Nearly five years ago, the Covid-19 pandemic caused by the SARS-CoV-2 virus shook the global medical community with its highly contagious nature and lack of known treatment. Convalescent plasma proved to be a successful treatment for Covid-19 while other therapies and vaccines were being developed. Now, the H5N1 avian flu virus poses a potential threat, and lessons learned from the Covid-19 pandemic suggest that convalescent plasma could be a crucial early therapeutic option for future pandemics. To optimize its use, it is essential to apply the lessons learned and prepare for outpatient administration of high titer convalescent plasma at scale for early-stage diagnosed patients.
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