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Preconception intake of calcium and zinc linked to lower risk of hypertensive disorders of pregnancy

Higher intake of calcium and zinc before conceiving can reduce the risk of hypertensive disorders during pregnancy, according to research. Preconception nutrition is crucial for a healthy pregnancy, highlighting the importance of adequate intake of essential minerals like calcium and zinc. Studies show that higher pre-conception intake of these minerals is associated with a lower…

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Europe Endorses Its First mRNA Vaccine for RSV

The EMA CHMP has recommended the marketing authorization for the mRNA RSV vaccine mRESVIA to protect adults aged 60 or older from lower respiratory tract disease caused by RSV. RSV is a contagious respiratory virus that can lead to serious consequences in older adults. The vaccine, mRNA-1345, targets the F glycoprotein of RSV to prevent…

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Why Insurers Beat CMS In the MA Star Ratings Battle

Medicare Advantage insurers won a victory as CMS agreed to recalculate Star Ratings following lawsuits from SCAN Health Plan and Elevance Health alleging improper calculations. Star Ratings inform beneficiaries of plan quality and impact funding, with higher ratings receiving more funding. CMS updated how Star Ratings are calculated using the Guardrail Rule to cap cut…

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ASH to present honorific awards to ‘visionary’ hematologists

The ASH Annual Meeting will honor several notable hematologists for their contributions to the field. Among the recipients are Éliane Gluckman for her work in cord blood transplantation, Stuart Orkin and John Tisdale for advancements in hemoglobin disorders treatment, James George for promoting diversity in hematology, Ami Bhatt for genomic research on the microbiome, Sean…

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An ALS moonshot plan barely gets off the ground

The National Academies of Sciences, Engineering, and Medicine released a report on transforming ALS into a manageable, chronic disease within 10 years, but it falls short in accelerating treatment development. ALS is a devastating condition with no effective treatments for 99% of patients. The report focuses on improving access to care, genetic testing, and caregiver…

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Hospital doctors in Wales vote to accept pay offers

Consultants, junior doctors, and SAS doctors in Wales have accepted the government’s pay offers, ending three separate pay disputes. Junior doctors in Wales voted to accept an additional 7.4%, bringing the total uplift to 12.4% for the 2023-24 financial year, with the rise backdated to April 2023. Consultants also voted to accept a revised pay…

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Is Semaglutide Anti-inflammatory?

Research presented at the European Atherosclerosis Society 2024 showed that the anti-obesity drug semaglutide led to significant reductions in the inflammatory marker high-sensitivity C-reactive protein (CRP) in patients with overweight or obesity, regardless of weight loss. The SELECT trial involving over 17,600 patients with cardiovascular disease found that semaglutide lowered CRP levels by 38% compared…

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Pivot Podcast: The Evolution of Pharmacies with Rick Ratliff

The pharmacy industry is experiencing significant changes, with independent pharmacies closing and retail pharmacies struggling. New medication delivery models, like Mark Cuban’s Cost Plus Drug Company and Amazon, are emerging. The pandemic highlighted the valuable role of pharmacists in administering vaccines. In the final episode of Season 2 of the Pivot podcast, Rick Ratliff, former…

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News Flash! Beware Jumping Leeches in Madagascar

Scientists have discovered a species of leech in the rainforests of Madagascar that can jump and soar in the air with acrobatic grace. This behavior, captured on film for the first time, has intrigued the scientific community and sheds light on previously undocumented behaviors of these creatures. The purpose of these jumps, whether to ambush…

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Care enablement company Fabric acquires Walmart’s MeMD

Fabric, a healthcare technology company, has acquired Walmart’s telehealth platform MeMD. MeMD offers virtual medical and behavioral health services to corporate clients, with 24/7 on-demand care and a care coordination team. Fabric uses conversational AI to identify patients’ symptoms and guide them to appropriate care settings. Through the acquisition, Fabric aims to expand its offerings…

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Gene Silencing Benefit of Zodasiran in Hyperlipidemia

Researchers conducted a study on the drug zodasiran, which targets a liver protein and significantly lowers triglyceride and lipoprotein levels in patients with mixed hyperlipidemia on statin therapy. The drug, an siRNA that silences the ANGPTL3 gene, showed promising results in reducing lipid levels and improving cardiovascular health. The reductions in liver fat content with…

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Arcadia & CareJourney Merge to Take Value-Based Care Analytics to Another Level

Health data platform Arcadia recently acquired CareJourney, a health analytics firm focusing on value-based care contracts. This acquisition allows Arcadia to provide a more comprehensive suite of value-based care technology by combining data platforms, analytics, and workflow tools. CareJourney’s dataset includes data across various healthcare plans and providers, giving Arcadia access to valuable insights. The…

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The Saturated Fat Myth | Medical News Bulletin

Georg Hafner PhD’s review of the evidence shows that dietary saturated fat is not a leading cause of heart disease and should not be avoided. Saturated fat is an essential nutrient and there is little evidence to suggest it is harmful when consumed in moderation as part of a balanced diet. Trans fats and hydrogenated…

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Foodsmart secures more than $200M for telenutrition platform

TPG’s The Rise Fund has invested over $200 million into Foodsmart, a telenutrition platform that partners with health plans, employers, and commercial health plan members to provide virtual access to registered dietitians. Foodsmart also offers a digital food benefits management platform for meal planning, grocery ordering, and applying for SNAP benefits. The company works with…

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Journalists Break Down SCOTUS Decision on Purdue Pharma and California’s New Heat Rules

KFF Health News senior correspondent Aneri Pattani discussed the Supreme Court’s Purdue Pharma decision and the opioid settlement on WHYY’s “Studio 2.” KFF Health News ethnic media editor Paula Andalo talked about California’s new heat rules on Radio Bilingüe’s “Línea Abierta.” KFF Health News contributor Andy Miller discussed the impact of social media use on…

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Phase 3 trial of combination for advanced head, neck cancer halted due to lack of benefit

A randomized phase 3 trial evaluating xevinapant with chemoradiotherapy for head and neck cancers has been discontinued due to lack of benefit. Chemoradiotherapy has been a standard treatment for this cancer type, but new approaches, including immunotherapy, have not been successful. The addition of xevinapant did not improve event-free survival for patients with advanced squamous…

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Cassava Sciences collaborator charged with defrauding NIH

A collaborator and paid consultant of Cassava Sciences, Hoau-Yan Wang, has been indicted for defrauding the National Institutes of Health in grant applications supporting the company’s Alzheimer’s drug, simufilam. Wang, a neuroscientist, published key papers supporting the drug’s effectiveness, but his work has been questioned by outside researchers for containing fabricated and falsified data. The…

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Philip Morris: Leaked documents show how company tries to influence science and policy on heated tobacco

Leaked documents from Philip Morris International suggest questionable research ethics and marketing practices for its heated tobacco products. Analysts note that the company’s claims of transparent science contradict the leaked documents, and products are being promoted as “reduced risk” despite evidence to the contrary. The Tobacco Control Research Group at the University of Bath found…

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Researchers develop scalable synthesis of cancer-fighting compounds

Withanolides are compounds found in plants that have shown promise in inhibiting cancer cell growth and preventing metastasis. However, obtaining these compounds in large quantities has been challenging. Researchers at Moffitt Cancer Center have developed a scalable synthesis method for withanolides, allowing for efficient production on a gram scale. This innovative approach eliminates the need…

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Penn researchers aim to uncover the underlying biological mechanisms of TBI-related neurodegeneration

A team of researchers led by Penn Medicine received a $10 million grant to study the link between traumatic brain injuries (TBI) and Alzheimer’s disease and related dementias (ADRD). The researchers aim to uncover the biological mechanisms of TBI-related neurodegeneration (TReND) using over 1,000 tissue samples. The new initiative, TRANSFORM-TBI, will investigate why TBIs increase…

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Revised Criteria for AD Diagnosis, Staging Released

A work group formed by the Alzheimer’s Association has updated the criteria for diagnosing and staging Alzheimer’s disease. The new criteria incorporate fluid and imaging biomarkers and aim to define the disease biologically rather than based on symptoms. Core biomarkers have been identified to measure neuropathologic changes and disease severity. The revised criteria provide flexibility…

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Chair appointed to epilepsy drug inquiry

The Government has appointed Bríd O’Flaherty BL to lead an inquiry into the use of sodium valproate among pregnant women in Ireland due to the high risk of developmental disorders and malformations in children exposed to the drug in the womb. The non-statutory inquiry will review the prescription of the drug and Ireland’s health service’s…

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AWS partners with EvolutionaryScale following its $142M raise

Amazon Web Services (AWS) is collaborating with EvolutionaryScale, an AI company, to provide access to ESM3 language models for drug discovery. EvolutionaryScale recently secured $142 million in funding with support from AWS and NVIDIA. ESM3 allows scientists to create new proteins and streamline protein design workflows. AWS customers can access the open-source version of ESM3…

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JAK, IL-6 inhibition most effective targeted therapies for VEXAS syndrome

A study conducted by Jerome Hadjadj, MD, PhD, and colleagues found that among targeted therapies, patients with VEXAS syndrome responded most overall to JAK inhibitors and IL-6 blockers. The study included 110 adults with VEXAS syndrome who received different targeted therapies, with JAK inhibitors showing the longest survival without treatment discontinuation. The researchers noted that…

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How can we get malaria control back on track?

Despite efforts to control malaria, the number of cases and deaths have increased in recent years, with the African region being the most severely affected. The World Health Organization aims to reduce both incidence and mortality rates by at least 75% by 2025 and 90% by 2030, but progress falls far short of these goals….

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5-mm Margin Excision Evaluated in Small Melanoma In Situ

A study conducted in Australia found that using 5-mm margins to manage small melanoma in situ (MIS) lesions on low-risk body sites resulted in a low local recurrence rate of 0.9%. This approach potentially reduces treatment-related morbidity and costs without compromising patient outcomes. The retrospective analysis included 351 MIS lesions from 292 patients with a…

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Know Symptoms, Steps For Prevention

The U.S. Centers for Disease Control and Prevention (CDC) has issued an urgent alert due to the increase in dengue fever cases worldwide, particularly in the Americas. The CDC has reported a record-breaking number of dengue cases in 2024, with more than 9.7 million cases being reported in the Americas alone. In the United States,…

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A Tipping Point: Organ Shortages and the Future of Transplantation

Transplant surgeons face challenges due to the critical shortage of organs, exacerbated by the Covid-19 pandemic. Medical advancements have improved success rates, but also increased demand. Living donor programs, paired donations, and new technologies aim to bridge the gap. Policy and education play a crucial role in increasing organ donations. Healthcare professionals need to support…

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