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Sotagliflozin Lowers A1c, Weight Even in Kidney Impairment

, 2025-05-17 14:20:00 ORLANDO, Florida — Sotagliflozin (Inpefa) reduces A1c and body weight in people with type 2 diabetes, although the degree of improvement was attenuated in those with moderate-to-severe chronic kidney disease (CKD).  “These findings highlight the importance of considering the effect of kidney function to help inform and tailor treatment decision-making for patients…

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AI-enabled ECG algorithm performs well in the early detection of heart failure in Kenya

, 2025-05-17 12:30:00 Credit: Unsplash/CC0 Public Domain An artificial intelligence-enabled electrocardiogram-based algorithm performed well in the early detection of heart failure among health-care-seeking individuals in Kenya, according to late-breaking research presented Heart Failure 2025. Heart failure is highly prevalent in Sub-Saharan Africa, where patients are often younger and face worse outcomes than in high-income countries….

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7 T MRI Matches 3 T for Diagnosing Wrist Ligament Injuries

, 2025-05-16 12:00:00 TOPLINE: MRI at 7 tesla (T) and 3 T field strengths showed similar accuracy in detecting triangular fibrocartilage complex (TFCC) and scapholunate ligament (SLL) injuries, according to a new study. Although some injuries were missed, MRI identified additional pathologies not seen on arthroscopy, supporting its complementary role in diagnosis. METHODOLOGY: This prospective…

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Researchers develop biocompatible patch for soft organ injuries

, 2025-05-17 12:30:00 Immunofluorescent staining for macrophages (CD68, green) and nuclei (DAPI, blue) on the hydrogel-tissue interface seven days after artery incisions in rats. Credit: Dr. Mahsa Ghovvati University of California, Los Angeles and University of California, San Diego researchers developed an injectable sealant for rapid hemostasis and tissue adhesion in soft, elastic organs. Formulated…

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Cardiac ‘digital twins’ provide clues to more personalized heart treatments

, 2025-05-17 01:25:00 For the first time, researchers from King’s College London, Imperial College London and The Alan Turing Institute, have created over 3,800 anatomically accurate digital hearts to investigate how age, sex and lifestyle factors influence heart disease and electrical function. Creating cardiac ‘digital twins’ at this scale has helped scientists discover that age…

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Age Matters in Gallbladder Surgery Success

, 2025-05-16 12:00:00 TOPLINE: Undergoing cholecystectomy at a younger age (< 40 years) was associated with higher long-term mortality, potentially influenced by higher alcohol use and smoking. METHODOLOGY: This nationwide Swedish cohort study examined the long-term mortality outcomes after cholecystectomy in 159,946 adults (62.2% men) aged 20-79 years who underwent the procedure between 1969 and…

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Reed Jobs warns Trump’s science cuts will set back cancer research

Mario Aguilar , 2025-05-16 08:30:00 Mario Aguilar covers technology in health care, including artificial intelligence, virtual reality, wearable devices, telehealth, and digital therapeutics. His stories explore how tech is changing the practice of health care and the business and policy challenges to realizing tech’s promise. He’s also the co-author of the free, twice weekly STAT…

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US approves first blood test for Alzheimer’s

, 2025-05-17 11:20:00 Credit: Karolina Grabowska from Pexels The United States on Friday approved the first blood test for Alzheimer’s, a move that could help patients begin treatment earlier with newly approved drugs that slow the progression of the devastating neurological disease. The test, developed by Fujirebio Diagnostics, measures the ratio of two proteins in…

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Postpartum Mental Illness Common in Year 2

, 2025-05-16 12:00:00 TOPLINE: A large UK cohort study found that the prevalence of women experiencing moderate to severe mental illness in the second postpartum year increased from 3.1% to 7.4% between 1995 and 2018, supporting extended perinatal mental health (PMH) services. METHODOLOGY: This retrospective cohort study analysed data of 2,132,754 pregnancies from 1,361,497 women…

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No cardiac safety concerns reported with a pharmaceutically manufactured cannabidiol formulation

, 2025-05-17 08:50:00 Credit: Unsplash/CC0 Public Domain A pharmaceutically produced cannabidiol formulation had a good overall safety profile, including cardiac safety, according to research presented at Heart Failure 2025. Currently, there are limited treatment options for inflammatory conditions of the heart, such as myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the membrane…

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Study reveals how acetaminophen may actually relieve pain

, 2025-05-17 01:53:00 A new study from Indiana University scientists may aid the pharmaceutical industry in better understanding a popular over-the-counter pain reliever: Tylenol. Michaela Dvorakova, a postdoctoral researcher at IU’s Gill Institute for Neuroscience and the College of Arts and Sciences’ Department of Psychological and Brain Sciences, and Gill Institute research scientist Alex Straiker…

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Why Aren’t More PCPs Ordering Allergen Tests?

, 2025-05-16 12:00:00 Few primary care providers (PCPs) are testing patients with asthma who have suspected allergen triggers, which may delay treatment that could improve outcomes, new data suggested. Mridula Sree Naagendran, MBBS, internal medicine resident at UConn Health in Farmington, Connecticut, presented the information in a poster at the Society of General Internal Medicine…

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Journalists Unpack Drug Prices, Threats to Medicaid, and the Fluoridation of Water

, 2025-05-17 09:00:00 Céline Gounder, KFF Health News’ editor-at-large for public health, discussed the FDA’s phasing out of fluoride drops and tablets for children on CBS’ “CBS Mornings” on May 15. Click here to watch Gounder on “CBS Mornings.” KFF Health News Southern correspondent Sam Whitehead discussed what Medicaid cuts could mean for Georgia on The…

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New Weight-Loss Options Improve Cardiac Health

, 2025-05-16 12:26:00 Weight gain can lead to high blood pressure, type 2 diabetes, and dyslipidemia, a metabolic disorder of abnormal lipids. As the body gets bigger, cardiac changes occur and the left ventricle — the heart’s main pumping chamber — enlarges too. The ventricle thickens and it can be more difficult to pump blood…

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Amgen loses $400 million antitrust battle to Regeneron

Meghana Keshavan , 2025-05-16 13:36:00 Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Morning! Today we start with some breaking newss: Novo Nordisk’s CEO is stepping down. We also discuss a new, tailored CRISPR treatment for an infant with a deadly disease, how…

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Toxic metals found in all rice samples in new report

, 2025-05-16 17:43:00 by I. Edwards A new report says rice sold in U.S. stores contains toxic heavy metals, including arsenic, cadmium, lead and mercury. The report—released by Healthy Babies, Bright Futures—found arsenic in 100% of rice samples tested from stores in 20 metro areas, including New York City, Los Angeles and Miami, CBS News…

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Ochsner’s kidney transplant program earns national ELITE Status

, 2025-05-17 02:32:00 Ochsner Health proudly shares its kidney transplant program, part of the Ochsner Transplant Institute, has been awarded ELITE Status within the credentialed Programs of Excellence transplant network by INTERLINK COE Networks & Programs. ELITE Status is awarded to only a select few programs nationwide certifying delivery of superior transplant care.  To earn…

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Fracture Risk Lower With Semaglutide vs Sleeve

, 2025-05-16 12:27:00 Orlando, Fla. — Fracture risk in people treated for obesity appears significantly lower with semaglutide (Wegovy) vs sleeve gastrectomy, new data suggest. Previous animal studies have suggested a dose-dependent effect of glucagon like peptide 1 (GLP-1) receptor agonists on trabecular bone, including increased osteoblast activity, reduced apoptosis, and suppressed osteoclast activity. However,…

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Federal Budget Bill Includes Medicare Pay Hike for MDs

, 2025-05-16 12:28:00 The massive budget bill now being debated in Congress includes a proposal for raising Medicare pay for clinicians starting in 2026. That could be good news for physicians who in 2025 saw a nearly 3% effective pay cut in Medicare reimbursement. However, clinicians and advocates remain concerned about potentially large cuts to…

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Genomic study of non-Hispanic Black veterans with prostate cancer yields key insights for precision medicine

, 2025-05-17 03:43:00 In the largest clinical genomic profiling study of non-Hispanic Black men with metastatic prostate cancer to date, researchers from Moffitt Cancer Center, University of Pennsylvania, University of California Los Angeles and the Veterans Affairs (VA) National Precision Oncology Program found key differences in tumor biology between non-Hispanic Black and non-Hispanic white veterans, but similar survival outcomes when…

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Maternal Disability Linked to Higher Infant ED Use

, 2025-05-16 12:29:00 TOPLINE: Infants born to mothers with disabilities had higher rates of emergency department (ED) visits in their first year of life than those born to mothers without disabilities. METHODOLOGY: Researchers conducted a population-based study of 1,596,932 live-born infants from April 1, 2008, to March 31, 2021, in Canada. A total of 139,698…

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New ‘Real World’ Data on Lecanemab Side Effects

, 2025-05-16 12:54:00 Patients with early Alzheimer’s disease (AD) who initiated lecanemab treatment at a specialty memory clinic showed an expected and manageable side-effect profile, new research showed. “The findings are very reassuring,” Barbara Joy Snider, MD, PhD, professor of neurology, and director of the Memory Diagnostic Center and Knight ADRC Clinical Trials Unit, Washington…

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Navigating Market Volatility in 2025

Ronan McGrath , 2025-05-16 07:30:00 In today’s financial landscape, global markets are experiencing notable volatility, writes Ronan McGrath These are challenging, emotional times for investors, particularly those nearing or in retirement. While several factors contribute to the current turbulence, the primary driver is President Trump’s erratic tariff policy, which has injected fresh instability into the…

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Does the CDC have an acting director?

Helen Branswell , 2025-05-16 21:55:00 Earlier this week, Lisa Blunt Rochester asked a seemingly simple question of Robert F. Kennedy Jr. during his testimony to the Senate’s Health, Education, Labor, and Pensions Committee: “Who is the acting CDC director?”  Kennedy, the secretary of Health and Human Services, offered the name “Matt Buzzelli,” who he described…

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