Exercise with lower extremity blood flow restriction can enhance strength-related outcomes in athletes. A systematic review and meta-analysis of 20 studies involving 546 athletes found that most studies favored exercise with blood flow restriction over exercise alone. Significant improvements were reported in overall strength, muscle size, endurance, and sport-specific outcomes. The studies also showed that combining low-load exercise with blood flow restriction can lead to enhanced muscular hypertrophy and strength. These findings suggest that exercise with blood flow restriction creates a hypoxic-like environment within the muscle, enhancing muscle activation and promoting anabolic cell signaling.
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