, 2025-04-25 12:26:00 TOPLINE: Spleen stiffness measurement (SSM) demonstrated strong predictive accuracy for liver decompensation in patients with compensated advanced chronic liver disease (cACLD), with an optimal cutoff of 50 kPa. METHODOLOGY: Portal hypertension is a key prognostic factor in cACLD. Although hepatic venous pressure gradient measurement is the gold standard for assessing it, noninvasive…
Sara Kellner , 2025-04-25 19:26:00 April 25, 2025 1 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Jonathan Wosen , 2025-04-25 15:36:00 Akeso, a Chinese biotech that made headlines for beating Merck’s Keytruda in a head-to-head trial, won approval in China this week for the therapy, a company spokesperson confirmed to STAT. New data show early hints of the medicine improving patient survival — the gold standard outcome of any cancer study….
, 2025-04-25 16:58:00 by I. Edwards Novavax’s COVID-19 vaccine could soon receive full approval from the U.S. Food and Drug Administration (FDA), the company said Wednesday. The update sent Novavax’s stock up more than 21% in early trading. It also helped ease fears that the decision had been delayed by the Trump Administration, The Associated…
, 2025-04-26 02:12:00 Researchers at University of California San Diego found that cigarette smoking continues to decline across the United States, largely driven by young adults. Their study, published in JAMA Network Open on April 25, 2025, reveals that the states with historically high smoking rates have seen the most dramatic declines. However, smoking cessation…
, 2025-04-25 12:44:00 The National Pharmacy Association (NPA) has stepped back from plans for coordinated action that could have led to high street pharmacies in England limiting their opening hours and cutting services in a dispute over funding. The decision follows a settlement offer from the government, which the NPA described as a “clear step…
Philip Gioia; Nancy Hemphill, ELS, FAAO , 2025-04-26 01:15:00 LOS ANGELES — Nordic Pharma and Harrow partnered to launch an authorized generic of Maxitrol, Nordic President Philip Gioia said in this Healio Video Perspective from SightLine.Gioia said the neomycin and polymyxin B sulfates and dexamethasone ophthalmic suspension will offer a more cost-effective generic option for…
Associated Press , 2025-04-25 18:36:00 NEW YORK — Luigi Mangione pleaded not guilty Friday to a federal murder charge in the killing of UnitedHealthcare CEO Brian Thompson as prosecutors formally declared their intent to seek the death penalty and the judge warned the Justice Department to stop making public comments that could spoil the case. Mangione, 26,…
, 2025-04-25 17:00:00 The U.S. Preventive Services Task Force (USPSTF) recommends counseling for women at increased risk for perinatal depression (PND). This recommendation forms the basis of a draft recommendation statement published online April 22. Researchers from the USPSTF reviewed the benefits and harms of primary care-relevant interventions to prevent PND to update the 2019…
, 2025-04-25 18:46:00 A rare cell type in the lungs is essential to survival from the COVID-19 virus, a new study shows. Experiments in mice infected with the SARS-CoV-2 virus revealed that the immune cell class in question, called nerve and airway-associated interstitial macrophages, or NAMs, may keep the human immune system’s initial counterattack on…
, 2025-04-25 12:54:00 TOPLINE: Children who received multiple antibiotic courses between birth and 2 years of age had a higher risk of developing asthma, food allergies, allergic rhinitis, and intellectual disability, according to a new study. METHODOLOGY: Researchers analyzed data from a large nationally representative population to examine the associations between antibiotic exposure patterns within…
Anthony DeFino , 2025-04-25 22:02:00 April 25, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Tara Bannow , 2025-04-25 21:20:00 Tara Bannow covers hospitals, providers, and insurers. You can reach Tara on Signal at tarabannow.70. Sutter Health has agreed to pay about $230 million to settle a federal class-action lawsuit accusing the Northern California health system of anticompetitive behavior that raised costs for millions of Californians. Both sides agreed to…
, 2025-04-25 17:01:00 Six in 10 women believe they will hit menopause in their 40s, according to survey results released April 8 by The Ohio State University Wexner Medical Center in Columbus. The survey (web and telephone) was conducted in two waves from Feb. 7 to 10, 2025, and Feb. 21 to 24, 2025, with…
, 2025-04-25 18:59:00 Researchers in South Korea have developed an organoid disease model and non-destructive stiffness analysis technology for evaluating the efficacy of new drugs for fatty liver disease. The research team led by Dr. Hyunwoo Kim and Dr. Myungae Bae at the Korea Research Institute of Chemical Technology (KRICT) has developed the nano-probe-based quantitative stiffness…
, 2025-04-25 13:25:00 The National Institute for Health and Care Excellence (NICE) has recommended ribociclib (Kisqali, Novartis) as an adjuvant treatment for early breast cancer in patients at high risk of recurrence. The recommendation applies to patients in England with HR-positive, HER2-negative early breast cancer. This is the most common breast cancer subtype, accounting for…
Luidgi Faubert , 2025-04-25 14:12:00 Health insurance is rapidly evolving, requiring providers and employers to be adaptable. If you have employees, you must consider what they need from their coverage while considering costs. Here’s a guide on 2025 developments in health care benefits. What Are the Major Trends Emerging in Health Care Benefits? Understanding recent…
Andrew (Drew) Rhoades; Lydia Alexander, MD , 2025-04-25 22:31:00 April 25, 2025 6 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . ” data-action=subscribe> Subscribe We were unable to process your request….
Elizabeth Cooney , 2025-04-25 21:43:00 Vasan Ramachandran is baffled. A cardiologist and veteran of the famed Framingham Heart Study, he is struggling to understand why a similar study he brought to life in 10 rural counties across four Southern states is facing elimination. The RURAL Cohort Study, set in motion six years ago, was nearing…
, 2025-04-25 17:03:00 More than one in seven adults reported carrying medical debt in 2023, and of these, one in three forwent mental health care in the subsequent year, according to a research letter published online April 18 in JAMA Health Forum. Kyle J. Moon, from the Johns Hopkins Bloomberg School of Public Health in…
, 2025-04-25 19:11:00 According to the World Health Organization (WHO), over 22% of the global population smokes, with more than 9 million smoking-related deaths reported annually. Effective treatments to alleviate nicotine withdrawal symptoms caused by smoking cessation are essential for successful smoking cessation. Currently, approved treatments for nicotine withdrawal include Bupropion and Varenicline, but there…
, 2025-04-25 14:56:00 The US Food and Drug Administration (FDA) has approved penpulimab-kcqx (Akeso Biopharma) in combination with cisplatin or carboplatin and gemcitabine as first-line treatment for adults with certain types of nasopharyngeal carcinoma (NPC), and as a single agent for certain patients with NPC disease progression on or after other treatments. Specifically, the novel…
Frank Vinluan , 2025-04-25 17:22:00 Caribou Biosciences’ 2025 outlook aimed for key trial readouts for two cancer cell therapies in the first half of the year and the start of clinical testing in an autoimmune disease. The CRISPR biotech is now shelving the autoimmune program and slashing staff in order to focus its resources and…
Michael McHale , 2025-04-25 07:30:00 Development means that Tallaght laboratory ‘future-proofed’ for expected increases in demand The installation of cutting-edge sample testing technology is set to significantly increase a Dublin hospital’s capacity to test patient samples. The Cellular Pathology Laboratory at Tallaght University Hospital (TUH) recently introduced the Axlab AS-410 M, auto slide preparation system….
, 2025-04-25 17:29:00 Indianapolis-based pharmaceutical behemoth Eli Lilly has filed lawsuits against four compounders claiming that they sold unapproved products that contain tirzepatide, a key ingredient in the company’s weight-loss and diabetes drugs, including top-seller Mounjaro. The lawsuits against Mochi Health, Fella Health and Delilah, and Henry Meds were filed in the U.S. District Court Northern…
Moira Mahoney , 2025-04-25 20:21:00 April 25, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Jonathan Wosen , 2025-04-25 19:29:00 The National Institutes of Health on Friday announced six acting directors to run institutes, many to fill vacancies created by the ouster of predecessors as part of the Trump administration’s unprecedented reshaping of federal scientific agencies. In an email from the NIH Executive Secretariat obtained by STAT, the agency said…
, 2025-04-25 18:00:00 Skin-related fibroblasts with nuclei stained green and f-actin stained red. Credit: Jude Phillip, Johns Hopkins University Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also…
, 2025-04-25 19:21:00 It’s no secret that our waistlines often expand in middle-age, but the problem isn’t strictly cosmetic. Belly fat accelerates aging and slows down metabolism, increasing our risk for developing diabetes, heart problems and other chronic diseases. Exactly how age transforms a six pack into a softer stomach, however, is murky. Now preclinical…
, 2025-04-25 15:30:00 The presence of five key proteins in the blood was strongly associated with the development of metabolic dysfunction-associated steatotic liver disease (MASLD) as much as 16 years before symptoms appeared, new research showed. “This represents the first high-performance, ultra-early (16 years) predictive model for MASLD,” said first author Shiyi Yu, MD, resident…
Katie Adams , 2025-04-25 18:06:00 Orchestra BioMed’s hypertension treatment is the latest medical device to earn the FDA’s breakthrough designation. The device is an atrio-ventricular interval modulation therapy, meaning it uses a pacing algorithm to actively lower blood pressure. By granting Orchestra’s product a breakthrough device status, the FDA is putting it on a fast…
Michael McHale , 2025-04-25 07:30:00 Open letter to Government opposes plans to re-examine labelling measures which are due to begin in May 2026 The planned introduction of health information labelling on alcohol should not be ‘derailed or delayed’ by industry lobbying, an open letter signed by more than 75 health advocates has said. The letter…
, 2025-04-25 17:51:00 ECG diagnostics software platform AccurKardia and cardiac medical technology company HeartBeam are joining forces to make AccurKardia’s ECG analysis software available on HeartBeam’s devices. HeartBeam’s cable-free, 12-lead ECG system captures electrical signals from the heart from three directions to assess arrhythmias. The platform is designed for portable devices so physicians can identify…
Mike Dennison , 2025-04-25 18:30:00 Hospitals have spent years amassing political influence at the federal and state levels. According to the nonprofit OpenSecrets, hospitals and nursing homes’ federal lobbying spending rose from $35 million in 2000 to more than $133 million last year, a 280% increase. They recently had a unique opportunity to flex some…
Emma Bascom; Stéphanie J. Madill, PhD , 2025-04-25 16:22:00 April 25, 2025 9 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We…
Ed Silverman , 2025-04-25 15:40:00 Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others. That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is…
, 2025-04-25 17:04:00 Amy Fletcher, Pilot Plant manager, and Reid Waterman, third-year food science major, start the ice cream maker in the pilot food processing facility on the UC Davis campus. Store-bought ice cream usually falls into the “ultra-processed” food category. Credit: Alysha Beck/UC Davis Take a stroll down the middle aisles of any American…
, 2025-04-25 17:26:00 A traditional African diet rich in vegetables, fibre, and fermented foods can reverse inflammation and protect against chronic diseases in just two weeks, while Western diets exacerbate these conditions, researchers say. The research, conducted by scientists from Radboud University Medical Centre, in the Netherlands, and KCMC University, in Tanzania, found that even a short-term…
, 2025-04-25 16:06:00 TOPLINE: In patients with type 2 diabetes (T2D), sodium-glucose cotransporter 2 (SGLT2) inhibitors significantly increase the risk for falls, and combined use with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) further heightened this risk, emphasizing the need for careful management and support for patients receiving these therapies. METHODOLOGY: The increased risk for…
, 2025-04-25 15:03:00 As artificial intelligence (AI) continues to reshape industries, healthcare remains pivotal. While many health systems have attempted to implement AI through point solutions—single-use applications that address specific needs—these fragmented tools often fail to deliver lasting value. The real potential of AI lies in a platform approach, where a unified system can repurpose…
Ganesh Padmanabhan , 2025-04-25 14:20:00 In 2010, the Affordable Care Act redefined access to healthcare. Fifteen years later, we find ourselves facing a different kind of challenge — not who can enter the system, but how the system works once they’re inside. We now spend over $5.1 trillion annually on healthcare — nearly 19% of…
Terence Cosgrave , 2025-04-25 07:30:00 The doctors gathered in Killarney for the IMO AGM do not lack passion, writes Terence Cosgrave Once again this weekend, in Killarney — hometown of George McNeice, where the air smells of rain and redemption, the doctors of Ireland gather. The annual assembly of the Irish Medical Organisation (IMO), an…
Dr Gabrielle McCormick , 2025-04-25 14:00:00 Have you ever worried that a single thing you did without thinking could harm the one you love most? Welcome to pregnant life! With a mom’s gestational health under scrutiny as an explanation for Autism Spectrum Disorder, it’s no surprise then that it’s a source of unease. But what…
, 2025-04-25 14:43:00 Woebot Health, maker of an AI-powered mental health chatbot, sent an email to users announcing it is retiring its app as of June 30. Woebot’s nonprescription digital mental health tool includes content specific to teens, including media literacy, bullying in school settings, and body image and psychoeducation. According to Behavioral Health Business,…
Justin Cooper , 2025-04-25 15:18:00 April 25, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
O. Rose Broderick , 2025-04-25 14:03:00 Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds. Sign up here. STAT’s illustrious biotech podcast, “The Readout LOUD,” published its 350th episode on Thursday! If you’ve never listened, now’s the perfect time to tune in. Alison, Adam and Elaine sing at the…
, 2025-04-25 14:50:00 Credit: Jonathan Borba/Pexels The seasonal timing of when infants receive the new respiratory syncytial virus (RSV) immunization is crucial for ensuring its effectiveness, according to Yale research published in JAMA Network Open. Nirsevimab is a seasonal immunization that targets RSV in infants. As a monoclonal antibody—a protein that can bind to a…
, 2025-04-25 14:10:00 Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to a high risk of bowel cancer, also a greatly increased risk of duodenal cancer. At present, the only treatment available is close endoscopic monitoring with removal of the precursors, known as polyps, although this is also associated with an increased…
, 2025-04-25 13:29:00 MADRID — Recent research on the progression and treatment of psychosis is prompting some experts to ask: Are substance-induced psychosis (SIP) and primary psychosis fundamentally different? And if they are, does it matter? Treatment of first-episode psychosis (FEP) in patients who also use cannabis is often a challenge because it is frequently…
Traci Sweet , 2025-04-25 13:10:00 Substance use disorder (SUD) remains a costly and dangerous public health challenge that affects over 48 million people in the US annually. High relapse rates, typically 40-60%, lead me to believe that we are not winning the war against drugs using traditional treatment methods like cognitive behavioral therapy (CBT) for…