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Why are UK cardiovascular deaths in under 65s rising again?

Sophie Borland , 2025-05-19 08:41:00 Sophie Borland Hertfordshire After more than 20 years of steady decline, cardiovascular deaths in working age adults are increasing. Sophie Borland looks at what’s causing this trend and how to reverse it Just a decade ago newspaper headlines and The BMJ were reporting a dramatic reduction in deaths from heart…

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New High-Risk TNBC Subgroup Identified

, 2025-05-19 09:10:00 New data support integrating tumor-infiltrating lymphocyte levels with nodal status to improve risk stratification in women with triple-negative breast cancer (TNBC) and pathological complete response (pCR) following neoadjuvant treatment. Specifically, patients with lower levels of tumor-infiltrating lymphocytes had a higher risk for relapse and worse overall survival than those with higher levels,…

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Housing, Nutrition in Peril as Trump Pulls Back Medicaid Social Services

Angela Hart , 2025-05-19 09:00:00 During his first administration, President Donald Trump’s top health officials gave North Carolina permission to use Medicaid money for social services not traditionally covered by health insurance. It was a first-in-the-nation experiment to funnel health care money into housing, nutrition, and other social services. Some poor and disabled Medicaid patients…

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Animal models in pharma have become obsolete

Ellen P. Carlin and Jason Paragas , 2025-05-19 08:30:00 The Food and Drug Administration’s recent decision to phase out animal use in preclinical testing of monoclonal antibodies — and eventually other drugs —with more advanced, human-relevant methods marks a transformative shift with profound implications for drug development. The FDA has now officially recognized that advancing…

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Animal models in medical research are more important than ever

Carole LaBonne , 2025-05-19 08:30:00 Imagine a world without lifesaving medicines, preventive care, or therapies — no insulin for diabetes, no vaccines for polio, and fewer (if any) options for treating cancer. What do these amazing medical achievements have in common? They all depended heavily on research using animals, the behind-the-scenes heroes of medical breakthroughs….

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How to Handle Noncompliant Patients on GLP-1 RAs for Obesity

, 2025-05-19 07:10:00 Primary care practices are seeing an uptick in patients inquiring about glucagon-like peptide 1 receptor agonist (GLP-1 RA) medications due to both media hype and sizzle-reel stories they see on social media. If your patients start an appointment with their own agenda about wanting a prescription for these medications, there are ways…

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Screening Teens, Clinicians Discover a Tampon Access Crisis

, 2025-05-19 06:13:00 Asking teenage girls about their access to menstruation products can help pediatricians gain a better understanding of the resources their patients need, whether it be more education or pads and tampons, according to a new study published in Pediatrics. An academic pediatric clinic in North Carolina implemented a three-question screener inquiring if…

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Karger Publishers releases free-access eBook “Healthy Aging”

, 2025-05-19 05:04:00 Designed for doctors and health enthusiasts, “Healthy Aging” contains surprising scientific discoveries and practical guidance on nutrition, healthy sleep, maintaining a social network and physical fitness to contribute to longevity. “Healthy Aging”, Illustrating the importance of proteins in various functions. Image Credit: S. Karger AG The newly released eBook Healthy Aging simplifies the complex…

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USPSTF urges universal syphilis screening in pregnancy to prevent congenital infections

, 2025-05-19 02:31:00 With congenital syphilis at a 30-year high in the US, experts stress that early and universal syphilis screening in pregnancy is vital to protect both mothers and newborns from preventable harm. Study: Screening for Syphilis Infection During Pregnancy: US Preventive Services Task Force Reaffirmation Recommendation Statement. Image Credit: Summit Art Creations / Shutterstock.com…

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Repeated antibiotics in preterm infants linked to long-term lung problems

, 2025-05-19 03:13:00 A major German study finds that early repeated antibiotic use in very low-birth-weight infants can have lasting effects on lung health, highlighting the importance of antibiotic stewardship and preventive care for preterm children. Study: Perinatal Antibiotic Exposure and Respiratory Outcomes in Children Born Preterm. Image Credit: mi_viri / Shutterstock In a recent study published…

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Methotrexate found to be effective alternative to prednisone for pulmonary sarcoidosis

, 2025-05-19 02:45:00 Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects. Now new research published at the ATS 2025 International Conference finds that methotrexate provides a comparable alternative. Researchers found that methotrexate was as effective in controlling the disease, with potentially fewer side…

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Telstra Health onboards Salesforce, Snowflake and more briefs

, 2025-05-19 02:29:00 Telstra Health taps Salesforce, Snowflake for its ongoing modernisation Cloud software providers Salesforce and Snowflake will integrate their solutions into Telstra Health’s upcoming digital health platform. Based on a media release, Snowflake will provide a common data and analytics layer that consolidates disparate datasets across Telstra Health products and services. The resulting…

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Are US girls sacrificing health to slim down?

, 2025-05-19 02:17:00 Despite national guidelines, most American teen girls chase weight loss, often at the expense of healthier habits. New research shows that intent to slim down doesn’t always align with health, underscoring the urgent need for supportive interventions. Study: Lifestyle Behaviors Associated with Weight Loss Intent in Adolescent Girls: Findings from the US…

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Electromagnetic waves disrupt SARS-CoV-2 spike protein and lower infectivity

, 2025-05-19 01:18:00 A new study reveals how targeted electromagnetic waves can disrupt the SARS-CoV-2 spike protein, potentially opening doors to innovative disinfection and infection control strategies. ​​​​​​​Study: Electromagnetic waves destabilize the SARS-CoV-2 Spike protein and reduce SARS-CoV-2 Virus-Like particle (SC2-VLP) infectivity. ​​​​​​​Image Credit: Design_Cells / Shutterstock Electromagnetic waves appear to alter the conformation of the Severe…

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Preference for sweetness drives snack choices and diet quality, study reveals

, 2025-05-19 00:52:00 Study: Sweet taste preference on snack choice, added sugars intake, and diet quality– a pilot study. Image Credit: Mesve79 / Shutterstock.com A recent study published in the journal BMC Nutrition explores how sweetness preference and eating behaviors interact with diet quality and added sugar intake. Sweet preferences, eating behaviors, and the complex path to…

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Former President Joe Biden diagnosed with prostate cancer

Associated Press , 2025-05-18 20:56:00 WASHINGTON — Former President Joe Biden has been diagnosed with prostate cancer, his office said Sunday. Biden was seen last week by doctors after urinary symptoms and a prostate nodule was found. He was diagnosed with prostate cancer on Friday, with the cancer cells having spread to the bone. “While…

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Noninvasive prenatal testing identifies twice as many Down syndrome cases as second-trimester serum screening

, 2025-05-18 18:30:00 Credit: BGI Genomics A novel study has analyzed the cost-effectiveness of different Down syndrome (DS) screening strategies. The result confirms that noninvasive prenatal testing (NIPT) outperforms second-trimester serum screening (STSS) in accuracy and cost-effectiveness, as NIPT identifies twice as many DS cases as STSS. The study was conducted by researchers from Changsha…

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Large-scale analysis reveals distinct genetic patterns in veterans with metastatic prostate cancer

, 2025-05-18 17:19:00 Credit: Pixabay/CC0 Public Domain In the largest clinical genomic profiling study of non-Hispanic Black men with metastatic prostate cancer to date, researchers from Moffitt Cancer Center, University of Pennsylvania, University of California Los Angeles and the Veterans Affairs (VA) National Precision Oncology Program found key differences in tumor biology between non-Hispanic Black…

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Waitlist deaths drop under new lung transplant allocation system

, 2025-05-18 16:20:00 Credit: Pixabay/CC0 Public Domain Two years ago, the United Network for Organ Sharing implemented new allocation guidelines for lung transplants that prioritize medical urgency. Now new research, published at the 2025 ATS International Conference and in the American Journal of Respiratory and Critical Care Medicine, shows that waitlist outcomes significantly improved under…

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Methotrexate as effective as prednisone in pulmonary sarcoidosis, research finds

, 2025-05-18 16:20:00 Credit: Pixabay/CC0 Public Domain Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects. Now new research, published at the ATS 2025 International Conference and in the American Journal of Respiratory and Critical Care Medicine, finds that methotrexate provides a comparable alternative….

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Wearable sensor could be used to monitor obstructive sleep apnea treatment response

, 2025-05-18 16:20:00 System overview. Credit: American Journal of Respiratory and Critical Care Medicine (2025). DOI: 10.1164/ajrccm.2025.211.Abstracts.A1059 A wearable pulse oximeter and connected software platform show promise for monitoring obstructive sleep apnea (OSA) and other sleep-related breathing diseases, according to research presented at the ATS 2025 International Conference. The findings were also published in the…

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Why WeightWatchers Filed for Bankruptcy

Marissa Plescia , 2025-05-18 14:43:00 WeightWatchers has long been a household name, boosted by celebrity endorsements from Oprah Winfrey and Jennifer Hudson. Jean Nidetch founded the New York City company in her apartment in the early 1960s, and grew it to serve more than 4 million members worldwide. From those humble roots, the company evolved…

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Glial cells may play key role in managing sleep and metabolism, fruit fly study suggests

, 2025-05-18 13:40:00 Behavior in freely moving flies and long-term calcium imaging in EG during behavior. Credit: Nature Neuroscience (2025). DOI: 10.1038/s41593-025-01942-1 Homeostasis is the ability of living organisms to maintain stable internal conditions, such as temperature, hydration and blood sugar levels, irrespective of any changes in their surroundings. Homeostatic mechanisms also regulate behaviors that…

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Clinical Trials Have a Research Site Demand and Supply Crisis. Here is How to Solve it

Bree Burks , 2025-05-18 13:45:00 Clinical research sites face an information challenge that hinders efficiency and collaboration. As trial complexity increases, the multiple logins, devices, and spreadsheets site staff use to execute studies create siloed workstreams. In addition, each sponsor has its preferred software solutions for every trial, making collecting, accessing, and sharing data a…

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High times for German cannabis firm amid medical boom

, 2025-05-18 10:05:00 Medical cannabis has been a boon for the Berlin-based company whose website slogan says ‘we love cannabis’ and whose Frankfurt Stock Exchange ticker symbol is ‘HIGH’ At an undisclosed site in Germany’s Bavaria state, pharmaceutical CEO Philip Schetter opens a 75-centimeter (30-inch) thick steel door that secures his wares: vast amounts of…

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Matching mindfulness methods to anxiety symptoms may boost mental well-being, study finds

, 2025-05-18 10:12:00 Credit: Kelvin Valerio from Pexels If you’re anxious about work, finances, the state of the world, or anything else, you might try a moment of mindfulness. Paying close attention to the present moment without judgment—the basic idea behind all mindfulness techniques—can help calm anxiety and improve focus, said Resh Gupta, a postdoctoral…

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FDA approves Novavax Covid vaccine after delay

Helen Branswell , 2025-05-18 00:12:00 Helen Branswell covers issues broadly related to infectious diseases, including outbreaks, preparedness, research, and vaccine development. Follow her on Mastodon and Bluesky. You can reach Helen on Signal at hbranswell.01. The Food and Drug Administration has finally approved Novavax’s Covid-19 vaccine, but in doing so has placed restrictions on it…

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New discovery about how acetaminophen works could improve understanding about pain relievers

, 2025-05-16 15:41:00 Credit: Cell Reports Medicine (2025). DOI: 10.1016/j.xcrm.2025.102139 A new study from Indiana University scientists may aid the pharmaceutical industry in better understanding a popular over-the-counter pain reliever: Tylenol. Michaela Dvorakova, a postdoctoral researcher at IU’s Gill Institute for Neuroscience and the College of Arts and Sciences’ Department of Psychological and Brain Sciences,…

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Study shows infant immune systems respond differently to severe COVID-19

, 2025-05-16 15:42:00 a) Study design. b) Viral load quantification across the three pCoV groups. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-59411-z Infants hospitalized with severe COVID-19 have significantly different immune responses than adults or older children. The finding comes from scientists at St. Jude Children’s Research Hospital, The Jackson Laboratory for Genomic Medicine, Weill Cornell…

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