, 2025-04-26 17:10:00 Credit: CC0 Public Domain Frontotemporal dementia has gained significant attention in recent years after the family of actor Bruce Willis announced in 2023 that he had been diagnosed with the condition. A year later, it was revealed that US chat show host Wendy Williams had also been diagnosed with the condition. Yet…
Erik Swain , 2025-04-25 13:49:00 April 25, 2025 4 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . ” data-action=subscribe> Subscribe We were unable to process your request. Please try again later….
, 2025-04-25 16:02:00 Since the 1950s, when researchers first linked smoking to lung cancer, national smoking rates have dropped dramatically. Credit: Matthew Stone/John Pierce, UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science Researchers at University of California San Diego found that cigarette smoking continues to decline across the United States,…
Andrew (Drew) Rhoades; Harold E. Bays, MD, FOMA, FTOS, FACC, FASPC, FNLA , 2025-04-26 15:43:00 April 26, 2025 2 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted…
, 2025-04-25 16:10:00 Adipogenesis contributes to age-related visceral adipose tissue accumulation. Credit: Science (2025). DOI: 10.1126/science.adj0430 It’s no secret that our waistlines often expand in middle age, but the problem isn’t strictly cosmetic. Belly fat accelerates aging and slows down metabolism, increasing our risk for developing diabetes, heart problems and other chronic diseases. Exactly how…
, 2025-04-25 09:59:00 TOPLINE: Surgical treatment of acute cholecystitis in older patients with multiple comorbidities was linked to lower rates of readmissions and emergency department (ED) revisits than nonoperative treatment, challenging the convention that these patients are “too sick” for surgery. METHODOLOGY: Acute cholecystitis in older patients with multiple health issues is linked to a…
Regina Schaffer , 2025-04-25 15:13:00 April 25, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
, 2025-04-25 16:16:00 Habenula input to raphe triggers direct excitation and heterosynaptic inhibition in 5-HT neurons. Credit: Nature Neuroscience (2025). DOI: 10.1038/s41593-025-01912-7 Our lives are filled with binary decisions—choices between one of two alternatives. But what’s really happening inside our brains when we engage in this kind of decision making? A University of Ottawa Faculty…
, 2025-04-25 10:21:00 TOPLINE: Cannabis-related emergency department (ED) visits or hospitalizations increased more than 26-fold over a 13-year period among individuals aged 65 years or older and were associated with a significantly higher risk of dementia than visits for all-cause acute care, a new study showed. METHODOLOGY: This population-based, retrospective, matched cohort study included data…
Michael Monostra , 2025-04-25 15:13:00 April 25, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
, 2025-04-25 16:28:00 Credit: CC0 Public Domain Scientists have identified five specific blood proteins that can accurately predict a person’s risk for developing a serious form of liver disease as early as 16 years before they experience symptoms, enabling early intervention and possible prevention and treatment, according to a study presented at Digestive Disease Week…
, 2025-04-26 02:37:00 Our lives are filled with binary decisions – choices between one of two alternatives. But what’s really happening inside our brains when we engage in this kind of decision making? A University of Ottawa Faculty of Medicine-led study published in Nature Neuroscience sheds new light on these big questions, illuminating a general principle of neural…
, 2025-04-25 10:52:00 The session titled “Defeating Cancer by Curing Infections” at European Society of Clinical Microbiology and Infectious Diseases Global 2025, held in Vienna, Austria, was led by Catharina Alberts, PhD, from the World Health Organization’s International Agency for Research on Cancer, and Francesco Negro, MD, emeritus professor, formerly at the Department of Medicine…
Eamon N. Dreisbach , 2025-04-26 13:30:00 April 26, 2025 1 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to…
, 2025-04-25 16:29:00 In 2019, the screening up-to-date status was 75.9% in Hispanic, 77.2% in Black, 81.8% in white, and 83.0% in Asian members (A). Concordant with increased screening prevalence, CRC incidence rates in these four groups increased from 109.1 to 126.4 cases per 100,000 in 2002 (B), peaked during 2008-2010, consistent with increased early…
, 2025-04-26 02:42:00 As the opioid crisis continues, the number of babies born with neonatal opioid withdrawal syndrome (NOWS) – a condition that affects infants whose mothers used opioids during pregnancy – has risen 5-fold over the past 20 years. According to the Centers for Disease Control (CDC), there are 20,000 infants a year in…
, 2025-04-25 11:03:00 “Do children need photoprotection? Definitely yes,” stated Henry W. Lim, MD, former director of the Department of Dermatology at Henry Ford Health in Detroit, former president of the American Academy of Dermatology, and current president of the International League of Dermatological Societies, during a presentation at The World Congress of Pediatric Dermatology…
Gabrielle M. Grasso , 2025-04-25 15:39:00 April 25, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to…
, 2025-04-25 16:30:00 DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH Researchers using next-generation DNA sequencing have identified four specific genes whose mutations are linked to the development and progression of lethal stomach cancers. This could potentially enable doctors to offer targeted treatments that would spare many patients…
, 2025-04-26 03:04:00 Amyotrophic lateral sclerosis (ALS) is a disease that destroys the nerves necessary for movement. About 30,000 people in the United States are affected, and doctors still don’t know what causes it. To lay the groundwork for better tests, Thomas Jefferson University researchers Phillipe Loher, Eric Londin, PhD, and Isidore Rigoutsos, PhD are…
, 2025-04-25 11:17:00 Overall cancer deaths in the United States continue to decline, but trends are mixed when it comes to deaths associated with specific cancer types and overall cancer incidence, according to the 2025 Annual Report to the Nation on the Status of Cancer. The report — a joint initiative of the National Cancer…
Jennifer Byrne , 2025-04-25 18:00:00 April 25, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Torie Bosch , 2025-04-26 11:00:00 First Opinion is STAT’s platform for interesting, illuminating, and provocative articles about the life sciences writ large, written by biotech insiders, health care workers, researchers, and others. To encourage robust, good-faith discussion about issues raised in First Opinion essays, STAT publishes selected Letters to the Editor received in response to…
, 2025-04-25 16:38:00 Credit: Pixabay/CC0 Public Domain The umbilical cord may become a crystal ball of sorts, helping doctors predict the future of children at risk for long-term health problems, including diabetes, stroke, and liver disease. DNA changes found in cord blood could offer early clues about which infants are at higher risk—opening the door…
, 2025-04-26 04:01:00 Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also helping the immune system to heal wounds. New findings may explain why: Not all senescent skin…
, 2025-04-25 11:33:00 TOPLINE: Advance care planning (ACP) strategies, such as adding ACP coordinators and using the Lightning Report Facilitation, improved patient outcomes in primary care clinics in Nebraska, with an increase noted in the reach of ACP discussions. METHODOLOGY: Researchers conducted a mixed-methods study at two Nebraska primary care sites, focusing on two strategies…
Stephen I. Feller , 2025-04-25 18:01:00 April 25, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to…
Daniel Payne , 2025-04-25 08:30:00 WASHINGTON — After November’s election, many of the lobbyists and lawyers representing the health care industry expected a second Trump term would be much like the first: opportunities for regulatory trims, concerns about budget cuts, and more governing via social media. But less than 100 days into President Trump’s administration,…
, 2025-04-25 16:39:00 Credit: Pixabay/CC0 Public Domain A recent global survey of 156 institutions reveals strong interest in VR-haptic technology for dental training, yet significant barriers impede widespread adoption. The study was led by the University of Eastern Finland and published in Frontiers in Dental Medicine. Combining virtual reality with force feedback, VR-haptic technology is…
, 2025-04-26 04:19:00 The restricted mean survival time (RMST) analysis technique was introduced in health care research about 25 years ago and since then has become widely used in economics, engineering, business and other professions. In clinical settings, RMST is useful because it is a straightforward way to understand the average survival time-the length of…
, 2025-04-25 11:40:00 The October 2024 approval of inavolisib for advanced breast cancer spotlighted a growing problem in breast oncology: Managing the hyperglycemia caused by phosphoinositide 3-kinase (PI3K)/Akt pathway inhibitors. Inavolisib is one of a growing class of inhibitors targeting the PI3K/Akt pathway in certain patients with advanced or metastatic breast cancer. Targeting the pathway,…
Max R. Wursta , 2025-04-25 18:21:00 April 25, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to…
Allison DeAngelis, Jason Mast, and Elaine Chen , 2025-04-25 08:30:00 Allison DeAngelis is the East Coast biotech and venture capital reporter at STAT, reporting where scientific ideas and money meet. She is also co-host of the weekly biotech podcast, The Readout Loud. You can reach Allison on Signal at AllisonDeAngelis.01. Health and Human Services Secretary…
, 2025-04-25 16:45:00 Credit: Pragyan Bezbaruah from Pexels New data published in The Journal of Immunology has revealed the role of Plasmodium falciparum infection (malaria) in the development of Burkitt lymphoma (BL), the most common childhood cancer in equatorial Africa and New Guinea. BL has been associated with P. falciparum malaria since 1958, but the…
, 2025-04-26 04:26:00 BioSkryb Genomics and Tecan Group, today introduced a high-throughput single-cell workflow, combining BioSkryb’s 384-well format of the ResolveOME™ Whole Genome and Transcriptome Single-Cell Core Kit with the Uno Single Cell Dispenser™, provided by Tecan. The integrated solution enables parallel high-resolution analysis of hundreds to thousands of individual cells, addressing growing demand for…
, 2025-04-25 11:41:00 Adjunctive use of xanomeline/trospium chloride (Cobenfy) offered no statistically significant benefit over placebo in adults with symptoms of schizophrenia inadequately controlled by an atypical antipsychotic, according to top-line results from the phase 3 ARISE study. However, adjunctive use of the first-in-class antipsychotic did show a numerical improvement compared with treatment with placebo…
Andrew (Drew) Rhoades; Stephanie C. Viguers; Angela Fitch, MD, FACP, FOMA , 2025-04-25 18:30:00 April 25, 2025 1 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on…
Elaine Chen , 2025-04-25 12:41:00 Novo Nordisk has notched a major legal win against compounding pharmacies that make copies of its diabetes and obesity drug semaglutide, sold under the brand names Ozempic and Wegovy. A federal judge on Thursday ruled against a compounding trade group’s request for a preliminary injunction that would have prevented the…
, 2025-04-25 16:52:00 Microglia (magenta) interacting with T cells (yellow) in the central nervous system of SPG15-deficient mice. Cell nuclei are shown in gray. Credit: Dr. Stumm’s working group/University of Jena Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages…
, 2025-04-26 04:45:00 Background and objectives Traditional Chinese medicine (TCM) is widely used in cancer care in China as an integral part of treatment. This study aimed to understand the motivations of cancer patients in China for adopting TCM in their treatment and to examine their communication with oncologists. Gaining insights into these factors can…
, 2025-04-25 12:00:00 TOPLINE: Depression and loneliness predicted memory decline over time in older adults, while memory decline worsened mood symptoms, according to a new study that highlighted a bidirectional link among these variables. METHODOLOGY: Researchers aimed to study longitudinal relationships among immediate memory, depressive symptomatology, and loneliness, while controlling for age and the number…
Stephen I. Feller , 2025-04-25 18:58:00 April 25, 2025 1 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to…
Ed Silverman , 2025-04-25 13:24:00 And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is still shaping up. We expect to promenade with the official mascots and catch up on our reading, but…
, 2025-04-25 16:54:00 Model of differentiated thyroid cancer (DTC) metastatic progression. Credit: Thyroid® (2025). DOI: 10.1089/thy.2024.0303 Researchers from the Endocrine Tumors group at the Germans Trias i Pujol Research Institute (IGTP), in collaboration with five university hospitals, have conducted the first comprehensive study of DNA methylation patterns in metastatic differentiated thyroid cancer (DTC). Published in…
, 2025-04-26 05:06:00 Researchers from The University of Texas MD Anderson Cancer Center will present promising results from clinical trials in three minisymposia abstracts at the American Association for Cancer Research (AACR) Annual Meeting 2025. Findings include a personalized vaccine combination therapy for colorectal cancer, the use of radiotherapy to avoid the toxicities of systemic…
, 2025-04-25 12:00:00 TOPLINE: Radiofrequency microtenotomy using the Topaz technique led to significant pain reduction, functional improvement, and low complication rates in patients with chronic plantar fasciopathy who were unresponsive to conservative treatments. METHODOLOGY: Researchers conducted a systematic review and meta-analysis of 15 studies involving 1576 patients (mean age, 45-55 years) with chronic plantar fasciopathy…
Nancy Hemphill, ELS, FAAO , 2025-04-25 19:17:00 April 25, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . ” data-action=subscribe> Subscribe We were unable to process your request. Please try…
Ed Silverman , 2025-04-25 15:25:00 Ed Silverman, a senior writer and Pharmalot columnist at STAT, has been covering the pharmaceutical industry for nearly three decades. Amid growing anxiety over tariffs, Vanderbilt University Medical Center has warned its suppliers that any sudden price hikes attributed to the levies will be rejected unless a company can justify…
, 2025-04-25 16:57:00 Credit: AI-generated image Differentiated thyroid cancer patients who receive radioiodine (RAI) treatment after surgery have increased relative survival rates compared to those who do not receive the treatment. According to new research published in the April issue of The Journal of Nuclear Medicine, the clear trend for a higher long-term survival rate…
, 2025-04-26 03:24:00 Even for patients covered by Medicare, annual out-of-pocket costs for lifesaving cancer treatments taken in pill form have often exceeded $10,000-until recently. Thanks to changes in Medicare Part D introduced by the Inflation Reduction Act (IRA) that took effect in 2025, annual out-of-pocket drug costs for all beneficiaries are now capped at…