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FDA Approves Novel Treatment for KRAS-Mutated Ovarian Cancer

, 2025-05-08 20:02:00 The US Food and Drug Administration (FDA) has granted accelerated approval of combination avutometinib and defactinib (Avmapki Fakzynja Co-pack, Verastem, Inc.) for the treatment of certain patients with KRAS-mutated recurrent low-grade serous ovarian cancer (LGSOC). Specifically, approval is for adults who received at least one prior systemic therapy, including a platinum-based regimen,…

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Accelerated FDA Approval Makes Verastem Drug the First Therapy for Rare Type of Ovarian Cancer

Frank Vinluan , 2025-05-08 20:43:00 A rare type of ovarian cancer that grows slowly and responds poorly to chemotherapy now has its first FDA-approved treatment, a combination drug developed by Verastem Oncology to address a pathway that drives tumor progression. The approval announced Thursday covers the treatment of low-grade serous ovarian cancer (LGSOC) driven by…

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Cutting Medicaid Is Hard — Even for the GOP

, 2025-05-08 19:25:00 The Host Julie Rovner KFF Health News @jrovner @julierovner.bsky.social Read Julie’s stories. Julie Rovner is chief Washington correspondent and host of KFF Health News’ weekly health policy news podcast, “What the Health?” A noted expert on health policy issues, Julie is the author of the critically praised reference book “Health Care Politics…

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Suicidality is more prevalent among adolescents exposed to adverse childhood experiences, research finds

, 2025-05-08 19:43:00 Credit: Huy Phan from Pexels A recent doctoral dissertation reveals that adverse childhood experiences, such as abuse and neglect, predispose adolescents to suicidality. Girls had a higher risk of a suicidal event occurring during treatment, and suicidality risk screening at intake to behavioral and mental health services failed to predict a large…

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Medical Gaslighting Common in Vulvovaginal Care

, 2025-05-08 15:05:00 TOPLINE: In a cross-sectional study of 447 patients with vulvovaginal disorders, 52.8% considered ceasing care due to unaddressed concerns, while 39.4% reported being made to feel ‘crazy’ — rated as the most distressing behavior with a mean distress score of 7.39 out of 10. Patients reported that only 43.5% of past practitioners…

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Sonde Health partners with Saaya Health for blue collar care

, 2025-05-08 15:54:00 AI-enabled voice technology platform Sonde Health announced it is partnering with Saaya Health, a virtual mental health and well-being platform, to extend its combined offerings to large blue-collar workforces. Sonde Health’s platform uses its patented voice technology that analyzes short voice samples to detect various health conditions from biomarkers in a person’s…

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Sen. Ron Wyden Seeks Answers on RFK Jr.’s Purge of FOIA Staff

Rachana Pradhan , 2025-05-08 16:27:00 Rachana Pradhan The Department of Health and Human Services’ mass dismissals of workers who release government records “raise grave transparency, accountability, and privacy concerns,” Oregon Sen. Ron Wyden said Thursday. In a May 8 letter to HHS Secretary Robert F. Kennedy Jr. provided exclusively to KFF Health News, Wyden, the…

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Europe Unites Against Alcohol Harm

, 2025-05-08 15:30:00 AMSTERDAM — Today, the EU launched a new coalition of health organizations and experts to advocate for the reduction of alcohol-related illnesses, injuries, and deaths here at the European Association for the Study of the Liver (EASL) Congress 2025. The European Health Alliance on Alcohol aims to reduce alcohol’s impact on health,…

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Chipiron raises $17M for miniature MRI prototype

, 2025-05-08 15:59:00 Chipiron, a deeptech startup that specializes in ultra-low MRI, announced it raised $17 million in  Series A funding round led by Blast.  EIC Fund and iXcore participated in the round with support from France2030 (SGI), the EIC Accelerator (European Commission) and Bpifrance. WHAT IT DOES  The company aims to “democratize” access to…

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Study uncovers how co-infection by two bacteria suppresses immune response

, 2025-05-08 14:01:00 The incidence of infection by Mycobacterium abscessus, is increasing in patients with cystic fibrosis, chronic obstructive pulmonary disease (COPD), and other chronic pulmonary diseases, leading to an accelerated lung function decline. Remarkably, 58–78% of patients with M. abscessus infection are also infected with Pseudomonas aeruginosa, the most common pathogen in these conditions….

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MHRA Approves First UK Treatment for Thyroid Eye Disease

, 2025-05-08 14:20:00 The Medicines and Healthcare products Regulatory Agency (MHRA) has approved teprotumumab (Tepezza, Amgen) as the first treatment to be licensed in the UK for adults with moderate to severe thyroid eye disease. Thyroid eye disease, also known as Graves’ orbitopathy, affects up to 40% of individuals with this form of hyperthyroidism. Symptoms…

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Healthcare Marketing is Missing the Mark in Three Big Ways

Meg Dietzel , 2025-05-08 13:48:00 Innovative marketing practices are the goal of every marketer; however, sometimes, it’s essential to consider not what new marketing tactic will be influential but how you can leverage existing marketing practices to solve larger business challenges. Within the healthcare space, marketing can now be used for much more than increasing…

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Is this the real reason diets fail?

Mathuln Piraba , 2025-05-08 14:00:00 ‘Diets don’t work.’ You’ve probably heard this claim many times, and for most people, statistics say it’s true. The question is, why do diets fail? Is it because they are badly thought out? Or, are we just misunderstanding how to follow them? Food scientists at William and Mary University, VA,…

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FDA’s Vinay Prasad, Eli Lilly, autism study

Elaine Chen , 2025-05-08 13:35:00 Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning, we’ve got more news today about Vinay Prasad — let’s get into it. Vinay Prasad makes his debut at FDA One day after he was named the…

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Insulin resistance in youth may inform type 2 diabetes prevention

, 2025-05-08 13:24:00 Credit: Pixabay/CC0 Public Domain Researchers have identified a mechanism underlying insulin resistance in adolescents with obesity. The findings, published in Journal of Clinical Investigation, present a targetable pathway that could one day allow clinicians to intervene and prevent the onset of type 2 diabetes. The number of youths with obesity has skyrocketed…

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Salmonella Outbreak Under Investigation

, 2025-05-08 12:32:00 The US Centers for Disease Control and Prevention (CDC) is investigating a Salmonella outbreak that had infected seven individuals across six states as of April 24, 2025.  According to the CDC website’s information on the investigation, the first case of Salmonella Mbandaka in the current outbreak was reported on February 9, 2025, and…

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what are peptides, long covid, CDC fellowships

Theresa Gaffney , 2025-05-08 11:59:00 Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds. Sign up here. Good morning! We got some personnel news from the Trump administration yesterday: The White House withdrew the nomination of Janette Nesheiwat for U.S. surgeon general. The new name came shortly after: Casey…

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Eating ultra-processed foods may harm your health, research indicates

, 2025-05-08 10:26:00 Credit: Unsplash/CC0 Public Domain Consumption of ultra-processed foods, such as sugar-sweetened beverages, potato chips and packaged cookies, may be associated with adverse health outcomes, according to research being presented at the ACC Asia 2025 Together with SCS 36th Annual Scientific Meeting taking place May 9–11 in Singapore. This risk for hypertension, other…

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How to cut Medicaid costs without hurting care

Sanjay Basu , 2025-05-08 08:30:00 As a primary care physician serving Medicaid patients, I recently witnessed a preventable hospitalization that perfectly illustrates America’s health care dysfunction. My homebound patient with heart failure needed a routine lab test to adjust their medication. While commercially insured patients can access electronic lab orders, my patient’s Medicaid plan contracted…

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Study traces sharp regional shifts in ischemic heart disease burden—a global warning signal

, 2025-05-08 10:20:00 Credit: AI-generated image A new study puts the spotlight on the rising burden of ischemic heart disease across Southeast Asia, East Asia and Oceania, and calls for localized, equity-focused interventions in these regions. The researchers identified region-specific, modifiable risk factors that influence the increasing prevalence of ischemic heart disease, such as toxic…

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Next-generation “armored” CAR T cell therapy shows promising results in lymphoma patients

, 2025-05-08 05:29:00 A next-generation “armored” CAR T cell therapy showed promising results in a small study of patients whose B-cell lymphomas continued to resist multiple rounds of other cancer treatments, including commercially available CAR T cell therapies. The new therapy diminished cancer in 81 percent of patients and resulted in complete remission in 52…

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FAQs About Orthopedics Specialty

, 2025-05-08 09:18:00 Orthopedic specialists can be generally grouped into one of two categories: Surgical and nonsurgical. Within those categories, there are several subspecialties. Orthopedic surgeons may specialize in surgery of the hand, foot and ankle, shoulder and elbow, spine, or in other areas, such as hip and knee replacement. Their training includes a 5-year…

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Inside the peptide craze: Hype, science, and risk

Alex Hogan , 2025-05-08 08:30:00 A constellation of social media wellness influencers, YouTubers, and podcasters have been extolling the health benefits of peptides. There seems to be a peptide for just about anything you could dream of. Want to lose weight? There are GLP-1s, of course. Would you like to have a year-round tan? You…

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Frail Medicare Patients Face Primary Care Follow-Up Gaps

, 2025-05-08 08:09:00 TOPLINE: Vulnerable Medicare beneficiaries with frailty and those needing short-term skilled nursing facility care post-hospitalization were less likely to receive timely primary care follow-up after returning home. METHODOLOGY: Researchers conducted a retrospective cohort study using claims data from Medicare beneficiaries, including 94,248,326 hospital discharges (80.1% aged ≥ 65 years; 55.1% women) between…

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