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Biogen, Eisai, Aardvark Therapeutics, etc.

Stay informed on the latest in biotech by signing up for the newsletter. Recent developments include scientists discovering a way to target aggressive pediatric tumor cells using tumor-suppressor genes. A U.K. health agency’s decision on an ALS drug by Biogen raises concerns about access to genetic medicines. Generic versions of diabetes drugs could be more…

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How to Manage MS with Exercise and Eating Well

When Laura Wells was diagnosed with MS at 39, her focus on health was sporadic due to raising young kids. After kids grew older, she struggled with worsening MS symptoms but found yoga helped her stay active. Wells emphasizes the importance of small daily exercise, healthy eating, and balance in managing MS symptoms. She also…

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Full-Dose Beta-Lactam Allergy Challenges in ED

A study found that full-dose challenges of beta-lactam antibiotics in emergency department patients with moderate, severe, or unknown allergies can safely reduce unnecessary antibiotic regimens, save costs, and preserve future antibiotic effectiveness. The study analyzed data from 184 patients with beta-lactam allergies treated in the ED, with 90% reporting penicillin allergies. Allergic reactions were noted…

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AI Disruption is Coming. Are Healthcare Professionals Ready?

The artificial intelligence (AI) market is expected to exceed $400 billion by 2027, driving demand for professionals with expertise in machine learning, especially in the healthcare sector. To stay competitive, healthcare corporations and academia must empower ambidextrous professionals with skills in both AI and health science. Large healthcare companies are integrating AI to improve efficiencies,…

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How Primary Care Is Being Disrupted: A Video Primer

The way patients interact with their doctors is changing, potentially affecting access to and quality of care in the future. More than 100 million Americans lack regular access to primary care, despite a rise in demand partially due to Affordable Care Act enrollment. The traditional model of seeing the same doctor for decades is shifting…

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How to make social media a positive force for teen mental health

Public concern has increased regarding the impact of social media on teen mental health following the U.S. surgeon general’s advisory. Calls to ban teens from social media apps have emerged, but researchers suggest that social media could actually offer support for adolescent mental health. Many teens, especially those with minoritized identities, rely on digital spaces…

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Why Trump’s surgeon general is fighting big medical bills

Former US surgeon general Jerome Adams received a $5,000 medical bill for dehydration treatment in Arizona. He is calling for healthcare reforms to address the high costs and lack of transparency. Adams, a Black physician, highlights the struggles of many Americans with medical debt. He suggests market-based reforms, including more transparency, an arbitration process for…

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Irritable bowel syndrome not linked to higher Parkinson’s risk, study finds

A recent study published in npj Parkinson’s Disease explores the relationship between Parkinson’s disease (PD) and irritable bowel syndrome (IBS). PD is a common neurodegenerative disease with symptoms like tremors and stiffness, while IBS is a gastrointestinal disease with abdominal discomfort and bowel alterations. The study utilized data from the UK Biobank and found that…

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5 Things You May Not Know

More than half of American women aged 18-49 masturbate regularly, both single and in relationships. Masturbation is a stigma-free way to boost mood, release stress, and increase sexual comfort and confidence. It can help women explore their desires, improve sexual experiences, and experiment with different sensations to reach orgasm. For women experiencing changes during menopause,…

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How Does Diet Affect Gastroesophageal Reflux Disease?

Diet plays a crucial role in managing gastroesophageal reflux disease (GERD), with key recommendations including elevating the head of the bed, allowing a gap between meals and bedtime, and weight loss. Caloric intake and lipid content in meals impact esophagogastric physiology, with high-calorie, high-fat, or high-carbohydrate meals promoting reflux symptoms. Recent studies highlight the benefits…

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5 persons sentenced to life imprisonment

In the Bhubaneshwar Doctor Couple murder case, five persons have been sentenced to life imprisonment. The couple was brutally murdered, and the perpetrators have been held accountable for their actions. This case has brought justice to the victims and their families. The sentencing of the perpetrators marks the culmination of a long and difficult legal…

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Insurer “Delay and Deny” Practices Continue to Threaten Patients’ Timely Access to Gastrointestinal Care – It’s Time for Reform

Patients with gastrointestinal (GI) health issues like rectal bleeding and inflammatory bowel disease need timely colonoscopies and endoscopies for individualized treatment plans. However, insurance practices like prior authorization often delay or deny necessary care, leading to adverse health impacts, hospitalizations, and patients abandoning treatment. Insurers prioritize cost over patient health by requiring prior authorization for…

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Recognizing HIE: A Call for Advocacy

Hypoxic Ischemic Encephalopathy (HIE) is a leading cause of infant mortality and disability globally, affecting 2-3 per 1,000 live births in high-income countries and up to 30 per 1,000 live births in low and middle-income countries. Early recognition of HIE is crucial for improved outcomes. Advocacy for better understanding and support for infants with HIE…

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Lenmeldy, GLP-1s and Oprah, autoimmune disease

Adam’s Biotech Scorecard is a new newsletter offering insights on the biotech industry by senior reporter Adam Feuerstein. In the latest issue, topics include FDA approval for Akebia Therapeutics’ Vafseo, Gilead Sciences licensing an experimental cancer drug, and the world’s costliest drug, Lenmeldy, priced at $4.25 million. The newsletter also discusses immune senescence and potential…

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Study suggests high blood pressure could begin in childhood

Children and teenagers who are overweight or obese are more likely to develop high blood pressure as adults, according to new research presented at the European Congress on Obesity. The study found that even small increases in BMI during childhood and puberty can lead to higher blood pressure in midlife, increasing the risk of cardiovascular…

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DNA repair process key to memory formation, study finds

Researchers in a study published in Nature found that DNA damage in the hippocampus neurons during learning triggers a cascade of molecular events leading to memory formation. The study focused on the role of toll-like receptor 9 (TLR9) in repairing the double-stranded DNA damage in neuronal clusters. Transcriptional profiles were analyzed in murine models subjected…

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5 Mistakes Parents Make With Teens

Parenting a teenager or tween can be challenging as they test limits and push boundaries. It is important to focus on your child’s interests and hobbies, even if you don’t fully understand them. Rather than relying solely on parenting books, trust your instincts and communicate your family’s values clearly. Stay involved and watch for signs…

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COPD patients with severe disease and recent exacerbations more likely to continue chest wall oscillation therapy: Study

A recent study found that patients with severe chronic obstructive pulmonary disease (COPD) who have experienced recent exacerbations are more likely to continue receiving chest wall oscillation therapy. The therapy helps to improve lung function and reduce symptoms in COPD patients. The study suggests that patients with more severe disease and recent exacerbations may benefit…

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Study finds association between TB infection and increased risk of various cancers

A study presented at the European Congress of Clinical Microbiology and Infectious Diseases found an association between tuberculosis (TB) infection and an increased risk of various cancers. The study, conducted in South Korea, revealed that TB patients had a significantly higher incidence of cancer compared to the general population, including lung, blood, gynecological, colorectal, thyroid,…

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Enhancing patient empowerment in plastic surgery through social media

Social media use among patients considering or undergoing plastic and reconstructive surgery (PRS) procedures can enhance patient empowerment, leading to increased autonomy and better decision-making. A study found that patients seeking information online had higher empowerment scores, especially on social media platforms like Facebook and RealSelf. Plastic surgeons are encouraged to engage and contribute to…

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How and Why Teens Manipulate Their Parents

Teenagers are experts at manipulating their parents to get what they want, avoid trouble, or feel powerful. Experts suggest countering this manipulation with tactics such as setting boundaries, enforcing consequences, and being consistent. Parents should establish rules and stick to them, even in the face of emotional blackmail or sulking. By setting limits on activities,…

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Bristol Myers’ Bowel Disease Drug Fails in Late-stage Study

Bristol Myers Squibb’s experimental drug for Crohn’s disease, ozanimod, did not help patients achieve disease remission in a late-stage study. Crohn’s is a chronic bowel disease causing inflammation in the digestive tract, leading to symptoms like diarrhea, abdominal pain, and fatigue. The drug, acquired through a buyout of Celgene, did not result in a significant…

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Akebia Recovers From Rejection to Win FDA Approval for Anemia Drug

Akebia Therapeutics’ drug, Vafseo, has received FDA approval for treating anemia in adults with chronic kidney disease. The drug, vadadustat, is an oral medication that mimics the effects of high altitude to stimulate the production of erythropoietin, a hormone that regulates red blood cell production. Despite safety concerns, including a black box warning for cardiovascular…

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Irish research discovers potential new multiple myeloma treatment 

Irish researchers have found a promising new treatment combination for multiple myeloma, a difficult-to-treat cancer. They discovered that combining the drug venetolax with 5-azacytidine significantly increased its effectiveness across many cancer cell lines, offering potential benefits for a broader patient population. The research, led by the RCSI Department of Physiology and Medical Physics, also showed…

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Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Researchers from Lund University in Sweden have discovered molecular signatures linked to the clinical signs of sepsis that could improve diagnosis and prognosis, as well as guide personalized treatment. Sepsis is a life-threatening condition triggered by infection that can lead to organ failure and death. Current diagnostic tests for sepsis lack accuracy, prompting the need…

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How to Transition Your Baby from a Bottle to a Cup

Transitioning from bottle to cup for your child is an important step to ensure their health and development. The American Academy of Pediatrics recommends saying goodbye to the bottle before 18 months old, with age 2 being the ideal time to make the switch. Extended bottle use is linked to tooth decay, obesity, and potential…

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To Operate or Not on Adults With Uncomplicated Appendicitis?

A meta-analysis of randomized controlled trials on the use of antibiotic therapy versus surgical treatment for uncomplicated adult appendicitis was conducted to assess safety, cost, and efficacy. Results showed a primary failure rate of 29.5% with antibiotics, increasing to 35.6% at 1 year, but no significant differences in complications or hospital stay compared to surgery….

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ChatGPT may help dental students retain knowledge and enhance performance, suggests research

Research suggests that ChatGPT, an AI-powered chatbot, can assist dental students in retaining knowledge and improving their performance. This tool may provide personalized learning experiences, answer questions, and offer explanations to help students better understand complex concepts. By utilizing ChatGPT, dental students can potentially enhance their learning experience and achieve better academic results. Furthermore, cookies…

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AliveCor Isn’t Backing Down from Apple, Its ‘Bully’

Apple has faced various legal battles, including one with medical device company AliveCor over patent infringement related to the Apple Watch. Despite Apple’s commercial success, smaller companies like AliveCor have accused Apple of stealing intellectual property. The legal issues have escalated to involve multiple lawsuits, including an antitrust case and a battle at the International…

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The Death of Social Media

Irish Medical Times is evolving from paper to cyber, citing the necessity for change and the comfort of success. The owner of the site is criticized for promoting hate and far-right ideas, leading to extreme racism and homophobia. Social media platforms like Twitter and Facebook are also under fire for allowing hate speech and harmful…

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Drug and device maker payments to doctors remain pervasive

A recent analysis found that drug and device makers have made over 85 million payments totaling $12.1 billion to 826,300 physicians from 2013 to 2022. 94% of these payments were associated with marketed medical products, including blood thinners and a robotic surgical system. 57% of all physicians received payments, with a median payment of $48…

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Canada to make contraception for women free

Canada’s government announced that it will cover the full cost of contraception for women as part of a major health care reform. This initiative will include popular contraceptive methods such as IUDs, contraceptive pills, hormonal implants, and the day-after pill for nine million Canadian women. The plan, unveiled in February, aims to be the largest…

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