight loss patients, especially with the drug tirzepatide. While promising, the study’s findings are not conclusive, and it’s unclear…

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Best Eye Drops For 2024: Revitalize Your Vision

The article explains that dry eyes can cause discomfort and blurred vision, and provides tips for selecting the best eye drops for dry eyes. It also lists the best eye drops for dry eyes, red eyes, and allergies, and provides a brief description of each product. The article emphasizes the importance of consulting an eye…

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CDSCO Panel Tells Boehringer Ingelheim

The Central Drugs Standard Control Organization (CDSCO) panel has requested further study on the safety and effectiveness of using tenecteplase at a dosage of 0.25 mg/kg for treating acute ischemic stroke. This request was made to the pharmaceutical company Boehringer Ingelheim. The study will focus on evaluating the potential risks and benefits of this treatment…

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Limiting Cyberattack Blast Radius for Healthcare SaaS

Attorneys filed suit against Johns Hopkins University and its health system, alleging that they failed to secure IT systems, resulting in a theft of sensitive patient data. The lawsuit mentions a Zero-Day flaw in the MOVEit file transfer system. Other healthcare providers, including Harris Health, have also been affected by this flaw. As more hospitals…

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Adding Fruquintinib to Paclitaxel Improves PFS in Gastric, GEJ Cancer

Fruquintinib plus paclitaxel has shown promising results as a second-line treatment option for patients with advanced gastric or gastroesophageal junction (GEJ) cancer. The combination improved responses and progression-free survival (PFS) compared to paclitaxel alone, and there was a trend toward improved overall survival (OS) with fruquintinib. The FRUTIGA trial included 703 patients with advanced gastric…

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What we’ve learned from the Aduhelm mess

STAT publishes selected Letters to the Editor in response to First Opinion essays for robust, good-faith discussion. Jason Karlawish’s article on Aduhelm’s approval process raises concerns about the roles and incentives of pharmaceutical companies and the FDA. John Haaga supports Karlawish’s points and advocates for public funding of FDA and NIH research for objectivity. Adina…

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John Humphrey Wilfred Shaw

John Humphrey Wilfred Shaw was a medical doctor who studied at St John’s College, Cambridge, and later joined St Bartholomew’s Hospital in London in 1953. He worked as a GP in Redhill for 34 years and was the managing partner from 1985. After retiring in 1997, he attended literature classes and did research, publishing several…

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Triplet therapy including belamaf prolongs survival in multiple myeloma

A study presented during the February 2024 session of the American Society for Clinical Oncology Plenary Series shows that triplet therapy of belantamab mafodotin (belamaf) plus bortezomib and dexamethasone significantly improves outcomes for patients with relapsed or refractory multiple myeloma (RRMM), with an acceptable safety profile. The trial found that the median progression-free survival (PFS)…

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A budget friendly bioprocess control station for microbial applications

Distek, Inc. introduces the BIOne 250 Bioprocess Controller, a cost-effective solution for microbial bioprocessing. This model is a process optimized design of the BIOne 1250 benchtop bioreactor system, with a user-friendly interface and scalability for evolving needs. It offers sophisticated functionality and integrates with other bioprocess equipment. The controller’s reliability and precision ensure consistent and…

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Is It Dry Skin or Atopic Dermatitis?

George Kramb, 29, from San Diego, struggled with what he thought was severe dry skin for years. It was flaky, irritated, and cracked, especially in the winter. He tried over-the-counter ointments without success until he was diagnosed with atopic dermatitis (AD) in his teens. AD causes itchy rashes, skin discoloration, pain, and thickened skin. It’s…

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Analysis Finds Allergens in Many Topical Scar Products

A study found that over half of over-the-counter topical scar products contain allergens. Researchers searched for scar products on various retail websites and found 156 products. Of those, 55.2% contained at least one North American Contact Dermatitis Group (NACDG) allergen, with fragrance, phenoxyethanol, parabens, panthenol, and sodium benzoate being the most common. The study also…

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Expert Recommendations for American Heart Month

Nutrition is crucial for overall health and well-being, especially when it comes to heart health. To improve heart health through diet, it is important to understand expert recommendations on what to eat and what to avoid. Heart-healthy foods include sardines, green tea, and flaxseeds, while it is important to limit the intake of high-fat dairy…

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Parliamentary panel tells Health Ministry

A Parliamentary panel has advised the Health Ministry to keep the evaluation criteria for the NExT exam moderate, allowing ample time for preparation and to release the schedule early. They emphasized the need for a balanced approach to the evaluation process to ensure fairness for all candidates. The panel’s recommendation aims to reduce stress and…

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New climate healthcare study receives €2.5 million funding

A new study on climate change resilient healthcare has received almost €2.5 million in funding from the Health Research Board. Led by Prof Deirdre Bennett of University College Cork, the program aims to prepare healthcare professionals to actively contribute to resolving the climate crisis. The study, titled ‘Educating Healthcare Professionals for Climate Change Resilient and…

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Hologic AI-powered cancer screening system wins FDA approval

Hologic has received FDA clearance to market its Genius Digital Diagnostics System, which integrates AI with imaging technology to aid in detecting cervical cancer cells. The system, already available in Europe, Australia, and New Zealand, will be launched commercially later this year. By digitizing glass slides for analysis through the AI algorithm, the system claims…

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Do We Simply Not Care About Old People?

The covid-19 pandemic in America was predicted to be a wake-up call about the care of vulnerable older adults. The death toll and the chaos in nursing homes and reports of seniors suffering from isolation, depression, and neglect were shocking. There have been around 900,000 older adult deaths due to covid-19, but hoped-for decisive actions…

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The neurospychology of memory and aging

Special counsel Robert Hur’s report on President Biden’s handling of classified documents focused on the President’s age and alleged memory issues. Medical professionals are skeptical of armchair diagnoses. Memory and aging expert Joel Kramer noted that memory decline with age is not inevitable, and that memory issues in older age do not necessarily indicate underlying…

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Thomas George Parks | The BMJ

George Parks had a long and successful career in the medical field. After completing a fellowship at St Mark’s Hospital and the Royal London Hospital, he became a consultant surgeon at Armagh City and South Tyrone Hospital in 1970. In 1971, he took up a position as senior lecturer and consultant surgeon at the Royal…

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Lower Your Cholesterol in 11 Easy Steps

High cholesterol puts you at risk for heart disease, but there are ways to control it. Lower your LDL cholesterol and raise your HDL cholesterol by making simple lifestyle changes. For example, avoiding trans fats, losing weight, getting enough exercise, and incorporating soluble fiber, omega-3 fats, and healthy oils into your diet can help. Reducing…

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Tools on the Horizon for Managing Posttransplant cSCC Risk

The content discusses the challenges of treating advanced cutaneous squamous cell carcinoma (cSCC) in organ transplant recipients. The use of immune checkpoint inhibitors is limited due to the potential risk of organ rejection. Organ transplant recipients have a higher risk of developing cSCC, and treatment options are limited due to the impact of immunosuppressant medications….

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The Ultimate Guide To Top 5 Supplements

Gut health is crucial for overall bodily function, affecting digestion, nutrient absorption, immune function, metabolism, and mental health. Prioritizing gut health supports reduced inflammation, enhanced digestion, and lower risk of chronic diseases. The article introduces the top 5 gut health supplements: ColonBroom, Simply Nature’s Promise – ColonSweep, Dr. Tobias Colon 14 Day Cleanse, Health Plus…

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Superior Trunk Block Effective Phrenic-Sparing Alternative to Interscalene Block for Shoulder Arthroscopy

A study found that the superior trunk block (STB) is an effective phrenic-sparing alternative to the interscalene block for shoulder arthroscopy. The STB was found to provide comparable analgesia and motor block while avoiding the potential risk of phrenic nerve paralysis associated with the interscalene block. The study suggests that the STB can be a…

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Everly Health Partners With National Kidney Foundation, Expands Kidney Health Testing Suite

Everly Health is partnering with the National Kidney Foundation to improve education around chronic kidney disease and expanding its diabetes monitoring and kidney health testing suite for health plans and employers. Through this partnership, Everly Health’s health plan customers will identify patients at risk for chronic kidney disease, such as those with diabetes, and send…

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New drug combination reduces risk of death in advanced bladder cancer cases by 53 per cent

A new drug combination, enfortumab vedotin in combination with pembrolizumab, has been found to significantly reduce the risk of death in patients with advanced bladder cancer. The treatment improved median overall survival by over 15 months and almost doubled the length of median progression-free survival compared to standard chemotherapy. The Phase 3 trial involved 886…

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Short-Term Mortality Rate Near 50% in Children Who Receive VA-ECMO for Heart Disease

A study in the Journal of the American Heart Association found that pediatric patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for severe heart disease have a short-term mortality of 45.6%. The analysis included 28 studies with 1736 patients, showing a lower mortality rate for children with acute fulminant myocarditis compared to those with congenital heart…

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Digital twin company Unlearn secures $50M

Unlearn, an AI-enabled company, raised $50 million in Series C funding, bringing its total raise to over $130 million. The company creates digital twins of clinical trial participants using machine learning, providing researchers with insight into the participants’ health outcomes. Unlearn aims to run smaller clinical trials more quickly, and plans to invest in its…

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Senators Weigh Whether Health Care AI Needs a Leash

The Senate Finance Committee discussed the use of artificial intelligence in health care. Democrats want regulations for AI to prevent biased recommendations that result in inadequate or inappropriate care. The committee’s chairman, Ron Wyden, expressed concern about flawed algorithms and AI systems and has proposed the “Algorithmic Accountability Act.” The debate over the need for…

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