A study published in Nature Medicine found that an excess of Vitamin B3, or Niacin, may increase the risk of cardiovascular disease. Researchers discovered that a metabolite of excess niacin, N1-methyl-4-pyridone-3-carboxamide (4PY), is linked to an increased risk of cardiovascular events. The study identified a previously unknown pathway that causes adverse cardiovascular events due to…

Academic and doctor representative groups are concerned about sudden changes to the allocation of academic foundation jobs for 2025. The UK Foundation Programme Office announced that recruitment into specialized foundation programs in England, Scotland, and Northern Ireland will be incorporated into the main allocation process. This system, already in place in Wales, allows doctors to…

Inuit people living in northern Quebec’s Nunavik region are dying earlier from lung cancer than Montreal residents being treated at the same cancer center in Montreal, according to a new study published in the Canadian Medical Association Journal. All Nunavik residents are treated at McGill University Health Center (MUHC) in Montreal due to limited resources…

A study found that patients who achieved remission from Cushing’s disease after pituitary surgery were more likely to develop new-onset autoimmune disease within 3 years. This was compared to those with surgically treated nonfunctioning pituitary adenomas. Researchers found a cumulative incidence of 10.4 percent of new autoimmune diseases in the Cushing’s disease group. They suggest…

“Detox” products that claim to clean your lungs have no scientific evidence behind them, since lungs are capable of cleaning and repairing themselves in some cases. To prevent further lung damage, avoid secondhand smoke, vaping, pollutants, and viruses through vaccinations and air quality monitoring. A diet rich in antioxidants, cardiovascular exercise, and regular handwashing are…

Transcatheter arterial chemoembolization (TACE), typically used for treating liver metastases from colorectal cancer, was applied to locally advanced rectal tumors in a study. Known as transcatheter rectal arterial chemoembolization (TRACE), the treatment was administered to 111 patients with stage II or III rectal tumors. The results showed a pathological complete response in 20.7% of patients…

Xolair, a medication originally developed to treat asthma, has now been approved to prevent severe allergic reactions to food. This medication is designed to target and block the body’s immune response to specific food allergens, reducing the risk of anaphylaxis. This approval provides hope for individuals with serious food allergies, such as peanuts and tree…

A study found that Asian breast cancer patients undergoing taxane-based chemotherapy may experience skin changes and hair loss. The study emphasized the need for personalized treatment and support for these patients to manage these side effects. The findings suggest that Asian patients with breast cancer may have different experiences with chemotherapy compared to other populations,…

Brain-Computer Interfaces (BCIs) are a transformative force in healthcare, allowing for seamless integration between the human brain and external devices. They have evolved from providing basic communication for individuals with disabilities to more sophisticated applications, including assistive technology, patient monitoring, and treatment of neurological disorders. The future of BCIs in healthcare is promising, with potential…

The HSE in Ireland will offer permanent employment contracts to all nursing, midwifery, and health and social care (HSCP) graduates. This includes over 1,000 final year HSCP students and 1,600 nurses and midwives. The initiative aims to address shortages of frontline staff and is part of the HSE’s 2024 National Service Plan, which includes a…

mPulse, a conversational AI and digital engagement platform, reported a 94% growth in Q4 2023 and a 106% year-over-year growth. The company attributes this growth to acquisitions of HealthTrio and Decision Point Healthcare Solutions, as well as organic growth. mPulse partners with 19 of the top 20 health plans in the U.S. and over 300…

More than half a million Anthem Blue Cross enrollees were at risk of losing access to the University of California’s health care due to a contract dispute. UC Health accused Anthem of not negotiating in good faith, while Anthem claimed UC Health was demanding too much. The conflict was part of a trend where patients…

Alain Cribier, a pioneer of interventional cardiology, passed away at the age of 79. He performed the first tanscatheter aortic valve replacement that ushered in a new era of treatment for people with severe aortic stenosis. Throughout his career, he made numerous contributions to the field of cardiology and mentored up-and-coming interventional cardiologists. His passing…

The National Institutes of Health has launched a precision medicine initiative called “All of Us” to gather data from 1 million participants. The data aims to address the lack of diversity in genomic datasets by including individuals from different ethnic backgrounds. This initiative has gathered new genetic information from millions of DNA variants and is…

The head of UK’s infection control specialists wants more clarity from the drug regulator on recent advice to only use fluoroquinolone antibiotics when absolutely necessary. Doctors are confused and fearful of legal repercussions if patients experience side effects. The Medicines and Healthcare Products Regulatory Agency (MHRA) released an update in January stating that fluoroquinolones should…

A team of international scientists developed an innovative treatment for chronic wounds involving ionized gas called plasma. The scientists increased plasma activation of hydrogel dressings using a unique mix of various chemical oxidants that decontaminate and assist in healing chronic wounds. These plasma-activated hydrogels are capable of killing common bacteria and may help trigger the…

A study published in JAMA Network Open evaluated cognitive symptoms in individuals with post-COVID-19 condition compared to those who had recovered from SARS-CoV-2 infections. The study found a high prevalence of cognitive symptoms in those with long COVID, which was associated with functional impairments and lower likelihood of full-time employment. There was also a greater…

Just after surgery for diverticular disease, Greg Saggio ignored his doctor’s advice and rushed back to work, only to experience pain, discomfort, and diarrhea as a result. It’s important to follow the doctor’s dos and don’ts, move around as soon as you’re cleared, and not skimp on pain medication. Eating and drinking regularly is essential…

Loneliness is a silent epidemic that affects people of all ages, not just older adults. The toll on health is severe, with links to cardiovascular risks, mental health struggles, and even increased risk of developing dementia. The World Health Organization has launched a Commission on Social Connection to address this issue. Loneliness has been linked…

Researchers have found that starting your day with a high-protein breakfast can help improve concentration and feelings of fullness throughout the day. Protein in the diet is important for growth and repair, and a high-protein breakfast may help reduce overall daily calorie intake. A study found that a dairy-based, high-protein, low-carbohydrate breakfast can increase satiety…

The Parliamentary Committee suggested several measures to make medical education more affordable, including increasing government investment in medical colleges and institutions, providing scholarships and financial aid to aspiring medical students, and regulating tuition fees to prevent excessive and arbitrary increases. The Committee also recommended the establishment of a centralized entrance examination for medical courses to…

Astellas Pharma has entered into a collaboration with Kelonia Therapeutics to create in vivo CAR T-therapies through genetic cargo delivery. This technology enables the modification of immune cells, targeting cancer cells and improving the ability to destroy tumors. The collaboration will develop up to two in vivo CAR T-therapy programs, with undisclosed targets. Kelonia will…

The National Self-Harm Registry Ireland’s annual report found that in 2021, women had a 45% higher rate of self-harm hospital presentations than men, the largest gender gap in 20 years. The rates remained consistent through the pandemic, with the highest rates among young people. The peak rate for women was in the 15-19 years age…

A recent study in South Korea found that older adults, especially those who are frail, have different purposes and satisfaction levels in using healthcare apps and wearable health devices. Researchers surveyed 505 respondents, 30% of whom were considered frail, and found that healthy seniors were more likely to use healthcare apps for self-care and managing…

Millions of Medi-Cal beneficiaries in California can now save money and assets without losing their coverage due to an eligibility change. This change has opened the door for new enrollees and eliminates the requirement to prove the value of financial accounts and personal property. The income threshold must still be met, but now almost two…

At a recent symposium, William Rigby, MD, discussed the unprecedented efficacy of chimeric antigen receptor T-cell therapy in lupus patients, reporting almost complete disappearance of symptoms. However, long-term impacts remain to be seen, as B-cell responses eventually returned. Rigby presented findings from a study that showed that CAR-T cell therapy was more effective than other…

After 40 years in development, the first TIL therapy received accelerated approval from the FDA for advanced melanoma. The therapy, called Amtagvi or lifileucel, is the first cell therapy approved for a solid tumor. During a phase 2 clinical trial, 31% of patients responded to the therapy, with 42% of those patients continuing to respond…

serve populations with fewer patients from deprived areas, while those with smaller private income tend to serve more deprived populations. This suggests that wealthier areas may have better access to private healthcare, while poorer areas rely more on NHS services. The study also highlights the potential impact of private patient income on NHS funding and…

Smoking causes lasting effects on the immune system even after quitting, according to a new study published in the journal Nature. Researchers analyzed blood samples from 1,000 healthy people in France and found that smoking alters adaptive and innate immunity. Although adaptive immunity remains affected for years, even decades, innate immunity rebounds immediately after people…

A recent study published in the CDC journal investigated the prevalence of long COVID among adults in the United States. Researchers found that 6.4% of adults experienced long COVID, with rates varying from 1.9% in the Virgin Islands to 10.6% in West Virginia. The study utilized data from the 2022 Behavioral Risk Factor Surveillance System…

Keeping a healthy weight as you age is important, though it can be more difficult. The basic rules for weight loss still apply: burn more calories than you consume, eat nutritious foods, and avoid empty calories. If you’re over 60 and want to lose weight, there are extra steps to take. Strength training helps maintain…

A study presented at the American Academy of Orthopaedic Surgeons’ 2024 annual meeting suggests that watchful waiting for shoulder adhesive capsulitis (frozen shoulder) is medically appropriate and can lead to substantial cost savings compared to physical therapy. Researchers found that patients who received no active treatment for the condition showed similar reductions in symptoms over…

Recent research suggests that probiotics, typically known for their benefits to gut health, may also play a key role in promoting digestive and cognitive well-being. The connection between the gut and brain relies on the communication between the enteric and central nervous systems, with the vagus nerve as the primary communicator. The gut, referred to…

Exoscope technology is a highly advanced tool that has shown excellent outcomes in spinal neurosurgery cases. It offers precise visualization and maneuverability, leading to better surgical results. The technology uses cookies for analytics, advertising, and site improvement. By continuing to use the site, users agree to the use of cookies. To learn more about the…

Biopharma companies often use outdated data tools like Microsoft Excel, leading to fragmented and manual data processing. With the explosion of data in the industry, companies are looking to adopt more sophisticated digital technologies, such as the “digital twin,” to streamline data collection and analysis. A “digital data backbone” is being seen as essential to…

A new network in Ireland, called EQUIPS, has been established to advance and improve the understanding of quality and patient safety research. The HSE and Health Research Board have jointly funded the network with €1.25 million over five years. Led by Prof Samuel Cromie and Dr Orla Healy, the network will bring together stakeholders, researchers,…

Children receiving chemotherapy for cancer may experience negative eating behaviors, such as changes in taste, emotional overeating or undereating, food selectivity, and slow eating. The study, conducted on children aged 8 to 18 being treated for cancer, found that most of them had normal body mass index (BMI) scores, but some were at risk for…

Celine Gounder from KFF Health News spoke on “CBS Mornings” about the CDC considering changes to isolation guidelines for COVID-19 and how to protect others while still testing positive. KFF Health News provides in-depth health journalism and is part of KFF, an independent source of health policy research, polling, and journalism. The story can be…

Dr. Jordan M. Graff, MD, FACS, presented a post hoc analysis of the YOSEMITE and RHINE clinical trials at Retina 2024, evaluating biomarkers for vascular stability. The trials compared faricimab vs. aflibercept in patients with diabetic macular edema, and found that faricimab showed a greater reduction in hyperreflective foci and vascular leakage. This suggests that…

Prominent immunologist and oncologist Padmanee Sharma is facing a lawsuit that accuses her of threatening to harm a junior faculty member’s career, making defamatory comments about them, and trying to take credit for work she did not do. Sharma defended herself, saying her contributions were ignored, and a third-party assessment concluded she should be given…

William “Ian” Jones was born in Tregaron, Cardiganshire, and studied medicine in Cardiff. After completing two years of national service in Singapore, he began a career in ear, nose, and throat (ENT) medicine under the guidance of Don Harrison at the Royal National Throat, Nose, and Ear Hospital. He earned his fellowship in 1964 and…

A study conducted by a team of researchers including Rebecca Fischer, Ph.D., assistant professor in the Department of Epidemiology and Biostatistics at Texas A&M University School of Public Health, analyzed the efficacy of the Moderna mRNA-1273 vaccine in preventing infections and symptomatic COVID-19 in young adults. The study followed 1,149 young adults aged 18-29 over…

Researchers led by Northwestern University and the University of Wisconsin-Madison have developed a new approach to treat neurodegenerative diseases. The approach targets antioxidant response and is an important part of cellular protection against oxidative stress. The discovery was published in Advanced Materials and aims to disrupt the protein interaction responsible for oxidative stress in diseases…

Bloating, gassiness, and abdominal discomfort can occur due to overeating, eating rich and fatty foods, and eating too fast. Gas in the abdomen can also cause bloating. Swallowing air and consuming certain foods can contribute to bloating as well. Foods like beans, lentils, fruits, vegetables, sweeteners, dairy products, and whole grains can cause gassiness and…

The FDA has approved omalizumab (Xolair, Genentech) to reduce allergic reactions to foods in adults and most children. The drug is meant to be taken regularly to reduce the risk for reactions, including anaphylaxis, in case of accidental exposure to allergens. Omalizumab is not approved for emergency treatment. It is the first drug approved to…

Probiotics are essential for optimal health, especially for women. Wholesome Wellness Women’s Raw Probiotics are high-potency supplements designed to support digestive and immune health. For men, Garden of Life RAW Probiotics Men provides comprehensive and targeted benefits. PurelyPure Probiotics is ideal for those with allergies. MegaFood MegaFlora is vegan-friendly, and Thorne FloraMend Prime Probiotic is…

The city of Palwal is set to receive its first government medical college. This development will provide better access to medical education and healthcare services for the residents of Palwal. The establishment of the medical college signifies a significant step towards improving the healthcare infrastructure in the region. With the introduction of this institution, the…

The integration of Generative AI with CPQ systems in healthcare can revolutionize the industry. This integration allows for personalized treatment plans, streamlined supply chain management, and accelerated drug discovery. Generative AI can analyze extensive data sets to tailor treatment options to individual patient needs. It can also predict demand, optimize stock levels, and detect fraud…

A study led by an Irish researcher at University College Cork found that a new drug combination shows promising results in treating advanced HER2-negative breast cancer. The combination of a histone deacetylase (HDAC) inhibitor and two types of immunotherapy led to one-in-four women having their tumors destroyed or significantly reduced. The study, led by Prof…

A study compared the effectiveness of TNF inhibitors, JAK inhibitors, and IL-17 inhibitors in improving the SPARCC score of the sacroiliac joint in patients with axial spondyloarthritis. The analysis included 18 randomized controlled trials, which showed that all three types of inhibitors were equally effective in reducing the SIJ SPARCC score at 3 months. TNF…