Dr. Ray O’Connor reviews the latest clinical papers on HIV, highlighting the global impact of the virus with millions infected and deceased. Despite advances in antiretroviral therapy (ART), the development of an effective HIV vaccine remains challenging due to the virus’s genetic variability and latency. Clinical trials of potential vaccines have shown limited efficacy, leading to a bleak outlook for a successful vaccine in the near future. Other treatment strategies such as targeting the latent viral reservoir, enhancing Natural Killer cell function, gene therapy, and supplementation with selenium and zinc are being explored as possible avenues for combating HIV.
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