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Precision nano therapy targets tumor nerves in pancreatic cancer

, 2025-05-09 02:37:00 Announcing a new publication for Acta Materia Medica journal. A preclinical study has developed a precision nano-intervention strategy targeting tumor-associated nerves to destroy nerve-fueled tumor growth in pancreatic cancer. In this strategy, Escherichia coli Nissle 1917-derived outer membrane vesicles (OMVs) are decorated with nerve-binding peptide for targeted delivery of co-loaded tropomyosin receptor…

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Finasteride Linked to Suicidal Ideation

, 2025-05-09 09:38:00 The European Medicines Agency (EMA) has confirmed that suicidal ideation is a potential side effect of finasteride and urged healthcare professionals to advise patients to stop treatment and seek medical advice if they experience depressed mood, depression, or suicidal thoughts. The advice follows an EU-wide review launched in February of available data…

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A new era for patient safety: mandatory open disclosure

Contributor , 2025-05-09 07:30:00 Janet Keane is a Director in DWF’s Healthcare Team based in Dublin, and is a highly experienced and specialist Clinical Negligence Solicitor, having amassed over 15 years’ experience, primarily in the Medical Defence industry, representing GPs, Consultants, and Private Hospitals A landmark shift in Irish healthcare has arrived with the commencement…

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A California Lawmaker Leans Into Her Medical Training in Fight for Health Safety Net

Christine Mai-Duc , 2025-05-09 09:00:00 SACRAMENTO, Calif. — State Sen. Akilah Weber Pierson anticipates that California’s sprawling Medicaid program, known as Medi-Cal, may need to be dialed back after Gov. Gavin Newsom releases his latest budget, which could reflect a multibillion-dollar deficit. Even so, the physician-turned-lawmaker, who was elected to the state Senate in November,…

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As Trump attacks on Harvard intensify, researchers scramble

Brooke Hauser — Boston Globe , 2025-05-09 08:30:00 What would Harvard University be without the money the federal government has provided over decades to underwrite its vast research initiatives? That’s the existential, $9 billion question facing the Harvard community after the Trump administration’s most recent threat in its confrontation with the university: Harvard will not…

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Health care workers, firefighters have increased PFAS levels, study finds

, 2025-05-09 08:29:00 Credit: Pixabay from Pexels A study including researchers from the University of Arizona Health Sciences and published in the Journal of Exposure Science & Environmental Epidemiology found that firefighters had higher concentrations of certain per- and polyfluoroalkyl substances, or PFAS, and health care workers had moderate elevations of PFAS in their blood…

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Why your baby’s first steps may be written in their DNA

, 2025-05-09 02:41:00 A landmark study shows that when babies start walking isn’t just developmental, it’s in their DNA. Genetic variants not only shape motor timing but also link to cognitive traits and brain structure. Thresholding t-statistic image at t > 0.95 (two-sided statistical test). Significant voxels were overlaid on the 40-week neonatal brain template in sagittal, coronal and…

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No Benefit to ERCP With Sphincterotomy in Pancreas Divisum

, 2025-05-09 07:40:00 SAN DIEGO — In treating pancreas divisum, the common use of endoscopic retrograde cholangiopancreatography (ERCP) with minor papilla endoscopic sphincterotomy showed no significant benefit over a sham procedure, suggesting that patients can be spared the intervention, which can carry risks of its own. “This is a topic that has been debated for…

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Longevity Shot? Single Jab May Extend Lifespan By 16 Years

, 2025-05-09 06:59:00 Scientists around the world are racing to unlock the secrets of longer, healthier lives. From promoting exercise and sleep to exploring longevity-boosting diets, they have identified a range of strategies that could help slow the aging process. Now, a groundbreaking new study in mice suggests that the key to extending lifespan might…

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 Early-onset cancer: the types that are on the rise

Associated Press , 2025-05-08 14:16:00 Cancer before age 50 is rare, but increasing, in the United States and researchers want to know why. A new government study provides the most complete picture yet of early-onset cancers, finding that the largest increases are in breast, colorectal, kidney and uterine cancers. Scientists from the National Cancer Institute looked…

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PFAS influence cellular immune response to coronavirus, research finds

, 2025-05-08 20:19:00 Graphical abstract. Credit: Environment International (2025). DOI: 10.1016/j.envint.2025.109409 PFAS are found in multiple everyday products, such as cosmetics, outdoor clothing and coated pans. This is because of their special properties. They are heat-resistant and repel water and grease. There are thousands of different PFAS compounds and they are found in the soil,…

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Study reveals regional risk factors driving heart disease in Asia and Oceania

, 2025-05-09 02:41:00 A new study puts the spotlight on the rising burden of ischemic heart disease across Southeast Asia, East Asia and Oceania, and calls for localized, equity-focused interventions in these regions. The researchers identified region-specific, modifiable risk factors that influence the increasing prevalence of ischemic heart disease, such as toxic air pollution in…

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Why RFK Jr.’s data plans might hit a real world snag

Mario Aguilar , 2025-05-08 15:13:00 You’re reading the web edition of STAT’s Health Tech newsletter, our guide to how technology is transforming the life sciences. Sign up to get it delivered in your inbox every Tuesday and Thursday. Federal health department leaders have touted the potential of using patient data, including health records, to study autism, chronic disease,…

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Biological age can predict cardiovascular disease morbidity and mortality

, 2025-05-08 20:21:00 Credit: Aphiwat chuangchoem from Pexels Looking at your biological age—how old your body really is—can give a clearer picture of your heart disease risk than traditional tools alone. This finding comes from a newly published multicenter study conducted in collaboration between the Universities of Jyväskylä, Tampere, and Helsinki, the Finnish Institute for…

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Hyperlactataemia Tied to Poor Mortality in Patients With AKI

, 2025-05-08 12:00:00 TOPLINE: Serum lactate levels of more than 4 mmol/L on admission to the intensive care unit (ICU) were associated with an increased rate of 60-day mortality in patients with acute kidney injury (AKI) receiving renal replacement therapy (RRT). METHODOLOGY: Researchers conducted a retrospective study over a 4-year period to examine the effect of…

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Standardized criteria for amino acid PET imaging could improve diagnosis and treatment of brain metastases

, 2025-05-08 20:30:00 PET imaging may overcome limitations of MRI. Images show an illustrative example in which amino acid PET reveals early metabolic response to treatment with an antibody–drug conjugate (ADC), while conventional MRI findings remain stable. Credit: Nature Medicine (2025). DOI: 10.1038/s41591-025-03633-7 Brain metastases often occur as a result of advanced cancer, and despite…

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Most of today’s children could endure historic heatwaves as planet warms

, 2025-05-09 03:28:00 New modeling shows that without urgent emissions cuts, most children born today will live through climate extremes far beyond anything seen in human history, with the poorest hit hardest. Study: Global emergence of unprecedented lifetime exposure to climate extremes. Image Credit: Piyaset / Shutterstock In a recent article published in the journal Nature, researchers…

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Blood Ketone Test Tops Urine Test in Gestational Diabetes

, 2025-05-08 12:00:00 TOPLINE: Testing blood ketone levels before breakfast, lunch, and dinner identified a greater number of ketosis episodes than testing urinary ketone levels in women with gestational diabetes (GD). The presence of fasting blood ketones was strongly correlated with the presence of ketones before lunch and dinner, indicating the necessity for more comprehensive…

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Firefighters and health care workers show elevated PFAS levels in new study

, 2025-05-09 02:20:00 A study including researchers from the University of Arizona Health Sciences and published in the Journal of Exposure Science & Environmental Epidemiology found that firefighters had higher concentrations of certain per- and polyfluoroalkyl substances, or PFAS, and health care workers had moderate elevations of PFAS in their blood with significantly higher odds of two specific PFAS…

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UK Study Maps Solar Urticaria Features and Treatments

, 2025-05-08 12:00:00 TOPLINE: In a multicentre cross-sectional study, the majority of patients with solar urticaria were of European ethnicity, with Fitzpatrick skin phototypes I-III; urticaria provocation was achieved using monochromator phototesting in 94.2% of participants, and omalizumab showed the highest complete response rate at 37.5%. METHODOLOGY: Researchers conducted a cross-sectional study at six tertiary…

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Cutting Medicaid is hard — even for the GOP

, 2025-05-09 00:48:00 The host Julie Rovner KFF Health News @jrovner Julie Rovner is chief Washington correspondent and host of KFF Health News’ weekly health policy news podcast, “What the Health?” A noted expert on health policy issues, Julie is the author of the critically praised reference book “Health Care Politics and Policy A to…

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New Pacemaker Smaller Than a Grain of Rice

, 2025-05-08 13:25:00 The future of cardiac pacing may boil down to a single grain of rice. Engineers at Northwestern University in Chicago have developed a biodegradable pacing device so small it can be injected by needle into the heart muscle of newborn babies. The design of the tiny gadget, designed for temporary use and…

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MAGA Calls to ‘Revoke’ Trump’s Surgeon General Nomination Accusing Her of Getting ‘the Covid Jab’: ‘Another MAHA Grifter’

, 2025-05-08 23:20:00 President Donald Trump’s newly announced nominee for US Surgeon General, Dr. Casey Means, is facing backlash from within the MAGA movement after right-wing activist Laura Loomer accused her of being a “MAHA grifter” for previously receiving the COVID-19 vaccine. Loomer shared a screen recording allegedly documenting Means — then using the handle…

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Withings, Babyscripts Team Up to Tackle Hypertensive Disorders of Pregnancy

Marissa Plescia , 2025-05-08 20:41:00 Withings Health Solutions and Babyscripts announced a partnership Thursday that aims to address hypertensive disorders of pregnancy, which are among the leading causes of maternal mortality. This includes preeclampsia, which is high blood pressure that develops during pregnancy or after. Washington, D.C.-based Babyscripts offers a virtual maternity care program that…

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Lab-on-a-chip devices offer home tests for stress and cardiac issues

, 2025-05-08 21:00:00 Saliva samples are inserted into a reader that transmits cortisol measurements to a smart phone. Credit: Andrew Higley University of Cincinnati engineers have created a new device to help doctors diagnose depression and anxiety. UC College of Engineering and Applied Science Distinguished Research Professor Chong Ahn and his students developed a “lab-on-a-chip”…

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FDA Approves Novel Treatment for KRAS-Mutated Ovarian Cancer

, 2025-05-08 20:02:00 The US Food and Drug Administration (FDA) has granted accelerated approval of combination avutometinib and defactinib (Avmapki Fakzynja Co-pack, Verastem, Inc.) for the treatment of certain patients with KRAS-mutated recurrent low-grade serous ovarian cancer (LGSOC). Specifically, approval is for adults who received at least one prior systemic therapy, including a platinum-based regimen,…

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Accelerated FDA Approval Makes Verastem Drug the First Therapy for Rare Type of Ovarian Cancer

Frank Vinluan , 2025-05-08 20:43:00 A rare type of ovarian cancer that grows slowly and responds poorly to chemotherapy now has its first FDA-approved treatment, a combination drug developed by Verastem Oncology to address a pathway that drives tumor progression. The approval announced Thursday covers the treatment of low-grade serous ovarian cancer (LGSOC) driven by…

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