Researchers from the DZD found that after weight loss, individuals with overweight and obesity showed an increase in the protein Kallistatin in subcutaneous white adipose tissue. This protein has potential therapeutic benefits for those with obesity and type 2 diabetes. Clinical studies revealed that obese individuals have lower levels of Kallistatin, which plays a role…
Vaccinations provide lifetime protection against diseases like hepatitis B, rotavirus, diphtheria-tetanus-pertussis, Haemophilus Influenzae Type B, polio, MMRV, hepatitis A, and flu. The vaccines are given according to a schedule starting at birth and continuing into childhood, usually before school begins. Side effects of vaccines are mild and infrequent, with soreness at the injection site and…
The addition of pembrolizumab to concurrent chemoradiotherapy for high-risk locally advanced cervical cancer does not harm quality of life, according to patient-reported outcome analyses from the KEYNOTE-A18 trial. The trial showed a 30% reduction in the risk for progression with pembrolizumab compared to placebo, with favorable overall survival trends. Patient-reported outcome instruments used in the…
Researchers from the Norwegian University of Science and Technology found that high-intensity exercise can increase levels of the hormone adiponectin in breast milk, which is beneficial for babies by protecting them against diabetes and regulating their metabolism. The study collected samples of breast milk from new mothers before and after exercise sessions, showing that intense…
Rezafungin and caspofungin are both effective treatment options for invasive candidiasis. Cookies are used on the site for analytics, advertising, and to improve the user experience. By agreeing to the use of cookies, users can benefit from these features. More information on the use of cookies can be found in the Cookie Policy and Cookie…
AI is revolutionizing healthcare by enabling gene-based precision medicine through GenAI technology, which uses advanced algorithms to match molecules with patient conditions. Pharmaceutical companies collect vast amounts of data on drugs, patient populations, and interactions to develop personalized therapies. Sales teams selling precision drugs must utilize this data to understand drug effects, interactions, and target…
In 2023, Ireland had more than 20,000 practicing physicians, with over half of them being male and one-fourth under 35 years old. The majority were generalist medical practitioners, followed by general pediatricians and psychiatrists. Many physicians had obtained their first medical qualification from countries such as Pakistan, Sudan, and the UK. The number of nurses,…
Virtual care staffing vendor Wheel has partnered with Mark Cuban’s Cost Plus Drug Company, Talkspace, and Health Gorilla to offer mental health services, affordable prescription drug pricing, and diagnostic services through its platform. The partnerships aim to provide patients with more choice, accessibility, and affordability in their healthcare journey. Wheel CEO Michelle Davey emphasized the…
Several states are considering bans on the discredited medical diagnosis of “excited delirium” from death certificates, law enforcement training, incident reports, and court testimony. California was the first state to prohibit this term in official proceedings, with other states like Colorado, Hawaii, Minnesota, and New York following suit. Families who lost relatives in encounters with…
A study found that higher levels of apolipoprotein A-I were associated with the development of giant cell arteritis (GCA) in patients. The study included data from the Malmö Diet Cancer Study and revealed that patients who later developed GCA had higher levels of apolipoprotein A-I at baseline compared to controls. Apolipoprotein B levels did not…
The content discusses the importance of positive childhood experiences (PCEs) in counteracting the negative effects of adverse childhood experiences (ACEs). The author, a psychiatrist, shares a personal story of working with a mother struggling with depression and anxiety after her child’s birth. They emphasize the need to focus on cultivating positive experiences to promote resilience…
Bernard Guratsky, a graduate of Quarry Bank Grammar School and Liverpool University Medical School, was a consultant anaesthetist at Arrowe Park Hospital from 1982 to 2005. He was proud of his Jewish and Liverpool backgrounds and played a key role in integrating staff at the new hospital. He initiated the epidural analgesia service at the…
A recent report commissioned by Swim England found evidence of a “culture of fear” in swimming clubs where children are treated more like professional athletes, prioritizing sporting performance above all else. While sport can have a positive impact on children’s well-being, issues arise when their athletic identity overshadows their identity as children. This can lead…
Researchers reviewed existing studies on post-orgasmic illness syndrome (POIS), a rare condition with limited knowledge. Symptoms include nasal congestion, fatigue, and itchiness following ejaculation, with onset within minutes and lasting up to seven days. Primary POIS occurs during puberty, while secondary develops later. Diagnosis requires specific symptom clusters and timing. Causes may involve immune hypersensitivity,…
By the time your baby is a year old, they’ll need at least 16 vaccinations, which may cause temporary pain but are crucial for protecting against dangerous childhood diseases like polio and measles. Techniques like the Five S’s (side/stomach position, shushing, swinging, swaddling, and sucking), numbing medicine, breastfeeding, and tandem shots can help reduce vaccine…
Nemolizumab, an IL-31 inhibitor, has shown good efficacy and safety in treating prurigo nodularis over 52 weeks. It has also been found effective in treating atopic dermatitis, with positive long-term maintenance data. Current treatments for prurigo nodularis are not effective or well-tolerated, making the promise of nemolizumab significant. The drug has shown sustained improvement in…
ADHD is a common neurodevelopmental disorder that can lead to negative health outcomes such as risky behaviors, mental health issues, and premature death. However, a recent study of 148,000 individuals in Sweden found that initiating ADHD medication can reduce the overall mortality risk, particularly from unnatural causes like accidents and drug overdose. The study suggests…
A study found that smoking is linked to a lower ratio of coronary volume to myocardial mass, indicating potential negative effects on heart health. The research suggests that smoking may be associated with reduced blood flow to the heart muscle, which could increase the risk of cardiovascular disease. This insight highlights the importance of quitting…
The HIMSS conference in Orlando brought together healthcare technology leaders to discuss and network. Google Cloud unveiled new clinical generative AI tools to help healthcare organizations better utilize their data. GE HealthCare and Mass General Brigham are integrating foundation models into their AI research to accelerate the development of healthcare AI tools. Philips and AWS…
St James’s Hospital in Dublin has received prestigious European recognition for their department of cardiothoracic surgery, caring for over half of lung cancer patients in Ireland. The hospital has the largest thoracic surgical oncology program in the country and has seen improved survival rates for lung cancer patients. The accreditation by the European Society of…
A study published in Chest found that critically ill COVID-19 patients are at increased risk for hospital-acquired infections (HAI), including ventilator-associated pneumonia (VAP) and bloodstream infections caused by multidrug-resistant bacteria. The study included 774 patients with severe COVID-19, with 47% developing a total of 759 HAIs, 35% of which were caused by multidrug-resistant bacteria. Patients…
AI-enabled virtual care assistants are changing patient care, but providers need to build trust as technology advances. Northwell Health and Providence Health have been using chatbots to improve patient experience, reduce readmissions, and answer administrative questions. It is important to ensure that AI algorithms are functioning correctly and that conversations with chatbots are meaningful and…
The content discussed in the podcast includes the beginning of the general election campaign for president, where health care is a critical issue, especially with Trump considering cuts to Medicare and Social Security. The panelists also talked about the cybersecurity breach at Change Healthcare, impacting medical billing across the industry. Additionally, the discussion covered Republican…
At the Hawaiian Eye 2024 conference, Dr. Richard S. Davidson discussed the importance of capsular tension rings (CTRs) in cataract surgery. He highlighted that CTRs can act as a safety net during challenging cases, making them a valuable tool for ophthalmologists. Davidson emphasized the significance of knowing when to use CTRs and ensuring that they…
Researchers and scientists argue that our understanding of sex is still primitive and outdated. They suggest that “sex” should not be the primary variable in research, but rather measurable factors like the presence of a uterus, hormone levels, and genetics. Using sex as a proxy for specific variables can lead to inaccuracies in research, such…
Fayek Dimitri Salama was a thoracic surgeon born in Cairo, who trained in the UK and worked as a consultant in Nottingham until his retirement. He obtained his medical degree from Ain-Shams Medical School and specialized in thoracic surgery. He trained as a registrar in various hospitals in the UK, including Hawkmoor Hospital, Broomfield Hospital,…
Researchers have developed a wireless, ultrathin pacemaker powered by light that eliminates the need for batteries and operates like a solar panel. This innovative design conforms to the heart’s contours and can precisely stimulate multiple areas of the heart using light-generated electrical signals. The pacemaker is thinner than a human hair, can be implanted without…
The MYCN oncoprotein is implicated in various human cancers, including high-risk neuroblastoma, making tumors less responsive to immunotherapy. Boston University researchers found that MYCN increases levels of the signaling molecule CKLF in neuroblastoma cells, suppressing anti-tumor immune responses and promoting aggressiveness. Studying experimental models and patient samples, they aim to develop effective immunotherapeutic strategies to…
Stretching is important for maintaining flexibility as you age and can help prevent muscle tightness and injury. The American College of Sports Medicine recommends stretching major muscle groups at least two times a week for 60 seconds per exercise. It is not necessary to stretch before or after a workout, but it is beneficial to…
The FDA has granted accelerated approval for lisocabtagene maraleucel (liso-cel) for adults with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). This CD19-directed chimeric antigen receptor (CAR) T-cell product is the first CAR T-cell therapy approved for this purpose. The approval follows successful results from the TRANSCEND CLL 004 study, where…
A study found a link between a donor’s pre-donation diet and allergic transfusion reactions (ATRs) in recipients, especially children. ATRs can occur in up to 2% of blood transfusions, posing life-threatening risks. Researchers discovered allergens from a donor’s pre-donation diet could induce ATRs in recipients with food allergies. The study involved blood samples from children…
49 district hospitals in Rajasthan will soon have dedicated geriatric wards to cater to the healthcare needs of elderly patients. This initiative aims to provide specialized care and support for older individuals, considering their unique medical requirements. The establishment of these wards is a positive step towards improving the quality of healthcare services for senior…
Antibody drug conjugates (ADCs) combine a cancer-killing drug with an antibody targeted to deliver the therapy directly to a tumor. Tubulis, a startup company, is working to improve on current ADC designs by developing technologies that enhance stability and target specificity. Tubulis has secured €128 million in funding to support its research and is moving…
An Irish-US cancer collaboration delegation has celebrated its twenty-fifth anniversary by meeting with the US Congressional Cancer Caucus to highlight the significant impacts in cancer research and care. The partnership between Ireland, Northern Ireland, and the US National Cancer Institute has led to increased research quality and quantity, saving thousands of lives and improving the…
A study published in Psychological Medicine found that veterans with pre-existing psychiatric disorders have an increased risk for long COVID, especially among younger individuals and those with stress-related disorders. Long COVID refers to COVID-19 symptoms persisting beyond 3 months, with overlapping symptoms like fatigue and cognitive impairment. The study looked at health records from over…
AI-driven dermatology platform Cureskin secured $20 million in Series B funding led by HealthQuad with participation from JSW Ventures, Khosla Ventures, and Sharrp Ventures. The funds will enhance AI capabilities and expand solutions, following a $5 million Series A round. Having treated 1.5 million customers, mostly from tier 2 and 3 cities, Cureskin aims for…
Amy Stelly, an advocate living near the Hunter’s Field Playground in New Orleans, is fighting to dismantle the Claiborne Expressway due to noise and pollution concerns. The highway, built in the 1960s, divided Black communities and caused economic decline. Stelly’s group proposed a plan to remove the expressway, but the federal government denied it. They…
Virtual Vision Health has enhanced its Virtual Eye Pro headset with new features including pupillography, color vision testing, and live eye streaming. These additions allow for better diagnosis of eye diseases and improved monitoring during visual field tests. The company is also working on further enhancements to the technology. Bill Shields, the global vice president…
During the pandemic, real estate developers in Greater Boston shifted their focus to life-science laboratories as the future of cities became uncertain with white-collar workers staying home. Biotech companies, like Moderna, thrived and investors saw them as a lucrative opportunity. Money poured in from venture capitalists, the stock market, and the National Institutes of Health,…
In a paper by Kearney et al. published in BMJ, the name Charalambos P Charalambous was corrected in the ARTISAN collaborators list. The corrected name was included in the publication with the reference (BMJ 2024;384:e076925, doi:10.1136/bmj-2023-076925). Source link
Short-term very low calorie diets are safe for teenagers with moderate to severe obesity when closely monitored by an experienced dietitian, according to new research. These diets, which typically involve consuming ≤ 800 calories per day with meal replacements to ensure essential nutrient requirements are met, can be an acceptable way for adolescents to lose…
Researchers at the University of Minnesota found that non-invasive brain stimulation can change brain mechanisms related to human behavior, potentially leading to new therapies for brain disorders. Published in Nature Communications, the study used transcranial alternating current stimulation to modulate brain activity, showing neural phase precession where brain activity gradually changes over time due to…
Many U.S. children and teens are not receiving all necessary vaccinations due to lack of information, socio-demographic disparities, and mistrust in science. HPV vaccination rates remain low despite the vaccine’s effectiveness in preventing HPV-associated cancers. The CDC reports low rates of HPV vaccination, as well as concerns about parents skipping the MMR vaccine, leading to…
A recent study found that a cell-free DNA blood test aimed at detecting abnormal DNA signals in people with an average risk of colorectal cancer (CRC) was successful in detecting most cases of CRC in confirmed patients. The blood test had a sensitivity of 83% for CRC and 90% specificity for advanced neoplasia, but only…
Researchers conducted an observational study to investigate if food choices affect sleep quality. They found that total protein intake did not significantly impact sleep quality, but plant protein was associated with better sleep compared to animal protein. Participants who consumed processed red meat and poultry had worse sleep quality, while those who ate dairy and…
Junior doctors at VIMSAR are on strike due to pending demands, impacting medical services at the hospital. The strike has been ongoing as doctors demand their demands to be met. This has led to disruptions in medical services at the hospital, affecting patients’ access to care. The doctors are adamant in their stance, continuing the…
Hackensack Meridian Health CEO Robert Garrett discussed the potential of AI in building healthier communities during a keynote address at the HIMSS conference in Orlando. He emphasized the need for healthcare organizations to use AI to address priorities such as increasing access to care, improving patient outcomes, advancing health equity, and addressing climate change. Garrett…
A new study published in The Lancet Neurology reveals that more than 43% of the world’s population, around 3.4 billion people, have a neurological condition. This makes neurological conditions the leading cause of ill health and disease globally. The global burden of neurological conditions has increased by 18% since 1990, surpassing cardiovascular diseases as the…
AstraZeneca is conducting a phase 3 trial on its Breztri Aerosphere inhaler therapy for COPD patients with elevated cardiopulmonary risk. The therapy combines budesonide, glycopyrrolate, and formoterol fumarate and is approved for COPD maintenance treatment by the FDA. The THARROS trial aims to assess its efficacy in reducing severe cardiopulmonary events in COPD patients at…
Hydration goes beyond just drinking water, delving into cellular hydration for optimal health and wellness. Cellular hydration refers to the ability of cells to hold water, impacting everything from skin health to physical performance and cognitive function. Cellular hydration serums penetrate deeper layers of the skin, providing essential moisture to cells. Achieving optimal cellular hydration…