Researchers at the National University of Singapore have developed a new method of delivering chemotherapy drugs directly to tumor sites using engineered bacteria. The bacteria bind specifically to cancer cells, carrying a prodrug that converts to an active drug at the tumor site. In preclinical models, this method reduced tumor growth by 67% and increased chemotherapy drug effectiveness by 54%. The researchers believe this approach could revolutionize cancer treatment by providing a more targeted, effective, and less toxic alternative to traditional chemotherapy. The findings were published in Nature Communications, offering hope for the development of new clinical treatments for cancer patients.
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Engineered bacteria deliver chemotherapy directly to tumors
