A review by Xia & He Publishing Inc. focuses on the diseases linked with subnormal levels of serum liver enzymes, such as AST, ALT, ALP, GGT, and 5′-NT. The study highlights conditions like vitamin B6 deficiency, chronic kidney disease, and genetic disorders that can lead to low enzyme levels. Additionally, it discusses various pathophysiologies behind enzyme deficiencies and their clinical significance. Recognizing these patterns early on can assist in the timely diagnosis and management of these conditions. Understanding the underlying mechanisms of enzyme deficiencies is crucial for developing targeted treatments and improving patient outcomes. The review emphasizes the importance of a comprehensive diagnostic approach in patients with subnormal liver enzyme levels.
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