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ADVANCE-HTN Shows Benefit of Lorundrostat in Resistant Hypertension

Summarize this content to 100 words The addition of lorundrostat, an investigational drug, to the treatment regimen of people with well-treated but uncontrolled and resistant hypertension could be beneficial, new data show.”Lorundrostat effectively lowered blood pressure with an acceptable side effect profile,” said Luke Laffin, MD, a cardiologist at the Cleveland Clinic, Ohio, who presented…

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The Giants Foundation and American Heart Association promote life-saving CPR skills

Summarize this content to 100 words The American Heart Association and The Giants Foundation, the nonprofit organization of the New York Giants, gathered representatives from 12 local schools for cardiopulmonary resuscitation (CPR) and automated external defibrillator (AED) training on March 20 at MetLife Stadium. According to American Heart Association data, nearly 9 out of 10 people…

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The Colorado psychedelic mushroom experiment has arrived

Summarize this content to 100 words Credit: Unsplash/CC0 Public Domain Colorado regulators are issuing licenses for providing psychedelic mushrooms and are planning to authorize the state’s first “healing centers,” where the mushrooms can be ingested under supervision, in late spring or early summer. The dawn of state-regulated psychedelic mushrooms has arrived in Colorado, nearly two…

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Confronting the shortcomings of covid-19 vaccination will help us in future pandemics

Summarize this content to 100 words Samantha Vanderslott, associate professor and career development fellowPandemic Sciences Institute, University of OxfordWe must learn from the successes and failures of the covid-19 vaccination programme if we are to prepare for the next pandemic, writes Samantha VanderslottVaccination has been so successful in protecting whole populations from disease that it…

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Novel Agent Curbs Alzheimer’s-Related Agitation

Summarize this content to 100 words Treatment with AXS-05, a combination of dextromethorphan and bupropion, demonstrated rapid, sustained, and clinically meaningful improvement in agitation related to Alzheimer’s disease (AD) and was generally well tolerated in the phase 3 ACCORD trial. More than half of participants in the open-label extension period of the randomized clinical trial responded…

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Headspace launches direct-to-consumer mental health coaching

Summarize this content to 100 words Digital mental health company Headspace announced it will offer direct-to-consumer mental health coaching to its subscribers, with therapy offerings becoming available later this year.  U.S. subscribers will have access to a mental health coach within the company’s app for issues that may not require a therapist, such as getting…

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FDA approves Day One’s drug for common childhood brain tumor

Summarize this content to 100 words Day One Biopharmaceuticals said Tuesday the Food and Drug Administration approved its pill for one of the most common forms of childhood brain tumors, called pediatric low-grade glioma. The authorization is particularly notable because industry has historically developed few drugs for children with cancer, focusing instead on adults and…

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Avoidance Predicts Worse Long-term Outcomes in OCD

Summarize this content to 100 words BOSTON — Behavioral avoidance could limit the long-term efficacy of exposure and response prevention (ERP), a widely used treatment for obsessive compulsive disorder (OCD), a new analysis shows. Although avoidant patients with OCD reported symptom improvement immediately after treatment, baseline avoidance was associated with significantly worse outcomes 1 year later. “Avoidance…

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Don’t Let Inflation Bloat Your Drug Spending

Summarize this content to 100 words Inflation has made drug prices as eye popping as grocery prices and has hurt hospitals as much as households. In both cases, smarter shopping can ease the pain. From 2022 to 2023, drug prices surged by an alarming 15.2%, on average, on top of an 11.2% increase the previous…

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Audit of potential organ donors to rollout across country

Summarize this content to 100 words Auditing of organ donation practices and processes will soon be rolled out across the country after the process showed promise in increasing donor opportunities. The Irish Potential Donor Audit (IPDA) aims to identify donors at the time of death, and promotes best practice in how healthcare staff reach out…

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NIH: Havana Syndrome Still a Mystery

Summarize this content to 100 words “It was like a high-pitched, metallic drilling noise. . .it knocked me forward,” said FBI agent, “Carrie,” as she described what she believed to be the impetus behind her illness—a strange condition colloquially referred to as “Havana Syndrome.”1 First reported by US embassy employees in Havana, Cuba in 2016 (and possibly…

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ABOUT Healthcare acquires AI analytics company Edgility

Summarize this content to 100 words Patient management company ABOUT Healthcare announced it acquired AI analytics platform Edgility, enabling ABOUT to offer patient progression solutions with predictive and prescriptive analysis.  ABOUT Healthcare, formerly Central Logic, provides a product care suite that allows it to move patients in and out of various care settings, such as…

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Standardising antenatal analgesia information | The BMJ

Summarize this content to 100 words Adam G Mounce, anaesthetic core traineeDepartment of Anaesthetics, Prince Charles Hospital, Merthyr Tydfil, UKagmounce{at}doctors.org.ukKmietowicz reports that women from poorer backgrounds are less likely to have an epidural during labour than women from richer backgrounds, even when it is medically indicated.1The authors of the study published in Anaesthesia suggest several…

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Charting brain synchronization patterns during social interactions

Summarize this content to 100 words Study finds that interaction between strangers leads to higher levels of inter- and intra-brain synchronization compared to that in close acquaintances. Credit: Yuto Kurihara from Waseda University We experience the world and connect with others through social interactions. Engaging in activities, such as conversations, cooperative tasks, and intimate relationships,…

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Europe Approves Paroxysmal Nocturnal Hemoglobinuria Drug

Summarize this content to 100 words The first-in-class complement factor D inhibitor danicopan (Voydeya) has been approved by the European Commission as an add-on agent for certain patients with the rare disease paroxysmal nocturnal hemoglobinuria (PNH).PNH is a rare, chronic, progressive, multisystemic disease caused by an acquired genetic mutation of the X-linked gene PIGA. The…

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The FDA accelerated approval pathway works — but it isn’t flawless

Summarize this content to 100 words The Food and Drug Administration’s accelerated approval program aims to speed “approval of drugs that treat serious conditions, and fill an unmet medical need based on a surrogate endpoint” of overall survival (progression-free survival). Overall survival is usually considered the gold standard in oncology because people with cancer generally…

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Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Summarize this content to 100 words With malaria still posing a constant and often deadly threat to billions worldwide, new therapies are urgently required to combat the infection. This is made more difficult by the multiple stages of the parasite’s lifecycle. A new report in Scientific Advances reports on tafenoquine, a prodrug that could fulfill…

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Review Examines Hyperemesis Gravidarum Diagnosis, Treatment

Summarize this content to 100 words Researchers have reviewed the evidence related to hyperemesis gravidarum and provided guidance for the diagnosis and treatment of this condition.Hyperemesis gravidarum, or severe nausea and vomiting in pregnancy, can have detrimental effects on maternal quality of life and on the patient’s children. The review provided an overview of the…

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Biden admin issues rule protecting abortion privacy

Summarize this content to 100 words Credit: Unsplash/CC0 Public Domain President Joe Biden’s administration announced a new rule Monday to protect the privacy of women who go out of their home state to have legal abortions, amid fears they could be prosecuted upon their return. The move comes as reproductive rights take center stage in…

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Sapio Sciences Launches New Multimodal Registration Capabilities

Summarize this content to 100 words Sapio Sciences has enhanced its lab informatics platform with new multimodal entity registration capabilities for diverse product types, including small and large molecules and conjugates. Image Credit: Sapio Sciences BALTIMORE, MD, April 23, 2024 — Sapio Sciences, the science-awareTM lab informatics platform, today announced the launch of its new multimodal…

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Less Gut Microbial Diversity in Patients With Prediabetes

Summarize this content to 100 words TOPLINE:The gut microbiome biodiversity is lower in patients with prediabetes than in healthy individuals, and the microbiota have less of the species involved in key physiology and metabolism roles.METHODOLOGY:The association between gut bacteria, diet, glucose metabolism, and insulin resistance has been established, but there is a lack of research…

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A Common Antibiotic Could Prevent, Treat Respiratory Illnesses Including COVID-19: Study

Summarize this content to 100 words A range of respiratory illnesses including COVID-19 and influenza could be prevented and treated using a widely available generic antibiotic, the results of a new study revealed.A team of researchers from Yale tested the effectiveness of antibiotic neomycin in animal models and found that administering the antibiotic neomycin through…

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Health Bulletin 23/ April/ 2024

Summarize this content to 100 words Health Bulletin 23/ April/ 2024 We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok Source link

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