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RNA-binding proteins on the cell surface

, 2025-04-23 09:00:00 Credit: CC0 Public Domain In 2021, research led by Ryan Flynn, MD, Ph.D., and his mentor, Nobel laureate Carolyn Bertozzi, Ph.D., opened a new chapter in biology, characterizing a new kind of player on the cell surface: glycoRNAs. Extending this discovery recently in Cell, Flynn and colleagues showed that glycoRNAs form highly…

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Mursla Bio receives FDA breakthrough device designation for EvoLiver test

, 2025-04-23 11:42:00 Mursla Bio, a leader in Extracellular Vesicle (EV) science on a mission to significantly improve cancer outcomes for at-risk patients through the power of Dynamic Biopsy technology, today announced that the US Food and Drug Administration (FDA) has granted Breakthrough Device Designation to its lead product, EvoLiver™. The designation recognizes the potential…

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Avoidant/Restrictive Food Intake Disorder Common in IBD

, 2025-04-23 11:09:00 TOPLINE: Nearly 18% of patients with inflammatory bowel disease (IBD), including 16.3% of those with inactive disease, met the criteria for avoidant/restrictive food intake disorder (ARFID). Among patients with inactive IBD, gastrointestinal (GI) symptom–specific anxiety was the only significant predictor of ARFID. METHODOLOGY: Patients with IBD are at increased risk for ARFID…

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IMO motions to call for ban on social media use among under-16s and age verification for online pornography

Michael McHale , 2025-04-23 07:30:00 Proposals to be voted on by members at medical union’s AGM later this week Social media should be banned for all children under 16, while all websites distributing pornography should operate with strict age-verification, members of the Irish Medical Organisation (IMO) will argue later this week. Ahead of its AGM…

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Mediterranean diet lowers breast cancer risk by 13%, postmenopausal women benefit most

, 2025-04-23 03:30:00 A sweeping global review shows that the Mediterranean diet significantly reduces breast cancer risk in postmenopausal women, with Asian populations seeing the strongest effects, highlighting the diet’s potential as a strategic prevention tool. Review: Adherence to Mediterranean Diet and Breast Cancer Risk: A Meta-Analysis of Prospective Observational Studies. Image Credit: Sea Wave / Shutterstock…

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NICE Approves Dual Immunotherapy for Aggressive Bowel Cancer

, 2025-04-23 09:27:00 The National Institute for Health and Care Excellence (NICE) has recommended  nivolumab (Opdivo) plus ipilimumab (Yervoy) for some people in England with advanced colorectal cancer. The treatment is recommended for adults with untreated, unresectable, or metastatic colorectal cancer that shows high microsatellite instability (MSI-H) or mismatch repair deficiency (dMMR). In final draft…

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Mater Private Network hosts leading cardiologists at annual Heart Summit to shape the future of cardiac care

Editorial Staff , 2025-04-23 07:30:00 This year’s programme included expert-led discussions on emerging treatments and innovative technologies Valentín Fuster and Robert Byrne are pictured at the Mater Private Network’s annual Dublin Heart Summit at the Royal College of Surgeons in Ireland (RCSI), which welcomed over 700 cardiologists, GPs and other healthcare professionals to discuss the…

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Specific patient characteristics might contribute to poor recovery after hip replacement surgery

, 2025-04-23 07:10:00 Credit: RDNE Stock project from Pexels Hip replacement surgery, or total hip arthroplasty (THA), can lessen pain and improve function in individuals with hip osteoarthritis, but some patients continue to experience long-term physical deficits—including muscle weakness, decreased functional mobility, and increased fall risk—after the procedure. New research published in the Journal of…

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Raman spectroscopy in bioprocessing: Principles and benefits

, 2025-04-23 07:52:00 In this interview, Dr. Nimesh Khadka, Senior Product Application Specialist at Thermo Fisher Scientific, explores the role of Raman spectroscopy as a process analytical tool (PAT) in bioprocess monitoring, highlighting its molecular specificity, real-time capabilities, and advantages over traditional analytical methods like ultraviolet-visible (UV-Vis) spectroscopy. Could you explain the principles and functioning of Raman…

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AI Shows Promise for Rapid NSTEMI Diagnosis

, 2025-04-23 07:22:00 CHICAGO — A new artificial intelligence (AI) model performed about as well as high-sensitivity troponin for the detection of non–ST-elevated myocardial infarction (NSTEMI) on an ECG, but better than clinicians. “Essentially, the model has rediscovered features on the ECG that we, as clinicians, already recognize as ischemic, but it qualifies these features…

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Roche, NIH funding ban, Galapagos, Wegovy

Elaine Chen , 2025-04-22 13:12:00 Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning, today we look at seemingly conflicting messaging coming out of the NIH, the departure of a key executive at  Galapagos, and more. The need-to-know this morning Roche…

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DNA repair mechanism may hold key to overcoming tumor resistance to radiotherapy

, 2025-04-22 20:26:00 Schematic illustration of ZNF451 regulating DNA damage repair mechanism. Credit: Zhao Guoping A research team has unveiled a crucial mechanism that helps regulate DNA damage repair, with important implications for improving cancer treatment outcomes. The result was published in Cell Death & Differentiation. The team was led by Professor Zhao Guoping at…

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Beckman Coulter Life Sciences transforms purification with the launch of the OptiMATE Gradient Maker

, 2025-04-23 03:41:00 Beckman Coulter Life Sciences, a Danaher company and a global leader in laboratory automation and innovation, announces the launch of the OptiMATE Gradient Maker, a groundbreaking instrument designed to automate the process of density gradient ultracentrifugation (DGUC). The new system accelerates purification processes by up to 75% while improving consistency and reproducibility….

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Hepatitis Testing, Guidance, on Hold as Labs Close

, 2025-04-23 05:59:00 The closure of the Centers for Disease Control and Prevention (CDC)’s Division of Viral Hepatitis in the wake of the administration’s restructuring of the Department of Health and Human Services leaves clinicians and public officials with no resources to process specimens and track outbreaks, according to several experts.  The CDC’s website for…

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What Trump’s AI memos mean for health care

Mario Aguilar , 2025-04-22 16:13:00 You’re reading the web edition of STAT’s Health Tech newsletter, our guide to how technology is transforming the life sciences. Sign up to get it delivered in your inbox every Tuesday and Thursday. In new memos released this month, the Trump administration spelled out its approach to artificial intelligence. At first glance,…

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DASH diet and salt reduction work together to reduce cardiovascular risk

, 2025-04-23 04:07:00 New analysis shows that pairing a low-sodium diet with DASH eating habits reduces cardiovascular risk by over 14%, with the biggest wins for women and Black adults facing high blood pressure. Study: Dietary sodium reduction lowers 10-year atherosclerotic cardiovascular disease risk score: Results from the DASH-sodium trial. Image Credit: New Africa / Shutterstock In…

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What Small Clues Can Teach About Lifesaving Diagnoses

, 2025-04-22 11:19:00 A general practitioner (GP) recently reported that, by chance, he came across a life-threatening diagnosis. He had been chatting with a patient, during which the patient casually mentioned his favorite TV show, “Let’s Dance,” a popular dance competition show in Germany. The patient said that he usually used the commercial breaks to…

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Interferon regulatory factor 8 identified as key driver of liver fat buildup in NAFLD

, 2025-04-23 03:04:00 Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance. Interferon regulatory factor 8 (IRF8) is well known for its roles in immune cell differentiation and tumor pathogenesis; however, its role in regulating glucose homeostasis and lipid metabolism remains unclear. This research, published in the Genes &…

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Underfunding Halts Malnutrition Treatments in Ethiopia

, 2025-04-22 11:52:00 GENEVA (Reuters) -The World Food Programme suspended malnutrition treatment for 650,000 malnourished women and children in Ethiopia this week due to severe funding shortages, the U.N. agency said, with millions more at risk of losing access to aid. WFP gets financing from 15-20 donors including the United States but many of them…

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Post-Pandemic Surge of Group A Strep Infections in Children

, 2025-04-22 11:54:00 TOPLINE: Data over a 32-year period showed that the incidence of invasive group A streptococcal (iGAS) infections in children remained stable before 2011, increased until 2020, declined during the pandemic, and subsequently sharply rose in 2023, with a notable surge contributed by respiratory tract infections. METHODOLOGY:  Researchers evaluated the incidence and clinical…

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Women’s Health Initiative, known for hormone trials, to lose U.S. funds

Elizabeth Cooney , 2025-04-22 21:24:00 Elizabeth Cooney is a cardiovascular disease reporter at STAT, covering heart, stroke, and metabolic conditions. Federal funding for the Women’s Health Initiative, which as one of the largest research projects in women’s health has shaped treatment of menopause, osteoporosis, and nutrition, will stop in September, the program said Tuesday in…

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Federal COVID websites now promote lab leak theory

, 2025-04-22 23:50:00 by I. Edwards The Trump administration has replaced two major federal websites for COVID information with a new page that promotes the theory that the virus came from a lab in China. COVID.gov and COVIDtests.gov, which once helped people order COVID tests and find public health information, now redirect to a new…

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Both Lifestyle and Mortality Poor in ADHD Patients Post MI

, 2025-04-22 12:00:00 TOPLINE: Adults with myocardial infarction (MI) and attention-deficit/hyperactivity disorder (ADHD) were more likely to smoke, use snus, and have histories of bleeding and chronic obstructive pulmonary disorder (COPD) than those without ADHD. Although ADHD was associated with a higher rate of all-cause mortality, these patients were less likely to participate in follow-up…

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