Aliaa Barakat , 2025-04-15 08:30:00 “Yes,” I said reluctantly to the urgent care provider who entered the exam room to see me that January morning, “I am OK with that.” She asked for consent to record our conversation “for the purposes of producing a draft of the encounter documentation.” The evening before, I wasn’t feeling…
, 2025-04-15 09:39:00 Credit: Cellular and Molecular Gastroenterology and Hepatology (2025). DOI: 10.1016/j.jcmgh.2025.101503 Research on gastrointestinal diseases, especially cancer, has mainly focused on epithelial cells, which line the surfaces of organs, are important for various functions, and are believed to be the cells that go awry to cause these diseases. However, studying these cells using…
, 2025-04-15 08:25:00 London Lab Live 2025 will make its debut on 14–15 May 2025 at ExCeL London, offering a major new platform for professionals across the laboratory sector. From pharmaceuticals and biotech to food and beverage, chemicals, and academia, the event is set to become the UK’s central meeting point for scientific innovation and…
, 2025-04-15 09:43:00 TOPLINE: Janus kinase (JAK) inhibitors led to improvement of uveitis in approximately half of pediatric patients previously treated with disease-modifying antirheumatic drugs (DMARDs) in a case series. METHODOLOGY: The researchers reported a case series from five US and Italian centers on patients under 21 years old who were treated with at least…
, 2025-04-15 07:47:00 For six long years, 27-year-old Anna Gray from Bath, England, has been unable to do something most people take for granted: urinate on her own. Diagnosed with the rare and little-understood Fowler’s Syndrome, she must self-catheterize five times a day just to relieve her bladder. With no known cure and causes that…
Michael Millie , 2025-04-08 13:55:00 It is well documented that access to primary care in the U.S. is decreasing. The cause is multi-factorial. Some of the problems are a result of patient-related factors, such as mobility and location, but a large part is due to physician shortages. In fact, a new report from the Human…
Dr Ray O’Connor , 2025-04-15 07:30:00 Dr Ray O’Connor takes a look at the latest clinical articles on the subject of hypertension Hypertension (Part 1)Hypertension can be effectively treated with antihypertensive medication, which has been proven to lower the risk of stroke and cardiovascular diseases across all age groups. Even in patients older than 80…
Victoria Langowska , 2025-04-14 16:24:00 April 14, 2025 1 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Theresa Gaffney , 2025-04-14 13:07:00 Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds. Sign up here. Good morning. For those who were curious, our turkey friend at STAT headquarters last week was indeed a wild turkey, not a turkey vulture. A number of images from different angles, checked with…
, 2025-04-15 06:00:00 Credit: Pixabay/CC0 Public Domain People with a certain heart valve abnormality are at increased risk of severe heart rhythm disorders, even after successful valve surgery. This is according to a new study, “Mitral annular disjunction and mitral valve prolapse: long-term risk of ventricular arrhythmias after surgery” from Karolinska Institutet and Karolinska University…
, 2025-04-15 05:53:00 A high-level conference convened in Warsaw under the auspices of the Polish Presidency of the Council of the European Union highlighted the importance of adopting a comprehensive Europe-wide policy framework on rare diseases. Image Credit: European Economic and Social Committee (EESC) The European Union needs a European Action Plan on Rare Diseases…
, 2025-04-15 05:10:00 The European Union (EU) has introduced its “Preparedness Union Strategy,” designed to strengthen resilience in emergencies such as natural disasters, pandemics, cyberattacks, and armed conflict. This initiative is inspired by models already adopted in Scandinavian countries, such as Finland, Sweden, and Denmark, which have implemented similar measures to prepare their populations for…
Frank Vinluan , 2025-04-08 17:57:00 Immunology continues to be one of the most active areas for drug research as the field aims to bring patients new ways to eliminate the antibodies driving autoimmune disease, but in a manner that does not also compromise the immune system. Merida Biosciences, a startup formed by venture capital firm…
Victoria Langowska , 2025-04-14 16:31:00 April 14, 2025 1 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Kara Miller — Boston Globe , 2025-04-14 13:24:00 As the months ticked by in his job search, Albert started to wonder if there was something wrong with him. He got advice on how to regulate his emotions, and how to be more self-confident. But after on-site interviews with seven companies — and no offers —…
Abi Rimmer , 2025-04-14 09:21:00 Going through fertility treatment can be physically and mentally exhausting, especially when working at the same time, but there are ways you can ease the strain, Abi Rimmer hears Be kind to yourself Divpreet Sacha, general practice specialty registrar, Birmingham and Solihull, says, “In vitro fertilisation (IVF) is becoming increasingly…
, 2025-04-15 04:10:00 Research suggests children may breathe and absorb plasticizers called phthalates, flame retardants, and other harmful chemicals from their mattresses while they sleep. Credit: University of Toronto Babies and young children may breathe and absorb plasticizers called phthalates, flame retardants, and other harmful chemicals from their mattresses while they sleep, according to a…
, 2025-04-15 02:01:00 Can lithium’s effect on daily activity patterns reveal who will benefit from treatment? A six-week trial finds circadian shifts emerge early, before mood improves, hinting at a biological clue to lithium response in bipolar disorder. Study: Effect of lithium on circadian activity level and flexibility in patients with bipolar disorder: results from…
, 2025-04-15 04:05:00 TOPLINE: The use of cancer drugs with withdrawn US Food and Drug Administration (FDA) accelerated approval indications declined significantly after publication of negative confirmatory trials, despite the drugs remaining available for off-label use, a cohort study found. METHODOLOGY: The FDA’s accelerated approval program allows drugs for serious conditions to enter the market…
Marissa Plescia , 2025-04-08 21:57:00 Late last week, the Trump administration’s CMS announced that it is not finalizing a provision proposed by the Biden administration that would expand coverage of anti-obesity drugs under Medicare and Medicaid. Currently, Medicare and Medicaid are required to cover GLP-1s like Ozempic and Wegovy for conditions like diabetes, but Medicare…
Victoria Langowska , 2025-04-14 16:37:00 April 14, 2025 1 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Ed Silverman , 2025-04-14 13:28:00 Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and refreshing because, once again, that predictable routine of meetings, deadlines, and the like has returned. After all, the world keeps spinning. And to cope, yes, we are relying on cups of stimulation to…
Gary S Collins , 2025-04-14 22:00:00 Gary S Collins, professor of medical statistics 1Centre for Statistics in Medicine, UK EQUATOR Centre, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford, UK gary.collins{at}csm.ox.ac.uk (or @GSCollins on X and @gscollins.bsky.social on Bluesky) Reporting guidelines have become an essential instrument of scientific integrity. We need…
, 2025-04-14 20:55:00 Credit: Pixabay/CC0 Public Domain Researchers from the Epilepsy Neurogenetics Initiative (ENGIN) at Children’s Hospital of Philadelphia (CHOP) have completed a comprehensive natural history study of SCN8A-related disorders, which represent a spectrum of neurological symptoms. The study, using retrospective clinical information analyzed through novel data analysis methods, revealed a range of seizure types…
, 2025-04-15 02:38:00 Could a 45-minute weekly digital coach be the key to reversing diabetes? New study of 130k+ adults shows dramatic risk reduction and remission rates, without pills or extreme diets. Study: Lifestyle Modification in Prediabetes and Diabetes: A Large Population Analysis. Image Credit: RSplaneta / Shutterstock In a recent article published in the journal Nutrients,…
, 2025-04-14 13:01:00 TOPLINE: Recent lithium and valproate use was associated with a 34%-46% lower risk for suicide in patients with schizophrenia or bipolar disorder (BD), investigators leading a large cohort study reported. METHODOLOGY: In a retrospective cohort study, data were analyzed from the National Health Information Database in South Korea. The study included more…
Marissa Plescia , 2025-04-14 22:43:00 It’s no secret that small to mid-sized businesses are struggling to handle healthcare costs, and a report released last week from JPMorganChase Institute is adding to that evidence. The report found that roughly one-third of small businesses discontinued their health insurance coverage from one year to the next. For instance,…
Caitlyn Stulpin , 2025-04-14 17:53:00 April 14, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Ed Silverman , 2025-04-15 00:03:00 Dozens of state attorneys general are urging Congress to pass a law prohibiting pharmacy benefit managers from simultaneously owning pharmacies, arguing such a move would boost competition and create more affordable prescription drug prices for Americans. Their concern is these arrangements create conflicts of interest that allow pharmacy benefits managers…
Kenneth F Schulz, David Moher , 2025-04-14 22:00:00 Kenneth F Schulz, adjunct clinical professor1, David Moher, senior scientist2 1Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina at Chapel Hill, NC, USA 2Centre for Journalology, Methodological and Implementation Research Program, Ottawa Hospital Research Institute Correspondence to: kfschulz{at}ad.unc.edu Kenneth F Schulz and David…
, 2025-04-14 20:56:00 by I. Edwards Fisher-Price has recalled 253,000 baby stroller toys in the U.S. because of a choking risk, according to the U.S. Consumer Product Safety Commission (CPSC). An additional 4,500 toys sold in Canada have also been recalled, according to a report from CBS News. The recall involves the “Brunch & Go”…
, 2025-04-15 00:42:00 Scientists have developed a fast, non-invasive blood test that can detect Parkinson’s disease before tremors begin. By measuring RNA fragments that reflect brain pathology, the test offers new hope for early diagnosis and targeted intervention. Study: Pre-symptomatic Parkinson’s disease blood test quantifying repetitive sequence motifs in transfer RNA fragments. Image Credit: Kateryna Kon /…
, 2025-04-14 13:53:00 Skin cancer patients are set to be fast-tracked into a clinical trial for a new cancer vaccine, NHS England has announced. The vaccine, called iSCIB1+, is designed to help the immune system better recognise and attack cancer cells. It is being tested in a phase 2 trial known as the SCOPE study. …
Katie Adams , 2025-04-14 23:34:00 Cofertility, a Los Angeles-based startup aimed at making family-building more equitable and accessible, closed a $7.25 million Series A funding round this month. The financing round — which brings Cofertility’s total funding to date to $16 million — was led by Next Ventures and Offline Ventures. The company launched in…
Michela Cimberle , 2025-04-14 17:55:00 April 14, 2025 5 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Ed Silverman , 2025-04-14 17:05:00 Canadian officials have obtained a court order that requires Express Scripts to produce documents in connection with an investigation into whether the pharmacy benefits manager violated antitrust laws. The Competition Bureau is examining whether the company forced or induced Canadians to use its own pharmacies. Express Scripts operates four mail-order…
Sally Hopewell, An–Wen Chan, Gary S Collins, Asbȷorn Hrobȷartsson, David Moher, Kenneth F Schulz, Ruth Tunn, Rakesh Aggarwal, Michael Berkwits, Jesse A Berlin, Nita Bhandari, Nancy J Butcher, Marion K Campbell, Runcie C W Chidebe, Diana Elbourne, Andrew Farmer, Dean A Fergusson, Robert M Golub, Steven N Goodman, Tammy C Hoffmann, John P A Ioannidis,…
, 2025-04-14 21:00:00 Credit: Unsplash/CC0 Public Domain A cross-sectional analysis of firearm injury-related emergency department (ED) visits found that between 2018 and 2023, there was approximately one firearm injury ED visit every 30 minutes in the 10 jurisdictions studied. The analysis also found that rates of firearm-related ED visits were often highest during evenings, weekends,…
, 2025-04-14 13:59:00 UNIGE scientists identified a brain circuit where lies the origin the social difficulties experienced by people with autism spectrum disorders. From birth, human survival depends on the ability to engage with others. This ability, which is essential for development, seems to be impaired very early on in children with autism spectrum disorders…
, 2025-04-14 14:35:00 The US Food and Drug Administration (FDA) has approved a prefilled syringe for self-injection of efgartigimod alfa and hyaluronidase-qvfc (Vyvgart Hytrulo, argenx) in the treatment of adults with generalized myasthenia gravis (gMG) who are anti-acetylcholine receptor antibody positive and adults with chronic inflammatory demyelinating polyneuropathy (CIDP). The prefilled syringe will be available as…
, 2025-04-04 08:35:00 At 41, most people are juggling careers, families, and future plans, not bracing for a diagnosis of Alzheimer’s. But that’s exactly what happened to a dad from Australia, who is now spreading awareness of a little-known reality: Alzheimer’s is not just a disease of old age. Fraser was diagnosed with young-onset Alzheimer’s,…
Katie Adams , 2025-04-09 00:56:00 There is much variation across the country in terms of how far along health systems are in their AI deployment journey, with some hospitals still in cautious experimentation mode and others already scaling tools across multiple clinical and operational settings, noted Andy Crowder, chief digital officer at Advocate Health, in…
, 2025-04-14 18:05:00 The White House Office of Management and Budget (OMB) released two memos directed to the heads of all executive branch departments and agencies establishing policies on federal AI use and purchase of AI in government. The memos, which align with an Executive Order President Donald Trump signed in January, replace former President…
Shari M. Erickson, MPH; John C. Schoen, MA; Andrew (Drew) Rhoades , 2025-04-14 18:26:00 April 14, 2025 5 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . ” data-action=subscribe> Subscribe We were…
Ed Silverman , 2025-04-14 20:49:00 The Trump administration disclosed it formally opened an investigation into the extent to which the importation of certain pharmaceuticals may threaten national security, a move that is a widely anticipated prelude to imposing tariffs on a potentially large number of medicines. In a Federal Register notice published on Monday, the…
Adrian O’Dowd , 2025-04-14 15:11:00 The UK National Institute for Health and Care Excellence has recommended a targeted twice daily drug treatment that could help around 3000 women a year with advanced breast cancer in England and Wales. In final draft guidance published on 11 April,1 NICE said it was recommending capivasertib (also called Truqap)…
, 2025-04-14 20:40:00 Graphical abstract. Credit: The Journal of Molecular Diagnostics (2025). DOI: 10.1016/j.jmoldx.2025.01.003 Researchers have demonstrated the potential of the innovative optical genome mapping (OGM) technique for the diagnosis, prognosis, and therapeutic management of multiple myeloma. This new study in The Journal of Molecular Diagnostics, details how this novel method can establish the cytogenomic…
, 2025-04-14 16:10:00 Complications during pregnancy (or adverse pregnancy outcomes), like gestational diabetes and newly developed high blood pressure, act as nature’s stress test and may uncover an individual’s risk for heart disease later in life, according to new research published in the JACC, the flagship journal of the American College of Cardiology. The study…
, 2025-04-14 19:02:00 The U.S. Food and Drug Administration (FDA) and Novo Nordisk are warning people not to use counterfeit semaglutide 1.0 mg (Ozempic injection) found in the US drug supply chain. Novo Nordisk notified the FDA on April 3, 2025 that several hundred units of the fake product had been distributed outside the company’s…
, 2025-04-07 07:04:00 A school-aged child has died from complications of measles in Texas, marking the second death in this year’s outbreak, which has sickened 481 people and hospitalized 56 since January. The unidentified victim who died of lung failure was not vaccinated and did not have any previous health conditions, health officials revealed. Measles…