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Novel Antibiotic To Treat Drug-Resistant Bacteria? Zosurabalpin Shows Promising Results In Mice

Scientists have developed a new antibiotic, Zosurabalpin, to treat drug-resistant bacteria that cause deadly infections in humans. This antibiotic has shown promising results in treating highly drug-resistant strains of Carbapenem-resistant Acinetobacter baumannii (CRAB) in mouse models. CRAB is a pathogen resistant to almost all antibiotics and responsible for deadly infections in the blood, urinary tract,…

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With Medical Debt Burdening Millions, a Financial Regulator Steps In to Help

President Obama established the Consumer Financial Protection Bureau in 2010 to prioritize consumer protection over the interests of big banks. The CFPB has shifted its focus to addressing medical debt issues, penalizing collectors, warning providers, and developing rules to remove medical debt from credit reports. This move has faced opposition from collectors and legal challenges….

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Atlas Venture raises $450 million fund

Atlas Venture, a prominent venture capital firm in the biotech industry, has raised $450 million for its 14th fund. The fund will focus on seed and series A rounds for biotech companies, with Atlas often playing a role in creating these companies. Unlike other firms, Atlas does not usually accept pitches from outside entrepreneurs, but…

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Online Skin Cancer Depictions on Darker Skin Tones Limited

Darker skin tones were underrepresented in images on patient-facing online educational material about skin cancer, an analysis of photos from six different federal and organization websites showed. Given the known disparities patients with darker skin tones face in terms of increased skin cancer morbidity and mortality, this lack of representation further disadvantages those patients by…

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How did the COVID-19 pandemic affect older adults’ technology use?

The COVID-19 pandemic forced many older adults to adopt technology for social interactions, leading to changes in how they communicated within their support networks. A study by University of Washington researchers found that older adults not only received support through technology but also provided support, including emotional, financial, and physical assistance. The research emphasized the…

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Reversing adipose tissue fibrosis through targeted microRNA therapies

, 2025-04-20 17:19:00 A new review published in Genes & Diseases highlights the transformative role of microRNAs (miRNAs) in regulating and potentially reversing adipose tissue fibrosis, a condition closely linked to obesity, diabetes, and cardiovascular disease. Fibrosis, driven by abnormal extracellular matrix (ECM) accumulation, disrupts normal adipose tissue function and contributes to broader organ dysfunction….

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Bidirectional association found between rheumatoid arthritis, COPD

A review published in Frontiers in Immunology found a bidirectional association between rheumatoid arthritis (RA) and chronic obstructive pulmonary disease (COPD). The analysis included 19 studies with 1,549,181 participants, showing a significant association between RA and increased COPD risk. Likewise, individuals with COPD had an increased risk for RA, particularly among women and in cohort…

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Colchicine Drug Interactions May Not Affect Safety, Efficacy

The presence of drug-drug interactions (DDIs) did not increase the risk for colchicine-related gastrointestinal adverse events or impact the effectiveness of colchicine in ambulatory patients with COVID-19, according to a study conducted by Lama S. Alfehaid, PharmD. A total of 4432 patients were given colchicine or a placebo, with a small percentage having potential DDIs….

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Eating disorders: Targets fail to improve children’s access to treatment, warn psychiatrists

response to this urgent need, the Royal College of Psychiatrists is calling on the government to invest in expanding children’s eating disorders services. This includes increasing the number of child and adolescent psychiatrists specializing in eating disorders to address staff shortages. The current lack of capacity in the NHS results in children facing physical and…

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Expert Tips for Managing GLP-1 Medication Side Effects

Glucagon-like peptide 1 (GLP-1) medications are effective weight loss tools for obese individuals, but many patients struggle with side effects such as nausea, vomiting, constipation, and dehydration. Adjusting the dosage gradually and following a diet rich in fiber and smaller, easily digested meals can help manage these side effects. Hydration and avoiding heavy, fatty foods…

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Advanced tools offer improved insights into brain injury patients’ condition and their potential for recovery

, 2025-05-20 22:30:00 Credit: Unsplash/CC0 Public Domain Trauma centers nationwide will begin to test a new approach for assessing traumatic brain injury (TBI) that is expected to lead to more accurate diagnoses and more appropriate treatment and follow-up for patients. The new framework, which was developed by a coalition of experts and patients from 14…

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Some Medicaid Providers Borrow or Go Into Debt Amid ‘Unwinding’ Payment Disruptions

Assisted living facilities in Montana are facing financial struggles due to delays in Medicaid payments for residents. Providers are waiting for payments ranging from weeks to months, leading to financial strain and challenges in providing care. The state’s Medicaid redetermination process has caused disruptions in payments to providers, affecting long-term care facilities, substance use disorder…

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Lateral episiotomy or no episiotomy in vacuum assisted delivery in nulliparous women (EVA): multicentre, open label, randomised controlled trial

This study conducted in Sweden aimed to determine the effect of lateral episiotomy compared to no episiotomy on obstetric anal sphincter injury in nulliparous women undergoing vacuum extraction. A total of 717 women were included in the study, with half assigned to lateral episiotomy and the other half to no episiotomy. The results showed that…

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Geron Drug Lands a First-in-Class FDA Approval in Type of Blood Cancer

The FDA has approved Geron Corporation’s drug, imetelstat, for the treatment of anemia in adults with low- to intermediate-risk myelodysplastic syndromes. This marks the company’s first commercialized product and provides competition against Bristol Myers Squibb’s blockbuster drug. The approval is based on the drug’s ability to enable bone marrow recovery and normal red blood cell…

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Readout Newsletter: Moderna, Vertex, Otsuka, Vera

Damian bids farewell in the final edition of The Readout at STAT after 8 years of covering biotech. Meghana Keshavan will continue the newsletter. European regulators find no link between new obesity medicines and suicidal thoughts. Moderna halts plans to invest in a Kenya manufacturing site for mRNA vaccines due to insufficient demand. Vertex Pharmaceuticals…

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‘Unprecedented’ results for CAR-T cells in lupus may signify new era in treatment

At a recent symposium, William Rigby, MD, discussed the unprecedented efficacy of chimeric antigen receptor T-cell therapy in lupus patients, reporting almost complete disappearance of symptoms. However, long-term impacts remain to be seen, as B-cell responses eventually returned. Rigby presented findings from a study that showed that CAR-T cell therapy was more effective than other…

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New Drug Prevents Severe RSV in Infants

Joanna Mulvaney PhD , 2025-05-01 14:24:00 A study published this morning in the Lancet Child and Adolescent Health, announces that the monoclonal antibody, nirsevimab, prevents severe respiratory syncytial virus infections in infants. In a huge review of the published evidence, epidemiologists from University of Toronto and York University, Toronto, tracked how effective nirsevimab was when…

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Immigration Detention Center Contractor Sues Over California Health Inspections

Private prison contractor GEO Group filed a lawsuit against California officials over a state law allowing public health inspections at immigration detention facilities. The company claims the law is unconstitutional and interferes with federal immigration enforcement. The lawsuit names Gov. Gavin Newsom, Attorney General Rob Bonta, and a health officer as defendants. GEO’s stock rose…

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In Real World, Patients With Myeloma Have Worse Outcomes

A study found that patients with multiple myeloma had dramatically worse outcomes in real-world settings than in clinical trials. Patients in the real-world experienced worse progression-free and overall survival on six of seven standard treatments compared with those in clinical trials. The analysis included nearly 4000 patients with multiple myeloma and compared real-world outcomes with…

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Innovations in Treating Vitiligo

Vitiligo is an autoimmune disease that causes depigmentation of the skin, affecting 0.5% to 2% of the population. It can have a significant psychological impact on patients and affects people of all ethnic groups. Treatments include immunosuppressant medications, phototherapy, and laser treatments. Recent research has led to the development of promising new drugs that target…

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PharmaKure granted MHRA Clinical Trial Authorisation (CTA) for PK051 for the treatment of mild cognitive impairment due to Alzheimer’s Disease

PharmaKure has received approval from the UK MHRA to begin a Phase 2a study for its drug PK051, intended for the treatment of mild cognitive impairment (MCI) due to Alzheimer’s Disease. PK051 is an oral combined drug that targets the disaggregation of amyloid-β proteins, believed to be the initial event in Alzheimer’s Disease pathology. The…

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Augmented Assistant Robots (AAR) Unveils A New Era In Robotic Surgery

The AAR Surgical Robotics Complex by Augmented Assistant Robots aims to revolutionize robotic surgery by addressing common challenges faced by surgeons. It focuses on affordability, precision, and accessibility, with the goal of democratizing access to top-tier medical care globally. The complex features innovative technologies such as single-use instruments, multi-directional manipulators, and remote control capabilities for…

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Costly U.S. health care system could take lessons from Portugal

Portugal’s health system focuses on primary care and public health, leading to longer life expectancy and lower healthcare costs compared to the U.S. The country’s success is attributed to a national health care system that provides free or low-cost healthcare to all residents. Portugal implements innovative programs like “social prescribing” and has effectively addressed drug…

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Novavax COVID vaccine moves closer to full FDA approval

, 2025-04-25 16:58:00 by I. Edwards Novavax’s COVID-19 vaccine could soon receive full approval from the U.S. Food and Drug Administration (FDA), the company said Wednesday. The update sent Novavax’s stock up more than 21% in early trading. It also helped ease fears that the decision had been delayed by the Trump Administration, The Associated…

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All About the (Government) Funding

Lawmakers are struggling to fund the government and federal health programs. The Supreme Court is reviewing a case about Idaho’s abortion ban and federal law. The Biden administration is scaling back health provider conscience protections. Florida introduced legislation classifying abortion as a felony and penalizing those involved in distributing abortion pills. The FDA approved Florida’s…

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Poor Nutrition Status, High Sarcopenia Rates

, 2025-04-25 12:00:00 TOPLINE: Patients with inflammatory bowel disease (IBD) showed significantly lower muscle strength than matched healthy individuals, with women showing particularly worse nutritional status in terms of fat-free body mass and muscle mass and a higher incidence of sarcopenia. METHODOLOGY: Researchers conducted a case-control study comparing the nutritional status of 80 adults with…

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A Sneak Peek Into Future Testing For Multiple Sclerosis

Doctors may soon be able to use blood tests to predict how primary progressive multiple sclerosis (PPMS) will worsen overtime for patients.1 This opens the door to earlier interventions and personalized treatment plans, eventually creating opportunities to slow the progression of the disease. Primary progressive multiple sclerosis is a specific type of multiple sclerosis (MS)…

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Do GLP-1s Lower CRC Risk in Patients With Obesity and T2D?

, 2025-05-07 07:53:00 SAN DIEGO — Patients with obesity and type 2 diabetes treated with glucagon-like peptide 1 (GLP-1) receptor agonists had significantly reduced rates for colorectal cancer (CRC) risk and associated mortality compared with those undergoing bariatric surgery, new research showed. CRC risk was also lower for patients taking GLP-1s than the general population….

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Taking Pills For Cardiovascular Diseases? They May Also Protect Against Dementia, Study Says

Researchers from the Karolinska Institutet in Sweden have found that long-term use of common cardiovascular drugs may offer protection against dementia. The study, which involved 88,000 individuals over 70 years old, found that using antihypertensive drugs, cholesterol-lowering drugs, diuretics, and blood-thinning drugs for more than five years was associated with a lower risk of dementia….

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Young Gay Latinos See Rising Share of New HIV Cases, Leading to Call for Targeted Funding

Fernando Hermida sought asylum in the U.S. and was diagnosed with HIV in January 2022. Despite efforts to address the HIV epidemic, Latino communities are experiencing disproportionate rates of new infections and diagnoses. Latino health policy advocates call for more funding and targeted outreach to address the issue. Hermida struggled with navigating the healthcare system,…

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