Researchers produce advanced multidimensional maps of gene regulation networks in the brain

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A consortium of researchers has created detailed maps of gene regulation networks in the brains of people with and without mental disorders. Using postmortem brain tissue from over 2,500 donors, the research sheds light on genetic risk factors for disorders like schizophrenia and depression. The findings, supported by the NIH, provide valuable resources for identifying potential therapeutics. The research is published in multiple scientific papers, exploring gene regulation at both the population and single-cell level in various brain regions. These discoveries offer new insights into how genes impact brain function and disorders, with the goal of advancing understanding and treatment options.

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