The Immunity journal has published a study exploring possible pharmacological targets in leukocytes. The study revealed CBP/p300 histone acetyltransferase inhibitors increased leukocyte count in bone marrow, blood, and tissues, without adverse side effects. The study used A485 in mice, which accumulated in selected tissues; coincidentally, leukocyte count increased. The research raised queries about the drug’s…
Andisheh Nouraee of Atlanta struggled to sleep, tried wearable and smartwatch tracking and made lifestyle changes that led to better sleep. While technology can track sleep, the key is changing habits to improve sleep quality. Tech enthusiast Bret Brantley found short term behavioral changes but ultimately stopped using sleep tracking. Few people report “very good”…
Recent research suggests that the atypical antipsychotic cariprazine may play a potential role in treating anxiety, which is a commonly overlooked symptom in bipolar I disorder. The drug does not have typical metabolic side effects seen with other medications in its class, making it a promising treatment for anxiety in patients with bipolar disorder. A…
Proper oral hygiene is essential for overall health, and toothpaste plays a crucial role in maintaining dental health. While the Canadian Dental Association recommends using a pea-sized amount for adults, the best toothpaste for you depends on your individual needs and preferences. Some popular options include Crest Pro-Health Advanced Gum Protection, Colgate Total Clean Mint,…
The GSK vaccine Arexvy has been accepted for regulatory review by the European Medicines Agency (EMA) for use in adults aged 50-59 who are at increased risk for respiratory syncytial virus (RSV). This vaccine is being considered for approval to protect this at-risk population from RSV. Additionally, the website uses cookies for analytics, advertising, and…
Altos Neuroscience is bringing precision medicine to psychiatric drug research with its technology, which analyzes biomarkers to match patients with the most effective treatments for neuropsychiatric disorders. The company’s recent IPO has raised $128.6 million, with shares trading on the New York Stock Exchange. Founded in 2019 by Stanford psychiatry professor Amit Etkin, the company’s…
A new survey from the Medical Protection Society (MPS) showed that medical justice is slow in Ireland, which is devastating for patients and doctors. The process costs twice as much as in the UK and takes longer than anywhere else in the world. A report shows that case time actually increased in the years up…
Cytisine, a potential drug therapy for smoking cessation, was found to double the chances of successful smoking cessation compared to placebo in a study published in Addiction. Researchers conducted a systematic review and meta-analysis of 12 randomized controlled trials (RCTs) comparing cytisine with placebo, nicotine replacement therapy (NRT), and varenicline alongside behavioral therapies for smoking…
AION Labs, an AI-enabled drug discovery partnership, has launched a new startup called TenAces. TenAces will use AI to discover molecular glue therapies to enhance targeted protein degradation, potentially treating cancer and neurodegenerative diseases. The company will integrate biology into its machine learning algorithms and work with pharma partners to develop and commercialize solutions. AION…
En 2018, Taliyah Murphy recibió una carta sobre una demanda colectiva en nombre de mujeres transgénero en cárceles de hombres en Colorado, lo que generó esperanza. Las mujeres trans en Colorado han enfrentado acoso sexual y violencia en las cárceles de hombres, y se les ha negado tratamiento médico y vivienda segura. Un acuerdo legal…
At a recent public meeting, attendees testified that the FDA should do more to ensure that pulse oximeters work well in patients with darker skin, better inform clinicians about shortcomings, and recall problematic versions. This follows studies showing that the devices don’t work as well for Black patients, which has led to inaccurate or delayed…
Radosław Stupak, a psychologist and lecturer at the University of the National Education Commission in Krakow, Poland, expresses support for a letter calling for the UK government to reduce the rate of antidepressant prescribing. He hopes that this action will lead to changes in mental health systems globally, moving towards a more socially conscious and…
Cape Verde has been certified as malaria-free by the World Health Organization, making it the third African country to achieve this status. The archipelago has had a long journey to eliminate malaria, which was endemic since the 15th century. The process to get certified malaria-free is stringent, requiring no cases of indigenous transmission for at…
A new off-the-shelf vaccine shows promising early results as a treatment for pancreatic cancer, targeting tumors with mutations in the KRAS gene. The vaccine, tested in a phase 1 trial, is found to be safe and effective in stimulating the immune system to create cancer-fighting cells in patients with pancreatic and colorectal cancer. The vaccine…
The CDC announced that recent COVID-19 vaccinations provide 54% more protection against symptoms compared to unvaccinated individuals. The vaccine is effective against various COVID variants, including the XBB and JN.1 variants. Only 22% of American adults have received the updated vaccine, and public health experts are concerned about the lack of uptake. The vaccine is…
The FDA has approved Edwards Lifesciences’ Evoque tricuspid valve replacement system, the first transcatheter therapy for tricuspid regurgitation in the United States. It is indicated for improving health status in patients with severe tricuspid regurgitation despite optimal medical therapy, offering a less risky option for older patients. The system, which includes a self-expanding frame, intra-annular…
A high-quality diet during infancy has been found to reduce the risk of developing inflammatory bowel disease (IBD) later in life. The researchers recommend incorporating plenty of fish and vegetables in an infant’s diet while minimizing the consumption of sugar-sweetened drinks. Children who had a higher intake of vegetables, fruit, and fish, and a lower…
Lupin, a pharmaceutical company, has launched a Cyanocobalamin Nasal Spray in the United States. This product is designed to provide a convenient and effective way for patients to receive vitamin B12 supplementation. The nasal spray will be available for purchase and is expected to provide a new option for individuals with B12 deficiencies. Lupin’s introduction…
The focus of the content is on the need to bridge the gap in cancer care and research to ensure equitable access to prevention, treatment, and survival for all. The content emphasizes the importance of redirecting funds towards advancing affordable and equitable care and addressing persistent disparities in cancer outcomes. It also highlights the role…
The Irish government has opened a public consultation for new proposals to protect vulnerable adults from abuse while receiving care. The consultation is seeking submissions from the public before the formation of the country’s first national policy on adult safeguarding in the health and social care sector. The proposed policy aims to prevent, respond to,…
The 21-gene recurrence score can predict the benefits of adjuvant chemotherapy for certain breast cancer patients, but its effectiveness varies by race. A study published found that the score is a predictive biomarker for most early-stage estrogen receptor (ER)-positive, HER2-negative breast cancer cases. Asian or Pacific Islander patients did not benefit from the score, and…
Teletherapy company Talkspace and virtual opioid use disorder treatment company Bicycle Health are partnering to expand access to virtual care for patients. Talkspace offers therapy for adults, teens, and couples, as well as psychiatric services and medication management, while Bicycle offers virtual treatment for opioid use disorder. Through the partnership, Talkspace patients will have access…
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Vape maker Juul was revealed to have aggressively pursued partnerships with Black leaders, including discussions of multi-million dollar partnerships with civil rights organizations. internal emails and documents released as part of a legal settlement with the state of North Carolina highlighted this strategy. The company aimed to get Black leaders to publicly support its e-cigarettes,…
The BMA’s General Practitioners Committee for England has warned that many general practices face closure or staff redundancies unless the government improves its contractual offer. The proposed 1.9% increase in funding for general medical services is inadequate and will not prevent practices from reducing services or closing down. The committee expressed concerns that this offer…
Pancreatic cancer is the 3rd leading cause of cancer-related deaths in the US, with a poor survival rate, largely due to metastasis. A study published in Advanced Science by University of California, Davis researchers revealed that the protein Engrailed-1 (EN1) promotes pancreatic cancer progression and metastasis in vitro and in mouse models. EN1 was also…
CAR T cell therapy pioneered at Memorial Sloan Kettering Cancer Center (MSK) is showing promise in treating age-related diseases, such as metabolic decline, and could extend lifespan. The approach, using engineered immune cells to target senescent (nondividing) cells, has potential for diseases like chronic obstructive pulmonary disease (COPD), nonalcoholic steatohepatitis (NASH), osteoarthritis, metabolic syndrome, and…
A new study suggests that taxes on sugary beverages like soda can reduce demand and may improve public health. Research shows that sugary drinks have little nutritional value, and their consumption can increase the risk of diabetes, heart disease, and other chronic diseases. This has led to the introduction of beverage taxes in U.S. and…
The first updated guidelines for specialized epilepsy centers in a decade focus on addressing the overall well-being of patients, including genetic testing and counseling, mental health screening, and special attention to special-needs populations. This shift reflects a move toward comprehensive care beyond seizure management. The guidelines, released by the National Association of Epilepsy Centers, were…
Kimchi, a Korean classic, offers more than just great taste. It has probiotic benefits and can help manage blood sugar, reduce inflammation, and protect heart health. A recent study suggested that daily consumption of kimchi could reduce the risk of obesity in men. The study was based on participants over the age of 40 and…
A phase 3 trial found that oral Sulopenem is as effective as Amoxicillin/Clavulanate for treating uncomplicated urinary tract infections (UTI) in women. The study suggests that Sulopenem could be a viable alternative to the commonly prescribed antibiotic for UTIs. The findings of the trial indicate that Sulopenem could potentially provide a new treatment option for…
The U.S. maternal healthcare system is failing, especially for ethnic-racial minorities and those of lower socioeconomic status. Maternal mortality rates are high, with black women being at a significantly higher risk. Complications often arise after childbirth, and the current system does not effectively address the specific health needs of each patient. However, there is hope…
The inquiry into the use of valproate among pregnant women in Ireland remains without a chair six months after being announced. Precautionary steps are being introduced regarding the prescribing of sodium valproate to men due to potential increased risk of neurodevelopmental disorders in children. The European Medicines Agency advised new precautionary measures, including specialized supervision,…
A combination of sacituzumab govitecan and pembrolizumab showed a “high response rate” in patients with advanced urothelial carcinoma previously treated with platinum-based chemotherapy. In the TROPHY-U-01 trial cohort, 41 patients were treated with the combination, and a 41% objective response rate was observed. The median duration of response was 11.1 months, median progression-free survival was…
CTE awareness month is aimed at promoting dialogue and education about Chronic Traumatic Encephalopathy, a neurodegenerative disease linked to repeated traumatic brain injuries (TBI) commonly seen in athletes and military veterans. Its symptoms include cognitive, mood, and behavioral changes, with no definitive answer regarding its causes. The Concussion Legacy Foundation (CLF) is dedicated to ending…
Visage Imaging has launched Visage Ease VP, an immersive imaging platform for Apple’s augmented reality headset, Apple Vision Pro. The platform allows users to examine diagnostic images in a virtual, spatial setting using eye and hand gestures for navigation. UC San Diego Health will be the first to pilot the technology. Immersive technology is increasingly…
A 9-year-old boy with autism in a North Carolina classroom was physically restrained and secluded multiple times. Federal law does not prohibit this, leading to a lack of accountability and oversight. Thousands of children, particularly those with disabilities and students of color, are subjected to these practices, which can be dangerous and traumatizing. Legislation to…
Lurie Children’s Hospital in Chicago has faced a cybersecurity issue, leading to the hospital taking its network offline. They are working with experts and law enforcement while still remaining open. The Department of Health and Human Services has warned of increased cyber threats against hospitals and outlined voluntary cybersecurity goals. Data breaches in the health…
Scotland’s inquiry on the handling of the pandemic reveals that half of the country’s deaths in the first wave occurred in care homes. Former health secretary Jeane Freeman stated regret over these preventable deaths and emphasized that testing capacity was a primary issue. Former first minister Nicola Sturgeon admitted to regrets and said she should…
A new meta-analysis from the Hackensack Meridian School of Medicine and Hackensack Meridian Health Research Institute shows a positive trending shift towards equity and inclusivity in clinical trials and medical research. The analysis of clinical trials from 2017 to 2022 including New Jersey patients reveals more diverse representation and better reporting of race and ethnicity…
Millions of hunters in North America hunt deer each fall and consume the venison. However, experts are concerned about chronic wasting disease (CWD), a rapidly spreading, contagious, and always fatal neurological disease in deer. The prions causing CWD may be evolving to infect humans, and experts are worried about a potential spillover into humans and…
Joan Kathryn, 79, was diagnosed with age-related macular degeneration (AMD) in 2008. She has developed wet AMD in her left eye and geographic atrophy (GA) in both eyes. The condition has made it difficult for her to recognize faraway faces, read fine print, and find small objects. Despite the challenges, she has adapted by using…
Organ donations after medical assistance in dying (MAiD) accounted for 14% of total deceased donations in Quebec in 2022, according to new research. The study found that since 2018, there has been an increase in referrals and completed cases for organ donations after MAiD. During the study period, Transplant Québec received 245 referrals for donation…
Dietary fiber from fruits, vegetables, whole grains, and legumes offers essential health benefits, such as aiding digestion, controlling blood sugar, lowering cholesterol, and contributing to weight management. If it’s difficult to get enough fiber from regular meals, fiber supplements can help fill the gap. There are various options available, including gummies and capsules, for both…
The health budget for 2024 has been announced, with a focus on key healthcare initiatives. The initiatives aim to improve the overall healthcare system and address current challenges. The budget will allocate funds to support the implementation of these initiatives, including investments in technology, infrastructure, and healthcare services. The goal is to enhance the quality…
Cigna is selling its Medicare Advantage, supplemental benefits, Medicare Part D, and CareAllies businesses to Health Care Service Corporation (HCSC) for $3.7 billion. This move is expected to close in early 2025 and will reduce the regulatory challenges Cigna might face if it were to combine with Humana. HCSC is a licensee of the Blue…
The HSE has agreed to introduce interim discipline managers in Children’s Disability Network Teams (CDNTs) after concerns were raised by various professional organizations about clinical governance and risk management in children’s disability services. The new roadmap for service improvement aims to address an imbalance in service provision and improve access to services for children and…
Prenatal infections could be a risk factor for psychiatric symptoms in children, according to recent research. The study, based on the Generation R Study, found that exposure to prenatal infection was linked to higher total, internalizing, and externalizing problems across development. The research, which analyzed data from over 3,500 mother-child pairs, used linear mixed-effects models…
Scientists have discovered a mutual dependence between human microbiota and our health, particularly in relation to the onset of Crohn’s disease. New research from the University of Toronto has shown that genetics, environmental factors, and gut flora can trigger Crohn’s disease. DNA sequencing has allowed for the identification of bacteria in the gut, and researchers…
Kakao Healthcare has launched the PASTA app for diabetes management, which provides real-time blood sugar data and nutrition information. Microsoft has partnered with South Korean company Seegene to integrate its AI services into the SG OneSystem for PCR-based diagnostic solutions. Aevice Health and Jiva.ai are working on an AI-driven system to predict asthma exacerbations using…