Coronary artery disease (CAD) is prevalent in patients with cirrhosis, but cirrhosis itself does not significantly increase the risk of CAD, according to a study published in the Journal of Clinical and Translational Hepatology. Through a review of 51 studies, researchers found that CAD, acute coronary syndromes, and myocardial infarction (MI) incidences were relatively low in patients with cirrhosis. Factors like nonalcoholic steatohepatitis, hepatitis C virus, advanced age, male sex, diabetes, hypertension, hyperlipidemia, smoking, and family history of CAD were associated with CAD in cirrhosis patients. The study suggests the need for large prospective studies to better understand and prevent CAD in this high-risk population.
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