New research reveals heightened postprandial glucose and insulin levels in women using androgenic oral contraceptives, posing metabolic risks. A Nutrients study examined the impact of combined OCPs on glycemic response, linking OCP with metabolic syndrome (MetS) rise in women, impacting cardiometabolic health globally. The study gathered young women on monophasic OCPs, highlighting glucose homeostasis disparities between androgenic and anti-androgenic pill users. Findings indicated escalated postprandial glucose, insulin, and C-peptide levels in androgenic pill users. While similar studies noted increased glucose and C-peptide levels but lowered insulin, this study showcased heightened insulin secretion without increased clearance, proposing elevated insulin resistance under androgenic OCPs.
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