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Women’s health company Heranova Lifesciences launches with $13.5M

Boston-based healthcare company Heranova Lifesciences, focusing on women’s reproductive health, pregnancy, and menopause, has launched with $13.5 million in seed and seed+ funding. The company offers diagnostic testing and therapeutics for endometriosis, bacterial vaginosis, genetic testing, and fertility. They plan to develop non-invasive endometriosis tests and therapeutic programs for bacterial vaginosis and endometriosis with the…

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‘An Arm and a Leg’: When Hospitals Sue Patients (Part 2)

In this content, Dan Weissmann talks about the issue of hospitals suing patients who can’t afford to pay their medical bills. He discusses his conversation with Scott Purcell, CEO of ACA International, on the effects of these lawsuits on patients. The content also covers the findings of investigations into hospital bill lawsuits in Maryland, Wisconsin,…

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Study shows quick rate of C. auris contamination near colonized patients

The study found that contamination of health care environments near patients with C. auris occurs quickly, often within 4 hours of disinfection. Most C. auris carriers were found to be co-colonized with at least one bacterial multidrug-resistant organism. This highlights the need for broadly effective interventions to reduce colonization burden and environmental contamination against multiple…

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Antibiotic resistance and the global rise in human conflict

Conflict zones have caused a high spike in multidrug-resistant infections in Ukraine and Gaza. Historically, conflicts have always created perfect conditions for drug resistance. An increasing historical number of global conflicts signify that the rise of drug-resistant diseases may have been underestimated. The appearance and growth of drug resistance have mainly been driven by the…

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Understanding injuries during assisted delivery

Shree Datta, a consultant obstetrician and gynaecologist in London, UK, critiques a study by Muraca and colleagues on trauma during operative vaginal deliveries. She points out that the severity of perineal tears is influenced by ethnicity, specifically South Asian and Black women being at higher risk. Datta also emphasizes the importance of addressing maternal consent…

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Is That Hum Keeping You Up? Here’s How to Get Better Sleep

Sleep deficit is a global problem, with Omagh, Northern Ireland residents being kept awake by a persistent hum and vibration. The Worldwide Hum is only heard by 2-4% of people and is related to low-frequency noise from human or industrial sources such as traffic, ventilation systems, and airplanes. Low-frequency noise disrupts sleep, causing increased light…

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Bristol Myers Squibb to acquire RayzeBio for USD 4.1 billion

Bristol Myers Squibb announced plans to acquire RayzeBio for USD 4.1 billion. This move aligns with Bristol Myers Squibb’s strategy to expand its oncology pipeline. RayzeBio’s expertise in targeted radiopharmaceuticals for cancer treatment will complement Bristol Myers Squibb’s existing portfolio. The acquisition is expected to enhance the company’s ability to develop innovative therapies for patients…

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Unveiling the Future of Radiology: Key Trends from RSNA 2023

The RSNA 109th Scientific Assembly and Annual Meeting in Chicago focused on innovation in radiology, with discussions shaping the future of the field in 2024 and beyond. Major trends highlighted at the conference included the integration of artificial intelligence (AI) in radiology, a renewed focus on health equity, and efforts to enhance the patient experience….

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PIRA in Children With MS: Early Disease-Modifying Therapy May Offer Protection

A study published in JAMA Neurology found that children with Multiple Sclerosis (MS) are less likely to experience progression independent of relapse activity (PIRA) or relapse-associated worsening over a decade of follow-up compared to individuals with adult- or late-onset MS. However, PIRA increases rapidly in this patient population beginning in young adulthood. The study included…

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Digital health leaders on the most noteworthy events of 2023

Executives in the digital health space shared the most significant events in healthcare in 2023, including the rise of generative AI, the impact of ChatGPT, the fall of Silicon Valley Bank, and Medicaid disenrollment. The launch of generative AI, particularly ChatGPT, and the release of Apple Vision Pro were unexpected and are poised to fundamentally…

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Seven updates on ultraprocessed foods

Healio’s coverage of research on ultraprocessed foods covers the significant impact these foods have on nutrition and health. Studies have shown a link between ultraprocessed foods and conditions like obesity, cardiovascular disease, depression, and mortality. However, some experts argue that there is not yet enough evidence to support policies against their consumption. The top ultraprocessed…

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Going for a walk wasn’t really a thing 300 years ago—the Victorians turned it into a popular pastime

Walking wasn’t a popular pastime until the late 1700s. The term “pedestrianism” originally had a sporting connotation. It became a leisure activity in the 1780s, popularized by famous walkers such as Charles Dickens and the Lake poets. City streets during the 1800s were dirty and unsanitary, creating jobs for street sweepers and pure finders. These…

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Your unique microbiome may be used to improve and personalize your future medical experience

Researchers discuss using the gut microbiome in personalized medicine. Personalized medicine based on an individual’s gut microflora can overcome limitations of current approaches and provide more accurate diagnostics and treatments. Microbiome analysis has shown promise in diagnostics and treatment of diseases, and AI and machine learning can be used to analyze and predict patient responses…

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What to Expect Over the Long Term

Ulcerative colitis (UC) is a long-term illness characterized by unpredictable symptoms that come and go over time. Around half of Americans with UC are in remission, with three types of remission – clinical, endoscopic, and deep. Deep remission does not mean you are cured, and there is still a chance of future flare-ups. It is…

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FDA Expands Label for CVRx Barostim System in HF

The FDA has approved an expanded label for the Barostim neuromodulation system for patients with heart failure, based on longer-term clinical data from the BeAT-HF trial. The system is indicated for patients with class III or II heart failure with certain criteria. The device stimulates carotid baroreceptors and is implanted below the collarbone. The FDA’s…

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Unbound bilirubin, a robust predictor of acute bilirubin encephalopathy in infants

Unbound bilirubin levels can predict the likelihood of acute bilirubin encephalopathy in infants. This suggests that monitoring unbound bilirubin may help identify infants at risk for this serious condition. The article also mentions the use of cookies for analytics, advertising and site improvement, and directs readers to their Cookie Policy and Settings for more information….

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Cytokinetics Heart Drug’s Trial Data Look Competitive With BMS Med Camzyos

An experimental drug from Cytokinetics has shown promising Phase 3 results in improving heart function during exercise for patients with obstructive hypertrophic cardiomyopathy (oHCM), a rare cardiovascular disease. The drug, aficamten, demonstrated a significant increase in peak oxygen uptake compared to a placebo and had a consistent treatment effect across patient subgroups. The drug works…

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RFK Jr.’s Campaign of Conspiracy Theories Is PolitiFact’s 2023 Lie of the Year

Robert F. Kennedy Jr.’s presidential campaign is built on conspiracy theories and anti-vaccine sentiments. He has obtained significant financial backing and support based on these theories, although they have been proven to be false. Kennedy comes from an elite background, with a history of environmental advocacy before becoming focused on vaccines. His efforts to legitimize…

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Cytokinetics’ aficamten helps HCM patients in new study

Cytokinetics announced that their experimental drug, aficamten, significantly improved exercise capacity for patients with obstructive hypertrophic cardiomyopathy (HCM). The study enrolled 300 patients, and after 24 weeks of treatment, those receiving aficamten showed significant improvements in peak oxygen uptake and met the study’s primary goal. The trial also met all 10 of its secondary endpoints….

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Histone acetylation, transcription factor dynamics contribute to gene expression in brain development

Researchers have uncovered a fundamental mechanism that lets neurons know when and how to form complex connections between and among brain cells, contributing to normal brain development. The transcription factor CREB is required for the brain to learn and form memories, and its interaction with CBP stimulates gene expression during brain development. Neuronal activity increases…

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Newest Treatments for Relapsed/Refractory Multiple Myeloma

The newest treatments for relapsed/refractory multiple myeloma are discussed in the content. It is likely to cover the latest advancements in medical treatments for this condition, potentially including new drugs, therapies, or clinical trials. This information could be beneficial for patients, caregivers, or healthcare professionals seeking the most up-to-date options for managing relapsed or refractory…

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EU Seeks to Reduce the Risks for AI

The European Union is implementing stricter regulations for the use of artificial intelligence. The proposed AI Act aims to ensure AI safety while respecting basic rights and democracy. The legislation will apply to large AI companies and includes protective measures, restrictions on biometric identification systems, and bans on social scoring and certain AI technologies. There…

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Medical Bulletin 27/December/2023

The Medical Bulletin from 27 December 2023 states that the website uses cookies for analytics, advertising, and site improvement. By continuing to use the site, users agree to the use of cookies. More information can be found in the Cookie Policy and Cookie Settings. Source link

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AstraZeneca Goes With Gracell to Gain an Edge in Next-Generation Cell Therapies

AstraZeneca has acquired Gracell Biotechnologies for $1 billion, with the potential for additional payments based on regulatory milestones. This acquisition will help AstraZeneca address the challenges of cell therapy manufacturing in cancer treatment and expand into autoimmune diseases. Gracell has developed technologies to shorten manufacturing times and improve the effectiveness of cell therapies, including a…

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Carrum Health, Florida Cancer Institute partner to expand breast cancer care

Carrum Health has collaborated with Florida Cancer Specialists & Research Institute to provide employers in Florida with breast cancer care services. The San Francisco-based company offers a digital platform for self-funded employers to purchase specialty care, focusing on surgical and cancer care. Through their Center of Excellence network, Carrum highlights high-quality surgical centers across the…

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FDA approval of Vevye tops 2023 cornea articles

The top cornea-related articles on Healio in 2023 featured the FDA approval of Vevye for dry eye disease and the efficacy of azithromycin in treating meibomian gland dysfunction. Other articles included the approval of Vyznova cell therapy for bullous keratopathy and tips for navigating secondary dry eye disease. Additionally, a video perspective discussed the importance…

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Food-as-medicine programs need more research

Food-as-medicine programs that address food insecurity and diet-related chronic diseases are gaining attention, but there is little evidence of their effectiveness. A clinical trial was conducted on a program that prescribes healthy food to food-insecure patients with uncontrolled type 2 diabetes. The results showed high engagement in the program, improvement in self-reported diet, and a…

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New model links RNA editing glitch to early-stage type 1 diabetes

A study from Hebrew University’s Hadassah Medical School introduces a new model suggesting that disrupted RNA editing in pancreatic beta cells may trigger an inflammatory response similar to early-stage type 1 diabetes. This challenges the long-held belief of viral involvement and could have implications for T1D treatments and cures. This perspective offers a new insight…

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ICIs in Melanoma: Predicting Immune-related Adverse Events

A study found that routine histopathology reports on melanoma patients can help predict which patients are most likely to develop immune-related adverse events while taking immune checkpoint inhibitors. The study evaluated 511 patients and found that the presence of lymphovascular invasion and NRAS mutation were associated with increased odds of developing all-grade immune-related adverse events….

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Genicular artery embolization improves knee function for 3 months in knee osteoarthritis patients

Genicular artery embolization has been found to improve knee function in patients with knee osteoarthritis for up to 3 months. This minimally invasive procedure targets the genicular arteries that supply blood to the knee joint, reducing pain and improving overall function. By blocking these arteries, the procedure can provide relief for those suffering from knee…

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Biological Aging Process May Be Impacted by These Sleep Traits

Researchers used a case-control design with Mendelian randomization analyses to examine the link between sleep traits and biological aging risk. They found that shorter sleep duration and increased insomnia symptoms were associated with a higher risk of biological aging. These findings suggest that poor sleep habits may contribute to accelerated biological aging processes. The study…

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Andreessen Horowitz on digital health funding in 2024 and AI regulation

investment partner Jay Rughani reflected on the challenges faced in healthcare in 2023, including health worker burnout, staffing shortages, and health disparities. However, he remains optimistic about the potential of digital health and modern technology to improve efficiency and accessibility in healthcare. Rughani discussed the potential of AI in healthcare for 2024, focusing on implementing…

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AI-based tools help monitor GA progression, treatment effects

Dr. Ursula Schmidt-Erfurth discusses the use of AI-based OCT analysis for geographic atrophy at the FLORetina-ICOOR meeting. These tools help identify disease biomarkers and select patients for new complement inhibition treatments. They also allow for monitoring of treatment efficacy, providing crucial information for clinical management. Schmidt-Erfurth emphasizes the importance of this breakthrough in helping patients…

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Hospitals owned by private equity see complications spike 25%

A study published in the Journal of the American Medical Association reveals that hospitals acquired by private equity firms experience a 25% increase in adverse events compared to non-acquired hospitals. The research also suggests that all of the hospital-acquired conditions they studied increased three years after a private equity acquisition compared to control hospitals. This…

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