Researchers have identified new rejection categories in kidney transplantation that can improve patient risk assessment after a transplant. The findings highlight the role of microvascular inflammation in graft failure and the challenges it poses in clinical practice. The Banff classification has been updated to include new categories of microvascular inflammation in antibody-mediated rejection, leading to a more accurate diagnosis. A study of over 16,000 biopsies showed that patients reclassified into these new categories had a higher risk of graft failure. Recognizing these phenotypes could help personalize management for kidney transplant patients and improve outcomes.
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Examining the clinical significance of microvascular inflammation after kidney transplantation
