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Stem cell study shows how gene activity modulates the amount of immune cell production in mice

Researchers have discovered that some genes are associated with higher, better balanced production of immune cells in mice. As people age or become ill, their immune systems become less effective. Hematopoietic stem cells (HSCs) production of immune cells varies based on specific genes. The scientists identified nearly 40 genes that relate to immune cell production…

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Substance Abuse Ups DKA Readmission Risk in Type 1 Diabetes

A study conducted at a large county hospital in Texas found significant associations between readmission with diabetic ketoacidosis (DKA) in people with type 1 diabetes (T1D) and both substance abuse and incarceration. The study identified 243 T1D patients admitted with a DKA diagnosis, with 64 having multiple admissions. Substance use disorder was identified in 40.3%…

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Find Comfort And Embrace Pain-Free Steps

Plantar fasciitis is a foot condition that causes inflammation of the plantar fascia, leading to stabbing heel pain. Choosing the right shoes with arch and heel support, cushioning, orthotic-friendly design, and lightweight comfort can provide relief. For men, slip-on options like Gecko Man, ITAZERO, Heel That Pain, XPACS, and OrthoComfoot offer stylish comfort. Women can…

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Key Trends from the 2024 J.P. Morgan Healthcare Conference

The J.P. Morgan Healthcare Conference in 2024 highlighted the potential for a healthcare revolution driven by innovation and necessity. The emerging biopharma space is experiencing a surge of innovation, resulting in promising therapies for previously untreatable illnesses. The complex Medicare landscape is being navigated with the help of data-driven solutions, ensuring access to necessary care….

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Citzens’ Assembly recommends health-led approach to drug use

A report with 36 recommendations from the Citizens’ Assembly on Drugs Use has been submitted to Oireachtas for consideration. The recommendations include a health-led approach to drug use, introducing a comprehensive health-led response to possession of drugs for personal use, greater funding for services at national and local levels, and stronger oversight and accountability at…

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Reinforce self-care on individual, system levels for clinicians to ‘flourish’

Stacy A. Ogbeide discusses the importance of self-care and wellness for healthcare professionals, especially in the post-COVID era. She emphasizes the need for the healthcare system to support practice changes that create a more enjoyable work environment for clinicians. This includes making electronic medical records more user-friendly and utilizing artificial intelligence to reduce documentation. Ogbeide…

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MS: Life Tips for Women

At 27, Julie Stamm was diagnosed with multiple sclerosis in the midst of her finance career. Now 42, she advocates for others with MS and authored a children’s book. She balances motherhood and symptoms with fun activities and empowering language. Director Mary Rensel stresses that medication, nutrition, and social connections are key to living with…

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FDA Expands Dupilumab for EoE to Younger Children

The FDA has approved dupilumab for the treatment of eosinophilic esophagitis (EoE) in children aged 1-11 years and weighing ≥ 15 kg. Dupilumab is the first and only medicine approved for this use. EoE is a chronic inflammatory disorder that damages the esophagus, causing difficulty swallowing and eating. The approval is based on results from…

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COVID-19 During Pregnancy Triples Odds Of Respiratory Illness In Children; Risk Lower In Vaccinated Expectant Mothers: Study

A recent study found that babies born to women infected by COVID-19 during pregnancy are three times more likely to develop respiratory illness. The risk is significantly lower when mothers are vaccinated before getting infected. Uninfected children exposed to the virus during pregnancy have also shown increased reports of respiratory distress. Research published in Nature…

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AWS to Infuse Another $20M Into Its Health Equity Program

Amazon Web Services (AWS) is adding $20 million to its health equity initiative, bringing its total investment to $60 million. The program aims to address health disparities highlighted by the pandemic. AWS has already distributed more than $30 million to 28 countries and partnered with 230 organizations. Their priorities include increasing access to quality health…

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Treatment De-escalation Not Effective in Metastatic CRC

In the phase 3 ERMES study, treatment de-escalation was found to be ineffective in previously untreated, metastatic colorectal cancer (CRC) patients. The study compared the effectiveness of de-escalated treatment with FOLFIRI/cetuximab until progression. However, de-escalated treatment did not meet the noninferiority endpoint for progression-free survival, with a median PFS of 10.0 months compared to 12.2…

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FDA Warning: Prolia | Medical News Bulletin

Patients with chronic kidney disease who use Prolia are at higher risk of developing dangerously low calcium levels, known as hypocalcemia. This can be particularly dangerous for patients undergoing dialysis or with mineral and bone density disorder. The FDA advises patients to contact their doctor to discuss the best medication regimen and be aware of…

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Contributed: ​​AI integration in patient diagnostics: revolutionizing healthcare in 2024

In 2023, the healthcare sector experienced a transformation due to the integration of artificial intelligence (AI) in patient diagnostics, leading to increased efficiency, accuracy, and personalization. AI-driven diagnostics revolutionizes how medical professionals approach diagnosis by analyzing patient data swiftly and aiding in identifying diseases at early stages. AI-driven diagnostic tools are being used in interpreting…

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The FTC Escalates Biden’s Fight Against Drug Prices

The Federal Trade Commission is taking aggressive action against anticompetitive practices in the healthcare industry. It has issued stricter guidelines to prevent hospital mergers and investigated practices in the drug supply chain. The FTC challenged the validity of over 100 drug patents listed in the FDA’s “Orange Book,” which can delay approval for generic competitors….

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Familial SCAD linked to aggregation of common genetic variants

Research has shown that high concentrations of common genetic variants within families are associated with an increased inherited risk for spontaneous coronary artery dissection (SCAD). Rarer genes associated with inherited connective tissue disorders were not found to be associated with SCAD risk. The study was based on a cohort of 1,352 genotyped individuals, including healthy…

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Parkinson’s study, Gilead, CG Oncology

The article discusses various developments in the biotech industry, including the challenges faced by venture capitalists, Gilead Sciences’ investment in oncology, an upcoming IPO for an obesity-related company, and new research in Parkinson’s disease treatments. It also mentions other relevant news and offers readers the option to sign up for a biotech newsletter. The industry…

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Why Do DMARDs Take Time to Work for RA?

Disease-modifying antirheumatic drugs (DMARDs) are used to treat rheumatoid arthritis (RA), but the time it takes for them to be fully effective varies depending on the type used. They target inflammation and work with the immune system to slow down or stop the disease, ultimately minimizing joint damage. Common conventional and biologic DMARDs used for…

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New ACG Guideline Offers Recommendations for ALD

The new clinical guidelines from the American College of Gastroenterology advise people with obesity, hepatitis C or B virus infections, or a history of gastric bypass to avoid alcohol to prevent alcohol-associated liver disease (ALD). Alcohol use disorder (AUD) should be treated with behavioral interventions and pharmacotherapy. The rising incidence of alcohol use has led…

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Dealing With Menopause Symptoms? Cold Water Swimming Could Alleviate Anxiety, Mood Swings And Hot Flushes

Cold water swimming has been found to alleviate symptoms associated with menopause, such as hot flushes, anxiety, and mood swings. A study surveyed 1,114 women and noted that cold water swimming provided physical and mental health benefits for menopausal women. The activity was found to relieve symptoms, improve mood, and reduce stress. Additionally, it offered…

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Medically, you might be interested in…

Dr. Ray O’Connor compiles series on latest clinical studies from around the world. A study in Sweden found that Covid-19 vaccination before infection reduces the risk of post-Covid condition (PCC) with vaccine effectiveness of 73%. Ritonavir-boosted nirmatrelvir and molnupiravir are effective in non-hospitalized Covid-19 patients. A study in France suggests immediate public health action is…

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AI identified as a top risk for healthcare

A report by Kodiak Solutions identified AI and new technologies as among the top five management risks for healthcare providers in 2024, alongside financial performance, competition, workforce, and cybersecurity. The benefits of AI tools must be weighed against the costs and workforce challenges of implementing and managing them. These tools promise greater efficiency, quicker diagnoses,…

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Stop Using the Medicine Cabinet. Oh, and Now Clean It Out

Properly storing and disposing of medications is crucial for everyone’s safety. Medications stored in bathroom cabinets are exposed to high humidity and temperature fluctuations, leading to faster degradation. Household medications are often not stored properly and can be accessible by young children or individuals struggling with substance use. Medications past their expiration date may still…

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Pandemic Left Obesity Legacy Among School Children

Lockdown measures during the COVID-19 pandemic in England caused a significant increase in obesity and overweight cases in primary school children, particularly those from deprived areas, according to researchers at the University of Southampton. Data from children aged 4-5 and 10-11 revealed a prevalence increase in overweight and obesity during the pandemic, with long-term healthcare…

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Can Chocolate-Coated Insulin Pills Replace Needles? Animal Study Shows Promising Results For Diabetes Patients

Researchers from the University of Tromsø have developed an insulin pill wrapped in a protective coating that can be swallowed, solving the problem of insulin breaking down in the stomach. This pill, when combined with sugar-free chocolate, delivers insulin directly to the liver when blood sugar levels are high, reducing the risk of hypoglycemia. The…

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Dance interventions potent tool for managing overweight and obesity

Dance interventions have been found to be highly effective in managing overweight and obesity. Research has shown that dance can help individuals achieve and maintain a healthy weight by providing a fun and engaging form of physical activity. Additionally, dance interventions have been shown to improve overall physical fitness, body composition, and psychological well-being. By…

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Technology as a Cure: Alleviating Clinician Burnout, Empowering Pharmacists to Fill Care Gaps This Cold and Flu Season

Clinicians, including doctors, nurses, and pharmacists, are experiencing high levels of burnout due to factors such as high patient volumes and inadequate support systems. This burnout is contributing to shortages of primary care providers. However, there is an opportunity for pharmacists to play a larger role in providing patient care, including administering vaccines and managing…

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