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Reducing the Impact of MS Relapses

For individuals with relapsing forms of MS, early treatment with an effective disease-modifying therapy (DMT) is crucial. The right medication can help manage symptoms, reduce the frequency of relapses, and slow the progression of the disease. It is important to work with a healthcare provider to find the most suitable DMT, as there are several…

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Apixaban for Cryptogenic Stroke With Atrial Cardiopathy?

In a study of patients with cryptogenic stroke and evidence of atrial cardiopathy without atrial fibrillation, the use of apixaban did not significantly reduce recurrent stroke risk compared with aspirin. The trial was stopped due to futility after enrolling 1015 of the planned 1100 patients. Recurrent stroke occurred at a similar rate in both groups,…

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Surgical robotics company Medical Microinstruments secures $110M and more digital health fundings

Medical Microinstruments, a surgical robotics company, secured $110 million in a Series C financing round led by Fidelity Management & Research Company, with participation from existing investors. The company offers the Symani Surgical System, a robotic technology for microsurgery and supermicrosurgery, allowing surgeons to replicate human hand movements at a micro level during soft tissue…

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Death and Redemption in an American Prison

Steven Garner, and his brother Glenn, were sentenced to life in prison without parole for the murder of a man. While in prison, Garner joined the nation’s first prison hospice program at Louisiana State Penitentiary in Angola. He cared for dying inmates for 25 years and collaborated with the prison warden to create a self-sufficient…

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Study fuels hope CAR-T cell therapy could treat autoimmune disease

German researchers have developed CAR-T therapy for autoimmune disorders such as lupus, multiple sclerosis, and rheumatoid arthritis. The therapy involves modifying a patient’s T cells in a lab to better target disease. The therapy has shown positive results in clinical trials, with patients experiencing a reduction or elimination of symptoms. Experts are cautiously optimistic but…

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Comprehensive analysis of immune checkpoint inhibitors reveals endocrine toxicity patterns

A new publication in Acta Materia Medica journal addresses the challenges of immune-related adverse events (irAEs) associated with immune checkpoint inhibitors (ICIs) in cancer treatment. The authors conducted a network meta-analysis of 55 randomized controlled trials involving 32,522 patients to rank the safety of various ICI therapies. They found that ICIs increase the risk of…

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Lessons From My Journey With Relapsing-Remitting MS

A neurologist diagnosed Darbi Haynes-Lawrence with relapsing-remitting MS 13 years ago, leaving her grappling with the reality of her disabling condition. This battle has included negative thoughts and skepticism from others due to her unseeable symptoms. She was initially denied support from doctors who claimed her issues were stress-related. After being diagnosed with MS, her…

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How Do Doctors Feel About Assisted Dying?

Public attitudes toward assisted dying are evolving, but it is also important to consider the opinions of doctors, as they may be the ones prescribing or administering life-ending medication in the event of a change in the law. A majority of the public, 65%, support legalizing assisted dying, and 50% of doctors support a change…

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340B Program Preserves, Improves Access to Rural Health Care

The President & CEO of a rural Vermont health system emphasizes the importance of the 340B Drug Pricing Program in enabling hospitals to provide affordable, high-quality health care to rural communities. The program allows hospitals to access prescription pharmaceuticals at a reduced price, helping them offer comprehensive services to low-income, senior, and medically vulnerable individuals….

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Organ donation legislation to pass Dáil and Seanad today

New funding of €1.6 million has been announced for organ donation and transplant services, in anticipation of the Human Tissue Bill passing both houses of the Oireachtas. The bill will introduce a new legal framework for organ donation, including an ‘opt-out’ register. Health Minister Stephen Donnelly stated that the funding will support the early phases…

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Prevalence of Childhood Rheumatic Heart Disease Increased Over the Past 30 Years

Rheumatic heart disease (RHD) in children under 15 has increased globally from 1990 to 2019, with higher incidence and prevalence rates. However, disability-adjusted life years (DALYs) and mortality rates have decreased during this time. RHD is more prevalent in less economically developed countries, with the burden being higher in Eastern Sub-Saharan Africa, North Africa, the…

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Detect-Ion contracted to develop spectral chemical threat detection device

Detect-Ion has secured a research contract with the Intelligence Advanced Research Projects Activity (IARPA) to develop a sensor to identify aerosol-based chemical threats. The company will develop a compact sensor platform called Spectral using AI to detect and identify aerosolized chemical threats, with the goal of making critical decision-making easier and faster. Rapid detection of…

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‘Fourth Wave’ of Opioid Epidemic Crashes Ashore, Propelled by Fentanyl and Meth

The United States is currently experiencing a fourth wave of the opioid epidemic, with experts identifying a significant increase in the use of multiple substances at the same time, especially the combination of fentanyl with methamphetamine or cocaine. Over 93% of fentanyl-positive urine samples contained additional substances, and the use of methamphetamine and fentanyl together…

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NIH study of ME/CFS points to clear biological hallmarks

Alison Sbrana contracted infectious mononucleosis as a college student, which led to her developing myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This disease affects 4.3 million American adults, leading to chronic fatigue, flu-like symptoms, and changes in the brain’s functionality. However, research on ME/CFS is limited, with no current treatment available. A recent study from the National…

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Chronic inflammation and inactivity may affect age-related changes in gene and protein expression in skeletal muscle

New research suggests that age-related changes in gene and protein expression in the skeletal muscles of older individuals may be influenced more by physical inactivity and chronic inflammation rather than primary aging processes. The study found that physical inactivity and chronic inflammation are the most important drivers of secondary aging, which are changes caused by…

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What Are Death Doulas?

End-of-life doulas provide emotional and practical support to individuals who are dying, as well as their families. The doulas work to personalize the dying person’s final days by helping them reflect on their life, plan for their death, and engage in activities or conversations that bring them comfort. Doulas may also provide support to family…

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What Skin Manifestations Are Associated With Pediatric IBD?

A single-center study found that many children with inflammatory bowel disease (IBD) also suffer from skin conditions. Researchers at Mayo Clinic in Rochester, Minnesota, reviewed the medical charts of 425 children and adolescents with Crohn’s disease or ulcerative colitis between 1999 and 2017. They found that acne, eczema, and perianal skin tags were the most…

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The Art And Science Of Facial Reconstruction With Dr. Artur Carandell

Facial surgery requires a balance between artistic expression and surgical precision, as highlighted by the National Institutes of Health. Dr. Artur Diaz Carandell is a highly experienced cranio-maxillo-facial surgeon with a commitment to detail and expertise in facial aesthetics, reconstruction, and rejuvenation. He utilizes innovative non-invasive surgical techniques and embraces scientific precision in his practice….

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Is Europe About to Overtake the U.S.’s Leadership Position in Healthcare Sustainability via Reprocessing?

In 2000, the FDA regulated the use of reprocessed single-use devices in the U.S. to address concerns about patient safety. Reprocessing has environmental benefits, reducing CO2 emissions and carbon footprints. As the U.S. falls behind, other countries like the UK and France are implementing sustainability efforts in healthcare, particularly in electrophysiology (EP). Reprocessing has potential…

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Smoking and lung cancer—70 long years on

Last week marked the 70th anniversary of the UK government recognizing that smoking causes lung cancer. Cases of lung cancer had increased significantly since the end of World War I, and epidemiological work by Richard Doll and Austin Bradford Hill solidified the link between smoking and the disease. The response to this risk was muted,…

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Expert explains why early treatment is important

Dr. Sarosh Irani, a neurologist and researcher at Mayo Clinic, explains the importance of early treatment for encephalitis, a disease involving inflammation of the brain. Encephalitis can be caused by infections or immune system issues, with two primary types: infectious and autoimmune. Symptoms can develop quickly and include headache, fever, and more severe manifestations such…

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Novel genetic locations associated with primary open-angle glaucoma identified

An international study has identified new genetic locations associated with primary open-angle glaucoma. It uses multiancestry biobanks and millions of samples from around the world. The findings, published in Cell Reports Medicine, detail ancestry and sex-specific genetic loci associated with POAG. It identified 17 new genetic loci associated with glaucoma, five of which were specific…

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Women Get More Health Benefits From Exercise Than Men

A recent study published in Cardiology has suggested that exercise benefits women more than men; conclusions are based on findings involving 400,000 survey respondents. Women who exercise regularly reduced their risk of early death by 24%, while men had only a 15% risk reduction. The benefits extended to protection from heart problems and strokes, further…

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FDA Approves Iloprost for Severe Frostbite

The FDA has approved iloprost injection for treating severe frostbite in adults to reduce the risk of amputation. A randomized trial showed that iloprost alone had a 0% risk of amputation based on bone scans, compared to 60% with buflomedil on day 7. The most common adverse events with iloprost are headache, flushing, heart palpitations,…

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COVID Vaccines Linked To Slight Increase In Heart And Brain Issues: Large-Scale Study

A study of nearly 100 million vaccinated individuals across eight countries found a slight increase in the risk of certain adverse health effects linked to COVID-19 vaccination. These effects include myocarditis, pericarditis, and Guillain-Barré syndrome. AstraZeneca’s vaccine was linked to a higher risk of Guillain-Barre syndrome and blood clots, while the Moderna vaccine was associated…

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Maven Clinic expands partnership with AT&T to give employees fertility, family benefits

AT&T has partnered with Maven Clinic to offer its employees access to virtual fertility and family-building support services. This includes guidance on egg freezing, adoption, IVF, and more. Maven Clinic also offers services for pregnancy, postpartum care, parenting, and pediatric support, as well as a program for menopause-related care. The expanded partnership gives AT&T employees…

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GLP-1s associated with reduced risk for depression, anxiety in patients with diabetes

Patients with diabetes who were prescribed GLP-1 receptor agonists were less likely to be diagnosed with depression and anxiety compared to those not on these medications. The GLP-1 receptor agonists included semaglutide, tirzepatide, dulaglutide, exenatide, and liraglutide. Patients without diabetes prescribed semaglutide also had a lower risk for anxiety and depression. Although the findings suggest…

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New study raises questions about niacin and heart health

A study published in Nature Medicine found that an excess of Vitamin B3, or Niacin, may increase the risk of cardiovascular disease. Researchers discovered that a metabolite of excess niacin, N1-methyl-4-pyridone-3-carboxamide (4PY), is linked to an increased risk of cardiovascular events. The study identified a previously unknown pathway that causes adverse cardiovascular events due to…

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Changes to academic foundation jobs spark concern

Academic and doctor representative groups are concerned about sudden changes to the allocation of academic foundation jobs for 2025. The UK Foundation Programme Office announced that recruitment into specialized foundation programs in England, Scotland, and Northern Ireland will be incorporated into the main allocation process. This system, already in place in Wales, allows doctors to…

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Health care inequities behind shorter life spans for Inuit from Nunavik, Quebec, with lung cancer

Inuit people living in northern Quebec’s Nunavik region are dying earlier from lung cancer than Montreal residents being treated at the same cancer center in Montreal, according to a new study published in the Canadian Medical Association Journal. All Nunavik residents are treated at McGill University Health Center (MUHC) in Montreal due to limited resources…

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