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What’s Really Behind Those Symptoms

, 2025-04-18 09:10:00 “Defined about 30 years ago, autoimmune pancreatitis [AIP] remains a diagnostic challenge,” said Vinciane Rebours, MD, PhD, professor and head of the Pancreatology and Digestive Oncology Department, Beaujon Hospital in Clichy, France. She spoke at the Francophone Days of Hepatology, Gastroenterology, and Digestive Oncology 2025, held in Paris. The challenge lies in the…

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Human Tissue On-Demand: How 3D Bioprinting Works

, 2025-04-18 10:04:00 We’ve come a long way from the Vacanti mouse. Back in the mid-90s, Charles Vacanti and other researchers experimented with cartilage regeneration and, with the help of a biodegradable mold and bovine cells, grew cartilage the size and shape of a human ear under the skin of a nude mouse, making it…

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Opioid control laws linked to 10% drop in domestic violence cases

, 2025-04-19 09:31:00 Credit: Unsplash/CC0 Public Domain A new study led by the University of South Florida reveals opioid control policies may offer broader public health benefits, including reducing instances of domestic violence. As policymakers continue to grapple with the opioid epidemic, this study highlights the power of research to inform effective public policy. The…

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The Good, the Bad, and the Risky: New Insights on STIs

, 2025-04-18 10:07:00 At European Society of Clinical Microbiology and Infectious Diseases Global 2025, held recently in Vienna, Austria, one of the oral sessions focused on key updates regarding sexually transmitted infections (STIs). Among the presentations, two stood out due to their clinical relevance. The first, titled “Post-Exposure Prophylaxis with Doxycycline (doxy-PEP): Uses and Results…

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Science-backed exercise therapy improves low back pain

, 2025-04-18 16:29:00 Credit: Pixabay/CC0 Public Domain Research supports the effectiveness of a kinesiology-based method to treat lower back pain, say study authors working in collaboration with the National Research Council of Italy, and scientists at the Sbarro Health Research Organization under the leadership of its Founder and President, Antonio Giordano, M.D., Ph.D., Professor at…

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Patient survey reveals cautious support for AI in mammography screening

, 2025-04-18 17:52:00 The results of a large survey from a diverse patient population revealed cautious support for artificial intelligence (AI) implementation in screening mammography, according to a study published today in Radiology: Imaging Cancer, a journal of the Radiological Society of North America (RSNA). Personal medical history and sociodemographic factors influenced respondent’s level of…

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Study Reveals Racial Disparities in IBD Healthcare

, 2025-04-18 11:07:00 TOPLINE: Among individuals with inflammatory bowel disease (IBD), Asian and Hispanic American individuals had lower healthcare utilization than White American individuals, whereas Black American adults aged 65 years or older had higher use of emergency department utilization. METHODOLOGY: Although IBD is more common among White American individuals, Black and Hispanic individuals face…

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Using AI to understand how the brain processes language during real-life conversations

, 2025-04-19 03:04:00 What were you investigating? We investigated how our brains process language during real-life conversations. Specifically, we wanted to understand which brain regions become active when we’re speaking and listening, and how these patterns relate to the specific words and context of the conversation. What methods did you use? We employed artificial intelligence…

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Can a Polygenic Risk Score Help Catch More Prostate Cancers?

, 2025-04-18 11:41:00 Incorporating a polygenic risk score into prostate cancer screening could enhance the detection of clinically significant prostate cancer that conventional screening may miss, according to results of the BARCODE 1 clinical trial conducted in the United Kingdom. The study found that about 72% of participants with high polygenic risk scores were diagnosed…

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Top-Line Results Positive for Lilly’s Oral Orforglipron

, 2025-04-18 11:59:00 Orforglipron, Eli Lilly’s investigational oral glucagon-like peptide 1 receptor agonist (GLP-1 RA), achieved positive phase 3 results for both A1c and weight loss, according to top-line data released by the company. The findings came from Lilly’s ACHIEVE-1, the first of seven phase 3 trials examining the safety and efficacy of orforglipron in…

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My rare disease doesn’t even have a single name

Taylor Coffman , 2025-04-18 08:30:00 In 2022, I gave birth to a healthy baby girl and triggered a wildly violent chain of events: multiple organ failure, hemorrhaging, blood clots in many of my major organs, and a rattled medical team working tirelessly to keep me alive. For five weeks, I rotated in and out of…

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Opioid control policies linked to drop in domestic violence

, 2025-04-19 03:15:00 A new study led by the University of South Florida reveals opioid control policies may offer broader public health benefits, including reducing instances of domestic violence. As policymakers continue to grapple with the opioid epidemic, this study highlights the power of research to inform effective public policy. The research conducted by USF…

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Lack of Bladder Control Tied to Emotional Health in Kids

, 2025-04-18 12:00:00 TOPLINE: According to a new study, children with urinary incontinence (UI) had worsening emotional problems over time, and changes in emotional problems predicted the risk for UI in the future. METHODOLOGY: Researchers analysed data of 8188 children aged 6.5 to 9 years (50.7% girls) from the ALSPAC study to assess the potential…

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Non-Enhanced CT Rarely Aids Haemorrhage Detection

, 2025-04-18 12:00:00 TOPLINE: Non-enhanced CT scans were deemed helpful in only 4% of haemorrhage cases, primarily in gastrointestinal bleeding, while contributing substantially to the overall radiation exposure. An analysis of 75 patients revealed that non-enhanced CT series accounted for more than 37% of the total radiation dose. METHODOLOGY: Researchers conducted a retrospective analysis of…

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Discovery shows potential for brain aging and disease therapies

, 2025-04-18 17:16:00 Neural stem cells can develop into various types of neurons and non-neuronal cells but with aging they don’t differentiate as easily. Credit: Matthew Modoono/Northeastern University Northeastern University scientists have discovered that a protein in the human brain could potentially be used to grow new neurons in the lab and enhance brain processes…

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The dual role of microRNAs in lung cancer progression and suppression

, 2025-04-18 18:48:00 Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Despite significant advancements in diagnostic techniques, LC remains highly lethal, largely due to late-stage diagnosis and aggressive metastasis. Recent…

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Appendix Removal With Therapy May Help Maintain UC Remission

, 2025-04-18 12:00:00 TOPLINE: Among patients with ulcerative colitis in remission who had been treated for a disease relapse, those who underwent laparoscopic appendicectomy combined with standard medical therapy had lower relapse rates at 1 year than those who received standard treatment alone. METHODOLOGY: Researchers conducted a pragmatic randomised controlled superiority trial (2012-2022) at 22…

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NIH discontent, hearing loss, dementia, AI

Theresa Gaffney , 2025-04-18 12:52:00 Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds. Sign up here.Good morning, and happy Friday! Today’s the last day you’ll hear from me for a couple weeks. I’m taking off on a big trip with some of my best friends. But don’t worry,…

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Evaluating hydronidone for the treatment of chronic hepatitis B-associated liver fibrosis

, 2025-04-18 18:57:00 Background and aims Liver fibrosis is a key process in the progression of chronic liver diseases. However, there are currently no drugs specifically designed to treat liver fibrosis. Our Phase 2 trial of hydronidone for the treatment of chronic hepatitis B (CHB)-associated liver fibrosis showed that adding hydronidone to entecavir resulted in…

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New FMF Recommendations Tackle Drug Resistance and Fertility

, 2025-04-18 12:10:00 A multidisciplinary team has released new evidence-based recommendations for the management of familial Mediterranean fever (FMF). Jointly endorsed by the European Alliance of Associations for Rheumatology (EULAR) and the Pediatric Rheumatology European Society, the recommendations are the first update to the 2016 EULAR guidelines. Although rare, FMF is the most common monogenic…

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Low-income patients with diabetes are more likely to experience insurance instability, researchers find

, 2025-04-18 17:35:00 Credit: Pixabay/CC0 Public Domain An Oregon Health & Science University-led study reveals that low-income adults with diabetes are more likely to go in and out of health insurance, and that insurance instability is even worse for those with complex needs. Published in the Journal of American Family Medicine, the study examined electronic…

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Lower temperatures increase the risk of gastroenteritis among Rohingya refugees in Bangladesh

, 2025-04-18 19:08:00 Colder temperatures are linked with increased risk of diarrhea among Rohingya refugees in Bangladesh, emphasizing the need for climate-sensitive health strategies in refugee settings. A new study by scientists at Hokkaido University has found that lower temperatures significantly increase the risk of gastroenteritis among Rohingya refugees living in Bangladesh’s Kutupalong and Nayapara…

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Weight Stigma Remains a Barrier to Patient Care

, 2025-04-18 12:35:00 Obesity has historically been regarded as a moral failing, and people with obesity describe being seen as deficient, lazy, and/or undeserving of respect, lacking willpower and self-discipline, and gluttonous. Negative judgments about obesity persist not only in society at large but also in healthcare settings, despite the American Medical Association’s declaration of…

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On Autism, Kennedy Turns Against Science and Reality

Tarena Lofton , 2025-04-18 22:00:00 During his first news conference as Health and Human Services secretary, Robert F. Kennedy Jr. on April 16 ticked off things he thinks kids with autism will never do, including paying taxes, holding a job, and going on a date. Kennedy’s comments go against science and reality.  This slide presentation…

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NIH halts new grant awards to universities with frozen funds

Anil Oza and Megan Molteni , 2025-04-18 21:24:00 Megan Molteni reports on discoveries from the frontiers of genomic medicine, neuroscience, and reproductive tech. She joined STAT in 2021 after covering health and science at WIRED. You can reach Megan on Signal at mmolteni.13. Embattled universities whose funding from the National Institutes of Health has been…

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Research identifies new cut-off points for overweight and obesity in male athletes

, 2025-04-18 22:10:00 Credit: Unsplash/CC0 Public Domain New research presented at this year’s European Congress on Obesity (ECO 2025, Malaga, Spain, 11–14 May) shows that the internationally recognized body mass index (BMI) cut-off points greatly overestimate overweight and obesity in male athletes. The study, from Italy, also proposes new cut-off points for overweight and obesity…

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Zinc found in glassware may impair embryo development in IVF

, 2025-04-18 19:17:00 1. Overview The research team discovered that glassware used to manipulate and culture fertilized eggs in the fields of assisted reproductive technology (ART), livestock farming, and basic research contains toxic substances that interfere with the development of fertilized eggs (embryos). The team also identified the toxic substance as zinc, and developed a…

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Complexities of Vitamin D in CKD Require Individualization

, 2025-04-18 12:57:00 When it comes to issues of vitamin D in chronic kidney disease (CKD), core certainties include that most patients with CKD have dysregulated 25-hydroxy vitamin D (25[OH]D) and nutritional supplementation can increase those levels. Beyond that, complexities abound, with evidence fraught with confounders regarding who may or may not benefit from supplementation….

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