Elaine Chen , 2025-05-01 13:40:00 Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning. I’m both excited and terrified to report that it’s May! Time flies when we’ve got lots of news. The need-to-know this morning Madrigal Pharmaceuticals reported $137.3 million…
, 2025-05-01 16:37:00 Credit: Marcus Aurelius from Pexels Only 2% of people over the age of 70 strength train at least twice a week. This is worrying, as age-related muscle loss can increase risk of social isolation, falls, loss of independence and even early death. There are many reasons why older people may avoid strength…
, 2025-05-01 02:28:00 New research links high-fructose diets, especially from processed foods, to disrupted appetite signals and long-term brain changes, raising concerns for developing brains. Review: Mindful Eating: A Deep Insight Into Fructose Metabolism and Its Effects on Appetite Regulation and Brain Function. Image Credit: Oleksandra Naumenko / Shutterstock A recent review study published in the Journal…
, 2025-05-01 14:55:00 The European Medicines Agency’s (EMA) committee on human medicines has approved extended indications for two medicines used to treat Hodgkin disease and leukemia, respectively. In Hodgkin disease, Adcetris (brentuximab vedotin, Takeda Pharma A/S) is currently indicated for adult patients with previously untreated CD30+ stage III or IV Hodgkin lymphoma (HL) in combination…
Jack Hooper , 2025-05-01 14:37:00 The ICHRA market isn’t just having a moment — it’s gaining maturity. While new startups and investors are only now waking up to the opportunity, thousands of businesses are already offering flexible, portable health benefits to employees through Individual Coverage Health Reimbursement Arrangements. Forward-thinking employers are turning away from rigid…
Editorial Staff , 2025-05-01 13:34:00 RCPI, Dublin 2 / March 7, 2025 Photos: David Coleman / BobbyStudio The post Photos: RCPI Institute Of Obstetricians & Gynaecologists Spring Conference 2025 appeared first on Irish Medical Times. Source link
, 2025-05-01 14:56:00 Virtual teletherapy company Talkspace is teaming up with online digital safety platform Bark Technologies to offer Talkspace’s mental health offering free of charge to Bark phone and Bark app users. Bark’s content monitoring platform aims to help families recognize potential dangers in children’s online activities. It provides mental health support by connecting…
Sara Kellner , 2025-05-01 14:21:00 Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process your request. Please try again later….
Associated Press , 2025-05-01 14:03:00 President Donald Trump’s administration released a lengthy review of transgender health care on Thursday that advocates for a greater reliance on behavioral therapy rather than broad gender-affirming medical care for youths with gender dysphoria. The 409-page Health and Human Services report questions standards for the treatment of transgender youth issued by…
, 2025-05-01 14:10:00 Schematic illustrating how LIPT1 deficiency impairs the IR-induced, TIP60-ATM–mediated HR damage repair pathway due to a deficiency in α-KG–dependent demethylation. Credit: Science Advances (2025). DOI: 10.1126/sciadv.adt1241 An FDA-designated orphan drug that can target a key vulnerability in lung cancer shows promise in improving the efficacy of radiation treatments in preclinical models, according…
, 2025-05-01 02:29:00 In recent years, there has been a growing trend of an aging patient population and an increasing prevalence of age-associated diseases, underscoring the need for advancing research into the biological mechanisms of aging. Of particular scientific interest are hematopoietic stem cells (HSCs), which undergo profound age-related phenotypic and functional transformations. HSCs, found…
, 2025-05-01 13:41:00 Circulating tumor DNA (ctDNA) saw more success in guiding adjuvant therapy decisions, in a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2025. The phase 2 trial screened for ctDNA in 174 patients with early-stage mismatch repair–deficient solid tumors — 16 types in all, the majority colorectal cancer…
Suhanee Mitragotri, Kevan Shah and Avik Chatterjee , 2025-05-01 13:25:00 Over a million lives have been lost to drug overdoses since the start of the overdose crisis, with opioids accounting for 72% of these deaths. In 2023, the FDA approved naloxone (brand name Narcan) for over-the-counter purchase at pharmacies without a prescription. This marked a…
Hunter Firment , 2025-05-01 13:05:00 Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process your request. Please try again later….
Elaine Chen , 2025-05-01 12:02:00 Shares of Eli Lilly dropped in pre-market trading Thursday, as competitor Novo Nordisk secured a major win on insurance coverage of its obesity drug and as Lilly reported first-quarter earnings that fell short of what investors wanted to see. CVS Caremark, the largest pharmacy benefit manager in the U.S., announced…
, 2025-05-01 12:09:00 Study design observation occurred across a 10–12 weeks competitive cross country season. Credit: European Journal of Sport Science (2025). DOI: 10.1002/ejsc.12261 Collegiate female endurance runners who experience chronic energy deficiency throughout a competitive season may compromise their performance and training benefits, according to a recent study by researchers in the Penn State Department…
, 2025-05-01 02:33:00 Autism spectrum disorder (ASD) is a complex neurodevelopmental condition in which affected individuals experience difficulties in social communication and exhibit restricted, repetitive patterns of behavior or interests. A growing body of research suggests that neurobiological changes, particularly abnormalities in dendritic spines, tiny protrusions on nerve cells where synapses form, may be a…
, 2025-05-01 12:00:00 TOPLINE: An analysis of data from the US Food and Drug Administration Adverse Event Reporting System (FAERS) database revealed differences in patterns of ocular events associated with oral and injectable formulations of semaglutide, with injectable formulations linked to a higher frequency of retinal complications. METHODOLOGY: The FDA has approved semaglutide as both…
Stephanie Baum , 2025-05-01 11:30:00 A new report highlights email as an Achilles’ Heel in healthcare cybersecurity. The Paubox report surveyed 150 healthcare IT leaders and found 63% reported data breaches or security incidents involving email in 2024. The report, 60% of Healthcare Orgs Admit Email Security Failure, highlights what Paubox says is a broken…
Jazmin Orozco Rodriguez , 2025-05-01 09:00:00 Food bank shortages caused by high demand and cuts to federal aid programs have some residents of a small community that straddles Idaho and Nevada growing their own food to get by. For those living in Duck Valley, a reservation of about 1,000 people that is home to the…
Jennifer Byrne , 2025-05-01 11:00:00 Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process your request. Please try again later….
Adam Feuerstein , 2025-05-01 10:30:00 Adam Feuerstein is a senior writer and biotech columnist, reporting on the crossroads of drug development, business, Wall Street, and biotechnology. He is also a co-host of the weekly biotech podcast The Readout Loud and author of the newsletter Adam’s Biotech Scorecard. You can reach Adam on Signal at stataf.54….
, 2025-05-01 09:00:00 Credit: Pixabay/CC0 Public Domain University of Pittsburgh School of Medicine scientists are one step closer to developing a brain-computer interface, or BCI, that allows people with tetraplegia to restore their lost sense of touch. While exploring a digitally represented object through their artificially created sense of touch, users described the warm fur…
, 2025-05-01 02:59:00 Researchers at Karolinska Institutet have identified biomarkers in the blood associated with symptoms of long COVID, particularly severe respiratory disorders. The discovery can pave the way for future diagnosis and treatment. The results are published in the top-ranking scientific journal Nature Immunology. Long COVID, also known as Post COVID, is a condition…
, 2025-04-30 11:41:00 Neoadjuvant treatment with a programmed cell death 1 (PD-1) inhibitor induces clinical complete response and leads to organ preservation in a high proportion of patients with early-stage, mismatch repair–deficient (MMRd) solid tumors — regardless of tumor type, new data from a phase 2 study showed. Six months of treatment with dostarlimab led…
, 2025-04-30 11:41:00 Neoadjuvant treatment with a programmed cell death 1 (PD-1) inhibitor induces clinical complete response and leads to organ preservation in a high proportion of patients with early-stage, mismatch repair–deficient (MMRd) solid tumors — regardless of tumor type, new data from a phase 2 study showed. Six months of treatment with dostarlimab led…
Editorial Staff , 2025-05-01 09:05:00 RCSI, Dublin 2 / February 26, 2025 Photos: Ross Coleman / BobbyStudio The post Photos: Comórtas Díospóireachta RCSI / UCD / TCD 2025 appeared first on Irish Medical Times. Source link
Bernard J. Wolfson and Vanessa G. Sánchez , 2025-05-01 09:00:00 Sumana Reddy, a primary care physician, struggles on thin financial margins to run Acacia Family Medical Group, the small independent practice she founded 27 years ago in Salinas, a predominantly Latino city in an agricultural valley often called “the salad bowl of the world.” Reddy…
Michael Monostra , 2025-04-30 14:01:00 April 30, 2025 4 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Michael A. Yassa , 2025-05-01 08:30:00 The recent news that the NIH will require universities to certify their diversity programs comply with federal civil rights law created understandable anxiety in the academic community. The confusion is partly due to coverage that suggested NIH is terminating support for any universities that operate diversity, equity, and inclusion…
, 2025-05-01 08:41:00 A study in JAMA Network Open, led by experts at Cincinnati Children’s, used MRI brain scans and cognitive testing to confirm a link between maternal high blood pressure and brain anomalies among preterm infants. Credit: Cincinnati Children’s and JAMA Network Open Many women already know that preeclampsia—a dangerous form of high blood…
, 2025-05-01 03:01:00 A new study led by researchers at Hospital for Special Surgery (HSS) suggests that currently available therapies may help control chronic muscle inflammation in Duchenne muscular dystrophy (DMD), a severe condition that leads to muscle weakness and premature death. The study, published in PNAS, identifies new mechanisms that drive chronic muscle inflammation…
, 2025-04-30 12:00:00 TOPLINE: In patients with multiple sclerosis (MS), higher disability scores were associated with lower levels of vitamin B6; however, endurance exercise resulted in an increase in levels of vitamins B6 and B2 in patients with greater disability, a secondary analysis of a new trial showed. METHODOLOGY: A total of 106 individuals with…
Andrew (Drew) Rhoades; Jerry D. McConnell, MD, DABOM, MFOMA , 2025-04-30 14:03:00 April 30, 2025 2 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ …
Helen Branswell , 2025-04-30 08:30:00 It’s been less than three months since Robert F. Kennedy Jr. was sworn in as the U.S. health secretary and already there have been many signs the longtime critic of vaccines intends to use his extensive powers over regulation, policy, and research funding to influence Americans’ thinking about them. There…
, 2025-05-01 06:10:00 A health-related query on Google is displayed on a computer screen in New York on Thursday, April 24, 2025. Credit: AP Photo/Patrick Sison Dr. Google is often on call for worried patients, but it may not give the best advice. Doctors say internet searches for medical information should be done cautiously, especially…
, 2025-05-01 03:23:00 Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer’s, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage primarily affects the brain’s blood vessels. University of Connecticut researchers report in the April 16 issue of Science Advances that mutations in the TARDBP gene that reduce TDP-43 protein levels also…
, 2025-04-30 12:00:00 TOPLINE: More than 90% of patients with inflammatory bowel disease (IBD) accepted the switch from the adalimumab reference product to adalimumab biosimilars, with favourable survival and remission outcomes and a positive patient experience at 12 months. A poor opinion of generic drugs was associated with the refusal to switch. METHODOLOGY: Researchers conducted…
, 2025-05-01 06:05:00 Who has not forgotten a name, occasionally misplaced things, or stumbled over the right word during a conversation? However, with growing awareness about dementia, these occasional memory lapses often leave people wondering if it could be an early sign of dementia. As people get older, you might notice that it takes a…
Justin Cooper , 2025-04-30 14:58:00 April 30, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Katie Palmer , 2025-04-30 08:30:00 Katie Palmer covers telehealth, clinical artificial intelligence, and the health data economy — with an emphasis on the impacts of digital health care for patients, providers, and businesses. You can reach Katie on Signal at palmer.01. It’s been a year since the federal government clarified that technology tools used in…
, 2025-04-30 20:49:00 Credit: CC0 Public Domain Sodium-glucose cotransporter-2 inhibitors (SGLT2i), or gliflozins, are medications used in the treatment of type 2 diabetes mellitus (T2DM). They are designed to lower high blood glucose levels typical in T2DM, and work by inhibiting the sodium-glucose transport protein 2. SGLT2i have also been shown to improve outcomes among…
, 2025-05-01 03:44:00 Difficulty finding words or the habit of substituting them with others that are similar semantically – such as knife and cutter – or phonologically – such as knife and wife – are usually the first symptoms of a type of dementia known as primary progressive aphasia (PPA). Another sign is a subtle…
, 2025-04-30 12:00:00 TOPLINE: Neonates born very preterm receiving 2 hours of immediate skin-to-skin contact (SSC) with their mothers showed no improvement in neurodevelopmental outcomes at 2-3 years of age, according to a Norwegian trial; however, SSC resulted in increased breastfeeding rates at hospital discharge (84% vs 67%; P = .04) and up to the…
Scott Buzby , 2025-04-30 15:00:00 April 30, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Torie Bosch , 2025-04-30 08:30:00 In the 19th century, medical schools were desperate for corpses from which their students could learn. Grave robbers would sell bodies; sometimes, janitors, students, or even instructors would themselves dig up corpses. Today’s medical students don’t have to go into cemeteries themselves, but schools still struggle to find cadavers that…
, 2025-04-30 21:00:00 Credit: Unsplash/CC0 Public Domain Results from the ESSENCE Phase III clinical trial published in the New England Journal of Medicine show treating patients with semaglutide can halt and even reverse liver disease. The placebo-controlled outcome trial of participants with a life-threatening form of liver disease known as metabolic dysfunction associated steatohepatitis (MASH)…
, 2025-05-01 03:57:00 Women who suffer from endometriosis have an increased risk of premature and early menopause, both naturally and surgically, University of Queensland researchers have found. A comprehensive international study found women with endometriosis are at 7 times the risk of surgical menopause (involving the removal of both ovaries) and face a higher risk…
, 2025-04-30 12:01:00 Robert Den, MD, a radiation oncologist in Philadelphia, constantly reminds himself that while he’s in the ‘cancer world’ every minute of the day, his patients aren’t. “As oncologists, we may be meeting with the third patient that day with a newly diagnosed metastatic cancer, but for this individual, this is their first…
Michela Cimberle , 2025-04-30 18:30:00 April 30, 2025 13 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . ” data-action=subscribe> Subscribe We were unable to process your request. Please try again later….