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Readout Newsletter: Compass, Nektar, Centivax, Curevo

Meghana Keshavan , 2025-06-24 14:11:00 Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Morning! Today, we talk about the readout of Compass Pathways’ psilocybin trial for major depressive disorder, see more vaccine concern and turnover at the FDA, and report from the…

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Doctors back GPs who refuse to follow “ludicrous and unsafe” hospital prescribing practices

Rebecca Coombes , 2025-06-24 11:11:00 BMA representatives have voted to support GPs who refuse to prescribe medicines for hospital patients unless the GP has been properly informed and the treatment has been started and stabilised in secondary care. Representatives also backed GPs who reject initial prescriptions from hospital staff who are not qualified to prescribe,…

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Gene editing treats smooth muscle disease in preclinical model

, 2025-06-24 14:04:00 Base editing, a gene editing technique that swaps one “letter” of the genetic code for another, successfully converted aorta-derived smooth muscle cells carrying a mutation in the ACTA2 gene (center) to healthy cells (right) that matched the form and function of the normal aorta (left). Credit: Circulation (2025). DOI: 10.1161/CIRCULATIONAHA.125.074218 Using gene…

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Malaria protein plays dual role in immune evasion and activation

, 2025-06-24 13:49:00 Researchers from The University of Osaka find that a protein expressed on malaria-infected red blood cells both hides it from the immune system and activates cells to destroy it, making it a promising target for vaccine development. Malaria is a life-threatening disease affecting people globally. It is spread by mosquitoes carrying Plasmodium…

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PROSPER Together Founder Urges a Shift Toward Community Connection

, 2025-06-24 06:58:00 For decades, the conversation around suicide prevention has been largely dominated by clinical procedures and emergency interventions. But Dr. Kent Corso, a clinical psychologist and founder of PROSPER Together, believes it’s time to shift that narrative and the responsibility back to where it belongs: the community. Dr. Corso, whose organization partners closely…

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Consulting room to let – Dublin 2

brendan , 2025-06-24 10:04:00 Spacious and airy consulting room to let in Medical Practice. Prime location in Dublin 2, situated at Leeson Street Bridge, accessible by all major transport links. Room area is 4.13m x 4.27m, 18.48 sq.m. with stunning views over the Grand Canal. View by Appointment only – contact – adelaidepractice@gmail.com or +353…

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Nuvalent’s targeted lung cancer drug shrinks tumors

Matthew Herper , 2025-06-24 10:32:00 The biotech firm Nuvalent said Tuesday that new data indicate its targeted drug zidesamtinib could help patients with a rare form of lung cancer that has failed other treatments. For 1% to 2% of patients with non-small cell lung cancer, tumors test positive for alterations in a gene called ROS1….

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Can monoclonal antibodies effectively treat malaria? Scientists say the answer is a resounding ‘yes’

, 2025-06-24 11:00:00 Credit: Pixabay/CC0 Public Domain Monoclonal antibodies provide protection against a wide range of infectious microbes, and now, in a series of elegant laboratory experiments, scientists have uncovered how a pair of these lab-engineered molecules fight malaria. The newly developed antibodies have arrived at a critical time. Gains against mosquitoes in the years-long…

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Probiotics remain potent in simple plant-based drinks

, 2025-06-24 10:44:00 In a first-of-its-kind test, scientists show that non-encapsulated probiotics can thrive in fruit and vegetable juices, staying fresh, flavorful, and functional from shelf to sip. Study: Developing Novel Plant-Based Probiotic Beverages: A Study on Viability and Physicochemical and Sensory Stability. Image credit: Aninka Bongers-Sutherland/Shutterstock.com Probiotics have soared in popularity because of their health benefits….

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Head-to-Head Trial Finds Winner for CRSwNP With Asthma

, 2025-06-24 10:41:00 Dupilumab significantly outperformed omalizumab in reducing the size of nasal polyps and improving sense of smell in adults with severe chronic rhinosinusitis with nasal polyps (CRSwNP) and coexisting asthma, according to the head-to-head EVEREST phase 4 biologics trial. The study is the first to demonstrate the superiority of dupilumab over omalizumab across…

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A Hospital Group Pioneers Life-Changing 3D-Printed Implants

, 2025-06-24 06:59:00 Vinmec Healthcare System, a leading private hospital group in Vietnam, is transforming bone cancer care with personalized 3D-printed implants, offering new hope to patients previously facing amputation or lifelong disability. In a global first, eight-year-old Tran Minh Duc received a fully 3D-printed, growth-adaptive titanium femur after being diagnosed with aggressive osteosarcoma. Multiple…

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The Medicaid Reckoning: Era of Fiscal and Policy Flux

Adam S. Herbst , 2025-06-23 13:27:00 Medicaid today stands at the center of one of the most complex challenges in American healthcare: how to preserve a program that is financially massive, legally entrenched, and socially indispensable, while also subject to continuous political debate and structural uncertainty. It is no longer enough to describe Medicaid as…

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Push To Move OB-GYN Exam Out of Texas Is Piece of AGs’ Broader Reproductive Rights Campaign

Annie Sciacca , 2025-06-24 09:00:00 Democratic state attorneys general led by those from California, New York, and Massachusetts are pressuring medical professional groups to defend reproductive rights, including medication abortion, emergency abortions, and travel between states for health care in response to recent increases in the number of abortion bans. The American Medical Association adopted…

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Robotic system developed to treat life-threatening tension pneumothorax remotely

, 2025-06-24 08:22:00 Researcher Carolin Müller from TUM Klinikum presents a new robotic module developed for cases of tension pneumothorax. Credit: Technical University Munich Researchers at the Technical University of Munich (TUM) have developed a medical robotic system to relieve a life-threatening tension pneumothorax in the chest cavity. The researchers are presenting the robotic solution…

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Simpler virus testing approach could reduce unnecessary PCR tests in high-risk settings

, 2025-06-24 07:05:00 The COVID-19 pandemic yielded important advances in testing for respiratory viruses, but it also exposed important unmet needs in screening to prevent the spread of infections in high-risk settings. While PCR (polymerase chain reaction) tests are the gold standard for detecting viral infections, they remain a challenge for screening large numbers of…

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Liver Transplantation May Reduce Colorectal Neoplasia Risk

, 2025-06-24 07:58:00 TOPLINE: In patients with primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD), liver transplantation was associated with a 34% reduction in the risk for colorectal neoplasia. However, 21% of transplant recipients still developed neoplasia. METHODOLOGY: PSC affects 4%-8% of patients with IBD, increasing their risk for colorectal neoplasia. About 40% of…

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Dr. Klaus Rentrop Shares Acute Myocardial Infarction: Part 4

, 2025-06-24 06:59:00 Dr. Klaus Rentrop describes how three scientific errors withheld lifesaving treatments for heart attacks from patients for 30 years. In 1880, Dr Karl Weigert, a German pathologist, described the cause of heart attacks: A blood clot (thrombus) forms in one of the heart’s arteries at a spot already narrowed by atherosclerosis. Complete…

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The Overlooked Global Warming Cost We Can’t Ignore

Gary Falcetano , 2025-06-23 14:17:00 Beyond being an environmental issue, climate change is a serious threat to public health, especially for individuals with food and respiratory allergies. A recent review in Laryngoscope found that climate change is altering pollen seasons and concentrations, allergic rhinitis (AR) disease prevalence, allergy sensitization, and AR symptom severity. Projections suggest…

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Living Without Health Insurance? We Want To Hear From You 

, 2025-06-22 21:00:00 Thank you for your interest in supporting Kaiser Health News (KHN), the nation’s leading nonprofit newsroom focused on health and health policy. We distribute our journalism for free and without advertising through media partners of all sizes and in communities large and small. We appreciate all forms of engagement from our readers…

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GLP-1 drugs effective for type 1 diabetes in new study| STAT

Elizabeth Cooney , 2025-06-23 20:15:00 Elizabeth Cooney is a cardiovascular disease reporter at STAT, covering heart, stroke, and metabolic conditions. You can reach Liz on Signal at LizC.22. Obesity drugs were first approved to treat type 2 diabetes, but there’s a growing movement to test them in type 1 diabetes, too. Research presented Monday at…

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Addictive symptoms more important than time spent on phone in predicting suicidal thoughts in young people, study finds

Jane Feinmann , 2025-06-20 13:56:00 Children who develop addictive use of digital technology have up to twice the risk of developing suicidal behaviour within four years compared with those who may spend longer on their phones but don’t develop addictive behaviour, a study has found.1 The research involved regular screening over four years for addictive…

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‘Pill-on-a-thread’ could replace endoscopies for half of all patients being monitored for esophageal cancer risk

, 2025-06-23 22:30:00 Professor Rebecca Fitzgerald demonstrates the capsule sponge. Credit: StillVision Endoscopies could be replaced by far less invasive capsule sponge tests for half of all patients with Barrett’s esophagus, a known precursor to esophageal cancer, according to a new study by researchers at the University of Cambridge, Addenbrooke’s Hospital and Queen Mary University…

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Federal Proposals Threaten Provider Taxes

, 2025-06-24 05:31:00 Republican efforts to restrict taxes on hospitals, health plans, and other providers that states use to help fund their Medicaid programs could strip them of tens of billions of dollars. The move could shrink access to healthcare for some of the nation’s poorest and most vulnerable people, warn analysts, patient advocates, and…

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Semaglutide benefits extend to type 1 diabetes

Scott Buzby , 2025-06-23 21:42:00 Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process your request. Please try again later….

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Health insurers’ prior authorization promise: Will it help? | STAT

Tara Bannow and Chelsea Cirruzzo , 2025-06-23 20:50:00 Tara Bannow covers hospitals, providers, and insurers. You can reach Tara on Signal at tarabannow.70. WASHINGTON — Last week’s pledge from more than 40 health insurers to cut down on prior authorizations came after some behind-the-scenes convincing from the Trump administration.  The administration pushed insurers to sign…

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Hamish McClelland | The BMJ

Helen McClelland, Alan Kerr , 2025-06-23 07:41:00 Helen McClelland, Alan Kerr Hamish was brought up in South Shields, Tyne and Wear, and was educated at St Bees boarding school in Cumbria. He studied medicine at Newcastle Medical School, qualifying in 1952. After national service in Hong Kong he undertook general medical training in the south…

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Phase III trial shows gene therapy skin grafts help heal chronic wounds in blistering skin disease

, 2025-06-23 22:30:00 Credit: Pixabay/CC0 Public Domain Skin grafts genetically engineered from a patient’s own cells can heal persistent wounds in people with an extremely painful dermatologic disease, a Stanford Medicine-led clinical trial has shown. The grafts treat severe dystrophic epidermolysis bullosa, or EB, a genetic condition in which the skin is so fragile the…

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Genetically engineered skin grafts help heal chronic wounds in patients with epidermolysis bullosa

, 2025-06-24 03:06:00 Skin grafts genetically engineered from a patient’s own cells can heal persistent wounds in people with an extremely painful dermatologic disease, a Stanford Medicine-led clinical trial has shown. The grafts treat severe dystrophic epidermolysis bullosa, or EB, a genetic condition in which the skin is so fragile the slightest touch can cause…

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AID Systems Need Upgrades for Premenopausal Glucose Control

, 2025-06-23 20:48:00 Insulin requirements fluctuated significantly throughout the menstrual cycle without a consistent pattern, prompting a substantial proportion of premenopausal women with type 1 diabetes (T1D) to manually adjust their automated insulin delivery (AID) system settings to achieve better glycemic control. METHODOLOGY: Although insulin requirements vary across phases of the menstrual cycle, understanding specific…

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Arkangel AI Helps Physicians Reduce Up To 79% Of Their Time

, 2025-06-12 18:10:00 You’re a doctor, nurse, specialist, or hospital administrator—navigating a fast-paced, high-stakes environment every day. Between caring for patients, documenting charts, and keeping up with the latest research, your time is stretched thin. Yet, one challenge remains constant: quickly finding reliable, evidence-based answers when you need them most. Now imagine cutting down the…

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New US Veterans Administration rules remove language barring discrimination

Owen Dyer , 2025-06-23 15:25:00 Byelaws governing hiring, firing, and treatment in the largest integrated US healthcare system, the Veterans Administration (VA), no longer contain text explicitly barring discrimination against staff and job applicants on the grounds of “lawful partisan political affiliation.” The changes were seemingly made without consultation with doctors and others working under…

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