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Complexities of Vitamin D in CKD Require Individualization

, 2025-04-18 12:57:00 When it comes to issues of vitamin D in chronic kidney disease (CKD), core certainties include that most patients with CKD have dysregulated 25-hydroxy vitamin D (25[OH]D) and nutritional supplementation can increase those levels. Beyond that, complexities abound, with evidence fraught with confounders regarding who may or may not benefit from supplementation….

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‘Usually Only Seen in Elite Bodybuilders’

, 2025-04-18 15:20:00 A TikTok video featuring a ChatGPT response has gone viral after it declared President Donald Trump‘s reported physical results “virtually impossible,” and compared them to those of elite-level bodybuilders. In a viral TikTok video posted by @coughbuddy, ChatGPT is shown analyzing Trump’s alleged physical stats—specifically, a 215-pound weight at 6’3″—and responding that…

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HealthMed, Podimetrics partner to help high-risk patients with diabetes

, 2025-04-18 17:47:00 Podimetrics, a company that helps patients with diabetes prevent serious complications, is teaming up with HealthMed, an employee health and wellness platform. HealthMed aims to integrate Podimetrics’ SmartMat technology into its portfolio of benefits intended for large employers, hospitals and municipalities. The company also provides employee wellness and mental health programs. Podimetrics’ SmartMat…

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‘Tell That to a Diabetic’

, 2025-04-18 19:37:00 As Dr. Mehmet Oz was sworn in as head of the Medicare and Medicaid Services, he encouraged Americans to reduce drug spending by simply staying healthy. “It is your patriotic duty — I’ll say it again — the patriotic duty of all Americans to take care of themselves,” Oz said during the…

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Why One Healthcare Founder Never Took Venture Capital

Katie Adams , 2025-04-18 19:20:00 The digital health funding market has been way up and way down over the past five years. As this roller coaster starts to settle down, one thing is clear to Randy Bolyga: that the industry is shifting toward prioritizing profitability over aggressive expansion. Bolyga is the CEO of medical software…

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GLP-1 therapies show potential for treating rare genetic disorder Bardet-Biedl syndrome

, 2025-04-18 17:35:00 Credit: Monell Chemical Senses Center A Monell Chemical Senses Center study published this week in the Journal of Clinical Investigation offers renewed hope for individuals living with Bardet-Biedl Syndrome (BBS), a rare genetic disorder characterized by early-onset obesity, compulsive eating, and cognitive impairments. The Monell team and colleagues identified that GLP-1 receptor…

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Neural fingerprints reveal how teamwork and deep focus interact

, 2025-04-18 17:26:00 Summary: A collaborative study by researchers from Toyohashi University of Technology and California Institute of Technology (Caltech) introduces a groundbreaking algorithm that maps individual brain activity in a multi-dimensional space. This “neural fingerprint” reveals stable, long-term neural traits that interplay with transient brain states during social interactions. The study demonstrates that individuals…

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Dupilumab Approved for Chronic Spontaneous Urticaria

, 2025-04-18 17:06:00 The US Food and Drug Administration (FDA) has approved dupilumab for the treatment of chronic spontaneous urticaria (CSU) in patients aged 12 years and older who “remain symptomatic despite H1 antihistamine treatment,” according to a press release from the manufacturers, Regeneron Pharmaceuticals and Sanofi.  Approval follows the FDA’s request in October 2023…

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RFK Jr. Is Giving Families ‘False Hope’ By Claiming He’ll Figure Out Cause of Autism by September, Former FDA Vaccine Head Warns

, 2025-04-18 15:22:00 Dr. Peter Marks, the former top vaccine official at the U.S. Food and Drug Administration (FDA), has criticized Health and Human Services Secretary Robert F. Kennedy Jr. for giving what he called “false hope” to families by claiming that the Trump administration will identify the cause of autism by September. Marks, who…

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Medical Device Right to Repair is the Wrong Approach

Peter J. Pitts , 2025-04-18 13:55:00 Americans are becoming more familiar with the right to repair movement that is shaking up industries from agriculture to consumer electronics. The notion is that consumers should be empowered to hire whoever they want to fix their own technologies, regardless of expertise or oversight. In fact, as of 2025…

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Eli Lilly, Novo Nordisk, FDA, Makary, GSK

Meghana Keshavan , 2025-04-18 13:02:00 Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Morning! Today we talk about Eli Lilly’s stock jumping after it released new data on its GLP-1 pill, see Sanofi partner with a mysterious company, and more. A very…

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Bruker introduces nVista 2P miniature microscope

, 2025-04-18 10:48:00 Bruker Corporation today announced the launch of the nVista 2P miniature, two-photon microscope, a groundbreaking addition to the Inscopix product line for functional imaging of freely behaving animals. It leverages advanced two-photon fluorescence microscopy technology to enable high-resolution imaging at greater depths with 3D data reconstruction, providing researchers with unprecedented insights into neuronal activity. Featuring several…

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FDA Authorizes First Digital Therapeutic for Migraine

, 2025-04-18 13:29:00 The US Food and Drug Administration (FDA) has granted marketing authorization to CT-132 (Click Therapeutics), an adjunctive, first-in-class prescription digital therapeutic for the preventive treatment of episodic migraine in adults, its development company announced in a statement. The mobile smartphone app uses biological, psychologic, and behavioral approaches to target pain processing and…

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We’re reading about FDA layoffs, pharma tariffs

Ed Silverman , 2025-04-18 13:54:00 And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is still shaping up. We expect to promenade with the official mascots and catch up on our reading, and…

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Why insurance companies are denying coverage for prosthetic limbs

, 2025-04-18 12:13:00 Why insurance companies are denying coverage for prosthetic limbsPlay PBS News Weekend’s Ali Rogin spoke with KFF Health News contributor Michelle Andrews about what some people with missing limbs consider a disparity in health insurance coverage: Though a knee replacement likely would be covered, a prosthetic knee isn’t always. A prosthetic device…

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Wildfire Smoke Linked to Increase in Mental Health ED Visits

, 2025-04-18 13:21:00 TOPLINE: Exposure to fine particulate matter (PM2.5) from the 2020 California wildfires was linked to an increase in mental health-related emergency department (ED) visits within 7 days of exposure, including increases of 8% for all-cause mental health, 15% for depression, and 29% for other mood-affective disorders, a new study showed. METHODOLOGY: Data…

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When Patients Win,  Everyone Wins

Suzanne Harris , 2025-04-18 13:00:00 If someone asked if your company or product was patient-centric, you would likely respond with an enthusiastic yes. Let’s probe a bit deeper… When was the last time you asked a patient to contribute to trial design? Have you ever asked a patient to contribute to a protocol? If you’re…

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Study highlights underrepresentation of ethnic minorities in research on multiple long-term conditions

, 2025-04-18 11:18:00 New research shows that ethnic minorities are underrepresented in studies into multiple long-term conditions (MLTCs), despite being more likely to be affected. A systematic review published in the Journal of the Royal Society of Medicine found a lack of reporting on ethnicity and underrepresentation of ethnic minority groups in intervention studies to…

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Abortion Rates Stable in Canada but Spike Elsewhere

, 2025-04-18 11:12:00 Abortion rates increased substantially from 2020 to 2023 in the United Kingdom and Europe, but not in Canada, a new study found. “We are not seeing this kind of dramatic spike in abortion rates in Ontario, which has about 40% of the Canadian population,” lead author Laura Schummers, assistant professor of pharmaceutical…

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How Trump AI strategy differs sharply from Biden’s

Casey Ross and Brittany Trang , 2025-04-18 08:30:00 Casey Ross covers the use of artificial intelligence in medicine and its underlying questions of safety, fairness, and privacy. Brittany Trang, Ph.D., is a health tech reporter at STAT and writes the AI Prognosis newsletter. Follow her on Threads, Mastodon, and Bluesky. You can reach Brittany on…

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Some lung cancer patients maintain long-term control after stopping immunotherapy

, 2025-04-18 05:16:00 Bottom line: A subset of patients with non-small cell lung cancer (NSCLC) who discontinued immune checkpoint inhibitor (ICI) therapy due to immune-related adverse events (irAEs) continued to experience long-term disease control. Journal in which the study was published: Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR) Authors:…

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BMA Loses Legal Challenge Against GMC Over Associates

, 2025-04-18 09:11:00 The British Medical Association (BMA) has lost a High Court challenge against the General Medical Council over its regulation of associate professions.  The BMA took legal action last year, arguing that the GMC’s use of the term “medical professionals” to describe both doctors and associates blurred important distinctions and risked patient safety….

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And now for the science bit…

Terence Cosgrave , 2025-04-18 07:33:00 To compete with the other countries out there means a substantial investment from the Irish government in research and development, writes Terence Cosgrave I don’t think the Pope has ever described the exact length that a woman’s dress should be. The Church was very worried for a time about women’s…

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