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UC engineers develop saliva test to detect depression and anxiety

, 2025-05-09 02:08:00 University of Cincinnati engineers created a new device to help doctors diagnose depression and anxiety. UC College of Engineering and Applied Science Distinguished Research Professor Chong Ahn and his students developed a “lab-on-a-chip” device that measures the stress hormone cortisol from a patient’s saliva. Knowing if a patient has elevated stress hormones…

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Efruxifermin Shows Fibrosis Reduction in MASH Cirrhosis

, 2025-05-09 16:31:00 AMSTERDAM — A once daily, 50 mg dose of efruxifermin reduced fibrosis at 96 weeks in patients with compensated cirrhosis due to metabolic dysfunction-associated steatohepatitis (MASH) compared with placebo, but it did not significantly reduce fibrosis at 36 weeks (primary endpoint), according to results from the phase 2b SYMMETRY trial. Efruxifermin is…

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AI’s Next Act: New Medicines

Doug Selinger , 2025-05-09 14:17:00 Bringing a new drug to market is staggeringly inefficient: About 90% of new drugs fail in clinical trials, development times are 10-15 years, and the costs can run in excess of $2 billion dollars. It’s hard to think of an endeavor more in need of a boost from AI, and…

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AI guidelines highlight its potential in personalised healthcare and reducing overcrowding

Michael McHale , 2025-05-09 07:30:00 Pilot project at St Vincent’s Hospital is currently testing AI’s potential role in performing heart ultrasound scans The development of personalised healthcare plans and predicting patient inflows to reduce overcrowding are among the tasks that artificial intelligence (AI) could assist, according to new Government guidelines on the use of the…

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Why Pharmacy Law Knowledge Is Vital for Patient Safety

MNB Guest , 2025-05-09 13:08:00 Pharmacy law sets a standard that protects patients and prevents medication misuse. Therefore, pharmacy as a profession is incomplete without these laws. They are a foundation on which pharmacists serve. In addition, these guidelines explain the legal implications of failing to operate within the law. For instance, they say the…

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TSOLife raises $43M to expedite product development

, 2025-05-09 13:27:00 Resident insight and experience platform TSOLife scored $43 million in a Series B funding round led by PeakSpan Capital, bringing the company’s total funding to $52 million. WHAT IT DOES  TSOLife’s AI platform, Minerva, simplifies data creation via embedded analytics, allowing senior living communities to collect and use data to aid in…

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Heart rhythm disorder traced to bacterium lurking in gums

, 2025-05-09 14:55:00 Immunohistochemical staining in mice shows Porphyromonas gingivalis (green) entering cardiac muscle through small blood vessels in the left atrium. Credit: Shunsuke Miyauchi/Hiroshima University Tempted to skip the floss? Your heart might thank you if you don’t. A new study from Hiroshima University (HU) finds that the gum disease bacterium Porphyromonas gingivalis (P….

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St. Jude Children’s scientists use brain organoids to study rare encephalopathy

, 2025-05-09 02:12:00 While extremely rare, encephalopathy (a condition affecting brain function) triggered by mutations in the UBA5 gene has devastating impacts, with affected individuals reaching few developmental milestones and experiencing frequent and early-onset seizures. Scientists at St. Jude Children’s Research Hospital created a first-of-its-kind cortical organoid model for the disorder, studying how it causes…

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Efimosfermin Leads to Significant MASH Improvement

, 2025-05-09 13:01:00 SAN DIEGO — Boston Pharmaceuticals’ once-monthly efimosfermin alfa (formerly BOS-580) prescribed for metabolic dysfunction–associated steatohepatitis (MASH) with F2 and F3 fibrosis significantly improved MASH resolution and fibrosis after 24 weeks, according to results of a phase 2 trial presented at Digestive Disease Week (DDW) 2025. An analogue of the fibroblast growth factor…

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9 Ways to Find Caregivers With Flexible Scheduling Options

Luidgi Faubert , 2025-05-09 13:43:00 Finding a caregiver who meets your care needs and schedule requires planning and the right tools. Flexible caregiving is key for those with changing routines, shift work or evolving health needs. Look for services that let you filter by availability, experience and specialization to match your exact situation. How Do…

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Honey, Sweetie, Dearie: The Perils of Elderspeak

Paula Span , 2025-05-09 09:00:00 A prime example of elderspeak: Cindy Smith was visiting her father in his assisted living apartment in Roseville, California. An aide who was trying to induce him to do something —  Smith no longer remembers exactly what — said, “Let me help you, sweetheart.” “He just gave her The Look…

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Aboriginal and Torres Strait Islander women and breast cancer

, 2025-05-09 12:18:00 Credit: Pixabay/CC0 Public Domain Researchers have sought to improve our understanding of why Aboriginal and Torres Strait Islander women (respectfully referred to hereon as Aboriginal) with breast cancer can have poorer outcomes than non-Aboriginal women. Their study was co-designed with the Aboriginal community and sought to better understand why Aboriginal women in…

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COPD and Rising Temperatures: Mitigating Patient Risk

, 2025-05-09 11:16:00 For some patients with chronic obstructive pulmonary disease (COPD), summer can be one of the most stressful times of the year. Not only is allergy season in full swing, but rising temperatures and humidity can prompt COPD flare-ups.  Major changes in humidity levels can lead to worsening symptoms for those with COPD….

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Emergency medicine residency should not be extended by a year

Blake R. Denley , 2025-05-09 08:30:00 Less than two years ago, I completed a three-year emergency medicine residency and, after passing written and oral board exams, became a board-certified emergency physician. Now, the Accreditation Council for Graduate Medical Education is claiming that three years of personal and financial sacrifice are not enough.  The ACGME reviews…

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Precision nano therapy targets tumor nerves in pancreatic cancer

, 2025-05-09 02:37:00 Announcing a new publication for Acta Materia Medica journal. A preclinical study has developed a precision nano-intervention strategy targeting tumor-associated nerves to destroy nerve-fueled tumor growth in pancreatic cancer. In this strategy, Escherichia coli Nissle 1917-derived outer membrane vesicles (OMVs) are decorated with nerve-binding peptide for targeted delivery of co-loaded tropomyosin receptor…

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Finasteride Linked to Suicidal Ideation

, 2025-05-09 09:38:00 The European Medicines Agency (EMA) has confirmed that suicidal ideation is a potential side effect of finasteride and urged healthcare professionals to advise patients to stop treatment and seek medical advice if they experience depressed mood, depression, or suicidal thoughts. The advice follows an EU-wide review launched in February of available data…

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A new era for patient safety: mandatory open disclosure

Contributor , 2025-05-09 07:30:00 Janet Keane is a Director in DWF’s Healthcare Team based in Dublin, and is a highly experienced and specialist Clinical Negligence Solicitor, having amassed over 15 years’ experience, primarily in the Medical Defence industry, representing GPs, Consultants, and Private Hospitals A landmark shift in Irish healthcare has arrived with the commencement…

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A California Lawmaker Leans Into Her Medical Training in Fight for Health Safety Net

Christine Mai-Duc , 2025-05-09 09:00:00 SACRAMENTO, Calif. — State Sen. Akilah Weber Pierson anticipates that California’s sprawling Medicaid program, known as Medi-Cal, may need to be dialed back after Gov. Gavin Newsom releases his latest budget, which could reflect a multibillion-dollar deficit. Even so, the physician-turned-lawmaker, who was elected to the state Senate in November,…

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As Trump attacks on Harvard intensify, researchers scramble

Brooke Hauser — Boston Globe , 2025-05-09 08:30:00 What would Harvard University be without the money the federal government has provided over decades to underwrite its vast research initiatives? That’s the existential, $9 billion question facing the Harvard community after the Trump administration’s most recent threat in its confrontation with the university: Harvard will not…

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Health care workers, firefighters have increased PFAS levels, study finds

, 2025-05-09 08:29:00 Credit: Pixabay from Pexels A study including researchers from the University of Arizona Health Sciences and published in the Journal of Exposure Science & Environmental Epidemiology found that firefighters had higher concentrations of certain per- and polyfluoroalkyl substances, or PFAS, and health care workers had moderate elevations of PFAS in their blood…

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Why your baby’s first steps may be written in their DNA

, 2025-05-09 02:41:00 A landmark study shows that when babies start walking isn’t just developmental, it’s in their DNA. Genetic variants not only shape motor timing but also link to cognitive traits and brain structure. Thresholding t-statistic image at t > 0.95 (two-sided statistical test). Significant voxels were overlaid on the 40-week neonatal brain template in sagittal, coronal and…

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No Benefit to ERCP With Sphincterotomy in Pancreas Divisum

, 2025-05-09 07:40:00 SAN DIEGO — In treating pancreas divisum, the common use of endoscopic retrograde cholangiopancreatography (ERCP) with minor papilla endoscopic sphincterotomy showed no significant benefit over a sham procedure, suggesting that patients can be spared the intervention, which can carry risks of its own. “This is a topic that has been debated for…

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Longevity Shot? Single Jab May Extend Lifespan By 16 Years

, 2025-05-09 06:59:00 Scientists around the world are racing to unlock the secrets of longer, healthier lives. From promoting exercise and sleep to exploring longevity-boosting diets, they have identified a range of strategies that could help slow the aging process. Now, a groundbreaking new study in mice suggests that the key to extending lifespan might…

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 Early-onset cancer: the types that are on the rise

Associated Press , 2025-05-08 14:16:00 Cancer before age 50 is rare, but increasing, in the United States and researchers want to know why. A new government study provides the most complete picture yet of early-onset cancers, finding that the largest increases are in breast, colorectal, kidney and uterine cancers. Scientists from the National Cancer Institute looked…

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PFAS influence cellular immune response to coronavirus, research finds

, 2025-05-08 20:19:00 Graphical abstract. Credit: Environment International (2025). DOI: 10.1016/j.envint.2025.109409 PFAS are found in multiple everyday products, such as cosmetics, outdoor clothing and coated pans. This is because of their special properties. They are heat-resistant and repel water and grease. There are thousands of different PFAS compounds and they are found in the soil,…

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Study reveals regional risk factors driving heart disease in Asia and Oceania

, 2025-05-09 02:41:00 A new study puts the spotlight on the rising burden of ischemic heart disease across Southeast Asia, East Asia and Oceania, and calls for localized, equity-focused interventions in these regions. The researchers identified region-specific, modifiable risk factors that influence the increasing prevalence of ischemic heart disease, such as toxic air pollution in…

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Why RFK Jr.’s data plans might hit a real world snag

Mario Aguilar , 2025-05-08 15:13:00 You’re reading the web edition of STAT’s Health Tech newsletter, our guide to how technology is transforming the life sciences. Sign up to get it delivered in your inbox every Tuesday and Thursday. Federal health department leaders have touted the potential of using patient data, including health records, to study autism, chronic disease,…

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Biological age can predict cardiovascular disease morbidity and mortality

, 2025-05-08 20:21:00 Credit: Aphiwat chuangchoem from Pexels Looking at your biological age—how old your body really is—can give a clearer picture of your heart disease risk than traditional tools alone. This finding comes from a newly published multicenter study conducted in collaboration between the Universities of Jyväskylä, Tampere, and Helsinki, the Finnish Institute for…

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Hyperlactataemia Tied to Poor Mortality in Patients With AKI

, 2025-05-08 12:00:00 TOPLINE: Serum lactate levels of more than 4 mmol/L on admission to the intensive care unit (ICU) were associated with an increased rate of 60-day mortality in patients with acute kidney injury (AKI) receiving renal replacement therapy (RRT). METHODOLOGY: Researchers conducted a retrospective study over a 4-year period to examine the effect of…

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