Fish oil supplementation, maternal genotype linked with childhood atopic dermatitis

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A study found that fish oil supplementation during pregnancy was associated with metabolites linked to inflammation. This effect was only seen in mothers with a specific genotype. The study included 635 mother-child pairs and showed that children born to mothers with the TT genotype who took fish oil had a reduced risk for atopic dermatitis (AD). On the other hand, children born to mothers with the CC genotype who took fish oil had a significantly higher risk for AD. These findings suggest that personalized prevention strategies, such as providing fish oil supplementation to pregnant mothers with specific genotypes, may help reduce the risk of AD in children.

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