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FDA Expands Benralizumab Use for Asthma to Kids Over Age 6

Benralizumab, marketed as Fasenra, has been approved by the US FDA for treating asthma in children aged 6 years and older with severe eosinophilic asthma. Originally approved in 2017 for patients aged 12 and older, the drug has shown consistent safety and tolerability in younger patients. AstraZeneca announced the expanded indication on April 11, with…

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Your Ultimate Guide To Oral Care

Maintaining optimal oral health is crucial for overall well-being due to the connection between oral health and general health conditions. Unhealthy diets, tobacco, and alcohol contribute to shared risk factors for diseases such as cardiovascular disease, cancers, diabetes, and respiratory diseases. Ameo Life Natural Mint Mouthrinse, TheraBreath Fresh Breath Oral Rinse, Listerine Ultraclean Tartar Control…

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AHA Urges Labor Department to Investigate MultiPlan’s ‘Unconscionable Practices’

The American Hospital Association is calling for the U.S. Department of Labor to investigate the business practices of MultiPlan, a data analytics firm accused of negotiating reduced reimbursements for out-of-network medical providers. The New York Times investigation revealed that the company works with major insurers such as UnitedHealthcare, Cigna, and Aetna to save billions of…

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Are COVID-19 Vaccines Safe During Pregnancy?

Getting the COVID-19 vaccine during pregnancy is safer than not getting vaccinated, according to a study published in JAMA. Research done in Sweden and Norway showed that babies born to vaccinated mothers had fewer complications and were healthier overall. The study looked at nearly 200,000 newborns and found that those exposed to the vaccine in…

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Arizona Turns Back the Clock on Abortion Access

The Arizona Supreme Court upheld a ban on abortion, sparking debate on the issue. Former President Trump expressed support for states’ rights on abortion while criticizing the ruling. The panelists discussed Trump’s shifting views on abortion and the potential impact of the Arizona ruling. Another court in Indiana ruled against an abortion ban that violated…

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The Cass review: an opportunity to unite behind evidence informed care in gender medicine

Hilary Cass’s review of gender identity services in the NHS emphasizes the importance of providing high-quality care for children and young people experiencing gender dysphoria. The evidence base for interventions in gender medicine is found to be lacking, with low methodological rigor in studies on puberty blockers and hormone treatment. Cass recommends confining prescription of…

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A new diagnostic model offers hope for Alzheimer’s

A new personalized mathematical model called the Alzheimer’s Disease Biomarker Cascade (ADBC) has been developed using real-world data from over 800 people with varying cognitive abilities. The model incorporates individual biological markers to predict disease progression and response to treatment. It analyzes cerebrospinal fluid, brain scans, and memory tests to identify unique patterns in each…

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Annual COVID-19 vaccine proves to be a wise investment for personal health and pocketbook

A recent study examined the economic benefits of annual COVID-19 vaccination for adults in the United States. With decreasing government support and lower disease severity, researchers analyzed individual benefits from getting the vaccine annually. Using a computational simulation model, they found that vaccinated adults aged 18-49 could save $30-$603 without insurance and $4-$437 with insurance….

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How to Manage Life With Children With ADHD

Penny Williams, a parenting coach and author, recalls the struggles of parenting her son with ADHD. She emphasizes the importance of resources, support, and understanding for parents with neurodiverse children. Strategies for managing ADHD include a mix of medication, lifestyle changes, parent mindset, and coping mechanisms. Practical tips include using Point of Performance reminders, motivation…

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Short, Frequent Walks Improve Cardiovascular Profile in T1D

A study on people with type 1 diabetes found that breaking up long sitting periods with short, frequent walks can reduce postprandial vascular inflammatory biomarkers. The SIT-LESS trial involved 32 inactive individuals who either sat for 7 hours or took light walks every 30 minutes after meals. Those who walked had lower levels of inflammatory…

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The Top 7 Meal Replacement Shakes For Busy Lifestyles

Meal replacement shakes are ideal for those on the go or on a wellness journey, replacing a meal with fewer calories but packed with nutrients and proteins. Choosing the right brand can be challenging, considering your nutritional needs and protein content. Some top picks include Almased, which aids in weight loss and overall well-being; Ka’Chava,…

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Acetaminophen use during pregnancy not tied to children’s risk of autism, ADHD, and intellectual disability: JAMA

A study published in JAMA found that the use of acetaminophen during pregnancy is not associated with an increased risk of autism, ADHD, or intellectual disability in children. The study concluded that there is no significant link between acetaminophen use during pregnancy and these developmental disorders. This information is important for pregnant women who may…

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Professor Garry Courtney

In the latest episode of Irish Medical Lives, Dr. Chris Luke interviews Professor Garry Courtney, a Consultant Gastroenterologist and Clinical Director at St. Luke’s Hospital in Kilkenny. Prof. Courtney holds various leadership roles in the medical field and discusses his background in medicine, including his time as a medical student at Trinity College in Dublin….

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European Parliament votes in favor of updated pharma legislation

The European Parliament has voted on legislation that aims to change the way medicines are brought to market and accessed in Europe. The pharmaceutical industry and consumer groups have mixed reactions towards the legislation, particularly regarding data protection. The debate revolves around the length of time generic companies are prohibited from using study data from…

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AI model has potential to detect risk of childbirth-related PTSD

Researchers have developed an AI program that can identify signs of childbirth-related post-traumatic stress disorder (CB-PTSD) by analyzing short narratives from patients who have given birth. The program successfully identified a large number of participants likely to have CB-PTSD, indicating the potential for rapid and cost-effective screening for the disorder. Untreated CB-PTSD can have negative…

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Metrion Biosciences enhances High Throughput Screening services with access to Enamine compound libraries

Metrion Biosciences Limited and Enamine Ltd have partnered to enhance Metrion’s High Throughput Screening (HTS) services with access to Enamine’s compound libraries. Enamine’s collection is the largest globally, offering both CNS and ion channel-focused target libraries. These libraries can be split into screening sets for increased flexibility, efficiency, and cost-effectiveness in hit expansion and SAR…

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How Your ‘Sleep Style’ Can Determine Your Long-Term Health

Ryan Wong, a human resources manager, struggled with sleep until he prioritized improving his nighttime routine, leading to better rest. Penn State University research identified four “sleep types,” linking poor sleep to chronic conditions like diabetes and depression. Other studies found sleep issues in middle age can contribute to cognitive decline and brain health problems…

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High-Dose Valproate Linked to Significant Weight Gain

A study found that high-dose valproate is associated with weight gain in psychiatric patients, with the greatest gain reported in those taking ≥ 1300 mg/d. The study included 215 patients with various psychiatric diagnoses. Each 500-mg increase in valproate dose was associated with a weight increase of 0.52% per month over a year. Weight gain…

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Deputy Chief Medical Officer – Department of Health

The Department of Health aims to improve health and wellbeing in Ireland by providing the right care at the right time and place. The Chief Medical Officer offers expert advice on health and wellbeing, bioethics, and health policy development. The Deputy Chief Medical Officer supports these functions and must have registration on the Specialist Register…

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New York Digital Media Campaign Does Not Improve Duration of Untreated Psychosis

A digital media campaign in New York aimed to engage young individuals with early psychosis online, but did not result in significant improvements in treatment initiation or duration of untreated psychosis. The campaign targeted FEP programs and individuals with suspected CHR or psychotic disorders, with 371 individuals proceeding to remote clinical assessment. Despite efforts, there…

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Google Cloud partners with Bayer for AI applications for radiology

Google Cloud and Bayer are collaborating to develop AI applications to reduce radiologist burnout and improve diagnoses. Bayer will use Google Cloud’s technology, including generative AI tools, Vertex AI, BigQuery, Healthcare API, and Chronicle to expand its innovation platform. The aim is to help organizations create scalable and compliant AI-enabled software for medical imaging while…

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Studies show ChatGPT provides reliable information on vaccines, STIs

ChatGPT, a free AI system, has shown potential in healthcare, including providing accurate information on vaccines and STIs. Two studies presented at the ESCMID Global Congress found that ChatGPT could help reduce vaccine hesitancy and increase STI awareness. The system accurately responded to questions about vaccines and sexual health, performing at the level of professional…

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Drug shortages reached a record high as 2023 drew to a close

The U.S. is currently facing 323 ongoing drug shortages, the highest number since tracking began in 2001. These shortages are concerning due to the potential harm to patients. Basic and life-saving medicines like oxytocin, Rho(D) immune globulin, chemotherapy, pain/sedation medications, and ADHD pills are in short supply. The reasons for these shortages are varied and…

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Efficacy of a single low dose of esketamine after childbirth for mothers with symptoms of prenatal depression: randomised clinical trial

This study was a randomised, double blind, placebo controlled trial conducted in five hospitals in China to assess the effects of low dose esketamine on postpartum depression. Pregnant individuals with Edinburgh postnatal depression scale scores of ≥10 were enrolled and administered either esketamine or a placebo. The primary endpoint was the prevalence of major depressive…

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How to Get Your Child Involved

Parents understand that regular house cleaning helps prevent illnesses in children. Older children can start helping with chores, but parents should be honest and use logic rather than commands. Turning chores into a game can motivate younger children, but parents should avoid pitting siblings against each other. Rewards for helping with chores should be promised…

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Substantial Triglyceride Reduction With Plozasiran

Plozasiran, an investigational drug, significantly reduced triglyceride levels in patients at risk for pancreatitis. In the phase 2 SHASTA-2 study, most patients saw their levels fall below the pancreatitis risk threshold after receiving plozasiran injections. The drug’s safety profile was generally favorable, but it did lead to increased LDL cholesterol and a temporary decline in…

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Trials of Psychological Interventions for Depression Rarely Assess Suicidality

A systematic review and meta-analysis published in The Lancet Psychiatry found that clinical trials of psychological interventions for depression often do not assess suicidality, despite the known association between depression and suicide risk. Most trials did not include assessments for suicide, with only a small number reporting on suicidal thoughts and behaviors as adverse events….

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Attack of the Medicare Machines

In this episode of “An Arm and a Leg,” host Dan Weissmann explores the dark side of the American health care system, focusing on Medicare Advantage plans using an algorithm owned by UnitedHealth Group to make decisions about patient care. This algorithm has caused people to be prematurely discharged from nursing homes, leading to adverse…

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Medical cannabis use decreased in states where recreational use is legalized, study shows

Enrollment in medical cannabis programs increased by 33% from 2020 to 2022, but decreased in states where nonmedical adult use was legalized. The prevalence of medical cannabis use among U.S. citizens has increased significantly in the past decade. A study found that patient enrollment dropped dramatically in some states following the legalization of nonmedical adult-use…

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