2025

Yegor Tsynkevich , 2025-04-21 14:50:00 Healthcare innovation is frequently accompanied with skepticism and resistance, even when it promises to improve patient outcomes and operational efficiency. Healthtech companies prioritize clinical validation, regulatory approvals, and performance metrics to ensure their technology meets industry standards. However, they often overlook one crucial factor: clinician adoption. Even the most promising…

Sanjeev Bhatia, MD; David B. Mandell, JD, MBA; Bob Peelman , 2025-04-21 14:28:00 April 21, 2025 4 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on ….

Meghana Keshavan , 2025-04-21 13:36:00 Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Morning. Today, we talk lots about tariffs — how they might impact drugmakers, patients, and even Ireland. Also, Novo Nordisk challenges Medicare over drug differentiation, and more.  Tariffs threaten…

, 2025-04-21 13:46:00 Virginia Tech researchers John Janiga, Dzenis Mahmutovic (seated), Katherine Brown, and lead investigator Carla Finkielstein work together in the Molecular Diagnostics Laboratory at the Fralin Biomedical Research Institute at VTC to develop a test that could help doctors identify cancer patients at risk for severe chemotherapy side effects. Credit: Clayton Metz/Virginia Tech…

, 2025-04-21 13:49:00 Ticks are more likely to carry the bacteria that can cause Lyme disease in areas where pheasants are released, new research shows. Pheasants are not native to the UK, but about 47 million are released here each year for recreational shooting. Researchers studied ticks in 25 woodland areas in South West England…

, 2025-04-21 12:22:00 A recently released statement on Trump administration’s drug policy priorities called for a focus on stopping illicit drugs from coming into the United States, prosecuting those responsible for overdose deaths, expanded access to naloxone, and new campaigns “to inform the American people of the dangers of illicit drug use, the hope of…

Gabrielle M. Grasso , 2025-04-21 13:00:00 April 21, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to…

Jason Mast , 2025-04-21 13:05:00 Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds. Sign up here. Good morning, Jason Mast here filling in for Theresa. The Morning Rounds editor has informed me that she has tired of all this debate over potato chips and the curious case of…

, 2025-04-21 12:38:00 The CoNav autonomous wheelchair developed by U-M engineers gives users the option of taking control. Credit: Vineet Kamat, Carol Menassa Autonomous technologies promise passengers travel without concern—the ability to get from Point A to Point B without needing to be engaged in the process. Yet passengers still don’t trust computers the way…

, 2025-04-21 12:29:00 CHICAGO — For patients with advanced heart failure, an injection of autologous mononuclear cells into damaged myocardia missed the primary endpoint in the sham-controlled, randomized, blinded CardiAMP-HF trial, but there was a strong signal of benefit, supporting further assessment. The study had a hierarchical win-ratio design, and the intervention met two of…

Stephanie Baum , 2025-04-21 11:30:00 The healthcare investor conference MedCity INVEST, scheduled for May 20-21 at the Willis Tower in Chicago, will spotlight strategic priorities for health systems at a time when many face uncertainty amidst dramatic changes at HHS and with government funding at risk. A panel discussion on the strategic priorities of health…

Paula Span , 2025-04-21 09:00:00 Paula Span The assisted living facility in Edina, Minnesota, where Jean Peters and her siblings moved their mother in 2011, looked lovely. “But then you start uncovering things,” Peters said. Her mother, Jackie Hourigan, widowed and developing memory problems at 82, too often was still in bed when her children…

Isabella Hornick , 2025-04-21 11:42:00 April 21, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…

Adam Feuerstein , 2025-04-21 11:00:00 Adam Feuerstein is a senior writer and biotech columnist, reporting on the crossroads of drug development, business, Wall Street, and biotechnology. He is also a co-host of the weekly biotech podcast The Readout Loud and author of the newsletter Adam’s Biotech Scorecard. You can reach Adam on Signal at stataf.54….

, 2025-04-21 11:14:00 Credit: The FASEB Journal (2025). DOI: 10.1096/fj.202402942R A protein that stops cells from dividing in response to damage or stress could be a new biomarker or therapeutic target for metabolic dysfunction-associated steatotic liver disease (MASLD), according to research published in The FASEB Journal. The protein, called cyclin-dependent kinase inhibitor 1A (CDKN1A), was…

, 2025-04-21 10:46:00 California has halted a court-ordered medical parole program, opting instead to send its most incapacitated prisoners back to state lockups or release them early. The unilateral termination is drawing protests from attorneys representing prisoners and the author of the state’s medical parole legislation, who say it unnecessarily puts this vulnerable population at…

, 2025-04-21 10:26:00 Despite guidelines stating otherwise, clinicians continue to prescribe inappropriate antibiotics to hospitalized patients with skin and soft tissue infections (SSTIs), raising costs and increasing the risk for drug-resistant organisms. A new study has found that computer-assisted recommendations, coupled with targeted best practices, significantly reduce the use of extended-spectrum antibiotics, all without increasing…

, 2025-04-21 09:32:00 Born twice? It sounds impossible, but that’s exactly the story of miracle baby Rafferty Isaac in the U.K. At just 20 weeks, he was temporarily removed while in the womb so doctors could perform life-saving surgery on his mother, who had been diagnosed with ovarian cancer. After the complex five-hour procedure, Rafferty…

Don Thompson , 2025-04-21 09:00:00 SACRAMENTO, Calif. — California has halted a court-ordered medical parole program, opting instead to send its most incapacitated prisoners back to state lockups or release them early. The unilateral termination is drawing protests from attorneys representing prisoners and the author of the state’s medical parole legislation, who say it unnecessarily…

Josh Friedman , 2025-04-21 09:00:00 April 21, 2025 6 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…

Andrew Joseph , 2025-04-21 08:30:00 The hulking factories are tucked away off the roads around the village of Ringaskiddy — operated by the likes of Pfizer, Johnson & Johnson, and BioMarin, whose plant featured signs last week touting a new facility “coming Q1 2027.” The nearby town of Carrigtwohill crows that it’s grown “+400% over…

, 2025-04-21 09:00:00 Credit: Unsplash/CC0 Public Domain Older adults with cancer respond just as well as younger patients to immune checkpoint inhibitors despite age-related immune system differences, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy, and the Johns Hopkins Convergence Institute. Most new…

, 2025-04-21 09:04:00 TOPLINE: A recent study found that the homeostasis model assessment insulin resistance (HOMA-IR), quantitative insulin-sensitivity check index (QUICKI), and fasting glucose/insulin ratio (FGIR) were stronger predictors of insulin resistance than the triglyceride glucose index (TyG) in children with overweight or obesity. METHODOLOGY: Researchers conducted a single-center retrospective study to establish the correlation…

, 2025-04-21 08:32:00 Three cases of Creutzfeldt-Jakob Disease (CJD), a rapidly progressing illness that leads to dementia and death, have been reported in Oregon, officials revealed. Source link

Hala Durrah , 2025-04-21 08:30:00 Democrats recently unveiled a campaign to recruit and elect 100 doctors to public office. Democrats hope that by recruiting physicians to public office, they will be able to combat misinformation and restore trust in medicine and science.  Amid a full-blown measles outbreak, the U.S. plan to withdraw from the World…

, 2025-04-21 07:31:00 The Layer 7 Cortical Interface is a high-resolution cortical electrode array for use in recording, monitoring, and stimulating electrical activity on the surface of the brain. Medscape Medical News Source link

, 2025-04-21 07:16:00 TOPLINE: In patients with nasopharyngeal carcinoma who received induction-concurrent (chemo)radiotherapy, persistent Epstein-Barr virus (EBV) DNA positivity or its resurgence during treatment was associated with worse survival outcomes, whereas rapid clearance of EBV DNA following induction chemotherapy was associated with better survival. METHODOLOGY: Plasma EBV DNA is the most widely used biomarker for…

, 2025-04-21 07:04:00 Amid growing fears over a surge in measles cases in Texas, a video circulating online has sparked outrage after it showed a doctor with a measles rash treating children. Public health experts have raised alarms about the potential spread, condemning the doctor who continued to practice while being infected with the highly…

, 2025-04-21 06:24:00 The story of how Erin McKean, MD, ended up in, as she puts it, the “weird small niche field” of minimally invasive, ventral skull base surgeries — operating on sinonasal cancers and pituitary tumors for instance — might never have happened had she not met her mentor. The first in her family…

, 2025-04-21 06:30:00 The Centers for Disease Control and Prevention confirmed its first US case of COVID-19 in early 2020, and 8 months later the World Health Organization described a post-viral condition called long COVID. Since then, millions of Americans, around 8% of those with acute COVID, have also been identified as having long COVID….

, 2025-04-21 06:21:00 Immanuel Hoxobeb assists Alicia who participates in the “Enabling Through the Horse,” therapy program outside Windhoek, Namibia, on Feb. 18, 2025. Credit: AP Photo/Dirk Heinrich Susan de Meyer’s horses have different effects on different children. Hyperactive kids learn to be a little quieter around them while nonverbal children are moved to communicate…

, 2025-04-21 05:33:00 TOPLINE: The Global Burden of Disease (GBD) Study 2021 reported 44.84 million disability-adjusted life years (DALYs) because of skin and subcutaneous diseases. METHODOLOGY: Researchers utilized data from the GBD Study 2021 to examine incidence, prevalence, and DALYs for 371 diseases and injuries across 204 countries and territories from 1990 to 2021. Skin…

, 2025-04-21 05:13:00 Right after residency, Maryland-based hospitalist Anisha Bassi, MD, took on a 7 days on/7 days off shift. She worked 12-hour days, and if she wanted to boost her income, she would add in an overnight, or a 4 AM to noon. It was tiring, she said, but she was young, and it…

, 2025-04-21 04:10:00 Credit: Pixabay/CC0 Public Domain “Tusi,” also known as “tucibí” or “pink cocaine,” is a drug concoction that emerged in Latin America and Europe within the past decade and is becoming increasingly popular in the U.S. A study published in Addiction estimates that in 2024, 2.7% of electronic dance music nightclub-attending adults in…

, 2025-04-21 02:50:00 TOPLINE: A panel of dermatologists reached a consensus on 23 topical ingredients that they considered useful for seven common skin concerns, with retinoids recommended for five of those conditions. METHODOLOGY: A literature review (1990-2020) identified 318 discrete cosmetic ingredients, which were then evaluated by 17 expert dermatologists who were either program directors…

, 2025-04-20 16:47:00 A deeper understanding of osteosarcoma, the most common primary malignant bone tumor affecting children and adolescents, is reshaping strategies for overcoming treatment resistance. Central to this breakthrough is Nuclear factor E2-related factor 2 (Nrf2), a transcription factor now recognized as a pivotal player in chemoradiotherapy resistance. Traditionally acknowledged for its role in…

, 2025-04-20 17:04:00 Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC). This review article highlights how disruptions in lipid regulation can significantly influence the behavior of breast cancer cells, impacting their growth, metastasis, and response to…

, 2025-04-20 17:19:00 A new review published in Genes & Diseases highlights the transformative role of microRNAs (miRNAs) in regulating and potentially reversing adipose tissue fibrosis, a condition closely linked to obesity, diabetes, and cardiovascular disease. Fibrosis, driven by abnormal extracellular matrix (ECM) accumulation, disrupts normal adipose tissue function and contributes to broader organ dysfunction….

, 2025-04-20 18:49:00 by Jeffrey Lo, MD, Attending Physician, Orthopedics and Sports Medicine Department, Boston Children’s Hospital When a child tumbles to the floor from a blow to the head, a parent’s inner alarms should sound. The child may have a brain injury. Here’s what parents need to know: What is a concussion? A concussion…

, 2025-04-20 17:36:00 Anaplastic thyroid cancer (ATC), a rare yet highly aggressive malignancy, continues to represent a major clinical challenge. A recent review published in Genes & Diseases offers a comprehensive overview of the molecular mechanisms, diagnostic approaches, and therapeutic strategies driving current and future management of this lethal disease. ATC, accounting for a small…

, 2025-04-20 18:51:00 Credit: Pixabay/CC0 Public Domain The head of the hospital service on the French Indian Ocean island of Reunion on Sunday called for medical reinforcements to cope with an epidemic of the mosquito-borne chikungunya disease. “We are really stretched to our limits,” Lionel Calenge told the RMC radio station. “Epidemiologists predicted the epidemic…

, 2025-04-20 17:42:00 A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular mechanisms and therapeutic interventions for achondroplasia, the most common form of genetic dwarfism. This disorder stems primarily from gain-of-function mutations in the fibroblast growth factor receptor 3 (FGFR3) gene, which exerts widespread effects…

, 2025-04-20 17:57:00 Researchers from Tokyo Metropolitan University have found that the motion of unlabeled cells can be used to tell whether they are cancerous or healthy. They observed malignant fibrosarcoma cells and healthy fibroblasts on a dish and found that tracking and analysis of their paths can be used to differentiate them with up…

Frank Vinluan , 2025-04-20 18:05:00 Sanofi and Regeneron Pharmaceuticals drug Dupixent has won FDA approval for chronic spontaneous urticaria, introducing a new approach to the treatment of this inflammatory skin disorder. It’s the seventh FDA approved indication for the blockbuster product. The regulatory decision announced Friday covers the treatment of patients age 12 and older…

, 2025-04-20 17:49:00 In popular culture, dads are stoic, sensitive and strong. So powerful is the mystique of the happy dad that celebrities, joke books – even hard seltzers – carry the label. Real life is different. Fathers get down, sometimes debilitatingly. And as new research from Rutgers Health reveals, when paternal depression goes undiagnosed…

, 2025-04-20 17:32:00 A new wave of scientific interest is spotlighting GOT2—glutamic-oxaloacetic transaminase 2—as a compelling therapeutic target in the fight against pancreatic cancer, one of the most lethal and treatment-resistant malignancies. This mitochondrial enzyme, deeply embedded in glutamine metabolism, plays a central role in sustaining cancer cell survival and growth. By regulating the malate-aspartate…

, 2025-04-20 17:07:00 Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease. This process, driven by the enzyme family known as peptidyl arginine deiminases (PADs), converts the amino acid arginine into citrulline, neutralizing its charge and fundamentally altering protein structure and behavior. Among its most…

, 2025-04-20 16:57:00 In a transformative review, small noncoding RNAs (sncRNAs) have emerged as pivotal regulators in the complex landscape of cardiovascular diseases. These RNA molecules, which do not encode proteins, were long overshadowed by their well-studied counterparts such as microRNAs. However, new insights highlight the substantial biological impact of lesser-known sncRNA subclasses including transfer…

Katie Adams , 2025-04-20 13:44:00 The healthcare industry has faced a flurry of sweeping changes at the federal level since President Donald Trump took office. In recent months, healthcare leaders have scrambled to come up with strategies to address proposed Medicaid cuts, slashed research funding and the dismantling of the country’s public health infrastructure. Now,…

Houda Hachad , 2025-04-20 13:47:00 Genomic medicine leverages an individual’s genetic information to guide healthcare decisions, with drug-gene testing (also known as pharmacogenomics, or PGx) being a key application that personalizes medication needs based on genetics. Although PGx testing offers a more precise, personalized approach to prescribing medications more safely and effectively, benefiting both patients…