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Can a Vibrating Ingestible Device Help Combat the Modern Obesity Crisis?

The obesity epidemic is a global issue with significant health implications. Innovative solutions like the vibrating ingestible device offer hope for non-invasive weight management by targeting stomach receptors to induce feelings of fullness. Although further research and human trials are needed, early results from animal studies are promising. The current COVID-19 pandemic has exacerbated obesity…

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Eko Health’s AI-enabled cardiac tool receives FDA clearance

Digital health startup Eko Health has received FDA clearance for its AI-enabled Eko Low Ejection Fraction Tool (ELEFT) that helps detect low ejection fraction, a sign of heart failure, in just 15 seconds during routine exams with an Eko stethoscope. This tool is added to Eko’s SENSORA Cardiac Early Detection Platform, which already has FDA-cleared…

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Intra-molecular compound advanced as potential disease-modifying therapy for ALS

A Cincinnati-based life sciences company, Asha Therapeutics, announced the advancement of its development candidate, ASHA-624, as a potential disease modifying therapy for amyotrophic lateral sclerosis (ALS). ASHA-624 is an intra-molecular compound that targets the SARM1 protein, which promotes axonal degeneration and neurodegeneration in ALS. Preclinical models have shown that ASHA-624 can reverse motor impairment and…

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STAT+: Roivant CEO: New deals could ‘materialize later this year’

Roivant Sciences is facing questions about whether its business model can survive its recent successes. The company’s drug brepocitinib showed positive results in a study for non-infectious uveitis, while also announcing a $1.5 billion stock buyback, including shares owned by Sumitomo. Many of Roivant’s drugs, including brepocitinib, were initially part of larger pharmaceutical companies like…

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RCGP and Faculty of Public Health top climate and health scorecard

The Royal College of General Practitioners and the Faculty of Public Health have topped the climate and health scorecard, evaluating UK health organisations’ efforts to tackle the climate emergency. 19 organizations, including nine medical royal colleges, participated in the initiative, which assesses internal operations, finance, education, and advocacy. Experts from various fields contributed to the…

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New method allows miniature robots and surgical instruments to achieve precise localization inside the body

A team of scientists from the German Cancer Research Center has developed a new method called “Small-Scale Magneto-Oscillatory Localization” (SMOL) to track and control miniature robots and surgical instruments inside the body in real-time. The method is based on a magnetic oscillator that can be excited to vibrate mechanically and then detected using magnetic sensors….

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Menopause and Anxiety: How to Manage

Rochelle Pagano, in her mid-40s, experienced anxiety and mood changes as she entered menopause. With symptoms like heart palpitations, anxiety, and depression, she realized that hormonal fluctuations were causing these issues. Lifestyle changes like healthy eating, exercise, deep breathing, meditation, and dietary supplements helped her manage her symptoms. Treatments for menopause anxiety include antidepressants, cognitive…

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FDA OKs Danicopan for Extravascular Hemolysis in PNH

The FDA has approved danicopan as an add-on therapy for patients with paroxysmal nocturnal hemoglobinuria (PNH) who are receiving ravulizumab or eculizumab. PNH is a rare blood disorder that can result in life-threatening complications such as anemia, thrombosis, and bone marrow dysfunction. Danicopan, an oral complement factor D inhibitor, helps control intravascular hemolysis and prevent…

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Can Ketogenic Diet Improve Severe Mental Illness? Pilot Study Indicates Positive Results

Researchers have found that a ketogenic diet can improve both metabolic and psychiatric symptoms in patients with serious mental illnesses like schizophrenia and bipolar disorder. These individuals often experience side effects from antipsychotic medications, such as weight gain and insulin resistance. A pilot study found that participants who followed a ketogenic diet with low carbs…

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Bengaluru Hospital, Doctor slapped compensation

A hospital in Bengaluru performed a faulty fissures operation that resulted in complications for the patient. The doctor responsible for the operation was slapped with a compensation claim as a result. The incident highlights the importance of proper medical procedures and the potential consequences of medical negligence. This case serves as a reminder for healthcare…

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Share Your Insights on the Changing Healthcare Landscape

The employee healthcare landscape is constantly evolving, with factors such as new regulations, more vendor options, and advances in technology driving the need for change. Consultants are facing challenges in meeting the diverse needs of their clients, requiring a broader knowledge base and a more expansive role. A survey is being conducted to gather insights…

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Three-in-four NCHDs feel undervalued by their employer

A survey conducted ahead of the Irish Medical Organisation’s AGM revealed that the majority of non-consultant hospital doctors feel that long hours, lack of support, and challenging working conditions are driving doctor emigration. Many NCHDs do not feel valued or supported in their work and are regularly working unsafe and illegal hours. The survey also…

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ACA Plans Are Being Switched Without Enrollees’ OK

Unauthorized enrollment or plan-switching in Affordable Care Act insurance plans is becoming a serious issue, as rogue agents can easily access policyholder accounts through the federal marketplace. This can lead to consumers being switched to different plans without their consent, causing them to potentially face issues with doctors, prescriptions, and back taxes. Federal regulators are…

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With too few pediatricians, health care costs could soar in the U.S.

The National Residency Match for medical graduates this year revealed worrying trends, particularly in the field of pediatrics. Despite an increase in applicants, a lower proportion of graduates chose pediatrics as their specialty, with nearly 30% of pediatric residency programs left unfilled. The decline in interest is attributed to low compensation for pediatricians compared to…

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‘Zombie neurons’ shed light on how the brain learns

The cerebellum, known as the “little brain,” is crucial for coordinating movement, balance, and learning. A study led by the Champalimaud Foundation reveals the importance of climbing fibers in the cerebellum for associative learning. By manipulating these fibers using optogenetics, researchers found that they are essential for teaching signals that drive learning. Surprisingly, introducing a…

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the rise of AI in neuro-oncology

A review article discusses the role of artificial intelligence (AI) in diagnosing and treating brain tumors, highlighting challenges in management and the need for precise care. Diffuse midline glioma and glioblastoma are among the toughest tumors to treat with current methods. AI offers advantages in tumor analysis, providing detailed imaging, optimized workflows, and accurate tumor…

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Treating Rheumatoid Arthritis With a Biologic: Risks and Benefits

Advancements in treatment for rheumatoid arthritis, such as biologic drugs, have drastically improved the outlook for those with the condition. Biologics, which target specific parts of the immune system, work faster and more effectively than traditional DMARDs like methotrexate. Different types of biologics are available to treat RA, including TNF inhibitors, interleukin blockers, and JAK…

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Hospitals Cash in on Concierge Care

Nonprofit hospitals originally created to serve the poor are now offering concierge physician services for annual membership fees exceeding $2000. Critics argue that this trend exacerbates primary care shortages and benefits only the affluent, driving up healthcare costs. Doctors limit their practices to a few hundred patients to provide immediate access and longer visits. Tax-exempt…

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Know Symptoms For Early Diagnosis

Autism, a developmental disability that affects behavior, communication, and learning, is important to understand on World Autism Awareness Day. It affects 1% of children globally and can last a lifetime, with symptoms varying in severity. Genetics and certain risk factors like exposure to pollution or birth complications play a role. Signs of autism include social…

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NMC Lists Down 68 Courses in 16 Medical Institutes

The National Medical Commission (NMC) has listed down 68 courses in 16 medical institutes to increase postgraduate medical seats. This move aims to address the shortage of doctors in the country. The NMC is working towards expanding the number of postgraduate medical seats to improve healthcare services. By adding more courses in existing medical institutes,…

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FDA Clears the First Digital Therapeutic for Depression, But Will Payers Cover It?

Rejoyn, a software app developed by Otsuka Pharmaceutical and Click Therapeutics, has received FDA clearance as the first prescription digital therapeutic for treating major depressive disorder. The app offers cognitive behavioral therapy lessons, exercises, and reminders in a digital format, intended for use three times weekly for six weeks. Clinical trials showed a trend favoring…

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Point-of-care brain wave monitoring can help improve concussion care

Breakthroughs in brain health, particularly in concussion assessment and treatment, have been slow despite advances in technology like MRI. Objective brain wave measures, recorded through EEG, are emerging as a priority for providing real-time insights into cognitive brain function following concussive impacts. Point-of-care EEG devices are becoming increasingly accessible, allowing for rapid assessment of concussions…

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AI deciphers city designs that could cut heart disease rates

Researchers used AI techniques to evaluate the association between built environment features identified by AI models and coronary heart disease (CHD). They used CNNs, LMEM, and activation maps to predict health outcomes at the census tract level using Google Street View images. The study found that AI algorithms could potentially reduce CHD burden by designing…

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How to Keep a Bladder Diary

Overactive bladder (OAB) is a common condition that affects many people in the United States. It can be managed through lifestyle changes, medications, treatments like Botox, nerve stimulation, and surgery. Keeping a bladder diary can help in understanding OAB symptoms, identifying behaviors that may contribute to the condition, and monitoring response to treatment. Tracking information…

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Addressing Sexual Dysfunction in Women’s Cancers

New studies suggest that many women with cancer want advice on managing sexual function issues, often not addressed by clinicians. Patients want to discuss sex but find it overwhelming at the start of their diagnosis or treatment. There is a need for more integration of sexual health screening into gynecologic oncologic clinics. Barriers to discussing…

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Combination of empagliflozin and citalopram effective against major depressive disorder: Study

A recent study found that a combination of the drugs empagliflozin and citalopram is effective in treating major depressive disorder. The researchers discovered that this combination resulted in significant improvements in depressive symptoms compared to taking citalopram alone. Empagliflozin, a medication typically used to treat diabetes, was found to enhance the effects of citalopram, an…

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Neurologic Conditions Leading Cause of Health Illness, Disability Globally

A study published in The Lancet Neurology found that conditions affecting the nervous system, such as stroke and Alzheimer’s disease, are the leading cause of disease burden worldwide. Neurodevelopmental disorders, age-related neurodegeneration, and emergent conditions like COVID-19 also impact the nervous system. The study estimated the global burden of 37 neurological disorders from 1990 to…

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Otsuka, Click Therapeutics get FDA clearance for prescription digital therapeutic

Otsuka Pharmaceuticals and Click Therapeutics have received FDA clearance for their smartphone-based prescription digital therapeutic, Rejoyn, for major depressive disorder. The six-week remote treatment program combines cognitive emotional training and therapeutic exercises to improve brain connections involved in depression. Expected to launch in 2024, Rejoyn is designed as a neuromodulatory mechanism to enhance brain function….

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Tranexamic acid may improve visualization, OR time for arthroscopic rotator cuff repair

A systematic review and meta-analysis of six randomized controlled trials showed that tranexamic acid improved visualization, operative time, and postoperative pain scores for patients undergoing arthroscopic rotator cuff repair. Researchers found that patients who received tranexamic acid had superior mean arthroscopic visual scores and lower postoperative pain scores compared to the control group. There was…

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Florida Supreme Court upholds state’s abortion ban

The Florida Supreme Court upheld the state’s ban on most abortions after 15 weeks of pregnancy, allowing a subsequent six-week ban to take effect. The court, reshaped by Governor Ron DeSantis, ruled in favor of the 15-week ban signed in 2022, which was enforced while being challenged. A six-week ban passed in 2023 will soon…

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Little guidance exists for treating inpatients with asymptomatic high blood pressure, review finds

A systematic review found that clinical practice guidelines lack guidance for managing elevated blood pressure in hospitalized patients without symptoms. This leads to inconsistent practices, with many patients experiencing higher blood pressures than recommended for outpatient care. While guidelines specify outpatient management, recommendations for inpatient care are limited to emergencies and lack instructions for transitional…

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IgA Nephropathy and Social Support

IgA nephropathy is difficult to predict, but having strong emotional and social support systems can improve long-term outcomes. It is important to maintain a fulfilling life despite the challenges of kidney disease. Peer support, such as talking to others with similar health conditions, can be beneficial. Finding kidney support groups and participating in activities with…

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A Prescription Checklist for Older Adults in ED

The GEMS-Rx list, developed by a panel of 10 ED physicians and a pharmacist, identifies high-risk medications that should not be prescribed to older patients in the emergency department (ED). This list includes first-generation antihistamines, metoclopramide, short-acting opioids, antipsychotics, barbiturates, skeletal muscle relaxants, benzodiazepines, “Z” drugs, and sulfonylureas. Exceptional cases where these medications may be…

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Search, Click, Enroll? What Clinical Trials Can Learn from E-commerce

Digital databases for clinical trials have revolutionized healthcare by providing crucial information to patients and physicians. However, the sheer size and lack of standardization in these databases can make it challenging to find relevant trials. New technological advances are being developed to improve the search process, similar to how e-commerce platforms simplify product searches. Challenges…

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St James’s launches ‘passport’ for gynaecological cancer patients

The My Gynaecology Patient Passport has been launched by an Irish hospital, St James’s Hospital, for patients with gynaecological cancer. The passport, filled in by patients and clinicians at Trinity St James’s Cancer Institute, includes important information and resources related to the patient’s diagnosis and care plan. It aims to empower patients, improve communication between…

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Viatris launches Ryzumvi for mydriasis reversal

Viatris is launching Ryzumvi, the first FDA-approved eyedrop for reversing dilation, with an onset of action in 30 minutes. The drug was approved based on positive results from two trials involving 553 patients aged 12 to 80 years. Patients who received two drops of Ryzumvi showed a significant improvement in pupil diameter compared to those…

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