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Emotional demands and confrontation in person-contact roles linked to heightened type 2 diabetes risk

, 2025-06-24 22:30:00 Credit: Unsplash/CC0 Public Domain The emotional demands and confrontation inherent in person-contact roles, involving direct face-to-face or voice-to-voice interaction with external parties, are linked to a heightened risk of type 2 diabetes, suggests research published online in Occupational & Environmental Medicine. And inadequate social support from managers and colleagues at work seems…

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5 takeaways from health insurers’ new pledge to improve prior authorization

, 2025-06-24 19:37:00 Nearly seven months after the fatal shooting of an insurance CEO in New York drew widespread attention to health insurers’ practice of denying or delaying doctor-ordered care, the largest U.S. insurers agreed Monday to streamline their often cumbersome preapproval system. Dozens of insurance companies, including Cigna, Aetna, Humana, and UnitedHealthcare, agreed to…

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Blood-Based KRAS Testing Fails in Ovarian Cancer

, 2025-06-24 20:33:00 Blood-based circulating tumor DNA (ctDNA) testing has proven to be insufficient for detecting KRAS mutations in patients with low-grade serous ovarian cancer (LGSOC), according to a study. The findings of the new research suggest that treatment decisions should continue to rely on traditional tumor tissue analysis rather than liquid biopsies for this…

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Nektar’s Novel Eczema Drug Meets Trial Goals, But Differentiation From Dupixent Remains Unclear

Frank Vinluan , 2025-06-24 19:26:00 A Nektar Therapeutics drug has met the skin clearance goals of a closely watched mid-stage clinical trial in atopic dermatitis. While these preliminary results bring validation to the therapy’s novel approach to the immune response driving the disease, analysts note the market for atopic dermatitis drugs is crowded and it’s…

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Ollie the therapy dog brings joy to young patients

Editorial Staff , 2025-06-24 07:30:00 Meet Ollie, the first four-legged team member in the Paediatric Unit at University Hospital Galway (UHG). Every Thursday after a thorough brushing and grooming, the eight-year-old Malshi puts on his Irish Therapy Dog uniform and trots through the doors of the Paediatric Unit at UHG, where his calming and comforting…

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PD-L1 Did Not Predict Immunotherapy Benefit in CC

, 2025-06-24 17:51:00 Findings of the BEATcc trial suggest PD-L1 status is not a reliable biomarker for guiding immunotherapy selection in patients with recurrent or metastatic cervical cancer, potentially simplifying treatment decisions for clinicians managing this patient population. A post-hoc analysis of the phase 3 trial demonstrated that the addition of atezolizumab to chemotherapy plus…

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New method aims to bring novel Alzheimer’s treatments to patients sooner

Michael McHale , 2025-06-24 07:31:00 Irish researchers develop mapping model that can compare results from multiple Alzheimer’s studies Irish researchers have helped develop a first-of-its-kind method for comparing research findings into potential new treatments for Alzheimer’s to improve outcomes for patients with the disease. The research and scientific community have seen significant developments in recent…

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Appointment of FDA critic Vinay Prasad to senior role in agency prompts departures

Mun-Keat Looi , 2025-06-24 15:16:00 Vinay Prasad—the controversial head of vaccine regulation at the US Food and Drug Administration (FDA)—has been named FDA chief medical and scientific officer.1 Traditionally separate roles, his new position—in addition to his heading the Center for Biologics Evaluation and Research—grants authority across all regulatory centres and expands his influence as…

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MHRA Approves Serplulimab for Extensive-Stage SCLC

, 2025-06-24 14:20:00 The Medicines and Healthcare products Regulatory Agency (MHRA) has approved serplulimab  (Hetronifly, Henlius) to treat adults with extensive-stage small cell lung cancer (ES-SCLC).  Serplulimab is the UK’s first licensed anti-PD-1 monoclonal antibody for this aggressive form of lung cancer. It is indicated for adults with untreated ES-SCLC, where the disease has spread…

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Jeremy Griffith Reveals the Biological Cause of Emotional Turmoil

, 2025-06-24 06:57:00 In recent years mental health has become a global concern with rising rates of anxiety, depression, and emotional distress affecting individuals across all demographics. While therapeutic techniques and neuroscientific models continue to offer valuable support, some researchers argue that we’re missing a deeper explanation for why so many people feel fundamentally insecure…

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From Data Silos to Integrated Care: Driving Provider Engagement

wlim , 2025-06-24 15:00:00 Too often, communication between payers and providers falls apart, and workflows become a tangled mess. But it’s more than a minor annoyance; it holds providers back and puts patient care at risk. Connected workflow solutions offer a practical fix to these problems. They consolidate scattered data, reduce paperwork burdens, and deliver…

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Common pregnancy complications may signal future stroke risk

Editorial Staff , 2025-06-24 07:32:00 Common events like preterm delivery or a newborn with a low birth weight could act as early indicator for cardiovascular problems, research finds Women who experience complications during pregnancy face a higher risk of stroke in the following decades, according to research published today. The study, which included data on…

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How good are hearing test apps?

Dr Anthony Onunga , 2025-06-24 14:35:00 Monitoring our hearing health has gone mobile, but how reliable are these home hearing test software applications? Can hearing test apps really detect hearing loss accurately?  A team of audiology experts out of Alberta, Canada, set out to test the tests with some ear-opening results. Were the apps any…

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Readout Newsletter: Compass, Nektar, Centivax, Curevo

Meghana Keshavan , 2025-06-24 14:11:00 Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Morning! Today, we talk about the readout of Compass Pathways’ psilocybin trial for major depressive disorder, see more vaccine concern and turnover at the FDA, and report from the…

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Doctors back GPs who refuse to follow “ludicrous and unsafe” hospital prescribing practices

Rebecca Coombes , 2025-06-24 11:11:00 BMA representatives have voted to support GPs who refuse to prescribe medicines for hospital patients unless the GP has been properly informed and the treatment has been started and stabilised in secondary care. Representatives also backed GPs who reject initial prescriptions from hospital staff who are not qualified to prescribe,…

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Gene editing treats smooth muscle disease in preclinical model

, 2025-06-24 14:04:00 Base editing, a gene editing technique that swaps one “letter” of the genetic code for another, successfully converted aorta-derived smooth muscle cells carrying a mutation in the ACTA2 gene (center) to healthy cells (right) that matched the form and function of the normal aorta (left). Credit: Circulation (2025). DOI: 10.1161/CIRCULATIONAHA.125.074218 Using gene…

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Malaria protein plays dual role in immune evasion and activation

, 2025-06-24 13:49:00 Researchers from The University of Osaka find that a protein expressed on malaria-infected red blood cells both hides it from the immune system and activates cells to destroy it, making it a promising target for vaccine development. Malaria is a life-threatening disease affecting people globally. It is spread by mosquitoes carrying Plasmodium…

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PROSPER Together Founder Urges a Shift Toward Community Connection

, 2025-06-24 06:58:00 For decades, the conversation around suicide prevention has been largely dominated by clinical procedures and emergency interventions. But Dr. Kent Corso, a clinical psychologist and founder of PROSPER Together, believes it’s time to shift that narrative and the responsibility back to where it belongs: the community. Dr. Corso, whose organization partners closely…

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Consulting room to let – Dublin 2

brendan , 2025-06-24 10:04:00 Spacious and airy consulting room to let in Medical Practice. Prime location in Dublin 2, situated at Leeson Street Bridge, accessible by all major transport links. Room area is 4.13m x 4.27m, 18.48 sq.m. with stunning views over the Grand Canal. View by Appointment only – contact – adelaidepractice@gmail.com or +353…

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Nuvalent’s targeted lung cancer drug shrinks tumors

Matthew Herper , 2025-06-24 10:32:00 The biotech firm Nuvalent said Tuesday that new data indicate its targeted drug zidesamtinib could help patients with a rare form of lung cancer that has failed other treatments. For 1% to 2% of patients with non-small cell lung cancer, tumors test positive for alterations in a gene called ROS1….

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Can monoclonal antibodies effectively treat malaria? Scientists say the answer is a resounding ‘yes’

, 2025-06-24 11:00:00 Credit: Pixabay/CC0 Public Domain Monoclonal antibodies provide protection against a wide range of infectious microbes, and now, in a series of elegant laboratory experiments, scientists have uncovered how a pair of these lab-engineered molecules fight malaria. The newly developed antibodies have arrived at a critical time. Gains against mosquitoes in the years-long…

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Probiotics remain potent in simple plant-based drinks

, 2025-06-24 10:44:00 In a first-of-its-kind test, scientists show that non-encapsulated probiotics can thrive in fruit and vegetable juices, staying fresh, flavorful, and functional from shelf to sip. Study: Developing Novel Plant-Based Probiotic Beverages: A Study on Viability and Physicochemical and Sensory Stability. Image credit: Aninka Bongers-Sutherland/Shutterstock.com Probiotics have soared in popularity because of their health benefits….

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Head-to-Head Trial Finds Winner for CRSwNP With Asthma

, 2025-06-24 10:41:00 Dupilumab significantly outperformed omalizumab in reducing the size of nasal polyps and improving sense of smell in adults with severe chronic rhinosinusitis with nasal polyps (CRSwNP) and coexisting asthma, according to the head-to-head EVEREST phase 4 biologics trial. The study is the first to demonstrate the superiority of dupilumab over omalizumab across…

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A Hospital Group Pioneers Life-Changing 3D-Printed Implants

, 2025-06-24 06:59:00 Vinmec Healthcare System, a leading private hospital group in Vietnam, is transforming bone cancer care with personalized 3D-printed implants, offering new hope to patients previously facing amputation or lifelong disability. In a global first, eight-year-old Tran Minh Duc received a fully 3D-printed, growth-adaptive titanium femur after being diagnosed with aggressive osteosarcoma. Multiple…

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The Medicaid Reckoning: Era of Fiscal and Policy Flux

Adam S. Herbst , 2025-06-23 13:27:00 Medicaid today stands at the center of one of the most complex challenges in American healthcare: how to preserve a program that is financially massive, legally entrenched, and socially indispensable, while also subject to continuous political debate and structural uncertainty. It is no longer enough to describe Medicaid as…

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Push To Move OB-GYN Exam Out of Texas Is Piece of AGs’ Broader Reproductive Rights Campaign

Annie Sciacca , 2025-06-24 09:00:00 Democratic state attorneys general led by those from California, New York, and Massachusetts are pressuring medical professional groups to defend reproductive rights, including medication abortion, emergency abortions, and travel between states for health care in response to recent increases in the number of abortion bans. The American Medical Association adopted…

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