A new study in Nicaragua found that previous infections with dengue and Zika viruses can impact a person’s future risk of getting sick with different types of dengue fever. Antibodies produced after infection can sometimes make a person more susceptible to severe illness from other dengue strains. The study highlighted the role of past infections and antibody levels in influencing susceptibility to dengue. This information could help in developing safer and more effective vaccines against dengue and similar viruses. Health officials need to consider pre-existing immunity and potential effects of previous infections when designing vaccination programs for dengue and Zika.
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