Newly found ‘molecular switch’ in lupus could aid treatment

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lupus is a complex autoimmune disease that can lead to organ damage and joint pain. New research suggests that a molecular switch can control the conversion of immune cells between helpful and harmful states, offering a potential treatment for lupus. The study found that the aryl hydrocarbon receptor (AHR) plays a crucial role in this process, with interferons exacerbating the imbalance. By targeting AHR, researchers hope to develop a more targeted approach to lupus treatment, potentially reducing unwanted side effects of broad immunosuppressive drugs. Further research is needed to determine the effectiveness of this approach in treating lupus and other autoimmune diseases.

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