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Complications After Prostate Cancer Treatment

A cohort study compared prostate cancer patients with a control group and found that those treated for prostate cancer had higher rates of complications, including urinary and sexual issues. Radiotherapy was associated with increased risks for bladder cancer and radiation-specific complications. The study followed 29,196 participants over a median of 10.2 years and analyzed ten…

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Breakthrough in HWE reaction offers pathway for anti-cancer drug development

The Horner–Wadsworth–Emmons (HWE) reaction is crucial in organic chemistry for creating conjugated carbonyl compounds used in various industries. Improving HWE reactions is a focus of research, with potential applications in developing anti-cancer compounds. Tokyo University of Science researchers have developed a highly selective HWE reaction method using a magnesium phosphonoenolate intermediate, allowing for isolated active…

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Are Food Emulsifiers Associated With Increased Cancer Risk?

The consumption of certain food emulsifiers has been linked to an increased risk of certain cancers, particularly breast and prostate cancer, according to a large cohort study. Ultraprocessed foods, which make up around 30% of energy intake in France, often contain these emulsifiers. The study found that emulsifiers may alter gut microbiota and lead to…

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Here’s how we overcome the GP shortage

Terence Cosgrave , 2025-06-20 07:30:00 Retaining newly qualified and established GPs is critical, writes Terence Cosgrave Ireland is confronting a significant shortage of general practitioners (GPs), with the number of clinically active GPs failing to keep pace with a growing and ageing population. According to Medical Council data, the GP workforce peaked at over 4,800…

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Popular diabetes and obesity drugs also protect kidneys, study shows

A comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists shows significant benefits in kidney and cardiovascular outcomes for individuals with and without diabetes. GLP-1 receptor agonists are known for treating diabetes and obesity by mimicking glucagon-like peptide 1 hormone actions. A meta-analysis of 11 clinical trials involving over 85,000 participants confirmed a 19% reduction in…

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Can Curing Infections Help Prevent Cancer?

, 2025-04-25 10:52:00 The session titled “Defeating Cancer by Curing Infections” at European Society of Clinical Microbiology and Infectious Diseases Global 2025, held in Vienna, Austria, was led by Catharina Alberts, PhD, from the World Health Organization’s International Agency for Research on Cancer, and Francesco Negro, MD, emeritus professor, formerly at the Department of Medicine…

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AI tools could prevent maternal heart-related deaths

, 2025-04-30 02:28:00 Every year, some mothers die after giving birth due to heart problems, and many of these deaths could be prevented. The ability to screen for heart weakness before pregnancy could play a crucial role in identifying women who may need additional care to improve pregnancy outcomes. Mayo Clinic researchers, led by Anja Kinaszczuk, D.O., and Demilade…

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Salvo Health secures $5M for digital gastrointestinal care

Salvo Health, a digital gastrointestinal care startup, recently closed a $5 million Seed Prime round led by City Light Capital and Human Ventures. The company’s existing investors, including Torch Capital, Threshold Ventures, and Felicis Ventures, also participated in the round. Salvo Health offers a virtual clinic for chronic gastrointestinal and metabolic liver issues, providing wraparound…

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Heart transplant recipient’s journey: From patient to advocate

Glen Kelley, a heart transplant recipient, shared his journey at the ISHLT conference in Prague. After battling cancer and heart disease, he received two transplants and faced multiple health challenges. Despite this, Kelley had a successful career and transitioned to a patient advocate. He dedicated himself to supporting others dealing with heart disease and now…

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Eating Disorders are Highly Prevalent Among Adolescents Seen in Epilepsy Clinics

New research presented at the American Epilepsy Society Annual Meeting in 2023 found that intellectually healthy adolescents seen in epilepsy clinics have a high prevalence of eating disorders (EDs), particularly those diagnosed with psychogenic nonepileptic seizures (PNES). The study involved a 10-year observational study of adolescents with comorbid EDs seen in epilepsy clinics and found…

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A game-changer in esophagus surveillance and interventions

In a groundbreaking advancement in gastrointestinal health, researchers from Johns Hopkins University have developed the Multifunctional Ablative Gastrointestinal Imaging Capsule (MAGIC) – a game-changer in esophagus surveillance and interventions. MAGIC combines the latest optical coherence tomography (OCT) technology with an ultracompact endoscope camera and an ablation laser, offering unprecedented capabilities in esophageal imaging and potential…

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Bristol Myers Squibb’s Sotyktu Meets Goals in Two Pivotal Psoriatic Arthritis Studies

Bristol Myers Squibb’s drug Sotyktu, originally approved for plaque psoriasis, has shown positive results in two pivotal tests for psoriatic arthritis. Expanding approval to include this condition could increase revenue for the drug. Sotykut targets the enzyme TYK2, offering patients an alternative treatment option with potentially better safety than other Janus kinase (JAK) inhibitors. The…

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New FMF Recommendations Tackle Drug Resistance and Fertility

, 2025-04-18 12:10:00 A multidisciplinary team has released new evidence-based recommendations for the management of familial Mediterranean fever (FMF). Jointly endorsed by the European Alliance of Associations for Rheumatology (EULAR) and the Pediatric Rheumatology European Society, the recommendations are the first update to the 2016 EULAR guidelines. Although rare, FMF is the most common monogenic…

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JAK1 inhibition and Anti-PD1 therapy enhance outcomes in advanced lung cancer

A small clinical trial led by the Abramson Family Cancer Center at the University of Pennsylvania Perelman School of Medicine has shown promising results by adding an anti-inflammatory drug to anti-PD1 checkpoint inhibitor immunotherapy for advanced lung cancer. The study published in Science highlighted the importance of reducing chronic inflammation while maintaining initial inflammatory responses…

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EAGLE-1 phase III trial shows

The EAGLE-1 phase III trial demonstrated that gepotidacin has the potential to be a novel oral treatment option for uncomplicated gonorrhoea. This new medication could offer an effective and convenient alternative for patients with this sexually transmitted infection. The study results suggest that gepotidacin may be a promising solution to combat the rising rates of…

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FDA Approves Nonstimulant Liquid Onyda XR for ADHD

The FDA has approved Onyda XR, a liquid nonstimulant medication for treating ADHD, making it the first of its kind. The drug can be used alone or in conjunction with stimulant medications in children aged 6 and older. Onyda XR offers a convenient option with nighttime dosing to help individuals better control their ADHD symptoms….

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Patent submission for Optimer® binders in cosmetic products

Aptamer Group plc has filed a patent application to protect recently developed Optimer binder sequences for use in fast moving consumer goods through its partnership with Unilever. The patent submission on March 28, 2024, reinforces the commercial protection of Aptamer Group’s technology in high-performance binders. The binders were developed as part of a fee-for-service project…

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Community-Acquired Urinary Tract Infection: Adverse Effects of Cotrimoxazole vs Fluoroquinolones

A study published in Infectious Diseases Now compared the treatment of community-acquired urinary tract infections (cUTI) with cotrimoxazole vs fluoroquinolones. Among 640 patients with cUTI due to Enterobacteriaceae, those treated with cotrimoxazole experienced more adverse effects and longer hospital stays compared to those treated with fluoroquinolones. The study also found that the use of broad-spectrum…

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Some lung cancer patients maintain long-term control after stopping immunotherapy

, 2025-04-18 05:16:00 Bottom line: A subset of patients with non-small cell lung cancer (NSCLC) who discontinued immune checkpoint inhibitor (ICI) therapy due to immune-related adverse events (irAEs) continued to experience long-term disease control. Journal in which the study was published: Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR) Authors:…

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Summer COVID surge isn’t cause for alarm, experts say

President Joe Biden and HHS Secretary Xavier Becerra are among the latest COVID-19 cases in the current surge, likely caused by the KP.3 and KP.2 variants of the omicron strain. These variants are not more dangerous than previous ones, with mild symptoms reported in most cases. Despite an increase in infections, hospitalizations, and deaths have…

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Infliximab Biosimilars Uptake in US Reveals Ongoing Concerns

Researchers found that uptake of infliximab biosimilars in the United States increased significantly after the third biosimilar became available in July 2020. However, Medicare prescriptions still lag behind private insurance and Medicaid. The study analyzed data from over 1100 rheumatologists from April 2016 to September 2022. By September 2022, biosimilar uptake was higher for Medicaid…

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Transgender Males Ovulate Despite Amenorrhoea

A study found that one third of 52 transmasculine individuals receiving testosterone and scheduled for oophorectomy ovulated, highlighting the importance of contraception for sexually active individuals. The study involved evaluating the ovaries of these individuals for signs of ovulatory activity, with 17 out of 52 displaying recent ovulation. The researchers noted that amenorrhea does not…

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Spinal muscular atrophy treated in utero in mice

Megan Molteni , 2025-05-14 18:18:00 Researchers have taken preliminary steps toward treating a devastating neurodevelopmental disorder, spinal muscular atrophy, with a genetic therapy delivered in the womb, before the worst damage to motor neurons can occur.  The scientists at the University of California, San Francisco, and Johns Hopkins University in Baltimore injected an antisense oligonucleotide,…

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Healthcare Moves: A Monthly Summary of Hires and Layoffs

This monthly roundup highlights recent hiring news in the healthcare industry. The Coalition for Health AI, the College of American Pathologists, Geisinger, Genuine Health Group, Optum Financial Services, StimScience, University of Florida Health, and US Radiology Specialists have all made recent executive hires. Promotions include the Arizona Department of Health Services naming Eugene Livar as…

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‘Monumental’ and ‘highly meaningful’ advances across solid tumors highlight ESMO program

The ESMO Congress recently took place in Madrid, and presidential symposium sessions highlighted upcoming new standards of care based on several groundbreaking studies. These present a potential change to clinical management for patients with urothelial cancer, lung cancer and colorectal cancer. The studies reviewed the combination of pembrolizumab and enfortumab vedotin, showing remarkable efficacy in…

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Evaluating hydronidone for the treatment of chronic hepatitis B-associated liver fibrosis

, 2025-04-18 18:57:00 Background and aims Liver fibrosis is a key process in the progression of chronic liver diseases. However, there are currently no drugs specifically designed to treat liver fibrosis. Our Phase 2 trial of hydronidone for the treatment of chronic hepatitis B (CHB)-associated liver fibrosis showed that adding hydronidone to entecavir resulted in…

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Your Diet For Healthy, Disease-Free 70’s

Summarize this content to 100 words What you eat in your 40s can be the difference between thriving or fighting disease in your 70s. While popular eating plans like the Mediterranean, DASH, and planetary diets have long been praised for their health benefits, researchers have now pinpointed a specific dietary approach that stands out for…

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A Parent’s Guide to Vaccines

Vaccinations provide lifetime protection against diseases like hepatitis B, rotavirus, diphtheria-tetanus-pertussis, Haemophilus Influenzae Type B, polio, MMRV, hepatitis A, and flu. The vaccines are given according to a schedule starting at birth and continuing into childhood, usually before school begins. Side effects of vaccines are mild and infrequent, with soreness at the injection site and…

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WuXi and Congress, Boundless Bio, etc.

Stay updated on the latest developments in the biotech industry by signing up for a newsletter. The latest biotech IPO, Boundless Bio, raised $100 million before experiencing a 9% share price drop. Congress is considering legislation that could impact Chinese life sciences companies like WuXi AppTec, which is accused of sharing American intellectual property with…

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Left Ventricular Size Predicts Dysfunction in Infant Ventricular Septal Defects

A study published in Pediatric Cardiology found that infants with elevated left ventricular internal dimensions (LVIDd) prior to ventricular septal defect (VSD) repair are at risk for postoperative left ventricular systolic dysfunction (LVSD). Postoperative LVSD is common in these patients but resolves within 9 months of surgery. The study, conducted at Arkansas Children’s Hospital, included…

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Phase Scientific secures $34M and more digital health funding

, 2025-05-20 16:47:00 Phase Scientific, a company developing urine-based diagnostics tests for early disease detection, announced it completed a $34 million Series A funding round.  A private equity fund managed by Asia-based Value Partners Group led the round, with backing from other new investors and existing global investors.  The biotechnology company’s test Phasify uses urine…

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Won’t anybody think of the doctors?

The author discusses the ongoing under-investment in healthcare in Ireland, exemplified by the Children’s Hospital debacle. The Irish Medical Organisation (IMO) recently called for the €13 billion Apple tax windfall to be exclusively invested in the healthcare sector. The author questions whether this investment in healthcare would provide the best value compared to other areas…

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MedeAnalytics, Socially Determined, Mathematica join forces

[gpt3]Summarize this content to 100 words: Texas-based healthcare data analytics company MedeAnalytics announced it is collaborating with fellow healthcare data analytics firms Socially Determined and Mathematica. The companies launched “Social Risk Insights, Measures and Outcomes,” a program built on the MedeAnalytics Heath Fabric platform launched earlier this month.  Health Fabric, which is on the Snowflake…

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